BacMap

Definition	Rhodobacter sphaeroides 2.4.1 chromosome 2, complete sequence.
Accession	NC_007494
Length	943,016

Click here to switch to the map view.

The map label for this gene is fabG [H]

Identifier: 77465442

GI number: 77465442

Start: 510680

End: 511465

Strand: Direct

Name: fabG [H]

Synonym: RSP_3440

Alternate gene names: 77465442

Gene position: 510680-511465 (Clockwise)

Preceding gene: 77465441

Following gene: 77465443

Centisome position: 54.15

GC content: 72.52

Gene sequence:

>786_bases
ATGGATCTGGGCATCAGAGGCAAGACGGCGCTGGTTCTGGGCGCGGGCGGGGGCCTCGGCGGCGCCATCGCCCGCTCGCT
CGCCCGCGAGGGCGCGCGGGTGGCGCTCGGCGACATCGACCTCGCCGCGGCCGAAGCCACCGCCGAGGCGATCCGGGCCG
AGGGCGGCACGGCGCTGCCGCTCGCCTGGGATCTGGCCGACCTCGGCGCCATCGAGACGAACGTGAGCCTGATCGAGGCC
GAGCTGGGCCCGGTCGACATCCTCGTGAACAACACGGGCGGGCCGAAGCCCTCGCCGATCGCCGGGCAGGAGGCCGCGCT
CTGGCGCGCGAGCTTCGAGTCCATGGTGCTCTCGGTCATCTCCATCACCGACCGCGTGCTGCCGGGCATGAAGGCCCGCA
AATGGGGCCGCATCATCACCTCGACCTCGTCGGGCGTGGTGGCGCCGATCCCGAACCTCGGCCTGTCGAACGCGCTGCGC
ATCTCGCTCGTGGGCTGGTCGAAGACGCTCGCGCGCGAGGTGGGCCGCGACGGCATCACGGCCAACGTCGTGCTGCCCGG
CCGCGTCGCCACCAAGCGCATCACCTTCCTCGACGAGCAGAAGGCCGCGCGCGAAGGCCGGGCCGTGGCCGAAGTGGCCG
CCGAGAGCGTGGCCTCGATCCCGCTCGGCCGCTATGGTCAGCCCGAGGAATATGGCGATGCCGTGGCCTTCCTCGCCTCG
GCCCGCGCCTCCTACATCACCGGCAGCACCATCCGCATCGACGGCGGCCTGATCGCCAGCGTCTGA

Upstream 100 bases:

>100_bases
AGCGGATCCGCGCGGCCTCGGCCCGGCTGACCTGAGGCCGGGCCCCACAGCGGCCCTGCCGGCAGCGGCGGGCCCCAACC
ACGACAAGACGGAGACCGAC

Downstream 100 bases:

>100_bases
CCCCAAAGGAAACAGAATGACCACCGACACCGCCAAGGAACAGGCCCTGATCGAGGCGCTGCGCGGCGTGACCACCGCGA
CGCTCACCACCGTCCTTCTG

Product: putative short chain dehydrogenase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MDLGIRGKTALVLGAGGGLGGAIARSLAREGARVALGDIDLAAAEATAEAIRAEGGTALPLAWDLADLGAIETNVSLIEA
ELGPVDILVNNTGGPKPSPIAGQEAALWRASFESMVLSVISITDRVLPGMKARKWGRIITSTSSGVVAPIPNLGLSNALR
ISLVGWSKTLAREVGRDGITANVVLPGRVATKRITFLDEQKAAREGRAVAEVAAESVASIPLGRYGQPEEYGDAVAFLAS
ARASYITGSTIRIDGGLIASV

Sequences:

>Translated_261_residues
MDLGIRGKTALVLGAGGGLGGAIARSLAREGARVALGDIDLAAAEATAEAIRAEGGTALPLAWDLADLGAIETNVSLIEA
ELGPVDILVNNTGGPKPSPIAGQEAALWRASFESMVLSVISITDRVLPGMKARKWGRIITSTSSGVVAPIPNLGLSNALR
ISLVGWSKTLAREVGRDGITANVVLPGRVATKRITFLDEQKAAREGRAVAEVAAESVASIPLGRYGQPEEYGDAVAFLAS
ARASYITGSTIRIDGGLIASV
>Mature_261_residues
MDLGIRGKTALVLGAGGGLGGAIARSLAREGARVALGDIDLAAAEATAEAIRAEGGTALPLAWDLADLGAIETNVSLIEA
ELGPVDILVNNTGGPKPSPIAGQEAALWRASFESMVLSVISITDRVLPGMKARKWGRIITSTSSGVVAPIPNLGLSNALR
ISLVGWSKTLAREVGRDGITANVVLPGRVATKRITFLDEQKAAREGRAVAEVAAESVASIPLGRYGQPEEYGDAVAFLAS
ARASYITGSTIRIDGGLIASV

