Click here to switch to the map view.

The map label for this gene is aatB [H]

Identifier: 77465441

GI number: 77465441

Start: 509406

End: 510614

Strand: Direct

Name: aatB [H]

Synonym: RSP_3439

Alternate gene names: 77465441

Gene position: 509406-510614 (Clockwise)

Preceding gene: 77465440

Following gene: 77465442

Centisome position: 54.02

GC content: 69.31

Gene sequence:

>1209_bases
ATGACCAGCTCCCGCCTCTCCTCCCGCCTTCAGGCCGTGCAGCCCTCGCCCACCATCGCCATGACGCGCCTTGCAGCCCA
GCTCCGCCGCGAGGGCAAGGACATCATCGGCCTGTCGCAGGGCGAGCCCGATTTCGACACGCCCGTCCATATCCGGCAGG
CCGCGGCCGCCGCCATCGAGGCAGGCCAGACCCGCTACACCGACGTGGACGGCACGCCCGAGCTGAAGGCCGCCATCGTC
GAGAAATTCCGCCGCGAGAACGGGCTCTCCTACGAGACGAACCAGATCAGCGTCGGCACCGGCGGCAAGCAGGTGCTCTA
CAACGCGCTGCTGGCCACGCTCGACGAGGGCGACGAGGTGATCGTGCCCGCGCCCTACTGGGTCTCCTACCCCGACATGG
TGCGGCTCGCGGGCGGGGTGCCGGTCACCGTTTCCTGCCCCGAGGAGGACGATTTCCTGCTGACCGCGCCCGCGCTGCGG
GCCGCGATCACGCCGCGCACCAAATGGGTGATCCTGAACTCACCCTCGAACCCGACCGGCATGGGCTATTCGGCCGCCCA
TCTGCGCGCGCTGGCCGACGTGCTGCTCGAGTTCCCGCATGTGCTGGTGATGACCGACGACATGTACGAGCATCTGCGCT
ACGACGGCTGGGAATTCGCCACCATCGCGCAGGTCGAGCCGAAGCTCATGGACCGGGTGCTGACCTGCAACGGCGTGTCG
AAGGCCTTCTCGATGACCGGCTGGCGCATCGGCTATGCCGGGGGTCCGGCCGACATCATCAAGGCGATGGCCACGCTCCA
GTCGCAATCGACCTCGAACCCCTCCTCGGTGAGCCAGGCCGCGGCGCTCGCGGCCCTGACGGGGCCGATGGAGTTCCTGG
CCGAGCGCAACGAGATCTTCCGCCAGCGGCGCGACCTGTGCCTCTCGGCGCTGAACCAGATCGAGGGGCTGAGCTGCGTG
CGCCCGAACGGCGCCTTCTACCTCTTCCCCTCCTGCGCGGGCATGATCGGCCGCACCCGTCCCGACGGGCGCAAGATCGA
GACCGACACGGATTTCGTGATGTATCTCGTCGAGGAGGCGGGCGTGGCCGCGGTGCCGGGCAGCGCCTTCGGCCTCGCGC
CCTACTTCCGCATCTCCTTTGCCACCGACACCGAGCGGCTGCGCACCGCCTGCGAGCGGATCCGCGCGGCCTCGGCCCGG
CTGACCTGA

Upstream 100 bases:

>100_bases
GACCCTCCCCGGCAATGCCCCCGTCGAGATCCAGCTCATCGCCTCCGTCTGACAGAACCCGGGCCGGTCCGGCCCTCCAG
CCCCTCGGAACGCTCCCCAG

Downstream 100 bases:

>100_bases
GGCCGGGCCCCACAGCGGCCCTGCCGGCAGCGGCGGGCCCCAACCACGACAAGACGGAGACCGACATGGATCTGGGCATC
AGAGGCAAGACGGCGCTGGT

Product: aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MTSSRLSSRLQAVQPSPTIAMTRLAAQLRREGKDIIGLSQGEPDFDTPVHIRQAAAAAIEAGQTRYTDVDGTPELKAAIV
EKFRRENGLSYETNQISVGTGGKQVLYNALLATLDEGDEVIVPAPYWVSYPDMVRLAGGVPVTVSCPEEDDFLLTAPALR
AAITPRTKWVILNSPSNPTGMGYSAAHLRALADVLLEFPHVLVMTDDMYEHLRYDGWEFATIAQVEPKLMDRVLTCNGVS
KAFSMTGWRIGYAGGPADIIKAMATLQSQSTSNPSSVSQAAALAALTGPMEFLAERNEIFRQRRDLCLSALNQIEGLSCV
RPNGAFYLFPSCAGMIGRTRPDGRKIETDTDFVMYLVEEAGVAAVPGSAFGLAPYFRISFATDTERLRTACERIRAASAR
LT

Sequences:

>Translated_402_residues
MTSSRLSSRLQAVQPSPTIAMTRLAAQLRREGKDIIGLSQGEPDFDTPVHIRQAAAAAIEAGQTRYTDVDGTPELKAAIV
EKFRRENGLSYETNQISVGTGGKQVLYNALLATLDEGDEVIVPAPYWVSYPDMVRLAGGVPVTVSCPEEDDFLLTAPALR
AAITPRTKWVILNSPSNPTGMGYSAAHLRALADVLLEFPHVLVMTDDMYEHLRYDGWEFATIAQVEPKLMDRVLTCNGVS
KAFSMTGWRIGYAGGPADIIKAMATLQSQSTSNPSSVSQAAALAALTGPMEFLAERNEIFRQRRDLCLSALNQIEGLSCV
RPNGAFYLFPSCAGMIGRTRPDGRKIETDTDFVMYLVEEAGVAAVPGSAFGLAPYFRISFATDTERLRTACERIRAASAR
LT
>Mature_401_residues
TSSRLSSRLQAVQPSPTIAMTRLAAQLRREGKDIIGLSQGEPDFDTPVHIRQAAAAAIEAGQTRYTDVDGTPELKAAIVE
KFRRENGLSYETNQISVGTGGKQVLYNALLATLDEGDEVIVPAPYWVSYPDMVRLAGGVPVTVSCPEEDDFLLTAPALRA
AITPRTKWVILNSPSNPTGMGYSAAHLRALADVLLEFPHVLVMTDDMYEHLRYDGWEFATIAQVEPKLMDRVLTCNGVSK
AFSMTGWRIGYAGGPADIIKAMATLQSQSTSNPSSVSQAAALAALTGPMEFLAERNEIFRQRRDLCLSALNQIEGLSCVR
PNGAFYLFPSCAGMIGRTRPDGRKIETDTDFVMYLVEEAGVAAVPGSAFGLAPYFRISFATDTERLRTACERIRAASARL
T

Specific function: Involved in symbiotic nitrogen fixation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=431, Percent_Identity=28.538283062645, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI169881279, Length=431, Percent_Identity=28.538283062645, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI56713256, Length=421, Percent_Identity=27.5534441805226, Blast_Score=156, Evalue=4e-38,
Organism=Homo sapiens, GI56713254, Length=432, Percent_Identity=27.5462962962963, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI169881281, Length=428, Percent_Identity=25.9345794392523, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI4507369, Length=376, Percent_Identity=25, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI19263340, Length=351, Percent_Identity=22.5071225071225, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI215599424, Length=351, Percent_Identity=22.5071225071225, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1786816, Length=385, Percent_Identity=30.3896103896104, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1788627, Length=393, Percent_Identity=27.9898218829517, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1788722, Length=399, Percent_Identity=28.8220551378446, Blast_Score=142, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI17567663, Length=385, Percent_Identity=25.7142857142857, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17567369, Length=360, Percent_Identity=25, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71994472, Length=380, Percent_Identity=24.7368421052632, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI71994476, Length=380, Percent_Identity=24.7368421052632, Blast_Score=111, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6322401, Length=390, Percent_Identity=24.6153846153846, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6320317, Length=354, Percent_Identity=24.0112994350282, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28573069, Length=425, Percent_Identity=27.5294117647059, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24646114, Length=425, Percent_Identity=27.5294117647059, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI28573067, Length=425, Percent_Identity=27.5294117647059, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI28573065, Length=425, Percent_Identity=27.5294117647059, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI18859735, Length=379, Percent_Identity=25.5936675461741, Blast_Score=112, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43663; Mature: 43532

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSRLSSRLQAVQPSPTIAMTRLAAQLRREGKDIIGLSQGEPDFDTPVHIRQAAAAAIE
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHHH
AGQTRYTDVDGTPELKAAIVEKFRRENGLSYETNQISVGTGGKQVLYNALLATLDEGDEV
CCCCEECCCCCCHHHHHHHHHHHHHHCCCCEECCEEEECCCHHHHHHHHHHHHHCCCCEE
IVPAPYWVSYPDMVRLAGGVPVTVSCPEEDDFLLTAPALRAAITPRTKWVILNSPSNPTG
EECCCCCCCCHHHHHHCCCCEEEEECCCCCCEEEECHHHHHHCCCCEEEEEEECCCCCCC
MGYSAAHLRALADVLLEFPHVLVMTDDMYEHLRYDGWEFATIAQVEPKLMDRVLTCNGVS
CCCHHHHHHHHHHHHHHCCCEEEEEHHHHHHHCCCCCCEEEEECCCHHHHHHHHHCCCHH
KAFSMTGWRIGYAGGPADIIKAMATLQSQSTSNPSSVSQAAALAALTGPMEFLAERNEIF
HHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQRRDLCLSALNQIEGLSCVRPNGAFYLFPSCAGMIGRTRPDGRKIETDTDFVMYLVEEA
HHHHHHHHHHHHHHCCCEEECCCCCEEECCCHHHHHCCCCCCCCEECCCCHHHHHHHHHC
GVAAVPGSAFGLAPYFRISFATDTERLRTACERIRAASARLT
CCEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TSSRLSSRLQAVQPSPTIAMTRLAAQLRREGKDIIGLSQGEPDFDTPVHIRQAAAAAIE
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHHH
AGQTRYTDVDGTPELKAAIVEKFRRENGLSYETNQISVGTGGKQVLYNALLATLDEGDEV
CCCCEECCCCCCHHHHHHHHHHHHHHCCCCEECCEEEECCCHHHHHHHHHHHHHCCCCEE
IVPAPYWVSYPDMVRLAGGVPVTVSCPEEDDFLLTAPALRAAITPRTKWVILNSPSNPTG
EECCCCCCCCHHHHHHCCCCEEEEECCCCCCEEEECHHHHHHCCCCEEEEEEECCCCCCC
MGYSAAHLRALADVLLEFPHVLVMTDDMYEHLRYDGWEFATIAQVEPKLMDRVLTCNGVS
CCCHHHHHHHHHHHHHHCCCEEEEEHHHHHHHCCCCCCEEEEECCCHHHHHHHHHCCCHH
KAFSMTGWRIGYAGGPADIIKAMATLQSQSTSNPSSVSQAAALAALTGPMEFLAERNEIF
HHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQRRDLCLSALNQIEGLSCVRPNGAFYLFPSCAGMIGRTRPDGRKIETDTDFVMYLVEEA
HHHHHHHHHHHHHHCCCEEECCCCCEEECCCHHHHHCCCCCCCCEECCCCHHHHHHHHHC
GVAAVPGSAFGLAPYFRISFATDTERLRTACERIRAASARLT
CCEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]