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The map label for this gene is xpt [H]

Identifier: 77461741

GI number: 77461741

Start: 6189628

End: 6190200

Strand: Direct

Name: xpt [H]

Synonym: Pfl01_5520

Alternate gene names: 77461741

Gene position: 6189628-6190200 (Clockwise)

Preceding gene: 77461740

Following gene: 77461748

Centisome position: 96.14

GC content: 60.38

Gene sequence:

>573_bases
ATGGAAGCATTGCACCAGAAAATCCGCGAACAAGGCATTGTGCTTTCCGACCAGGTCCTGAAGGTCGACGCCTTCCTGAA
CCACCAGATCGACCCGGCCCTGATGAAGCTGATCGGCGACGAATTCGCCACGCTGTTCAAGGATTCGGGCATCACCAAGA
TTGTCACCATCGAAGCCTCGGGCATCGCGCCGGCGATCATGACCGGTCTGAACCTCGGCGTGCCGGTGATCTTCGCCCGC
AAGCAACAGTCCCTGACCCTGACTGAAAACCTGCTGTCGGCGACCGTTTACTCGTTCACCAAGAAAACCGAAAGCACCGT
GGCCATCTCCCCTCGCCACCTGACCAGCAGCGACCGTGTGCTGATCATCGACGACTTCCTGGCCAACGGTAAGGCCTCCC
AGGCGCTGATCTCGATCATCAAGCAGGCCGGCGCCACCGTCGCGGGCCTGGGCATCGTGATCGAGAAGTCGTTCCAGGGC
GGCCGTGCGGAGCTGGATTCGCAGGGTTACCGCGTCGAGTCGCTGGCTCGCGTGAAGTCGCTGAAGGATGGCGTGGTTAC
CTTCATCGAGTAA

Upstream 100 bases:

>100_bases
CAACAGCGCACTGGCTGATATACGCGCGATGTTAAAGCGCTAGAATTGACCACTTTTTACTAGACCTTCGGCGCACAAAG
CGCCAAATGAGGACAGCTTC

Downstream 100 bases:

>100_bases
CCCGGCTTCATCGCATTATCCCTGTGGGAGCGGGCTTGCTCGCGAAGGCGTTGTGTCAGTCAAAGTATAGGTCGACTGAC
ACGGCGTCTTCGCGAGCAAG

Product: xanthine phosphoribosyltransferase

Products: NA

Alternate protein names: XPRTase [H]

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MEALHQKIREQGIVLSDQVLKVDAFLNHQIDPALMKLIGDEFATLFKDSGITKIVTIEASGIAPAIMTGLNLGVPVIFAR
KQQSLTLTENLLSATVYSFTKKTESTVAISPRHLTSSDRVLIIDDFLANGKASQALISIIKQAGATVAGLGIVIEKSFQG
GRAELDSQGYRVESLARVKSLKDGVVTFIE

Sequences:

>Translated_190_residues
MEALHQKIREQGIVLSDQVLKVDAFLNHQIDPALMKLIGDEFATLFKDSGITKIVTIEASGIAPAIMTGLNLGVPVIFAR
KQQSLTLTENLLSATVYSFTKKTESTVAISPRHLTSSDRVLIIDDFLANGKASQALISIIKQAGATVAGLGIVIEKSFQG
GRAELDSQGYRVESLARVKSLKDGVVTFIE
>Mature_190_residues
MEALHQKIREQGIVLSDQVLKVDAFLNHQIDPALMKLIGDEFATLFKDSGITKIVTIEASGIAPAIMTGLNLGVPVIFAR
KQQSLTLTENLLSATVYSFTKKTESTVAISPRHLTSSDRVLIIDDFLANGKASQALISIIKQAGATVAGLGIVIEKSFQG
GRAELDSQGYRVESLARVKSLKDGVVTFIE

Specific function: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis [H]

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XPT subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR010079 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.22 [H]

Molecular weight: Translated: 20454; Mature: 20454

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEALHQKIREQGIVLSDQVLKVDAFLNHQIDPALMKLIGDEFATLFKDSGITKIVTIEAS
CHHHHHHHHHCCCEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECC
GIAPAIMTGLNLGVPVIFARKQQSLTLTENLLSATVYSFTKKTESTVAISPRHLTSSDRV
CCCHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCE
LIIDDFLANGKASQALISIIKQAGATVAGLGIVIEKSFQGGRAELDSQGYRVESLARVKS
EEEECCCCCCCHHHHHHHHHHHHCCCEEEHEEEEEECCCCCCCCCCCCCCHHHHHHHHHH
LKDGVVTFIE
HHCCEEEECC
>Mature Secondary Structure
MEALHQKIREQGIVLSDQVLKVDAFLNHQIDPALMKLIGDEFATLFKDSGITKIVTIEAS
CHHHHHHHHHCCCEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECC
GIAPAIMTGLNLGVPVIFARKQQSLTLTENLLSATVYSFTKKTESTVAISPRHLTSSDRV
CCCHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCE
LIIDDFLANGKASQALISIIKQAGATVAGLGIVIEKSFQGGRAELDSQGYRVESLARVKS
EEEECCCCCCCHHHHHHHHHHHHCCCEEEHEEEEEECCCCCCCCCCCCCCHHHHHHHHHH
LKDGVVTFIE
HHCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA