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The map label for this gene is hhoB [H]

Identifier: 77465143

GI number: 77465143

Start: 174755

End: 175969

Strand: Direct

Name: hhoB [H]

Synonym: RSP_3130

Alternate gene names: 77465143

Gene position: 174755-175969 (Clockwise)

Preceding gene: 77465142

Following gene: 77465144

Centisome position: 18.53

GC content: 72.1

Gene sequence:

>1215_bases
ATGATGAGACTTCTCTGCGCGCTTGTCGGATTGCTCTGGGCCGCGGCCGCCGCGGCACAGGATTTCAGCGCCGTCGCCCG
GCTGACCGACGCCTCGGTGGGCCGGATCTTCGTGGACCTTCCTCGCGGAATGAGGACCGGCGCCGGCATGGTCTTCGGCC
AGGGCGCCGGGGGCAGGCTGCTGTACCTGACCAATTTCCATGTTGTTCAGAACGGCGGCGACATTGCCGTCTTCTTCAAG
AACGGCGATGCGATCTCGATCTACAGCGGCACGGTCCTTGCCGTCTCGCAGGAGAAGGACCTGGCGGCGCTGAGCCTCGA
CCCCGAGGAGATCGGCACGCCCTCGCCCCCGCCTCTCGCCATCGACACGCGACGGCTCGCGAAAGGCGAGGCCGTGGTGG
CCATCGGCTATCCCGCCGCGGCCGACGCCACCATGGGGCGCGACATGAACATCGCCGCCTTCGAGACCACGCTGACCGGC
GGCAGCGTCAGCCGCGTGCTGAACGGCTCCTGGCGCGGGGCCTCGGCCGAGCTTGAGATCGTCCAGCACACCGCGCCGCT
CAGCCCCGGCAATTCCGGCGGACCGCTGCTCGACCGGTGCGGGCGGGTGATCGGGGTGAACACGATGATTGCGACGGACG
CGGCCGGGATCTACCTCGCCGCCTCGGCCGGCACCATCGCGGACTTTCTGGCCGAGGCCGGGCTTCCGATGCAGACGGCC
GGCGGCAGTTGCGGCGGAGAGCCGGCCTCTCCGGCTGCGGCGCCACCGGCTGCCACGGTGACGGACGGCCGGGTGCCGAT
CTGGATGATCCTCGGCGGAACCGGCGCCGCGCTGGCTTTGGTCATGGCCGCGATGGCGGTTGCGGCCGGCGGCCGGGGTG
GCGAGCCCGCGGCGCCCCGGGTCGCGCTGACGCTGACCATCGCCACGGGCGGATCGCGCCAGCGGTGCGGCATCGGACGG
GCGAGCCTGCAACGCGGCGTCATCCTCGGACGCGGCGGCGCGGCCGAGGTGGCGATCGACAGCCCGCGCGTCAGCCGCGA
GCATCTGCGGCTGACGCTCGAGGGGCGGCGGCTGATGGCGACGGACCTCGGTTCGACCAACGGGACGATGGTCGACGGCA
GGCCGCTGCCGCCGAACCAGCCGCGGCAGGTGGGCGAGGCCACGGTTCTGGTGCTGGGCGGCGAGGTCGAGATCCGGCTG
AGGGCGGGGTCATGA

Upstream 100 bases:

>100_bases
ACCGCCAGTCCATCGCCATGGTGCTCCTGATGCTGCTGATCGCGGGGGCGGCGGTGTCCTATGGCGTCGTCTCGCGCCAG
CCCGACTGGGTGGCCTACCG

Downstream 100 bases:

>100_bases
AGGATCTGGCGCCCCCCGATCTGGCGGCATCGGACGCGGTCGCCGACATCCGCGATCTTTCGGTCCGGCTGGGAGAGCGG
TTCGAGGTGACGATCGAGCG

Product: putative serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MMRLLCALVGLLWAAAAAAQDFSAVARLTDASVGRIFVDLPRGMRTGAGMVFGQGAGGRLLYLTNFHVVQNGGDIAVFFK
NGDAISIYSGTVLAVSQEKDLAALSLDPEEIGTPSPPPLAIDTRRLAKGEAVVAIGYPAAADATMGRDMNIAAFETTLTG
GSVSRVLNGSWRGASAELEIVQHTAPLSPGNSGGPLLDRCGRVIGVNTMIATDAAGIYLAASAGTIADFLAEAGLPMQTA
GGSCGGEPASPAAAPPAATVTDGRVPIWMILGGTGAALALVMAAMAVAAGGRGGEPAAPRVALTLTIATGGSRQRCGIGR
ASLQRGVILGRGGAAEVAIDSPRVSREHLRLTLEGRRLMATDLGSTNGTMVDGRPLPPNQPRQVGEATVLVLGGEVEIRL
RAGS

Sequences:

