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The map label for this gene is ygfA [C]

Identifier: 77461659

GI number: 77461659

Start: 6104591

End: 6105196

Strand: Direct

Name: ygfA [C]

Synonym: Pfl01_5438

Alternate gene names: 77461659

Gene position: 6104591-6105196 (Clockwise)

Preceding gene: 77461658

Following gene: 77461661

Centisome position: 94.82

GC content: 63.37

Gene sequence:

>606_bases
ATGACCGAACCCGCGCTGCTGCCCCGTCCTCAACTGCGCCGCCTGCTGCGCAAGGCCCGCCGCTCGCTGACGCGAAGCGA
ACAACGCCAGGCCGCCGAAGGCCTGTACAGGCAACTGGCACAAGACCCGCACTTTCGCCGGGCCAAACACATTTCCCTGT
ACCTGCCCACCGACGGTGAAATCGACCCGCGCCTGTTGCTGCGCGCCGCCCAGCGTCGGGGCAAGAAAACCTACCTGCCG
GTGCTCAGTGCCTGGCCGCGGACCAAAATGGTCTTTCAGCAAATCCGCCCCGGCGAAAAACTAAAACCCAACCGTTTCCG
CATTCTTGAACCGCGCGCCAATCTGGCCCGTCAGCGCAAGGTCTGGGCGCTGGATCTGGTGTTGTTGCCCCTGGTGGGGT
TTGACGATGTCGGCGGACGCCTGGGTATGGGCGGCGGTTTCTACGATCGCAGCCTGGCGTATCTGGCCCGACGACAGAAC
TGGCGCAAGCCGACGCTGCTGGGCCTGGCCCATGAATGTCAGAAAGTCGAACGTCTCGCGCAAGCGAGCTGGGATGTACC
GTTGCAGGGAACGGTGACAGACAAGGCGTGGTATTTCGCAGGATAG

Upstream 100 bases:

>100_bases
GCGGCTCATCCGGGGAGCCTGATTCGAATCCGATGCCGGTGCATGCCGGCATCGGATTTTTTATGCGTACGTTTTCGTCC
CACCCTGCCGAAGCCGAACC

Downstream 100 bases:

>100_bases
ACGCCGCGCGGATCAGCGGCGTCGAAAAGGCAGTGTCAGCGCTTGAAGGCTGTCGACTGTTGTACTTGTTGCGCCACTTC
AATCGGTGCATCGGCCTTGT

Product: 5-formyltetrahydrofolate cyclo-ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MTEPALLPRPQLRRLLRKARRSLTRSEQRQAAEGLYRQLAQDPHFRRAKHISLYLPTDGEIDPRLLLRAAQRRGKKTYLP
VLSAWPRTKMVFQQIRPGEKLKPNRFRILEPRANLARQRKVWALDLVLLPLVGFDDVGGRLGMGGGFYDRSLAYLARRQN
WRKPTLLGLAHECQKVERLAQASWDVPLQGTVTDKAWYFAG

Sequences:

>Translated_201_residues
MTEPALLPRPQLRRLLRKARRSLTRSEQRQAAEGLYRQLAQDPHFRRAKHISLYLPTDGEIDPRLLLRAAQRRGKKTYLP
VLSAWPRTKMVFQQIRPGEKLKPNRFRILEPRANLARQRKVWALDLVLLPLVGFDDVGGRLGMGGGFYDRSLAYLARRQN
WRKPTLLGLAHECQKVERLAQASWDVPLQGTVTDKAWYFAG
>Mature_200_residues
TEPALLPRPQLRRLLRKARRSLTRSEQRQAAEGLYRQLAQDPHFRRAKHISLYLPTDGEIDPRLLLRAAQRRGKKTYLPV
LSAWPRTKMVFQQIRPGEKLKPNRFRILEPRANLARQRKVWALDLVLLPLVGFDDVGGRLGMGGGFYDRSLAYLARRQNW
RKPTLLGLAHECQKVERLAQASWDVPLQGTVTDKAWYFAG

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Escherichia coli, GI1789278, Length=186, Percent_Identity=37.6344086021505, Blast_Score=127, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17510857, Length=191, Percent_Identity=23.5602094240838, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI161077430, Length=190, Percent_Identity=28.4210526315789, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: NA

Molecular weight: Translated: 23273; Mature: 23141

Theoretical pI: Translated: 11.75; Mature: 11.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPALLPRPQLRRLLRKARRSLTRSEQRQAAEGLYRQLAQDPHFRRAKHISLYLPTDGE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCC
IDPRLLLRAAQRRGKKTYLPVLSAWPRTKMVFQQIRPGEKLKPNRFRILEPRANLARQRK
CCHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHCCCCCCCCCCCEEEECCHHHHHHHHH
VWALDLVLLPLVGFDDVGGRLGMGGGFYDRSLAYLARRQNWRKPTLLGLAHECQKVERLA
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
QASWDVPLQGTVTDKAWYFAG
HHCCCCCCCCCCCCCCEEECC
>Mature Secondary Structure 
TEPALLPRPQLRRLLRKARRSLTRSEQRQAAEGLYRQLAQDPHFRRAKHISLYLPTDGE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCC
IDPRLLLRAAQRRGKKTYLPVLSAWPRTKMVFQQIRPGEKLKPNRFRILEPRANLARQRK
CCHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHCCCCCCCCCCCEEEECCHHHHHHHHH
VWALDLVLLPLVGFDDVGGRLGMGGGFYDRSLAYLARRQNWRKPTLLGLAHECQKVERLA
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
QASWDVPLQGTVTDKAWYFAG
HHCCCCCCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]