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The map label for this gene is ttuD [H]

Identifier: 77465084

GI number: 77465084

Start: 110019

End: 111290

Strand: Direct

Name: ttuD [H]

Synonym: RSP_3071

Alternate gene names: 77465084

Gene position: 110019-111290 (Clockwise)

Preceding gene: 77465082

Following gene: 77465087

Centisome position: 11.67

GC content: 75.08

Gene sequence:

>1272_bases
ATGACGGAGTGGACGGACGCCTCGGCCGCGGAATTCCTGCGCCATCTCTTCACAGAGGCGGTGGAGGCCTCGAAGCCCGA
GGCGCGGATCGCGCCCCTGCTGCCGCCGCCGCCCGCGGGCCGGATCCTCGTTCTCGGCGCGGGCAAGGCTGCCGCGGGCA
TGGCGCGGGCGGTCGAGGCCCATTATGCCGATGCGCCGCGCCTCTCGGGCCTCGTCATCACCCGCCACGGGCAGGGCGAG
GCCGCTCCGGGCCGGATCGCAGTGCGTGAGGCAGCCCATCCGGTCCCGGACGAAGCCGGCATCGCCGCCACGGAAGAGCT
TCTGGCCCTGACTCAGGGGCTCGGGCCCGAGGATCTGGTGATCGCGCTGATCTCGGGCGGCGCCTCGTCGCTGATGGTGG
CGCCGCTCGCGGGCCTCACGCTCGCGGACAAGGTGGAGCTCAACCGGGCGCTTCTCGCCTCGGGCGCCACGATCTCGGAG
ATGAACTGCCTGCGGCGGCACCTGAGCCGCGTGAAGGGCGGCCGCCTCGCCGCGGCCTGCGCCCCGGCGCGGGTGCTGGC
GCTCCTCGTCTCGGACGTGCCGGGCGACGATCCGTCGGTGATCGCCTCGGGGCCCTGCCACGGCGATGCCACCACCGTCG
CCGATGCGCAGGCGGTGCTCGGGCGCCTCGGCCTCGATCTGCCCCGGATCGCGGCCGCGCTGGCGCGGCCCGAGGCCGAG
AGCGTGAAGCCCGGCGATCCGCGGCTCGCGCGCGTCGAGAGCCACATCGTCTGCTCGCCGCAGATGGCGCTGGAGGCGGC
GGCCGAGGCGGCACGGGCGGCGGGAGTTGCGGCCCATATCCTCGGCGATGCGCTCGAAGGCGATGCGCGCGAGGCCGGGC
GGCTGATGGCGGGGATCGCGCGGCAGGTGGTGCTGCGCGACCAGCCCTTCGCGCGGCCCTGCCTGCTTCTGTCGGGCGGC
GAGACCACCGTCTCGATCCGCGGCCCGGCCGGCGTGGGCGGGCGCAATGTCGAGTTCCTGCTGGCCTATCTGCTGGCCGC
GCGCGATCTGCCGGGCTGGGCGCTCGCCGCGGACACGGACGGGGTGGATGGTGGCGCCGAGGTGGCGGGTGCGGTGGGCG
GGGCGGCCGTGCTTCAGGCTGCGGGCCGCGACCCGGCCGAGGCGCTGGCCGGACACGATGCCCACAGCTTCTTCGCCGCC
GCCGGTGCGCAGGTGGTGACCGGCCCGACCGGCACCAATGTCAACGATTTCCGGGCGATCCTTCTGCCGTGA

Upstream 100 bases:

>100_bases
GGAAGCTGGAAAGGTCAGGCGATGGCAGGATGGGGGCAGGCGCCTCCGCCGGGACGCGCCGGCGGTCCTGCCCCGATTGC
GGCCGCGGAGGGAGACCGGC

Downstream 100 bases:

>100_bases
CGGCCCGCTCGCGGAACACCGCATGCTCGCCCAGATCGACCGTCGCTTCGCCCGCGAGGAGCTGCCGGTAGAAGTCCTCC
AGCGTCTCGGTGCCGAAGGA

Product: putative hydroxypyruvate reductase/glycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MTEWTDASAAEFLRHLFTEAVEASKPEARIAPLLPPPPAGRILVLGAGKAAAGMARAVEAHYADAPRLSGLVITRHGQGE
AAPGRIAVREAAHPVPDEAGIAATEELLALTQGLGPEDLVIALISGGASSLMVAPLAGLTLADKVELNRALLASGATISE
MNCLRRHLSRVKGGRLAAACAPARVLALLVSDVPGDDPSVIASGPCHGDATTVADAQAVLGRLGLDLPRIAAALARPEAE
SVKPGDPRLARVESHIVCSPQMALEAAAEAARAAGVAAHILGDALEGDAREAGRLMAGIARQVVLRDQPFARPCLLLSGG
ETTVSIRGPAGVGGRNVEFLLAYLLAARDLPGWALAADTDGVDGGAEVAGAVGGAAVLQAAGRDPAEALAGHDAHSFFAA
AGAQVVTGPTGTNVNDFRAILLP

Sequences:

>Translated_423_residues
MTEWTDASAAEFLRHLFTEAVEASKPEARIAPLLPPPPAGRILVLGAGKAAAGMARAVEAHYADAPRLSGLVITRHGQGE
AAPGRIAVREAAHPVPDEAGIAATEELLALTQGLGPEDLVIALISGGASSLMVAPLAGLTLADKVELNRALLASGATISE
MNCLRRHLSRVKGGRLAAACAPARVLALLVSDVPGDDPSVIASGPCHGDATTVADAQAVLGRLGLDLPRIAAALARPEAE
SVKPGDPRLARVESHIVCSPQMALEAAAEAARAAGVAAHILGDALEGDAREAGRLMAGIARQVVLRDQPFARPCLLLSGG
ETTVSIRGPAGVGGRNVEFLLAYLLAARDLPGWALAADTDGVDGGAEVAGAVGGAAVLQAAGRDPAEALAGHDAHSFFAA
AGAQVVTGPTGTNVNDFRAILLP
>Mature_422_residues
TEWTDASAAEFLRHLFTEAVEASKPEARIAPLLPPPPAGRILVLGAGKAAAGMARAVEAHYADAPRLSGLVITRHGQGEA
APGRIAVREAAHPVPDEAGIAATEELLALTQGLGPEDLVIALISGGASSLMVAPLAGLTLADKVELNRALLASGATISEM
NCLRRHLSRVKGGRLAAACAPARVLALLVSDVPGDDPSVIASGPCHGDATTVADAQAVLGRLGLDLPRIAAALARPEAES
VKPGDPRLARVESHIVCSPQMALEAAAEAARAAGVAAHILGDALEGDAREAGRLMAGIARQVVLRDQPFARPCLLLSGGE
TTVSIRGPAGVGGRNVEFLLAYLLAARDLPGWALAADTDGVDGGAEVAGAVGGAAVLQAAGRDPAEALAGHDAHSFFAAA
GAQVVTGPTGTNVNDFRAILLP

Specific function: Degrades an unidentified toxic product from the first step of tartrate degradation [H]

COG id: COG2379

COG function: function code G; Putative glycerate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI31543063, Length=489, Percent_Identity=34.9693251533742, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI193205461, Length=412, Percent_Identity=32.0388349514563, Blast_Score=166, Evalue=3e-41,
Organism=Drosophila melanogaster, GI19920578, Length=490, Percent_Identity=29.3877551020408, Blast_Score=132, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007835 [H]

Pfam domain/function: PF05161 MOFRL [H]

EC number: =1.1.1.81 [H]

Molecular weight: Translated: 42670; Mature: 42539

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEWTDASAAEFLRHLFTEAVEASKPEARIAPLLPPPPAGRILVLGAGKAAAGMARAVEA
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHH
HYADAPRLSGLVITRHGQGEAAPGRIAVREAAHPVPDEAGIAATEELLALTQGLGPEDLV
HCCCCCCCCCEEEEECCCCCCCCCCEEEHHCCCCCCCCCCCHHHHHHHHHHHCCCCHHEE
IALISGGASSLMVAPLAGLTLADKVELNRALLASGATISEMNCLRRHLSRVKGGRLAAAC
EEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEHHH
APARVLALLVSDVPGDDPSVIASGPCHGDATTVADAQAVLGRLGLDLPRIAAALARPEAE
HHHHHHHHHHHCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
SVKPGDPRLARVESHIVCSPQMALEAAAEAARAAGVAAHILGDALEGDAREAGRLMAGIA
CCCCCCCHHHHHHHHEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
RQVVLRDQPFARPCLLLSGGETTVSIRGPAGVGGRNVEFLLAYLLAARDLPGWALAADTD
HHHHHCCCCCCCCEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCC
GVDGGAEVAGAVGGAAVLQAAGRDPAEALAGHDAHSFFAAAGAQVVTGPTGTNVNDFRAI
CCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHCCCEEEECCCCCCCCCCEEE
LLP
ECC
>Mature Secondary Structure 
TEWTDASAAEFLRHLFTEAVEASKPEARIAPLLPPPPAGRILVLGAGKAAAGMARAVEA
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHH
HYADAPRLSGLVITRHGQGEAAPGRIAVREAAHPVPDEAGIAATEELLALTQGLGPEDLV
HCCCCCCCCCEEEEECCCCCCCCCCEEEHHCCCCCCCCCCCHHHHHHHHHHHCCCCHHEE
IALISGGASSLMVAPLAGLTLADKVELNRALLASGATISEMNCLRRHLSRVKGGRLAAAC
EEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEHHH
APARVLALLVSDVPGDDPSVIASGPCHGDATTVADAQAVLGRLGLDLPRIAAALARPEAE
HHHHHHHHHHHCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
SVKPGDPRLARVESHIVCSPQMALEAAAEAARAAGVAAHILGDALEGDAREAGRLMAGIA
CCCCCCCHHHHHHHHEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
RQVVLRDQPFARPCLLLSGGETTVSIRGPAGVGGRNVEFLLAYLLAARDLPGWALAADTD
HHHHHCCCCCCCCEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCC
GVDGGAEVAGAVGGAAVLQAAGRDPAEALAGHDAHSFFAAAGAQVVTGPTGTNVNDFRAI
CCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHCCCEEEECCCCCCCCCCEEE
LLP
ECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]