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The map label for this gene is qseC [H]

Identifier: 77465101

GI number: 77465101

Start: 132121

End: 133437

Strand: Reverse

Name: qseC [H]

Synonym: RSP_3086

Alternate gene names: 77465101

Gene position: 133437-132121 (Counterclockwise)

Preceding gene: 77465102

Following gene: 77465098

Centisome position: 14.15

GC content: 74.34

Gene sequence:

>1317_bases
ATGAGCCGACCGCGCAGCCTGCGGCGCGAGCTCGCGCTGGGGCTGTCGGGCGCGATCGTCCTGCTCTGGACGGTGGCCAC
CCTGTCGGCCGCCTATGTGGTGCGCGAGGAGATGGGCGAGACCTTCGACAGTGCGCTTCAGGAGACGGCCGAGCGTCTGC
TGCCGCTTGCGCTGTCGGACGGGACCGACGACACGGCCCCGGTGCCGCGCCGGATCGCGCGCGCGGGCGAGCATGGCGAA
AACCTGACCTGGGTGGTGCGGGATGCGGAAGGGACGGTGCGGCTCTGGTCGCCCGACGCCCGTGCCGAGACCTTCGCCCA
GCCCGTGCCGGCCGGCTTCTCCACCAGCGGGCGTCACCGCTTCTACGCGGTCTCGGATCTCAGCGGACGCTGGACGCTCT
CGATCGCCGAGCCGCTCTCGAACCGGCGCGAGGCGGTGCGCGAGACGCTGGTGGCCTTCGTGGCCCCGATGCTGCTCCTG
CTGCCGCTGATCCTGGCGCTGGTGGTTTGGCGCACGCGGGCGGCTCTCGCGCGGCTGGGCGATCTCTCGCGCGAGGTGCA
GGGGCGCGACGAGACCGACCTCAGACCTCTGGCCACGCAGGGACTGCAGGCCGAACTTCTGCCGCTCCGCGACGCGGTCG
ACCGGCTGATGGCCCGGCTCGGGCGCGCCATCGCCGCCGAGCGCGGCTTCACCGCCAATGCCGCGCATGAGCTTCGCACG
CCCATGGCCGCGGCGCTGGCTCAGGCCCAGCGGCTGATCGTCGAGGCGCCCGAGGCGCTGCGGCCCCGCGCAGAGCGCCT
CGAGCAGGAGCTGAAGCGGCTCGCGCGGCTGGCGGCCAAGCTCCTCGAACTGTCGCGCGCCGAGGGCGCCGCGGTTCTGG
CGGAGACGCCGCAGGATCTGGCGCCGATCCTCGAGATCGTGGTCGACGATGCCCGTCACGGGCCGGAGGGCCTGCGGTTG
CGCGACGAGATCGGCGCGCTCGAGGCCCGGATGGATCCCGACGCCTTCGCCATCCTCGCGCGGAACCTGATCGAGAATGC
GCTGCGGCACGGCGAGGGCGCGGTCGAGGTGACGCTGGGAGCGGAGGGGCTGCGGGTGACGAACGGCGGGCCGGCGCTGG
CGCCGGACCTGCTCGCGCGCATCCCGCAGCGCTTTGCCCGGGGCAGCAGCACGCGGGAAGGCTCGGGGCTGGGCCTCGCC
ATCGCCGCGGGCATCGCCCGGGGCGCGGGCTGGCGCCTCGCGCTGACCTCTCCGATCCCCGGCCGTCCCGACGGCTTCGA
GGCGCGTGCGATCCCGCCTCAGCCGAGGATCGCGTAG

Upstream 100 bases:

>100_bases
AAAGCAACACGATCGAGGTCTATGTCAGCCGCCTGCGCAAGAAGCTCGGGCGCGACCGGATCGAGACGCGGCGCGGCATG
GGCTACCGGCTGGTGCGGGA

Downstream 100 bases:

>100_bases
GCGACGAAGGCCACGTTCGCCAGAATGAGGCAGAGAACGGCGAGCGAGCCCAGATCCTTGGCGTCGCGCGCGAATTCCGC
CCAGCCGGGCGCCAGGTGAT

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 437

Protein sequence:

>438_residues
MSRPRSLRRELALGLSGAIVLLWTVATLSAAYVVREEMGETFDSALQETAERLLPLALSDGTDDTAPVPRRIARAGEHGE
NLTWVVRDAEGTVRLWSPDARAETFAQPVPAGFSTSGRHRFYAVSDLSGRWTLSIAEPLSNRREAVRETLVAFVAPMLLL
LPLILALVVWRTRAALARLGDLSREVQGRDETDLRPLATQGLQAELLPLRDAVDRLMARLGRAIAAERGFTANAAHELRT
PMAAALAQAQRLIVEAPEALRPRAERLEQELKRLARLAAKLLELSRAEGAAVLAETPQDLAPILEIVVDDARHGPEGLRL
RDEIGALEARMDPDAFAILARNLIENALRHGEGAVEVTLGAEGLRVTNGGPALAPDLLARIPQRFARGSSTREGSGLGLA
IAAGIARGAGWRLALTSPIPGRPDGFEARAIPPQPRIA

Sequences:

>Translated_438_residues
MSRPRSLRRELALGLSGAIVLLWTVATLSAAYVVREEMGETFDSALQETAERLLPLALSDGTDDTAPVPRRIARAGEHGE
NLTWVVRDAEGTVRLWSPDARAETFAQPVPAGFSTSGRHRFYAVSDLSGRWTLSIAEPLSNRREAVRETLVAFVAPMLLL
LPLILALVVWRTRAALARLGDLSREVQGRDETDLRPLATQGLQAELLPLRDAVDRLMARLGRAIAAERGFTANAAHELRT
PMAAALAQAQRLIVEAPEALRPRAERLEQELKRLARLAAKLLELSRAEGAAVLAETPQDLAPILEIVVDDARHGPEGLRL
RDEIGALEARMDPDAFAILARNLIENALRHGEGAVEVTLGAEGLRVTNGGPALAPDLLARIPQRFARGSSTREGSGLGLA
IAAGIARGAGWRLALTSPIPGRPDGFEARAIPPQPRIA
>Mature_437_residues
SRPRSLRRELALGLSGAIVLLWTVATLSAAYVVREEMGETFDSALQETAERLLPLALSDGTDDTAPVPRRIARAGEHGEN
LTWVVRDAEGTVRLWSPDARAETFAQPVPAGFSTSGRHRFYAVSDLSGRWTLSIAEPLSNRREAVRETLVAFVAPMLLLL
PLILALVVWRTRAALARLGDLSREVQGRDETDLRPLATQGLQAELLPLRDAVDRLMARLGRAIAAERGFTANAAHELRTP
MAAALAQAQRLIVEAPEALRPRAERLEQELKRLARLAAKLLELSRAEGAAVLAETPQDLAPILEIVVDDARHGPEGLRLR
DEIGALEARMDPDAFAILARNLIENALRHGEGAVEVTLGAEGLRVTNGGPALAPDLLARIPQRFARGSSTREGSGLGLAI
AAGIARGAGWRLALTSPIPGRPDGFEARAIPPQPRIA

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=450, Percent_Identity=28.4444444444444, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1790551, Length=276, Percent_Identity=25, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1786783, Length=307, Percent_Identity=27.0358306188925, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788393, Length=245, Percent_Identity=29.7959183673469, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786600, Length=270, Percent_Identity=27.7777777777778, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1790346, Length=226, Percent_Identity=27.4336283185841, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788279, Length=307, Percent_Identity=25.7328990228013, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 47223; Mature: 47092

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRPRSLRRELALGLSGAIVLLWTVATLSAAYVVREEMGETFDSALQETAERLLPLALSD
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCC
GTDDTAPVPRRIARAGEHGENLTWVVRDAEGTVRLWSPDARAETFAQPVPAGFSTSGRHR
CCCCCCHHHHHHHHCCCCCCCCEEEEECCCCEEEEECCCHHHHHHHCCCCCCCCCCCCEE
FYAVSDLSGRWTLSIAEPLSNRREAVRETLVAFVAPMLLLLPLILALVVWRTRAALARLG
EEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLSREVQGRDETDLRPLATQGLQAELLPLRDAVDRLMARLGRAIAAERGFTANAAHELRT
HHHHHHCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
PMAAALAQAQRLIVEAPEALRPRAERLEQELKRLARLAAKLLELSRAEGAAVLAETPQDL
HHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHH
APILEIVVDDARHGPEGLRLRDEIGALEARMDPDAFAILARNLIENALRHGEGAVEVTLG
HHHHHHHHHHCCCCCCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEC
AEGLRVTNGGPALAPDLLARIPQRFARGSSTREGSGLGLAIAAGIARGAGWRLALTSPIP
CCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCC
GRPDGFEARAIPPQPRIA
CCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SRPRSLRRELALGLSGAIVLLWTVATLSAAYVVREEMGETFDSALQETAERLLPLALSD
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCC
GTDDTAPVPRRIARAGEHGENLTWVVRDAEGTVRLWSPDARAETFAQPVPAGFSTSGRHR
CCCCCCHHHHHHHHCCCCCCCCEEEEECCCCEEEEECCCHHHHHHHCCCCCCCCCCCCEE
FYAVSDLSGRWTLSIAEPLSNRREAVRETLVAFVAPMLLLLPLILALVVWRTRAALARLG
EEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLSREVQGRDETDLRPLATQGLQAELLPLRDAVDRLMARLGRAIAAERGFTANAAHELRT
HHHHHHCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
PMAAALAQAQRLIVEAPEALRPRAERLEQELKRLARLAAKLLELSRAEGAAVLAETPQDL
HHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHH
APILEIVVDDARHGPEGLRLRDEIGALEARMDPDAFAILARNLIENALRHGEGAVEVTLG
HHHHHHHHHHCCCCCCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEC
AEGLRVTNGGPALAPDLLARIPQRFARGSSTREGSGLGLAIAAGIARGAGWRLALTSPIP
CCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCC
GRPDGFEARAIPPQPRIA
CCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]