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The map label for this gene is mcpG [H]

Identifier: 77465309

GI number: 77465309

Start: 363644

End: 365248

Strand: Direct

Name: mcpG [H]

Synonym: RSP_3303

Alternate gene names: 77465309

Gene position: 363644-365248 (Clockwise)

Preceding gene: 77465308

Following gene: 77465311

Centisome position: 38.56

GC content: 70.16

Gene sequence:

>1605_bases
ATGAGACTCTCGATCCGCAACAAGCTGGGGGCGAGCTTTCTCGTCGTCTTCGCCATGGCGGGCACGACCAACCTTTATGC
GCTCTACACGATCAACAGGCTGAACGACGACATGGCCATCCTCGTCACCCGCGATTTCGAGCGCGTGCGGCTGGCCGAGC
GGCTGAATGCCGAGCAGCTGCGCATGAAAAGCGCGATTCGCGACCACATGCTCTCGCCCCCCGCCGGCAAGGCTGCCGAG
AAGGCAGAGGTGGCTGCGGCGCGGGCGAATATGCGCGAAAGCTTCGATTCGCTCGTGGCGACGTCGCCGGAGGCGGACCT
GGCGGCGCTGGCCGAGTACGAGGATCTCTGGACCCAGTCGATCCGCGTCAACGACAAGGCCCTGCTCCTGTCGGAGGAGG
GCCGGACCGAAGAGGCGCGCAAGCTCCTCTGGGGCGACTATTTCACCCGCCTGCAGGCCAGCCGGATGGAGATCATGGAG
GGGCTGCGCGACCGGAGCCTCGTCGCGCTGAAGGCGACCCAGGCCGAGGCGGCCGAGGCGCGTCGCCTGACGGTGCTGCT
GATGGCGAGCTCCATCGCGGCGGGAACTCTGATCGCCTTCCTCGCGGCGGGCTGGCTGATCCTCTCGATCGGGCGCGGCC
TCGGCCGGGCGCTGGCGCTGGCGCGGCGGGTGGCGGACGGGGACCTGACCGAGACGGCCGTGCTGCGGGGCAATGACGAG
ATCACCGACCTTCTCCGCGCGCTCAATGCGATGGTGGTGCGGCTGCGCGATGTGGTGGGCCGCGTCACCGCCGCCGTGGG
CGACGTGGCCTCGGGCAGTGCCGAGGTCGCCGCCACGTCCGAGCAGTTGAGCCAGGGCGCGAGCGAACAGGCGGCCGCGA
CCGTGCAGGCCTCGGCCTCCGTCGAGGAAATCGCCGCAACTGTCCGGCAGAGTGCGGAAAATTCCGGCCAGACCGAGCGG
ATGGCGCGGTCTTCGGCCGAAGCGGCCCGGCAGAGCGGCGCGGCCGTCTCGGATGCCGTATCGGCGATGCGCGGCATCGC
CGAGCGGATCCATGTCGTGCAGGAGATCGCCCGCCAGACGGACCTTCTGGCGCTGAATGCCGCGGTCGAGGCGGCGCGGG
CGGGCGAGCACGGGCGGGGCTTTGCCGTGGTGGCCACGGAGGTCCGCCGGCTGGCGGAGCGGAGCCAGGCCGCCGCGGCC
GAGATCTCGGATCTGTCCTCCGCCACCGCGCGCTCGGCGGTGGCCGCGGGCGGGATGATCGAAAACCTCGTGCCCGACAT
CGCGCGGACGGCCGACCTTGTTTCCGACATTTCTTCGGCTTCGCAAGAGCTTGCGGCGGGTGCTTCACAAGTGAGCCAGG
CCCTTCACCAGCTCGATACGGTGACGCAGCAGAACACGGCCGCGGCGAGCGAGCTTTCGGGCCGGGCCGCGGATCTGTCG
GAACGGTCGGAGGATCTGCGCGCGGCCGTCAGCTACTTCCGCACCGGCGGTCCCGCGGTGCAGGCGCCGCTCAAGGCCGA
GAGAACGACCCTGATGCAGAGGGACTCCGATGCACGGCTTGAGGAGGATCTGGACGCGGCCTTCGCGCGAGCGCGCGTCG
CGTGA

Upstream 100 bases:

>100_bases
CCTGGCTTTCGACCAGTGGGGGCAGAGTGTGTGGGTGCCCCGGTTCGCCCCAGTCCGGCAGAGGCCCTGAGGCCCGCCGG
CTCTACAGGAAAGTACCGCC

Downstream 100 bases:

>100_bases
GCATCAGGGCGCGGCTCCGCCGCGCCGGAAGTGTCAGCTGAAGACCAGCAGGATCGCGATCAGCACCGAGGCCGCGACGA
AGACCGATCCCATGAGCGAG

Product: putative methyl accepting chemotaxis protein, McpG

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 534; Mature: 534

Protein sequence:

>534_residues
MRLSIRNKLGASFLVVFAMAGTTNLYALYTINRLNDDMAILVTRDFERVRLAERLNAEQLRMKSAIRDHMLSPPAGKAAE
KAEVAAARANMRESFDSLVATSPEADLAALAEYEDLWTQSIRVNDKALLLSEEGRTEEARKLLWGDYFTRLQASRMEIME
GLRDRSLVALKATQAEAAEARRLTVLLMASSIAAGTLIAFLAAGWLILSIGRGLGRALALARRVADGDLTETAVLRGNDE
ITDLLRALNAMVVRLRDVVGRVTAAVGDVASGSAEVAATSEQLSQGASEQAAATVQASASVEEIAATVRQSAENSGQTER
MARSSAEAARQSGAAVSDAVSAMRGIAERIHVVQEIARQTDLLALNAAVEAARAGEHGRGFAVVATEVRRLAERSQAAAA
EISDLSSATARSAVAAGGMIENLVPDIARTADLVSDISSASQELAAGASQVSQALHQLDTVTQQNTAAASELSGRAADLS
ERSEDLRAAVSYFRTGGPAVQAPLKAERTTLMQRDSDARLEEDLDAAFARARVA

Sequences:

>Translated_534_residues
MRLSIRNKLGASFLVVFAMAGTTNLYALYTINRLNDDMAILVTRDFERVRLAERLNAEQLRMKSAIRDHMLSPPAGKAAE
KAEVAAARANMRESFDSLVATSPEADLAALAEYEDLWTQSIRVNDKALLLSEEGRTEEARKLLWGDYFTRLQASRMEIME
GLRDRSLVALKATQAEAAEARRLTVLLMASSIAAGTLIAFLAAGWLILSIGRGLGRALALARRVADGDLTETAVLRGNDE
ITDLLRALNAMVVRLRDVVGRVTAAVGDVASGSAEVAATSEQLSQGASEQAAATVQASASVEEIAATVRQSAENSGQTER
MARSSAEAARQSGAAVSDAVSAMRGIAERIHVVQEIARQTDLLALNAAVEAARAGEHGRGFAVVATEVRRLAERSQAAAA
EISDLSSATARSAVAAGGMIENLVPDIARTADLVSDISSASQELAAGASQVSQALHQLDTVTQQNTAAASELSGRAADLS
ERSEDLRAAVSYFRTGGPAVQAPLKAERTTLMQRDSDARLEEDLDAAFARARVA
>Mature_534_residues
MRLSIRNKLGASFLVVFAMAGTTNLYALYTINRLNDDMAILVTRDFERVRLAERLNAEQLRMKSAIRDHMLSPPAGKAAE
KAEVAAARANMRESFDSLVATSPEADLAALAEYEDLWTQSIRVNDKALLLSEEGRTEEARKLLWGDYFTRLQASRMEIME
GLRDRSLVALKATQAEAAEARRLTVLLMASSIAAGTLIAFLAAGWLILSIGRGLGRALALARRVADGDLTETAVLRGNDE
ITDLLRALNAMVVRLRDVVGRVTAAVGDVASGSAEVAATSEQLSQGASEQAAATVQASASVEEIAATVRQSAENSGQTER
MARSSAEAARQSGAAVSDAVSAMRGIAERIHVVQEIARQTDLLALNAAVEAARAGEHGRGFAVVATEVRRLAERSQAAAA
EISDLSSATARSAVAAGGMIENLVPDIARTADLVSDISSASQELAAGASQVSQALHQLDTVTQQNTAAASELSGRAADLS
ERSEDLRAAVSYFRTGGPAVQAPLKAERTTLMQRDSDARLEEDLDAAFARARVA

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=321, Percent_Identity=38.9408099688474, Blast_Score=172, Evalue=6e-44,
Organism=Escherichia coli, GI1788195, Length=322, Percent_Identity=38.5093167701863, Blast_Score=164, Evalue=2e-41,
Organism=Escherichia coli, GI2367378, Length=367, Percent_Identity=36.2397820163488, Blast_Score=161, Evalue=8e-41,
Organism=Escherichia coli, GI1788194, Length=338, Percent_Identity=34.9112426035503, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI1789453, Length=312, Percent_Identity=32.0512820512821, Blast_Score=134, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 56628; Mature: 56628

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLSIRNKLGASFLVVFAMAGTTNLYALYTINRLNDDMAILVTRDFERVRLAERLNAEQL
CCCCCHHHHCHHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEECCHHHHHHHHHCCHHHH
RMKSAIRDHMLSPPAGKAAEKAEVAAARANMRESFDSLVATSPEADLAALAEYEDLWTQS
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
IRVNDKALLLSEEGRTEEARKLLWGDYFTRLQASRMEIMEGLRDRSLVALKATQAEAAEA
HEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHH
RRLTVLLMASSIAAGTLIAFLAAGWLILSIGRGLGRALALARRVADGDLTETAVLRGNDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHH
ITDLLRALNAMVVRLRDVVGRVTAAVGDVASGSAEVAATSEQLSQGASEQAAATVQASAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHCCCCHHHHHHHHHHHH
VEEIAATVRQSAENSGQTERMARSSAEAARQSGAAVSDAVSAMRGIAERIHVVQEIARQT
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DLLALNAAVEAARAGEHGRGFAVVATEVRRLAERSQAAAAEISDLSSATARSAVAAGGMI
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
ENLVPDIARTADLVSDISSASQELAAGASQVSQALHQLDTVTQQNTAAASELSGRAADLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ERSEDLRAAVSYFRTGGPAVQAPLKAERTTLMQRDSDARLEEDLDAAFARARVA
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRLSIRNKLGASFLVVFAMAGTTNLYALYTINRLNDDMAILVTRDFERVRLAERLNAEQL
CCCCCHHHHCHHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEECCHHHHHHHHHCCHHHH
RMKSAIRDHMLSPPAGKAAEKAEVAAARANMRESFDSLVATSPEADLAALAEYEDLWTQS
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
IRVNDKALLLSEEGRTEEARKLLWGDYFTRLQASRMEIMEGLRDRSLVALKATQAEAAEA
HEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHH
RRLTVLLMASSIAAGTLIAFLAAGWLILSIGRGLGRALALARRVADGDLTETAVLRGNDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHH
ITDLLRALNAMVVRLRDVVGRVTAAVGDVASGSAEVAATSEQLSQGASEQAAATVQASAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHCCCCHHHHHHHHHHHH
VEEIAATVRQSAENSGQTERMARSSAEAARQSGAAVSDAVSAMRGIAERIHVVQEIARQT
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DLLALNAAVEAARAGEHGRGFAVVATEVRRLAERSQAAAAEISDLSSATARSAVAAGGMI
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
ENLVPDIARTADLVSDISSASQELAAGASQVSQALHQLDTVTQQNTAAASELSGRAADLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ERSEDLRAAVSYFRTGGPAVQAPLKAERTTLMQRDSDARLEEDLDAAFARARVA
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]