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The map label for this gene is ubiH [H]

Identifier: 77461654

GI number: 77461654

Start: 6100546

End: 6101733

Strand: Reverse

Name: ubiH [H]

Synonym: Pfl01_5433

Alternate gene names: 77461654

Gene position: 6101733-6100546 (Counterclockwise)

Preceding gene: 77461655

Following gene: 77461653

Centisome position: 94.77

GC content: 65.82

Gene sequence:

>1188_bases
ATGAGTCGGGTCAATCTGGCAATCATCGGTGGCGGTCTGGTCGGCGCCAGTCTGGCGTTGGCCTTGCAGGCCGGGGCCAA
GGCCCGTGGCTGGAAGATCGTGCTGATCGAACCGTTCGCCCCCGGTGACACCTGGCAGCCAAGCTACGACGCGCGTTCTT
CGGCGCTGTCCTTCGGCTCGCGGCAGATTTATCAGCGGCTGGGCGTGTGGCAGGAAATCTCCCGTCGCGCCGAGCCGATC
AAGCAGATTCACGTGTCCGACCGTGGACGCTTTTCCACCGCTCGCCTGTCGGCGATGGAAGAGGGCGTCCCGGCGCTCGG
TTACGTGGTGGAAAACGCCTGGCTCGGCCAGTGCCTGTGGCAGCACCTCGACAAAGACGTGATCAGCTGGCGCTGCCCGG
CGGAAGTCAGCCGCATGGAACCGTTGCCCGACGGCTATCGCCTGACCCTCAATGACGAGACCACGGTCGAGTGCGATCTG
GCGGTGCTCGCCGATGGCGGTCGTTCCGGTCTGCGCGAGCAACTGGGCATCAACGTACGCAAGCGTCCGTATAACCAGAG
CGCGCTGATCGCCAACATCACGCCGAGCGAAGCGCACAACGGCATGGCCTTCGAGCGCTTCACCGACGAAGGTCCGATGG
CGCTGCTGCCGCTGCCGGAAAACCGCTGCGCGCTGGTCTGGACCCGTCTGGGCATGGACGCGCAACGGCTGGCCGACCTG
AGCGAACGAGATTTCCTCAGCGAGCTACAAGGCGTGTTCGGTTACCGTCTTGGCACTCTGAAGCAGGTCGGCGCGCGGCA
TCTGTATCCGCTGTCGCTGGTGGAAGCCGAAGAGCAGGTGCGCTCGCATCTGGCCGTGCTCGGCAACGCCGCCCACAGCT
TGCACCCGATTGCCGGGCAGGGTTTCAACCTGTCCCTGCGCGATGCCGATGCGTTGGCCGCCGCGTTGCTGGCCAGCGAC
AAACCGCTGGGGGATTTTGCGACCTTGCAGGCCTATCGCGAGCGTCAGCGTCTCGATCAGGACCTCACCGTCGGTTTCTC
CGATCAGGTTACGCGCCTGTTCGGCAGCACCCAGCCGCTGGTGTCGCTGGGGCGCAACATCGGCCTGCTCGGCCTCGATC
TGCTGCCGCCGGCCAAACGCTGGTTCGCCCGTCAGGCCATGGGGCTGGGGACGCGGCCGGATGCGTGA

Upstream 100 bases:

>100_bases
TGGTAGTGACCAAGAGCGGTTGTGAAATCCTGACCGGCGGCGTGCCGAAAACCGTCGCCGAGATCGAAGCCCTGATGGCG
CAAGCACGGACCTGCGCGGC

Downstream 100 bases:

>100_bases
GTGGCTGATCAGACGGTTTGGCAAGGCGCGGCTGATGCGCTGGATCATGACGCTCTACCCGCCGTACTTCGGCGCCGGTG
TCCGGGTGCAGCACATCAGC

Product: 2-octaprenyl-6-methoxyphenyl hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MSRVNLAIIGGGLVGASLALALQAGAKARGWKIVLIEPFAPGDTWQPSYDARSSALSFGSRQIYQRLGVWQEISRRAEPI
KQIHVSDRGRFSTARLSAMEEGVPALGYVVENAWLGQCLWQHLDKDVISWRCPAEVSRMEPLPDGYRLTLNDETTVECDL
AVLADGGRSGLREQLGINVRKRPYNQSALIANITPSEAHNGMAFERFTDEGPMALLPLPENRCALVWTRLGMDAQRLADL
SERDFLSELQGVFGYRLGTLKQVGARHLYPLSLVEAEEQVRSHLAVLGNAAHSLHPIAGQGFNLSLRDADALAAALLASD
KPLGDFATLQAYRERQRLDQDLTVGFSDQVTRLFGSTQPLVSLGRNIGLLGLDLLPPAKRWFARQAMGLGTRPDA

Sequences:

