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The map label for this gene is visC [H]

Identifier: 77461652

GI number: 77461652

Start: 6098841

End: 6100064

Strand: Reverse

Name: visC [H]

Synonym: Pfl01_5431

Alternate gene names: 77461652

Gene position: 6100064-6098841 (Counterclockwise)

Preceding gene: 77461653

Following gene: 77461651

Centisome position: 94.74

GC content: 66.26

Gene sequence:

>1224_bases
ATGGAAATGCGCGCGGATGTGCTGATTGTCGGAGCCGGAATGGTCGGCAGTGCCCTGGCGCTGGCGTTGCAGGGCAGCGG
GCTGGAAGTCCTGCTGCTCGACGGCAGCCCGTTGAGCGTCAAACCCTTCAAGGGCGACGCACCGTTCGAGCCACGGGTGA
GCGCACTGTCGGCGGCCAGCCAGCGAATCCTCGATCGCCTCGGCGTGTGGGACGGCATCGTCAATCGACGCACCAGCCCT
TACACCGACATGCACGTCTGGGACGGCAGCGGCACCGGGCAGATCCACTTCTCGGCCAGCAGTGTGCACGCCGATGTGCT
TGGGCATATTGTTGAAAACCGCGTGGTCCAGGATGCCTTGCTCGAGCGTCTGCACGATTGCGACCTGGGCCTGCTGGCCA
ACGCGCGGCTGGAGCAGATGCGCCGTTCCGGTGACGACTGGCTGCTGACCCTGGCCGATGGCCGCACCTTGCGCGCGCCG
CTGGTGATCGCGGCGGACGGCGCCAACTCTGCCGTGCGCCGTCTGACCGGTGTCGCCACTCGCGAGTGGGATTACCTGCA
TCACGCCATCGTCACCAGCGTGTGCAGCAGCAAACCGCACCGCATGACCGCGTGGCAGCGTTTCACCGATCACGGGCCTC
TGGCCTTTTTGCCGCTGGAGCGTGACGGTCAGCAGGACTGGTGCTCGATCGTCTGGTCTACCACGCCGAGCGAAGCCGAA
CGGCTGATGGCGCTGGAGGAAGCGGACTTCTGCCGTGAGCTGGAGCGCGCGTTCGAAGGTAGCCTCGGCGAGGTCATCAG
CGCCGACCCGCGCCTGTGTGTGCCGCTGCGTCAGCGTCACGCCAAGCGCTACGTGGCCGAAGGCCTGGCGCTGATCGGTG
ATGCCGCACACACCATTCACCCATTGGCGGGGCAGGGTGTGAACCTGGGTTTCCTCGACGCCGCGGTGCTGGCCGAAGTG
TTGTTGCAGGCCAACGAACGCGGCGAACGCCTAGCTGACGTGAAAGTCCTGAGCCGCTACGAGCGTCGGCGTATGCCGCA
CAACCTGGCACTGATGGCGGCGATGGAAGGCTTCGAGCGGTTGTTCCAGGCTGACCCGCTGCCGCTGCGCTGGCTGCGCA
ACACCGGGCTGAAAATCGTCGAGCAGATGCCCGAGGCCAAGGCGCTGTTCGTGCGTGAAGCATTGGGGCTGACCGGGGAC
TTGCCGGCCCTGGCCAAGGCCTGA

Upstream 100 bases:

>100_bases
GTTGCAGGTCGACATTCATGACGGCGCCGGCAACCTGGTGGCGCGGGTCGGTAAAACCCTTTACGTGCGGCTCAAGCCGC
CAGCGAGACAGGCTTAAAGC

Downstream 100 bases:

>100_bases
CGACTGTCGTGCAACATCTGGTAACTCCTTGAGAAAGTGATCGATTGAGCTGGTAAATGTGAGTCCTTATCATTTGGGCC
ACTTTTCCCGACCGAGAGAC

Product: 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MEMRADVLIVGAGMVGSALALALQGSGLEVLLLDGSPLSVKPFKGDAPFEPRVSALSAASQRILDRLGVWDGIVNRRTSP
YTDMHVWDGSGTGQIHFSASSVHADVLGHIVENRVVQDALLERLHDCDLGLLANARLEQMRRSGDDWLLTLADGRTLRAP
LVIAADGANSAVRRLTGVATREWDYLHHAIVTSVCSSKPHRMTAWQRFTDHGPLAFLPLERDGQQDWCSIVWSTTPSEAE
RLMALEEADFCRELERAFEGSLGEVISADPRLCVPLRQRHAKRYVAEGLALIGDAAHTIHPLAGQGVNLGFLDAAVLAEV
LLQANERGERLADVKVLSRYERRRMPHNLALMAAMEGFERLFQADPLPLRWLRNTGLKIVEQMPEAKALFVREALGLTGD
LPALAKA

Sequences:

>Translated_407_residues
MEMRADVLIVGAGMVGSALALALQGSGLEVLLLDGSPLSVKPFKGDAPFEPRVSALSAASQRILDRLGVWDGIVNRRTSP
YTDMHVWDGSGTGQIHFSASSVHADVLGHIVENRVVQDALLERLHDCDLGLLANARLEQMRRSGDDWLLTLADGRTLRAP
LVIAADGANSAVRRLTGVATREWDYLHHAIVTSVCSSKPHRMTAWQRFTDHGPLAFLPLERDGQQDWCSIVWSTTPSEAE
RLMALEEADFCRELERAFEGSLGEVISADPRLCVPLRQRHAKRYVAEGLALIGDAAHTIHPLAGQGVNLGFLDAAVLAEV
LLQANERGERLADVKVLSRYERRRMPHNLALMAAMEGFERLFQADPLPLRWLRNTGLKIVEQMPEAKALFVREALGLTGD
LPALAKA
>Mature_407_residues
MEMRADVLIVGAGMVGSALALALQGSGLEVLLLDGSPLSVKPFKGDAPFEPRVSALSAASQRILDRLGVWDGIVNRRTSP
YTDMHVWDGSGTGQIHFSASSVHADVLGHIVENRVVQDALLERLHDCDLGLLANARLEQMRRSGDDWLLTLADGRTLRAP
LVIAADGANSAVRRLTGVATREWDYLHHAIVTSVCSSKPHRMTAWQRFTDHGPLAFLPLERDGQQDWCSIVWSTTPSEAE
RLMALEEADFCRELERAFEGSLGEVISADPRLCVPLRQRHAKRYVAEGLALIGDAAHTIHPLAGQGVNLGFLDAAVLAEV
LLQANERGERLADVKVLSRYERRRMPHNLALMAAMEGFERLFQADPLPLRWLRNTGLKIVEQMPEAKALFVREALGLTGD
LPALAKA

Specific function: Not yet known [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=417, Percent_Identity=32.6139088729017, Blast_Score=192, Evalue=6e-49,
Organism=Homo sapiens, GI32967307, Length=346, Percent_Identity=33.2369942196532, Blast_Score=163, Evalue=3e-40,
Organism=Escherichia coli, GI1789273, Length=399, Percent_Identity=45.8646616541353, Blast_Score=310, Evalue=2e-85,
Organism=Escherichia coli, GI1786883, Length=394, Percent_Identity=40.3553299492386, Blast_Score=256, Evalue=1e-69,
Organism=Escherichia coli, GI1789274, Length=395, Percent_Identity=35.4430379746835, Blast_Score=206, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI25146631, Length=433, Percent_Identity=30.4849884526559, Blast_Score=187, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6321694, Length=459, Percent_Identity=26.5795206971678, Blast_Score=137, Evalue=2e-33,
Organism=Drosophila melanogaster, GI19920760, Length=429, Percent_Identity=33.5664335664336, Blast_Score=205, Evalue=5e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 44640; Mature: 44640

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMRADVLIVGAGMVGSALALALQGSGLEVLLLDGSPLSVKPFKGDAPFEPRVSALSAAS
CCCCCCEEEEECCHHHHHHHHEECCCCCEEEEECCCCCEECCCCCCCCCCCHHHHHHHHH
QRILDRLGVWDGIVNRRTSPYTDMHVWDGSGTGQIHFSASSVHADVLGHIVENRVVQDAL
HHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHH
LERLHDCDLGLLANARLEQMRRSGDDWLLTLADGRTLRAPLVIAADGANSAVRRLTGVAT
HHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCCEEECCEEEEECCCHHHHHHHHHHHH
REWDYLHHAIVTSVCSSKPHRMTAWQRFTDHGPLAFLPLERDGQQDWCSIVWSTTPSEAE
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCHHHEEECCCHHHHH
RLMALEEADFCRELERAFEGSLGEVISADPRLCVPLRQRHAKRYVAEGLALIGDAAHTIH
HHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHCCHHHHHC
PLAGQGVNLGFLDAAVLAEVLLQANERGERLADVKVLSRYERRRMPHNLALMAAMEGFER
CCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LFQADPLPLRWLRNTGLKIVEQMPEAKALFVREALGLTGDLPALAKA
HHHCCCCCHHHHHHCCHHHHHHCCCHHHHHHHHHHCCCCCCHHHCCC
>Mature Secondary Structure
MEMRADVLIVGAGMVGSALALALQGSGLEVLLLDGSPLSVKPFKGDAPFEPRVSALSAAS
CCCCCCEEEEECCHHHHHHHHEECCCCCEEEEECCCCCEECCCCCCCCCCCHHHHHHHHH
QRILDRLGVWDGIVNRRTSPYTDMHVWDGSGTGQIHFSASSVHADVLGHIVENRVVQDAL
HHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHH
LERLHDCDLGLLANARLEQMRRSGDDWLLTLADGRTLRAPLVIAADGANSAVRRLTGVAT
HHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCCEEECCEEEEECCCHHHHHHHHHHHH
REWDYLHHAIVTSVCSSKPHRMTAWQRFTDHGPLAFLPLERDGQQDWCSIVWSTTPSEAE
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCHHHEEECCCHHHHH
RLMALEEADFCRELERAFEGSLGEVISADPRLCVPLRQRHAKRYVAEGLALIGDAAHTIH
HHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHCCHHHHHC
PLAGQGVNLGFLDAAVLAEVLLQANERGERLADVKVLSRYERRRMPHNLALMAAMEGFER
CCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LFQADPLPLRWLRNTGLKIVEQMPEAKALFVREALGLTGDLPALAKA
HHHCCCCCHHHHHHCCHHHHHHCCCHHHHHHHHHHCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With NADH2 or NADPH2 as one donor, and incorporation of one atom of oxygen [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]