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=265, Percent_Identity=30.5660377358491, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI32483357, Length=257, Percent_Identity=29.1828793774319, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI40254992, Length=252, Percent_Identity=30.5555555555556, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI7705925, Length=263, Percent_Identity=29.277566539924, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI5031737, Length=253, Percent_Identity=29.2490118577075, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=26.9230769230769, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI142976729, Length=191, Percent_Identity=27.7486910994764, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI210032110, Length=188, Percent_Identity=29.2553191489362, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI109715829, Length=227, Percent_Identity=29.0748898678414, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI4503301, Length=262, Percent_Identity=29.0076335877863, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI33667109, Length=211, Percent_Identity=29.3838862559242, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI126723750, Length=262, Percent_Identity=25.1908396946565, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI66933014, Length=232, Percent_Identity=27.1551724137931, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI4504505, Length=199, Percent_Identity=30.6532663316583, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI31542939, Length=196, Percent_Identity=29.5918367346939, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787335, Length=259, Percent_Identity=38.996138996139, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1787905, Length=255, Percent_Identity=29.0196078431373, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=32.4110671936759, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1790717, Length=263, Percent_Identity=25.8555133079848, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788459, Length=257, Percent_Identity=28.4046692607004, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1789208, Length=265, Percent_Identity=28.6792452830189, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87082160, Length=264, Percent_Identity=28.030303030303, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789378, Length=256, Percent_Identity=28.125, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1789057, Length=258, Percent_Identity=28.2945736434109, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=26.3565891472868, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI2367365, Length=256, Percent_Identity=30.46875, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=257, Percent_Identity=31.1284046692607, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17560676, Length=265, Percent_Identity=29.4339622641509, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17555706, Length=255, Percent_Identity=29.8039215686275, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI25147288, Length=253, Percent_Identity=26.8774703557312, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17562910, Length=265, Percent_Identity=32.0754716981132, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=28, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=275, Percent_Identity=29.8181818181818, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17536025, Length=269, Percent_Identity=31.2267657992565, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17538486, Length=266, Percent_Identity=30.8270676691729, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17568967, Length=201, Percent_Identity=29.8507462686567, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17536651, Length=266, Percent_Identity=30.8270676691729, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=29.1187739463602, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17565030, Length=260, Percent_Identity=30.3846153846154, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=258, Percent_Identity=27.906976744186, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=260, Percent_Identity=26.9230769230769, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193203115, Length=196, Percent_Identity=30.6122448979592, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=269, Percent_Identity=28.2527881040892, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=198, Percent_Identity=30.3030303030303, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=258, Percent_Identity=27.906976744186, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=259, Percent_Identity=27.4131274131274, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=261, Percent_Identity=26.8199233716475, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=187, Percent_Identity=28.8770053475936, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=272, Percent_Identity=26.8382352941176, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=273, Percent_Identity=26.3736263736264, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=254, Percent_Identity=25.9842519685039, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17561272, Length=263, Percent_Identity=30.4182509505703, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=257, Percent_Identity=24.124513618677, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=265, Percent_Identity=27.5471698113208, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=255, Percent_Identity=28.6274509803922, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=208, Percent_Identity=28.3653846153846, Blast_Score=70, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24639444, Length=262, Percent_Identity=30.1526717557252, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI23397609, Length=260, Percent_Identity=33.4615384615385, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21355319, Length=262, Percent_Identity=28.6259541984733, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21357041, Length=253, Percent_Identity=27.6679841897233, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24584744, Length=197, Percent_Identity=31.9796954314721, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28574402, Length=197, Percent_Identity=31.9796954314721, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI18859837, Length=233, Percent_Identity=30.0429184549356, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI161076933, Length=199, Percent_Identity=31.6582914572864, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24584748, Length=199, Percent_Identity=31.6582914572864, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28571526, Length=253, Percent_Identity=26.4822134387352, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24644337, Length=176, Percent_Identity=31.8181818181818, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24649181, Length=206, Percent_Identity=30.0970873786408, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21355631, Length=175, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24643142, Length=260, Percent_Identity=28.8461538461538, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=24.3137254901961, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 26717; Mature: 26717

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLGIRGKTALVLGAGGGLGGAIARSLAREGARVALGDIDLAAAEATAEAIRAEGGTALP
CCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCCCCCE
LAWDLADLGAIETNVSLIEAELGPVDILVNNTGGPKPSPIAGQEAALWRASFESMVLSVI
EEECHHHCCCHHCCCEEEEECCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
SITDRVLPGMKARKWGRIITSTSSGVVAPIPNLGLSNALRISLVGWSKTLAREVGRDGIT
HHHHHHCCCCCHHHCCCEEEECCCCEEECCCCCCCCCEEEEEEECCHHHHHHHHCCCCCE
ANVVLPGRVATKRITFLDEQKAAREGRAVAEVAAESVASIPLGRYGQPEEYGDAVAFLAS
EEEEECCCHHHHEEEEHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
ARASYITGSTIRIDGGLIASV
HHHHEECCCEEEECCCEEECC
>Mature Secondary Structure
MDLGIRGKTALVLGAGGGLGGAIARSLAREGARVALGDIDLAAAEATAEAIRAEGGTALP
CCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCCCCCE
LAWDLADLGAIETNVSLIEAELGPVDILVNNTGGPKPSPIAGQEAALWRASFESMVLSVI
EEECHHHCCCHHCCCEEEEECCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
SITDRVLPGMKARKWGRIITSTSSGVVAPIPNLGLSNALRISLVGWSKTLAREVGRDGIT
HHHHHHCCCCCHHHCCCEEEECCCCEEECCCCCCCCCEEEEEEECCHHHHHHHHCCCCCE
ANVVLPGRVATKRITFLDEQKAAREGRAVAEVAAESVASIPLGRYGQPEEYGDAVAFLAS
EEEEECCCHHHHEEEEHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
ARASYITGSTIRIDGGLIASV
HHHHEECCCEEEECCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1556094; 8905232; 9278503; 1314802 [H]