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The map label for this gene is epd [H]

Identifier: 77461487

GI number: 77461487

Start: 5925247

End: 5926299

Strand: Reverse

Name: epd [H]

Synonym: Pfl01_5266

Alternate gene names: 77461487

Gene position: 5926299-5925247 (Counterclockwise)

Preceding gene: 77461488

Following gene: 77461486

Centisome position: 92.05

GC content: 62.3

Gene sequence:

>1053_bases
ATGCCTCAACCGCGTCCCTACAAAGTTGCACTCAACGGCTACGGCCGGATCGGTCGTTGCGTCTTGCGTGCGTTGTTCGA
GCGAGGCTCGGCGGCAGGGTTTGAAATTGTCGCGATCAACGATCTGGCCGACATGGCCAGCATCGAATACCTGACACGCT
TCGACTCCACTCACGGCCGGTTCCCGGGCGAGGTGAAGGTCGAGGGCGATTGTCTGCATATTAATGGCCACTGCGTGAAG
GTCCTGCGCAGTGCCACCCCCGAAGGCATCGATTGGGCGTCGCTGGGTGTCGATCTGGTGCTCGAATGCTCCGGCGCCTG
GCACACCCGCGCAGACGGCCAGCGTTTTCTCGACGCCGGCGCGCCGCGTGTGCTGTTTTCGCAGCCGATGGCCAGCGAGG
CGGATGTCGATGCCACCATCGTCTACGGCGTCAATCAGGATTGCCTGACCGGCGACGAACTGCTGGTGTCCAACGCCTCC
TGCACCACCAACTGCGGCGTGCCGCTGTTGCGTCTGCTGGATCAGGCGGTCGGACTGGATTACGTGTCGATCACTACGAT
TCACTCGGCGATGAACGATCAGCCGGTGATCGACGCCTATCACCACGAAGACCTGCGCCGCACCCGCTCGGCGTTCCAGT
CGGTGATCCCGGTGTCCACCGGTCTGGCGCGTGGTATCGAGCGCCTGCTGCCGGAACTTGCCGGGCGAATTCAGGCCAAA
GCCGTACGCGTGCCGACGGTCAACGTGTCCTGCCTCGACATCACGATGCAGACCGCGAGCGACACCGACGCCGGCGAGGT
CAACCGGATCCTGCGCGACGCTGCCACCAGCGGCCCGCTCAAAGGCCTGTTGGCCTACACCGAGCTGCCCCACGCCAGTT
GTGATTTCAACCATGACCCACATTCGGCCATCGTCGATGCCAGTCAGACCCGCGTTTCCGGCCCACGGCTGGTGAACATC
CTGGCCTGGTTCGACAACGAATGGGGTTTTGCCAACCGAATGCTGGATGTTGCAGAACACTATCTGCAAACAGCGACTTC
AAAAAAACCGTAG

Upstream 100 bases:

>100_bases
ACAGGGTTATGTATGACTCATGTGGGAGCGAGCTTGCTCGCGATAGCGATGGTTCAGGCGCCATCGCATCAACGGATACA
CCACGGTAATCGAGAACCCC

Downstream 100 bases:

>100_bases
GAAGTGCGACCCATGACCGTGTTGAAGATGTCCGACCTCGATCTGCAAGGTAAGCGCGTATTGATCCGCGAAGACCTCAA
CGTCCCAGTCAAGGACGGTG

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: E4PDH [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MPQPRPYKVALNGYGRIGRCVLRALFERGSAAGFEIVAINDLADMASIEYLTRFDSTHGRFPGEVKVEGDCLHINGHCVK
VLRSATPEGIDWASLGVDLVLECSGAWHTRADGQRFLDAGAPRVLFSQPMASEADVDATIVYGVNQDCLTGDELLVSNAS
CTTNCGVPLLRLLDQAVGLDYVSITTIHSAMNDQPVIDAYHHEDLRRTRSAFQSVIPVSTGLARGIERLLPELAGRIQAK
AVRVPTVNVSCLDITMQTASDTDAGEVNRILRDAATSGPLKGLLAYTELPHASCDFNHDPHSAIVDASQTRVSGPRLVNI
LAWFDNEWGFANRMLDVAEHYLQTATSKKP

Sequences:

>Translated_350_residues
MPQPRPYKVALNGYGRIGRCVLRALFERGSAAGFEIVAINDLADMASIEYLTRFDSTHGRFPGEVKVEGDCLHINGHCVK
VLRSATPEGIDWASLGVDLVLECSGAWHTRADGQRFLDAGAPRVLFSQPMASEADVDATIVYGVNQDCLTGDELLVSNAS
CTTNCGVPLLRLLDQAVGLDYVSITTIHSAMNDQPVIDAYHHEDLRRTRSAFQSVIPVSTGLARGIERLLPELAGRIQAK
AVRVPTVNVSCLDITMQTASDTDAGEVNRILRDAATSGPLKGLLAYTELPHASCDFNHDPHSAIVDASQTRVSGPRLVNI
LAWFDNEWGFANRMLDVAEHYLQTATSKKP
>Mature_349_residues
PQPRPYKVALNGYGRIGRCVLRALFERGSAAGFEIVAINDLADMASIEYLTRFDSTHGRFPGEVKVEGDCLHINGHCVKV
LRSATPEGIDWASLGVDLVLECSGAWHTRADGQRFLDAGAPRVLFSQPMASEADVDATIVYGVNQDCLTGDELLVSNASC
TTNCGVPLLRLLDQAVGLDYVSITTIHSAMNDQPVIDAYHHEDLRRTRSAFQSVIPVSTGLARGIERLLPELAGRIQAKA
VRVPTVNVSCLDITMQTASDTDAGEVNRILRDAATSGPLKGLLAYTELPHASCDFNHDPHSAIVDASQTRVSGPRLVNIL
AWFDNEWGFANRMLDVAEHYLQTATSKKP

