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The map label for this gene is pgk [H]

Identifier: 77461486

GI number: 77461486

Start: 5924071

End: 5925234

Strand: Reverse

Name: pgk [H]

Synonym: Pfl01_5265

Alternate gene names: 77461486

Gene position: 5925234-5924071 (Counterclockwise)

Preceding gene: 77461487

Following gene: 77461485

Centisome position: 92.03

GC content: 63.32

Gene sequence:

>1164_bases
ATGACCGTGTTGAAGATGTCCGACCTCGATCTGCAAGGTAAGCGCGTATTGATCCGCGAAGACCTCAACGTCCCAGTCAA
GGACGGTGTTGTCACCAGCGATGCGCGTATCCTGGCTTCGCTGCCGACCATCAAGCTGGCCCTGGAAAAAGGCGCGGCCG
TGATGGTCTGCTCGCACCTGGGTCGTCCGACCGAAGGCGAATTCTCTGCCGAGAACAGCCTCAAGCCTGTCGCCGACTAC
CTGAGCAAGGCCCTGGGCCGCGAAGTGCCGCTGGTGGCCGACTACCTGGGCGGCGTTGACGTCAAGGCCGGCGACATCGT
GCTGTTCGAAAACGTGCGCTTCAATAAGGGCGAGAAAAAGAACGCCGACGAATTGGCCCAGCAATATGCCGCCCTGTGCG
ACGTGTTCGTGATGGACGCTTTCGGCACCGCTCACCGTGCTGAAGGTTCGACCCACGGCGTCGCCAAGTTCGCCAAAGTC
GCCGCTGCCGGCCCGCTGCTGGCTGCTGAGCTCGACGCACTGGGCAAAGCCCTGGGCGCCCCGGCCAAGCCGATGGCGGC
CATCGTTGCCGGCTCCAAGGTCTCGACCAAGCTCGACGTACTGAACAGCCTGAGCCAGATCTGCGATCAACTGATCGTCG
GCGGCGGCATCGCCAACACCTTCCTCGCGGCGGCCGGTCACCCGGTCGGCAAGTCGCTGTACGAGCCGGACCTGCTGGAC
ACCGCGCGCGCCATCGCCGCCAAGGTCAGCGTGCCGCTGCCGGTCGACGTGGTGGTTGCCAAGGAATTCGCTGAAAGCGC
CGAAGCGACCGTGAAACTGATCGCTGACGTCGCTGCCGACGACATGATCCTCGACATCGGCCCGCAAACCGCGGCCAACT
TCGCCGAACTGCTGAAGTCGTCGAAAACCATCCTGTGGAACGGCCCGGTCGGCGTGTTCGAATTCGACCAGTTCGGCAAC
GGCACCAAAGTGCTGGCCGAAGCCATCGCAGAAAGCGCGGCGTTCTCGATTGCCGGCGGTGGCGACACCCTGGCGGCCAT
CGATAAATATGGCGTAGCGGAAAAGATCTCCTACATTTCCACCGGCGGCGGCGCGTTCCTCGAATTCGTCGAAGGCAAGG
TGCTGCCGGCCGTTGAAGTCCTGGAAAGCCGGGCCAAGGCCTGA

Upstream 100 bases:

>100_bases
CTGGTTCGACAACGAATGGGGTTTTGCCAACCGAATGCTGGATGTTGCAGAACACTATCTGCAAACAGCGACTTCAAAAA
AACCGTAGGAAGTGCGACCC

Downstream 100 bases:

>100_bases
GGCCGCCCGATTGGCCAGGCAAAGGAGTGTTCAGATGGTCAAGTCGTTAGCGCTGTTGCTGCTGACCGGTACGCTGGCGG
CCTGCGGGAGTAACCCGAAG

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MTVLKMSDLDLQGKRVLIREDLNVPVKDGVVTSDARILASLPTIKLALEKGAAVMVCSHLGRPTEGEFSAENSLKPVADY
LSKALGREVPLVADYLGGVDVKAGDIVLFENVRFNKGEKKNADELAQQYAALCDVFVMDAFGTAHRAEGSTHGVAKFAKV
AAAGPLLAAELDALGKALGAPAKPMAAIVAGSKVSTKLDVLNSLSQICDQLIVGGGIANTFLAAAGHPVGKSLYEPDLLD
TARAIAAKVSVPLPVDVVVAKEFAESAEATVKLIADVAADDMILDIGPQTAANFAELLKSSKTILWNGPVGVFEFDQFGN
GTKVLAEAIAESAAFSIAGGGDTLAAIDKYGVAEKISYISTGGGAFLEFVEGKVLPAVEVLESRAKA

Sequences:

>Translated_387_residues
MTVLKMSDLDLQGKRVLIREDLNVPVKDGVVTSDARILASLPTIKLALEKGAAVMVCSHLGRPTEGEFSAENSLKPVADY
LSKALGREVPLVADYLGGVDVKAGDIVLFENVRFNKGEKKNADELAQQYAALCDVFVMDAFGTAHRAEGSTHGVAKFAKV
AAAGPLLAAELDALGKALGAPAKPMAAIVAGSKVSTKLDVLNSLSQICDQLIVGGGIANTFLAAAGHPVGKSLYEPDLLD
TARAIAAKVSVPLPVDVVVAKEFAESAEATVKLIADVAADDMILDIGPQTAANFAELLKSSKTILWNGPVGVFEFDQFGN
GTKVLAEAIAESAAFSIAGGGDTLAAIDKYGVAEKISYISTGGGAFLEFVEGKVLPAVEVLESRAKA
>Mature_386_residues
TVLKMSDLDLQGKRVLIREDLNVPVKDGVVTSDARILASLPTIKLALEKGAAVMVCSHLGRPTEGEFSAENSLKPVADYL
SKALGREVPLVADYLGGVDVKAGDIVLFENVRFNKGEKKNADELAQQYAALCDVFVMDAFGTAHRAEGSTHGVAKFAKVA
AAGPLLAAELDALGKALGAPAKPMAAIVAGSKVSTKLDVLNSLSQICDQLIVGGGIANTFLAAAGHPVGKSLYEPDLLDT
ARAIAAKVSVPLPVDVVVAKEFAESAEATVKLIADVAADDMILDIGPQTAANFAELLKSSKTILWNGPVGVFEFDQFGNG
TKVLAEAIAESAAFSIAGGGDTLAAIDKYGVAEKISYISTGGGAFLEFVEGKVLPAVEVLESRAKA

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505763, Length=412, Percent_Identity=37.8640776699029, Blast_Score=261, Evalue=6e-70,
Organism=Homo sapiens, GI31543397, Length=412, Percent_Identity=38.1067961165049, Blast_Score=260, Evalue=2e-69,
Organism=Escherichia coli, GI1789294, Length=386, Percent_Identity=70.9844559585492, Blast_Score=548, Evalue=1e-157,
Organism=Caenorhabditis elegans, GI17508823, Length=415, Percent_Identity=42.4096385542169, Blast_Score=283, Evalue=1e-76,
Organism=Saccharomyces cerevisiae, GI6319857, Length=416, Percent_Identity=40.8653846153846, Blast_Score=261, Evalue=1e-70,
Organism=Drosophila melanogaster, GI17136394, Length=414, Percent_Identity=41.304347826087, Blast_Score=256, Evalue=2e-68,
Organism=Drosophila melanogaster, GI24581203, Length=411, Percent_Identity=38.9294403892944, Blast_Score=246, Evalue=2e-65,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824 [H]

Pfam domain/function: PF00162 PGK [H]

EC number: =2.7.2.3 [H]

Molecular weight: Translated: 40092; Mature: 39961

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00111 PGLYCERATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLKMSDLDLQGKRVLIREDLNVPVKDGVVTSDARILASLPTIKLALEKGAAVMVCSHL
CCEEEECCCCCCCCEEEEECCCCCCCCCCEEECCCHHHHHCCHHEEEHHCCCEEEEHHHC
GRPTEGEFSAENSLKPVADYLSKALGREVPLVADYLGGVDVKAGDIVLFENVRFNKGEKK
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCEEEEECCCCCCCCCC
NADELAQQYAALCDVFVMDAFGTAHRAEGSTHGVAKFAKVAAAGPLLAAELDALGKALGA
CHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
PAKPMAAIVAGSKVSTKLDVLNSLSQICDQLIVGGGIANTFLAAAGHPVGKSLYEPDLLD
CCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHH
TARAIAAKVSVPLPVDVVVAKEFAESAEATVKLIADVAADDMILDIGPQTAANFAELLKS
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHC
SKTILWNGPVGVFEFDQFGNGTKVLAEAIAESAAFSIAGGGDTLAAIDKYGVAEKISYIS
CCEEEECCCCCEEEHHCCCCHHHHHHHHHHHHHCEEEECCCCHHHHHHHCCHHHHHHHHC
TGGGAFLEFVEGKVLPAVEVLESRAKA
CCCHHHHHHHCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
TVLKMSDLDLQGKRVLIREDLNVPVKDGVVTSDARILASLPTIKLALEKGAAVMVCSHL
CEEEECCCCCCCCEEEEECCCCCCCCCCEEECCCHHHHHCCHHEEEHHCCCEEEEHHHC
GRPTEGEFSAENSLKPVADYLSKALGREVPLVADYLGGVDVKAGDIVLFENVRFNKGEKK
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCEEEEECCCCCCCCCC
NADELAQQYAALCDVFVMDAFGTAHRAEGSTHGVAKFAKVAAAGPLLAAELDALGKALGA
CHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
PAKPMAAIVAGSKVSTKLDVLNSLSQICDQLIVGGGIANTFLAAAGHPVGKSLYEPDLLD
CCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHH
TARAIAAKVSVPLPVDVVVAKEFAESAEATVKLIADVAADDMILDIGPQTAANFAELLKS
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHC
SKTILWNGPVGVFEFDQFGNGTKVLAEAIAESAAFSIAGGGDTLAAIDKYGVAEKISYIS
CCEEEECCCCCEEEHHCCCCHHHHHHHHHHHHHCEEEECCCCHHHHHHHCCHHHHHHHHC
TGGGAFLEFVEGKVLPAVEVLESRAKA
CCCHHHHHHHCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA