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The map label for this gene is atoC [H]

Identifier: 77461405

GI number: 77461405

Start: 5831442

End: 5831888

Strand: Reverse

Name: atoC [H]

Synonym: Pfl01_5184

Alternate gene names: 77461405

Gene position: 5831888-5831442 (Counterclockwise)

Preceding gene: 77461414

Following gene: 77461403

Centisome position: 90.58

GC content: 60.4

Gene sequence:

>447_bases
ATGTCCGACCACGATATTTTGAGCGACGCCGAGCGGGAAGCGCTCAGCGCCGTCATGCTGGAACCCGACCTGCCGCCGCA
GCGGGTACTGATTGTCGACGACGACAAGGATGCCCGCGAGTTGTTGTCGGAGATCCTGGCACTGGATGGCATTCGCTGCC
TGACCGCGGCCAGCGGCGAAACCGCGCTGAAAATGCTCGCGGAAAAACCTTCGATCGGGTTGGTGATCACCGACCTGCGC
ATGGGCAACGTCGATGGCCTGGAGCTGATCCGCCAGGTGCGCGAATCCGTCAGGGCGGCGCTGCCGATCATCATTGTGTC
CGGTGATGCCGACGTGAAGGATGCGATTGCGGCGATGCATTTGAGCGTAGTGGATTTCCTGCTCAAACCTATCGATACCG
CCAAATTGCTTGGACTGGTCAGGCATGAGTTGGGGATCGAGCCCTAG

Upstream 100 bases:

>100_bases
CGCCCCTTGGAAAAAAATCCGACGAAGTGCACATTGAAGCTCTGCCCAGCGATGTCTGACCACTGTGCCAGGGGATCGAA
TTGAAAACGTAGAGAACGCC

Downstream 100 bases:

>100_bases
CCAATCCGGCGCAAACAAAAAAAGCCCTGATCGAAAGATCAGGGCTTTTTCGTGTCCGGCATCCGCGCAGGTTAAAGGCC
GTTGGCAGCCTTGAACTCGC

Product: response regulator receiver domain-containing protein

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 148; Mature: 147

Protein sequence:

>148_residues
MSDHDILSDAEREALSAVMLEPDLPPQRVLIVDDDKDARELLSEILALDGIRCLTAASGETALKMLAEKPSIGLVITDLR
MGNVDGLELIRQVRESVRAALPIIIVSGDADVKDAIAAMHLSVVDFLLKPIDTAKLLGLVRHELGIEP

Sequences:

>Translated_148_residues
MSDHDILSDAEREALSAVMLEPDLPPQRVLIVDDDKDARELLSEILALDGIRCLTAASGETALKMLAEKPSIGLVITDLR
MGNVDGLELIRQVRESVRAALPIIIVSGDADVKDAIAAMHLSVVDFLLKPIDTAKLLGLVRHELGIEP
>Mature_147_residues
SDHDILSDAEREALSAVMLEPDLPPQRVLIVDDDKDARELLSEILALDGIRCLTAASGETALKMLAEKPSIGLVITDLRM
GNVDGLELIRQVRESVRAALPIIIVSGDADVKDAIAAMHLSVVDFLLKPIDTAKLLGLVRHELGIEP

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=122, Percent_Identity=32.7868852459016, Blast_Score=71, Evalue=2e-14,
Organism=Escherichia coli, GI1790299, Length=112, Percent_Identity=34.8214285714286, Blast_Score=69, Evalue=9e-14,
Organism=Escherichia coli, GI1788905, Length=107, Percent_Identity=37.3831775700935, Blast_Score=69, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 15981; Mature: 15850

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDHDILSDAEREALSAVMLEPDLPPQRVLIVDDDKDARELLSEILALDGIRCLTAASGE
CCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCHHEECCCCH
TALKMLAEKPSIGLVITDLRMGNVDGLELIRQVRESVRAALPIIIVSGDADVKDAIAAMH
HHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHH
LSVVDFLLKPIDTAKLLGLVRHELGIEP
HHHHHHHHCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SDHDILSDAEREALSAVMLEPDLPPQRVLIVDDDKDARELLSEILALDGIRCLTAASGE
CCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCHHEECCCCH
TALKMLAEKPSIGLVITDLRMGNVDGLELIRQVRESVRAALPIIIVSGDADVKDAIAAMH
HHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHH
LSVVDFLLKPIDTAKLLGLVRHELGIEP
HHHHHHHHCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]