>Translated_404_residues
MMRLLCALVGLLWAAAAAAQDFSAVARLTDASVGRIFVDLPRGMRTGAGMVFGQGAGGRLLYLTNFHVVQNGGDIAVFFK
NGDAISIYSGTVLAVSQEKDLAALSLDPEEIGTPSPPPLAIDTRRLAKGEAVVAIGYPAAADATMGRDMNIAAFETTLTG
GSVSRVLNGSWRGASAELEIVQHTAPLSPGNSGGPLLDRCGRVIGVNTMIATDAAGIYLAASAGTIADFLAEAGLPMQTA
GGSCGGEPASPAAAPPAATVTDGRVPIWMILGGTGAALALVMAAMAVAAGGRGGEPAAPRVALTLTIATGGSRQRCGIGR
ASLQRGVILGRGGAAEVAIDSPRVSREHLRLTLEGRRLMATDLGSTNGTMVDGRPLPPNQPRQVGEATVLVLGGEVEIRL
RAGS
>Mature_404_residues
MMRLLCALVGLLWAAAAAAQDFSAVARLTDASVGRIFVDLPRGMRTGAGMVFGQGAGGRLLYLTNFHVVQNGGDIAVFFK
NGDAISIYSGTVLAVSQEKDLAALSLDPEEIGTPSPPPLAIDTRRLAKGEAVVAIGYPAAADATMGRDMNIAAFETTLTG
GSVSRVLNGSWRGASAELEIVQHTAPLSPGNSGGPLLDRCGRVIGVNTMIATDAAGIYLAASAGTIADFLAEAGLPMQTA
GGSCGGEPASPAAAPPAATVTDGRVPIWMILGGTGAALALVMAAMAVAAGGRGGEPAAPRVALTLTIATGGSRQRCGIGR
ASLQRGVILGRGGAAEVAIDSPRVSREHLRLTLEGRRLMATDLGSTNGTMVDGRPLPPNQPRQVGEATVLVLGGEVEIRL
RAGS

Specific function: A putative protease, its function overlaps that of the related putative proteases HtrA and HhoA [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=205, Percent_Identity=30.7317073170732, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI22129776, Length=197, Percent_Identity=30.4568527918782, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 40864; Mature: 40864

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS50006 FHA_DOMAIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRLLCALVGLLWAAAAAAQDFSAVARLTDASVGRIFVDLPRGMRTGAGMVFGQGAGGRL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEEECCCCCEE
LYLTNFHVVQNGGDIAVFFKNGDAISIYSGTVLAVSQEKDLAALSLDPEEIGTPSPPPLA
EEEEEEEEEECCCCEEEEEECCCEEEEECCEEEEEECCCCEEEEECCHHHCCCCCCCCEE
IDTRRLAKGEAVVAIGYPAAADATMGRDMNIAAFETTLTGGSVSRVLNGSWRGASAELEI
ECHHHCCCCCEEEEECCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHCCCCCCCCCEEEE
VQHTAPLSPGNSGGPLLDRCGRVIGVNTMIATDAAGIYLAASAGTIADFLAEAGLPMQTA
EEEECCCCCCCCCCHHHHHCCCEEECCEEEEECCCCEEEEECCCHHHHHHHHCCCCEECC
GGSCGGEPASPAAAPPAATVTDGRVPIWMILGGTGAALALVMAAMAVAAGGRGGEPAAPR
CCCCCCCCCCCCCCCCCCEEECCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCE
VALTLTIATGGSRQRCGIGRASLQRGVILGRGGAAEVAIDSPRVSREHLRLTLEGRRLMA
EEEEEEEECCCCCCCCCCCHHHHHCCEEEECCCCEEEEECCCCCCCEEEEEEECCCEEEE
TDLGSTNGTMVDGRPLPPNQPRQVGEATVLVLGGEVEIRLRAGS
EECCCCCCEEECCCCCCCCCCCCCCCEEEEEECCEEEEEEECCC
>Mature Secondary Structure
MMRLLCALVGLLWAAAAAAQDFSAVARLTDASVGRIFVDLPRGMRTGAGMVFGQGAGGRL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEEECCCCCEE
LYLTNFHVVQNGGDIAVFFKNGDAISIYSGTVLAVSQEKDLAALSLDPEEIGTPSPPPLA
EEEEEEEEEECCCCEEEEEECCCEEEEECCEEEEEECCCCEEEEECCHHHCCCCCCCCEE
IDTRRLAKGEAVVAIGYPAAADATMGRDMNIAAFETTLTGGSVSRVLNGSWRGASAELEI
ECHHHCCCCCEEEEECCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHCCCCCCCCCEEEE
VQHTAPLSPGNSGGPLLDRCGRVIGVNTMIATDAAGIYLAASAGTIADFLAEAGLPMQTA
EEEECCCCCCCCCCHHHHHCCCEEECCEEEEECCCCEEEEECCCHHHHHHHHCCCCEECC
GGSCGGEPASPAAAPPAATVTDGRVPIWMILGGTGAALALVMAAMAVAAGGRGGEPAAPR
CCCCCCCCCCCCCCCCCCEEECCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCE
VALTLTIATGGSRQRCGIGRASLQRGVILGRGGAAEVAIDSPRVSREHLRLTLEGRRLMA
EEEEEEEECCCCCCCCCCCHHHHHCCEEEECCCCEEEEECCCCCCCEEEEEEECCCEEEE
TDLGSTNGTMVDGRPLPPNQPRQVGEATVLVLGGEVEIRLRAGS
EECCCCCCEEECCCCCCCCCCCCCCCEEEEEECCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]