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The map label for this gene is yncB [H]

Identifier: 77465536

GI number: 77465536

Start: 620593

End: 621621

Strand: Direct

Name: yncB [H]

Synonym: RSP_3537

Alternate gene names: 77465536

Gene position: 620593-621621 (Clockwise)

Preceding gene: 77465535

Following gene: 77465540

Centisome position: 65.81

GC content: 67.06

Gene sequence:

>1029_bases
ATGCCGCAGAGATCCGACATCAACCGCCGCGTGGTGCTGGCGCAGCGTCCGAAGGGCACGCCCGACGAAAGCACGCTCCG
GATGGAAGAGGTCCCCATTTCTGAGCCCGCCGAGGGGCAGATGCTCCTGCGGACGGTGTGGCTGTCGCTCGATCCCTACA
TGCGCGGGCGGATGAACGACACGAAATCCTATGCCAAGCCGGTCGAGATCGGCGGGGTGATGACCGGACAGGTGGTGGCC
GAGGTGATGCAGTCGAGCCTGCCCGGGTTCGAGGCCGGCGACATGGTTCTCGCGGGCAGCGGCTGGCAGGATTATGCGCT
GTCGGACGGGACCGAGGTGGTCAATCTCGGCAAGGCGCCCGAGCGTCCCTCGCGCGCGCTCGGCATCCTCGGGATGCCCG
GATACACCGCCTATGCAGGTCTTCTGAAGATCGGCGAGCCGCAGCCCGGAGAGACGGTGGTGGTCGCGGCGGCCTCCGGC
CCGGTGGGGGCCACGGTCGGGCAGATCGCGAAGCTGAAGGGCTGCCGTGCCGTGGGCGTTGCGGGCGGCGCCGACAAGTG
CCGGTATGTGGTCGAGACGCTGGGTTTCGACGCCTGCATCGACCACAGGGCGCCGGATTTCGAGGCGCAGCTCGCCGCCG
CCTGCCCGAACGGCATCGACATCTATTTCGAGAATGTCGGCGGCCGGGTCCTCTATGGCGTGCTGCCGCTCCTGAATCCG
TTCGCGCGGATGCCGGTCTGCGGCATCGTCTCCTGGTACAACAGTCCCGGCCTGCCCGAGGGGCCGGACATGGCGCCGGC
TCTCATGGGCACCATCCTGCGGATGAAGGTGAAGCTGCAGGGTTTCATCATCTTCGACAGTTTCCCGCGCAGCCTCTATG
CCGAATTCGCCCGCGAGATGACGGGCTGGCTGGCCGAGGGAAAGGTCAAATATCGCGAGCAGGTCGTCGAAGGGCTGGAG
GCCGCGCCGCAGGCGCTGAACGACCTGCTGGCGGGACGCAACTTCGGCAAGATGGTCGTGAAGCTCTAG

Upstream 100 bases:

>100_bases
CAGCCGCAGCCGTCGCGCGACGGTTGCGGCTTCTCCTGCTGCCGCACCTTCCCGAGCGGGGCTTCGGCACTACATCCGCC
CGGACAGCCGGGAGAAATAC

Downstream 100 bases:

>100_bases
GCGCAGCCCGGGCAGGCGCCCGCACCGGACCCGCTTCCCGGGGCAAGAGCCTCAGGGAGCGGGCTGGGTCTGTTTGAGAT
AGGCCAGATCGGCCGGATCG

Product: alcohol dehydrogenase, zinc-containing

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MPQRSDINRRVVLAQRPKGTPDESTLRMEEVPISEPAEGQMLLRTVWLSLDPYMRGRMNDTKSYAKPVEIGGVMTGQVVA
EVMQSSLPGFEAGDMVLAGSGWQDYALSDGTEVVNLGKAPERPSRALGILGMPGYTAYAGLLKIGEPQPGETVVVAAASG
PVGATVGQIAKLKGCRAVGVAGGADKCRYVVETLGFDACIDHRAPDFEAQLAAACPNGIDIYFENVGGRVLYGVLPLLNP
FARMPVCGIVSWYNSPGLPEGPDMAPALMGTILRMKVKLQGFIIFDSFPRSLYAEFAREMTGWLAEGKVKYREQVVEGLE
AAPQALNDLLAGRNFGKMVVKL

Sequences:

>Translated_342_residues
MPQRSDINRRVVLAQRPKGTPDESTLRMEEVPISEPAEGQMLLRTVWLSLDPYMRGRMNDTKSYAKPVEIGGVMTGQVVA
EVMQSSLPGFEAGDMVLAGSGWQDYALSDGTEVVNLGKAPERPSRALGILGMPGYTAYAGLLKIGEPQPGETVVVAAASG
PVGATVGQIAKLKGCRAVGVAGGADKCRYVVETLGFDACIDHRAPDFEAQLAAACPNGIDIYFENVGGRVLYGVLPLLNP
FARMPVCGIVSWYNSPGLPEGPDMAPALMGTILRMKVKLQGFIIFDSFPRSLYAEFAREMTGWLAEGKVKYREQVVEGLE
AAPQALNDLLAGRNFGKMVVKL
>Mature_341_residues
PQRSDINRRVVLAQRPKGTPDESTLRMEEVPISEPAEGQMLLRTVWLSLDPYMRGRMNDTKSYAKPVEIGGVMTGQVVAE
VMQSSLPGFEAGDMVLAGSGWQDYALSDGTEVVNLGKAPERPSRALGILGMPGYTAYAGLLKIGEPQPGETVVVAAASGP
VGATVGQIAKLKGCRAVGVAGGADKCRYVVETLGFDACIDHRAPDFEAQLAAACPNGIDIYFENVGGRVLYGVLPLLNPF
ARMPVCGIVSWYNSPGLPEGPDMAPALMGTILRMKVKLQGFIIFDSFPRSLYAEFAREMTGWLAEGKVKYREQVVEGLEA
APQALNDLLAGRNFGKMVVKL

Specific function: Unknown

COG id: COG2130

COG function: function code R; Putative NADP-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADP-dependent oxidoreductase L4BD family [H]

Homologues:

Organism=Homo sapiens, GI226059159, Length=339, Percent_Identity=36.5781710914454, Blast_Score=201, Evalue=6e-52,
Organism=Homo sapiens, GI226059133, Length=339, Percent_Identity=36.5781710914454, Blast_Score=201, Evalue=6e-52,
Organism=Homo sapiens, GI226246682, Length=345, Percent_Identity=33.9130434782609, Blast_Score=190, Evalue=1e-48,
Organism=Homo sapiens, GI226246680, Length=345, Percent_Identity=33.9130434782609, Blast_Score=190, Evalue=1e-48,
Organism=Homo sapiens, GI22748929, Length=345, Percent_Identity=33.9130434782609, Blast_Score=190, Evalue=1e-48,
Organism=Homo sapiens, GI226056130, Length=311, Percent_Identity=35.3697749196142, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI28557745, Length=335, Percent_Identity=26.2686567164179, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI194239674, Length=243, Percent_Identity=28.8065843621399, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI13236495, Length=243, Percent_Identity=28.8065843621399, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI226510941, Length=342, Percent_Identity=59.3567251461988, Blast_Score=426, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI133901712, Length=353, Percent_Identity=30.5949008498584, Blast_Score=169, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI133901710, Length=353, Percent_Identity=30.5949008498584, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17507255, Length=119, Percent_Identity=33.6134453781513, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323504, Length=338, Percent_Identity=26.0355029585799, Blast_Score=102, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00107 ADH_zinc_N [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36682; Mature: 36551

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQRSDINRRVVLAQRPKGTPDESTLRMEEVPISEPAEGQMLLRTVWLSLDPYMRGRMND
CCCCCCCCCEEEEEECCCCCCCHHCEEEECCCCCCCCCCHHHHHHHHHHCCHHHHCCCCC
TKSYAKPVEIGGVMTGQVVAEVMQSSLPGFEAGDMVLAGSGWQDYALSDGTEVVNLGKAP
HHHHCCCHHHCCEEHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCEEECCCCC
ERPSRALGILGMPGYTAYAGLLKIGEPQPGETVVVAAASGPVGATVGQIAKLKGCRAVGV
CCCCHHEEEECCCCHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEC
AGGADKCRYVVETLGFDACIDHRAPDFEAQLAAACPNGIDIYFENVGGRVLYGVLPLLNP
CCCHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCH
FARMPVCGIVSWYNSPGLPEGPDMAPALMGTILRMKVKLQGFIIFDSFPRSLYAEFAREM
HHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHEEEEEEEEEEECCCHHHHHHHHHHH
TGWLAEGKVKYREQVVEGLEAAPQALNDLLAGRNFGKMVVKL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEC
>Mature Secondary Structure 
PQRSDINRRVVLAQRPKGTPDESTLRMEEVPISEPAEGQMLLRTVWLSLDPYMRGRMND
CCCCCCCCEEEEEECCCCCCCHHCEEEECCCCCCCCCCHHHHHHHHHHCCHHHHCCCCC
TKSYAKPVEIGGVMTGQVVAEVMQSSLPGFEAGDMVLAGSGWQDYALSDGTEVVNLGKAP
HHHHCCCHHHCCEEHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCEEECCCCC
ERPSRALGILGMPGYTAYAGLLKIGEPQPGETVVVAAASGPVGATVGQIAKLKGCRAVGV
CCCCHHEEEECCCCHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEC
AGGADKCRYVVETLGFDACIDHRAPDFEAQLAAACPNGIDIYFENVGGRVLYGVLPLLNP
CCCHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCH
FARMPVCGIVSWYNSPGLPEGPDMAPALMGTILRMKVKLQGFIIFDSFPRSLYAEFAREM
HHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHEEEEEEEEEEECCCHHHHHHHHHHH
TGWLAEGKVKYREQVVEGLEAAPQALNDLLAGRNFGKMVVKL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]