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The map label for this gene is iorA [H]

Identifier: 77465178

GI number: 77465178

Start: 219127

End: 219585

Strand: Reverse

Name: iorA [H]

Synonym: RSP_3164

Alternate gene names: 77465178

Gene position: 219585-219127 (Counterclockwise)

Preceding gene: 77465179

Following gene: 77465177

Centisome position: 23.29

GC content: 69.5

Gene sequence:

>459_bases
ATGATCCACCTGACCGTCAACGGGCGCGAGATGTCCCTCGACGTCGATCCCGACACCCCTCTGCTCTGGGTCCTGCGCGA
CGAGCTGCGCCTGACCGGCACGAAGTTCGGTTGCGGGGTCGCCCAGTGCGGGGCCTGCACCGTCATGCTGGACGGGATGC
CCCGACGGTCCTGCGTGACGCCGGTCGGGATGATCGAAAATGCGTCCGTCACCACCATCGAGGGGATGGAGGGGCCGGAG
ATCTCCGCCGTGCAGGCCGCCTGGGCCGCGTCGGACGTGCCGCAATGCGGCTGGTGCCAGTCGGGCCAGGTGATGTCGGC
GACCGCGCTCCTGCGCCAGATCCCGAAGCCCACCGACGAGGAGATCGATCACGCGATGGGCGGCAACCTCTGCCGCTGCG
CCACCTATGTCCGCATCCGGCAGGCGATCCATGACGCCGCCCGCACCCTGGAGGGCTGA

Upstream 100 bases:

>100_bases
CGCGAGGCCGGCTGAGCGGAAAGCTCCGCCGAGGGAGCGCGACCTCTTGACGCAGCGCCTTCGGCCGCTAGGTGGCCGCC
AAAGCCACCGGGAGGCCGCC

Downstream 100 bases:

>100_bases
GCCATGACCATGCTCTCGCGCCGCCGCTTCCTCGCCTCGACCGCGGGCTTCACCCTCGCCCTCGTGCTGCCCACTCCCTT
CGCCCGGGCGCAGGGCGCGC

Product: ferredoxin like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MIHLTVNGREMSLDVDPDTPLLWVLRDELRLTGTKFGCGVAQCGACTVMLDGMPRRSCVTPVGMIENASVTTIEGMEGPE
ISAVQAAWAASDVPQCGWCQSGQVMSATALLRQIPKPTDEEIDHAMGGNLCRCATYVRIRQAIHDAARTLEG

Sequences:

>Translated_152_residues
MIHLTVNGREMSLDVDPDTPLLWVLRDELRLTGTKFGCGVAQCGACTVMLDGMPRRSCVTPVGMIENASVTTIEGMEGPE
ISAVQAAWAASDVPQCGWCQSGQVMSATALLRQIPKPTDEEIDHAMGGNLCRCATYVRIRQAIHDAARTLEG
>Mature_152_residues
MIHLTVNGREMSLDVDPDTPLLWVLRDELRLTGTKFGCGVAQCGACTVMLDGMPRRSCVTPVGMIENASVTTIEGMEGPE
ISAVQAAWAASDVPQCGWCQSGQVMSATALLRQIPKPTDEEIDHAMGGNLCRCATYVRIRQAIHDAARTLEG

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=156, Percent_Identity=43.5897435897436, Blast_Score=96, Evalue=9e-21,
Organism=Homo sapiens, GI71773480, Length=158, Percent_Identity=43.6708860759494, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1786480, Length=160, Percent_Identity=43.125, Blast_Score=124, Evalue=2e-30,
Organism=Escherichia coli, GI1789232, Length=151, Percent_Identity=40.3973509933775, Blast_Score=100, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17540638, Length=154, Percent_Identity=40.2597402597403, Blast_Score=109, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17539860, Length=155, Percent_Identity=38.7096774193548, Blast_Score=105, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI32566215, Length=155, Percent_Identity=36.7741935483871, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI17737937, Length=146, Percent_Identity=40.4109589041096, Blast_Score=103, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24647193, Length=160, Percent_Identity=35, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24647201, Length=155, Percent_Identity=32.258064516129, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24647195, Length=163, Percent_Identity=33.1288343558282, Blast_Score=73, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24647197, Length=163, Percent_Identity=33.1288343558282, Blast_Score=73, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24647199, Length=154, Percent_Identity=30.5194805194805, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 16346; Mature: 16346

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.3 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
10.5 %Cys+Met (Translated Protein)
5.3 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
10.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHLTVNGREMSLDVDPDTPLLWVLRDELRLTGTKFGCGVAQCGACTVMLDGMPRRSCVT
CEEEEECCCEEEEECCCCCCEEEEEECCCEECCCCCCCCCCCCCEEEEEECCCCCCHHCC
PVGMIENASVTTIEGMEGPEISAVQAAWAASDVPQCGWCQSGQVMSATALLRQIPKPTDE
CCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCHH
EIDHAMGGNLCRCATYVRIRQAIHDAARTLEG
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIHLTVNGREMSLDVDPDTPLLWVLRDELRLTGTKFGCGVAQCGACTVMLDGMPRRSCVT
CEEEEECCCEEEEECCCCCCEEEEEECCCEECCCCCCCCCCCCCEEEEEECCCCCCHHCC
PVGMIENASVTTIEGMEGPEISAVQAAWAASDVPQCGWCQSGQVMSATALLRQIPKPTDE
CCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCHH
EIDHAMGGNLCRCATYVRIRQAIHDAARTLEG
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]