>Translated_395_residues
MSRVNLAIIGGGLVGASLALALQAGAKARGWKIVLIEPFAPGDTWQPSYDARSSALSFGSRQIYQRLGVWQEISRRAEPI
KQIHVSDRGRFSTARLSAMEEGVPALGYVVENAWLGQCLWQHLDKDVISWRCPAEVSRMEPLPDGYRLTLNDETTVECDL
AVLADGGRSGLREQLGINVRKRPYNQSALIANITPSEAHNGMAFERFTDEGPMALLPLPENRCALVWTRLGMDAQRLADL
SERDFLSELQGVFGYRLGTLKQVGARHLYPLSLVEAEEQVRSHLAVLGNAAHSLHPIAGQGFNLSLRDADALAAALLASD
KPLGDFATLQAYRERQRLDQDLTVGFSDQVTRLFGSTQPLVSLGRNIGLLGLDLLPPAKRWFARQAMGLGTRPDA
>Mature_394_residues
SRVNLAIIGGGLVGASLALALQAGAKARGWKIVLIEPFAPGDTWQPSYDARSSALSFGSRQIYQRLGVWQEISRRAEPIK
QIHVSDRGRFSTARLSAMEEGVPALGYVVENAWLGQCLWQHLDKDVISWRCPAEVSRMEPLPDGYRLTLNDETTVECDLA
VLADGGRSGLREQLGINVRKRPYNQSALIANITPSEAHNGMAFERFTDEGPMALLPLPENRCALVWTRLGMDAQRLADLS
ERDFLSELQGVFGYRLGTLKQVGARHLYPLSLVEAEEQVRSHLAVLGNAAHSLHPIAGQGFNLSLRDADALAAALLASDK
PLGDFATLQAYRERQRLDQDLTVGFSDQVTRLFGSTQPLVSLGRNIGLLGLDLLPPAKRWFARQAMGLGTRPDA

Specific function: Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=431, Percent_Identity=29.2343387470998, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI32967307, Length=344, Percent_Identity=29.9418604651163, Blast_Score=130, Evalue=3e-30,
Organism=Escherichia coli, GI1789274, Length=389, Percent_Identity=37.7892030848329, Blast_Score=264, Evalue=6e-72,
Organism=Escherichia coli, GI1789273, Length=402, Percent_Identity=34.8258706467662, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1786883, Length=392, Percent_Identity=30.8673469387755, Blast_Score=162, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI25146631, Length=434, Percent_Identity=26.7281105990783, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI19920760, Length=429, Percent_Identity=27.972027972028, Blast_Score=127, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971
- InterPro:   IPR011295 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 43301; Mature: 43170

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRVNLAIIGGGLVGASLALALQAGAKARGWKIVLIEPFAPGDTWQPSYDARSSALSFGS
CCCEEEEEEECHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHH
RQIYQRLGVWQEISRRAEPIKQIHVSDRGRFSTARLSAMEEGVPALGYVVENAWLGQCLW
HHHHHHHCHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
QHLDKDVISWRCPAEVSRMEPLPDGYRLTLNDETTVECDLAVLADGGRSGLREQLGINVR
HHHCHHHHCCCCCHHHHHCCCCCCCCEEEECCCCEEEEEEEEEECCCHHHHHHHHCCCCC
KRPYNQSALIANITPSEAHNGMAFERFTDEGPMALLPLPENRCALVWTRLGMDAQRLADL
CCCCCCCEEEEECCCCCCCCCCEEEEECCCCCEEEEECCCCCEEEEEEHHCCCHHHHHCC
SERDFLSELQGVFGYRLGTLKQVGARHLYPLSLVEAEEQVRSHLAVLGNAAHSLHPIAGQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GFNLSLRDADALAAALLASDKPLGDFATLQAYRERQRLDQDLTVGFSDQVTRLFGSTQPL
CCEEEECCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHCCCCHH
VSLGRNIGLLGLDLLPPAKRWFARQAMGLGTRPDA
HHHCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SRVNLAIIGGGLVGASLALALQAGAKARGWKIVLIEPFAPGDTWQPSYDARSSALSFGS
CCEEEEEEECHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHH
RQIYQRLGVWQEISRRAEPIKQIHVSDRGRFSTARLSAMEEGVPALGYVVENAWLGQCLW
HHHHHHHCHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
QHLDKDVISWRCPAEVSRMEPLPDGYRLTLNDETTVECDLAVLADGGRSGLREQLGINVR
HHHCHHHHCCCCCHHHHHCCCCCCCCEEEECCCCEEEEEEEEEECCCHHHHHHHHCCCCC
KRPYNQSALIANITPSEAHNGMAFERFTDEGPMALLPLPENRCALVWTRLGMDAQRLADL
CCCCCCCEEEEECCCCCCCCCCEEEEECCCCCEEEEECCCCCEEEEEEHHCCCHHHHHCC
SERDFLSELQGVFGYRLGTLKQVGARHLYPLSLVEAEEQVRSHLAVLGNAAHSLHPIAGQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GFNLSLRDADALAAALLASDKPLGDFATLQAYRERQRLDQDLTVGFSDQVTRLFGSTQPL
CCEEEECCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHCCCCHH
VSLGRNIGLLGLDLLPPAKRWFARQAMGLGTRPDA
HHHCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]