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The map label for this gene is mhpR [H]

Identifier: 77465038

GI number: 77465038

Start: 55582

End: 56418

Strand: Reverse

Name: mhpR [H]

Synonym: RSP_3024

Alternate gene names: 77465038

Gene position: 56418-55582 (Counterclockwise)

Preceding gene: 77465039

Following gene: 77465036

Centisome position: 5.98

GC content: 66.91

Gene sequence:

>837_bases
ATGAGTCCGGAGCCTAATGGTGACGCAGTATCCATCATACTCGAAACCGAAGGCCCCATGACCGCTGCTCCCAAGACCGT
CCGTTCTGTCGAGCGGACCCTGCAGATCCTCGAACTGATGAACCGGGCCGCTGTCGTGCGGGTCCAGTATCTCGCGGAAC
AGATAGGGCTGCCCGCACCGACCGTCGTACGCCTGCTCGAGACGCTGGTGGCCGCCGGCTATGTGCGCAAGATCGGGCGG
CAGGCGGGCTATTGCGTGACCGAGAAGGTCGCGGCGCTCGGCGCGGGGCATCACGGTCTGCCGCAGGTCTTCGATGTGGC
CCGCGAGGCGGCCGAGGACCTCACGCGGCGCACGCTCTGGCCCACGGCGCTGGCGACGCTCGACGTGGATGCGCTGGTGA
TCCGCTTCAGCACGATACCGATGAGCCCGCTTTCGCATTACCAATCGACGATCAATCGCCGCATGACCCTGCTCGACTAT
GCCCATGGCCGCGCCTATCTCGGCTTCTGCCCGACGGAAGAGCGACAGCATCTCGTGGCCCTGCTTCAGCAGACGGCCGG
CTCGGTCGAAGAGGCCAGGGCCATCGGAGAGCGGGCCCAGTCCGTCGTGGCTCTGACGCGGGCCAGCGGCTTCGGCGAGC
GCACGGGCAACATTCAGCCGGAGACCCATTCCCTCGCCCTGCCCCTGCGGATGGGCGCGAAACTCGTGGGCACGCTGGGC
ATCACCTATTTCGCCAAGGCAAAGGTCGATGTCTCTGCCCTGAAGTCAGACCTGCGCGCTGCGGCGGAGGCCTGCACGAG
CGGGACGGCCTATCGCGCGCCCGCCTCCAGCGGATAG

Upstream 100 bases:

>100_bases
GCCTCACGGGCTGGAGGCGCGTCGCCACCGATACGACATGTGCGCCCGGACAGTCCTCGGTCGCCCCGCCGCAACCGTCA
TGTTCTGGCTTTGACGATCG

Downstream 100 bases:

>100_bases
ACGGTCCGGGCACGGTCATCGTCCCTGCCCGAGGCAAGGATGCGCGGCTTTGCGGTGCGCACATGATCGAGATAGGCCCG
GGCGGAGGCTGCAACCGCGG

Product: DNA-binding transcriptional activator MhpR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MSPEPNGDAVSIILETEGPMTAAPKTVRSVERTLQILELMNRAAVVRVQYLAEQIGLPAPTVVRLLETLVAAGYVRKIGR
QAGYCVTEKVAALGAGHHGLPQVFDVAREAAEDLTRRTLWPTALATLDVDALVIRFSTIPMSPLSHYQSTINRRMTLLDY
AHGRAYLGFCPTEERQHLVALLQQTAGSVEEARAIGERAQSVVALTRASGFGERTGNIQPETHSLALPLRMGAKLVGTLG
ITYFAKAKVDVSALKSDLRAAAEACTSGTAYRAPASSG

Sequences:

>Translated_278_residues
MSPEPNGDAVSIILETEGPMTAAPKTVRSVERTLQILELMNRAAVVRVQYLAEQIGLPAPTVVRLLETLVAAGYVRKIGR
QAGYCVTEKVAALGAGHHGLPQVFDVAREAAEDLTRRTLWPTALATLDVDALVIRFSTIPMSPLSHYQSTINRRMTLLDY
AHGRAYLGFCPTEERQHLVALLQQTAGSVEEARAIGERAQSVVALTRASGFGERTGNIQPETHSLALPLRMGAKLVGTLG
ITYFAKAKVDVSALKSDLRAAAEACTSGTAYRAPASSG
>Mature_277_residues
SPEPNGDAVSIILETEGPMTAAPKTVRSVERTLQILELMNRAAVVRVQYLAEQIGLPAPTVVRLLETLVAAGYVRKIGRQ
AGYCVTEKVAALGAGHHGLPQVFDVAREAAEDLTRRTLWPTALATLDVDALVIRFSTIPMSPLSHYQSTINRRMTLLDYA
HGRAYLGFCPTEERQHLVALLQQTAGSVEEARAIGERAQSVVALTRASGFGERTGNIQPETHSLALPLRMGAKLVGTLGI
TYFAKAKVDVSALKSDLRAAAEACTSGTAYRAPASSG

Specific function: Activator of the mhpRABCDEF operon coding for components of the 3-hydroxyphenylpropionate degradation pathway [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI145693096, Length=202, Percent_Identity=35.1485148514851, Blast_Score=117, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29762; Mature: 29630

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPEPNGDAVSIILETEGPMTAAPKTVRSVERTLQILELMNRAAVVRVQYLAEQIGLPAP
CCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
TVVRLLETLVAAGYVRKIGRQAGYCVTEKVAALGAGHHGLPQVFDVAREAAEDLTRRTLW
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
PTALATLDVDALVIRFSTIPMSPLSHYQSTINRRMTLLDYAHGRAYLGFCPTEERQHLVA
HHHHHHHHHHHHHEEHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHH
LLQQTAGSVEEARAIGERAQSVVALTRASGFGERTGNIQPETHSLALPLRMGAKLVGTLG
HHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHEEEHHHHHHHHHHHHH
ITYFAKAKVDVSALKSDLRAAAEACTSGTAYRAPASSG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SPEPNGDAVSIILETEGPMTAAPKTVRSVERTLQILELMNRAAVVRVQYLAEQIGLPAP
CCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
TVVRLLETLVAAGYVRKIGRQAGYCVTEKVAALGAGHHGLPQVFDVAREAAEDLTRRTLW
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
PTALATLDVDALVIRFSTIPMSPLSHYQSTINRRMTLLDYAHGRAYLGFCPTEERQHLVA
HHHHHHHHHHHHHEEHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHH
LLQQTAGSVEEARAIGERAQSVVALTRASGFGERTGNIQPETHSLALPLRMGAKLVGTLG
HHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHEEEHHHHHHHHHHHHH
ITYFAKAKVDVSALKSDLRAAAEACTSGTAYRAPASSG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]