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The map label for this gene is potA [H]

Identifier: 77465144

GI number: 77465144

Start: 175966

End: 176685

Strand: Direct

Name: potA [H]

Synonym: RSP_3131

Alternate gene names: 77465144

Gene position: 175966-176685 (Clockwise)

Preceding gene: 77465143

Following gene: 77465145

Centisome position: 18.66

GC content: 73.33

Gene sequence:

>720_bases
ATGAAGGATCTGGCGCCCCCCGATCTGGCGGCATCGGACGCGGTCGCCGACATCCGCGATCTTTCGGTCCGGCTGGGAGA
GCGGTTCGAGGTGACGATCGAGCGGCTCTCGGTCGCCCCCGGCGAGGTTCTGGTGCTGGATGCGCCCAGCGGCAGCGGCA
AGAGCACGGTGCTCGGGCTGGTCGCGGGGGCGGTTGCGCCTCAGGCGCGGCCGGTGCGGCATCGGGTGGCGGGGCACGAT
CTGGCCGTGGCGTCGCGCCCGCCGGGGCCGGCGGCGGTGGGCTTCGTGCTCCAGACACATGCGCTGGTGCCCTATCTGAC
CATGGGCGACAACATCGGTCTGCCGTCGCGCATCGCGCGGCTGCGGGTGGCGCCGGACTGGGCACGAGAGGTGGTGGTCT
CGCTCGGCCTTGTCGATCTGATGGACCGCTTTCCGGCGCAGCTATCGGTGGGCCAGCGCCAGCGCGCGGCCGTGGCGCGC
GCGATGCTCGCGCGGCCGCGGCTGCTGCTGCTGGACGAGCCGGTCTCGGCCCTCGACCCCGCCAATGTCCGCGCAGTGGA
GGAGCTGATCCTGCGCCTTGCCGGGGAGGCGGGCTCGGCCGTGCTGCTCGCGGGCCACCAGATCGCGGGAAGCGCCTTTG
CCGCCTGCCGCCGCGTGCGACATCGGGTGGAGGTTGCGGGCGCAGTGACGCGCTCGGTCTTCCGGTCGGAGGCGGTCTGA

Upstream 100 bases:

>100_bases
TCGACGGCAGGCCGCTGCCGCCGAACCAGCCGCGGCAGGTGGGCGAGGCCACGGTTCTGGTGCTGGGCGGCGAGGTCGAG
ATCCGGCTGAGGGCGGGGTC

Downstream 100 bases:

>100_bases
TGCCGCTGCCCCTCGTTCTGGCGCTGCGCGAGCTGCGGCACGACTGGATCTCGGCGCTCTGCTTCGTGGCGGCGCTGGTG
GGCGTGCTGGCGCCCATGCT

Product: ABC transporter ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MKDLAPPDLAASDAVADIRDLSVRLGERFEVTIERLSVAPGEVLVLDAPSGSGKSTVLGLVAGAVAPQARPVRHRVAGHD
LAVASRPPGPAAVGFVLQTHALVPYLTMGDNIGLPSRIARLRVAPDWAREVVVSLGLVDLMDRFPAQLSVGQRQRAAVAR
AMLARPRLLLLDEPVSALDPANVRAVEELILRLAGEAGSAVLLAGHQIAGSAFAACRRVRHRVEVAGAVTRSVFRSEAV

Sequences:

>Translated_239_residues
MKDLAPPDLAASDAVADIRDLSVRLGERFEVTIERLSVAPGEVLVLDAPSGSGKSTVLGLVAGAVAPQARPVRHRVAGHD
LAVASRPPGPAAVGFVLQTHALVPYLTMGDNIGLPSRIARLRVAPDWAREVVVSLGLVDLMDRFPAQLSVGQRQRAAVAR
AMLARPRLLLLDEPVSALDPANVRAVEELILRLAGEAGSAVLLAGHQIAGSAFAACRRVRHRVEVAGAVTRSVFRSEAV
>Mature_239_residues
MKDLAPPDLAASDAVADIRDLSVRLGERFEVTIERLSVAPGEVLVLDAPSGSGKSTVLGLVAGAVAPQARPVRHRVAGHD
LAVASRPPGPAAVGFVLQTHALVPYLTMGDNIGLPSRIARLRVAPDWAREVVVSLGLVDLMDRFPAQLSVGQRQRAAVAR
AMLARPRLLLLDEPVSALDPANVRAVEELILRLAGEAGSAVLLAGHQIAGSAFAACRRVRHRVEVAGAVTRSVFRSEAV

Specific function: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system [H]

COG id: COG3839

COG function: function code G; ABC-type sugar transport systems, ATPase components

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI9955963, Length=163, Percent_Identity=32.5153374233129, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI171184400, Length=193, Percent_Identity=33.160621761658, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1786563, Length=188, Percent_Identity=37.7659574468085, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI87081709, Length=206, Percent_Identity=33.495145631068, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1786253, Length=207, Percent_Identity=33.8164251207729, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1790467, Length=179, Percent_Identity=35.195530726257, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1787029, Length=196, Percent_Identity=33.6734693877551, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1789672, Length=206, Percent_Identity=32.5242718446602, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI87081791, Length=166, Percent_Identity=38.5542168674699, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789873, Length=182, Percent_Identity=37.3626373626374, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI87081834, Length=179, Percent_Identity=33.5195530726257, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788761, Length=159, Percent_Identity=38.3647798742138, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787089, Length=224, Percent_Identity=33.0357142857143, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1787370, Length=174, Percent_Identity=35.0574712643678, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786703, Length=184, Percent_Identity=33.695652173913, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI1788225, Length=188, Percent_Identity=35.6382978723404, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1787712, Length=191, Percent_Identity=31.9371727748691, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1786872, Length=185, Percent_Identity=36.2162162162162, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788450, Length=176, Percent_Identity=33.5227272727273, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1786398, Length=180, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787105, Length=185, Percent_Identity=32.972972972973, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI87082267, Length=146, Percent_Identity=36.986301369863, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787164, Length=189, Percent_Identity=34.3915343915344, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789032, Length=179, Percent_Identity=29.608938547486, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1786698, Length=173, Percent_Identity=31.7919075144509, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1790544, Length=200, Percent_Identity=28.5, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788053, Length=169, Percent_Identity=33.1360946745562, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788165, Length=200, Percent_Identity=31.5, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI48994943, Length=193, Percent_Identity=29.0155440414508, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787500, Length=192, Percent_Identity=30.7291666666667, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1789593, Length=195, Percent_Identity=29.2307692307692, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI145693107, Length=206, Percent_Identity=32.5242718446602, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081782, Length=213, Percent_Identity=26.7605633802817, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1789891, Length=182, Percent_Identity=33.5164835164835, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788897, Length=205, Percent_Identity=30.7317073170732, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790190, Length=190, Percent_Identity=24.2105263157895, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1787758, Length=213, Percent_Identity=28.6384976525822, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1789586, Length=200, Percent_Identity=29, Blast_Score=61, Evalue=5e-11,
Organism=Escherichia coli, GI48994883, Length=219, Percent_Identity=26.4840182648402, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI25146777, Length=181, Percent_Identity=33.1491712707182, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17565586, Length=167, Percent_Identity=26.9461077844311, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71992290, Length=184, Percent_Identity=28.2608695652174, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17541710, Length=203, Percent_Identity=30.5418719211823, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115533592, Length=186, Percent_Identity=31.1827956989247, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6319856, Length=192, Percent_Identity=29.1666666666667, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24666092, Length=208, Percent_Identity=29.8076923076923, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281363262, Length=185, Percent_Identity=31.3513513513514, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24653245, Length=185, Percent_Identity=31.3513513513514, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR008995
- InterPro:   IPR017879
- InterPro:   IPR005893
- InterPro:   IPR013611 [H]

Pfam domain/function: PF00005 ABC_tran; PF08402 TOBE_2 [H]

EC number: =3.6.3.31 [H]

Molecular weight: Translated: 25129; Mature: 25129

Theoretical pI: Translated: 10.67; Mature: 10.67

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDLAPPDLAASDAVADIRDLSVRLGERFEVTIERLSVAPGEVLVLDAPSGSGKSTVLGL
CCCCCCCCCCCHHHHHHHHHHHHHHCCHHHEEHHHHHCCCCCEEEEECCCCCCCHHHHHH
VAGAVAPQARPVRHRVAGHDLAVASRPPGPAAVGFVLQTHALVPYLTMGDNIGLPSRIAR
HHHHCCCCCCHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHCEEECCCCCCCHHHHHH
LRVAPDWAREVVVSLGLVDLMDRFPAQLSVGQRQRAAVARAMLARPRLLLLDEPVSALDP
EECCCHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHCCCEEEEECCHHHCCC
ANVRAVEELILRLAGEAGSAVLLAGHQIAGSAFAACRRVRHRVEVAGAVTRSVFRSEAV
CHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKDLAPPDLAASDAVADIRDLSVRLGERFEVTIERLSVAPGEVLVLDAPSGSGKSTVLGL
CCCCCCCCCCCHHHHHHHHHHHHHHCCHHHEEHHHHHCCCCCEEEEECCCCCCCHHHHHH
VAGAVAPQARPVRHRVAGHDLAVASRPPGPAAVGFVLQTHALVPYLTMGDNIGLPSRIAR
HHHHCCCCCCHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHCEEECCCCCCCHHHHHH
LRVAPDWAREVVVSLGLVDLMDRFPAQLSVGQRQRAAVARAMLARPRLLLLDEPVSALDP
EECCCHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHCCCEEEEECCHHHCCC
ANVRAVEELILRLAGEAGSAVLLAGHQIAGSAFAACRRVRHRVEVAGAVTRSVFRSEAV
CHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]