Specific function: Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate [H]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=334, Percent_Identity=37.7245508982036, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI7657116, Length=341, Percent_Identity=36.3636363636364, Blast_Score=220, Evalue=1e-57,
Organism=Escherichia coli, GI1789295, Length=329, Percent_Identity=53.7993920972644, Blast_Score=360, Evalue=1e-101,
Organism=Escherichia coli, GI1788079, Length=333, Percent_Identity=38.1381381381381, Blast_Score=237, Evalue=9e-64,
Organism=Caenorhabditis elegans, GI17534677, Length=337, Percent_Identity=37.9821958456973, Blast_Score=238, Evalue=5e-63,
Organism=Caenorhabditis elegans, GI17534679, Length=337, Percent_Identity=37.3887240356083, Blast_Score=235, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI17568413, Length=347, Percent_Identity=37.1757925072046, Blast_Score=232, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI32566163, Length=347, Percent_Identity=36.8876080691643, Blast_Score=229, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6322468, Length=334, Percent_Identity=37.7245508982036, Blast_Score=255, Evalue=8e-69,
Organism=Saccharomyces cerevisiae, GI6321631, Length=336, Percent_Identity=38.0952380952381, Blast_Score=251, Evalue=2e-67,
Organism=Saccharomyces cerevisiae, GI6322409, Length=336, Percent_Identity=37.202380952381, Blast_Score=244, Evalue=1e-65,
Organism=Drosophila melanogaster, GI17933600, Length=338, Percent_Identity=37.8698224852071, Blast_Score=241, Evalue=4e-64,
Organism=Drosophila melanogaster, GI18110149, Length=338, Percent_Identity=37.8698224852071, Blast_Score=241, Evalue=4e-64,
Organism=Drosophila melanogaster, GI85725000, Length=338, Percent_Identity=37.5739644970414, Blast_Score=240, Evalue=1e-63,
Organism=Drosophila melanogaster, GI22023983, Length=338, Percent_Identity=37.5739644970414, Blast_Score=240, Evalue=1e-63,
Organism=Drosophila melanogaster, GI19922412, Length=330, Percent_Identity=34.8484848484849, Blast_Score=209, Evalue=2e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006422
- InterPro:   IPR020831
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.72 [H]

Molecular weight: Translated: 38010; Mature: 37879

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQPRPYKVALNGYGRIGRCVLRALFERGSAAGFEIVAINDLADMASIEYLTRFDSTHGR
CCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCC
FPGEVKVEGDCLHINGHCVKVLRSATPEGIDWASLGVDLVLECSGAWHTRADGQRFLDAG
CCCEEEEECCEEEECHHHHHHHHHCCCCCCCHHHCCEEEEEECCCCCCCCCCCHHHHHCC
APRVLFSQPMASEADVDATIVYGVNQDCLTGDELLVSNASCTTNCGVPLLRLLDQAVGLD
CCEEEECCCCCCCCCCCEEEEEECCCCCCCCCHHEEECCCCCCCCCHHHHHHHHHHHCCC
YVSITTIHSAMNDQPVIDAYHHEDLRRTRSAFQSVIPVSTGLARGIERLLPELAGRIQAK
HHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHE
AVRVPTVNVSCLDITMQTASDTDAGEVNRILRDAATSGPLKGLLAYTELPHASCDFNHDP
EEECCEEEEEEEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCC
HSAIVDASQTRVSGPRLVNILAWFDNEWGFANRMLDVAEHYLQTATSKKP
CHHHCCCCHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PQPRPYKVALNGYGRIGRCVLRALFERGSAAGFEIVAINDLADMASIEYLTRFDSTHGR
CCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCC
FPGEVKVEGDCLHINGHCVKVLRSATPEGIDWASLGVDLVLECSGAWHTRADGQRFLDAG
CCCEEEEECCEEEECHHHHHHHHHCCCCCCCHHHCCEEEEEECCCCCCCCCCCHHHHHCC
APRVLFSQPMASEADVDATIVYGVNQDCLTGDELLVSNASCTTNCGVPLLRLLDQAVGLD
CCEEEECCCCCCCCCCCEEEEEECCCCCCCCCHHEEECCCCCCCCCHHHHHHHHHHHCCC
YVSITTIHSAMNDQPVIDAYHHEDLRRTRSAFQSVIPVSTGLARGIERLLPELAGRIQAK
HHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHE
AVRVPTVNVSCLDITMQTASDTDAGEVNRILRDAATSGPLKGLLAYTELPHASCDFNHDP
EEECCEEEEEEEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCC
HSAIVDASQTRVSGPRLVNILAWFDNEWGFANRMLDVAEHYLQTATSKKP
CHHHCCCCHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA