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The map label for this gene is estA [H]

Identifier: 77461338

GI number: 77461338

Start: 5748373

End: 5750283

Strand: Direct

Name: estA [H]

Synonym: Pfl01_5117

Alternate gene names: 77461338

Gene position: 5748373-5750283 (Clockwise)

Preceding gene: 77461332

Following gene: 77461349

Centisome position: 89.28

GC content: 62.95

Gene sequence:

>1911_bases
ATGATCAAACAGACGTTGTTTGTACCGCTCGCCGGATGCCTGCTCGCGATGGCCTGCGCCCAGGCGAACGCCGCACCCAA
TCCTTATTCGAATTTCGTGGTCTTCGGCGACAGCCTGAGCGATGCGGGGACTTTCACCGACAGCGGCGGCCCGGCCGGCG
CCACACAGCGCTACACCAACCGCACCGGTCCGGTGTATTTGGACGGCAGCGGTGAACTCCGCTCGCTGAACTCGACGCAA
CTGCTCGGTGGCCGACTCGGCTTCACACCGGATCAAACCGCCTCCTCGTCCTCAGCAGTACGTGCCGGCCAAGGCCAGCC
GGATGGTAACAACTGGGCTGTCGGCGGCTACCGCACCGACCAGATTCTCGACTCGATCACCAGCCAGTCCGCCACCGGCG
AACGCACCCGCGCCGGTTATCTGCCGTCGAACGGTTTCCGTGCTGACCCGAATGCCTTGTATTACCTGACCGGGGGCGGC
AACGACTTCCTTCAGGGCCGCGTCACCAGCCTGCCTCAGGCGAATGCCGCCGCCGATCGACTGGTCGACAGCGTACGCAC
ACTGCAAGGTGCCGGCGCCCGCTACATCATGGTCTGGCTGTTGCCGGACATCGGCCTGACCCCGGCCATCAACGGCTCGC
CGCTGCAGGCCTTCACCTCGCAACTCAGCACCCAGTTCAACACCGAACTGGTCAGCCAGTTGCAGAGCGTCAACGCCAAC
GTGATTCCGCTGAACGTCCCGGTTCTGCTCAAAGAGGCGTTCGCCAATCCGGCGCAATTCGGTCTGGCGACCGACCAGAA
TCTGGTCGGCACCTGCTTCAGCGGCAGCGGCTGCACCGAGAACGCCCGGTATGGCATCAACAGCGCCACCCCGGATCCGA
CCAAGCTGATCTACAACGACGCCGTCCACCCGACCGAAGCCGGGCAGCGCCTGATTGCCGATTACGCTTACTCGCTGCTG
GCCGCGCCATGGGAAGCGACTCTGCTTCCGCAAATGGCCCAGGGCACCTTGCGCTCGCATCAGGATGAACTGCGCAACCA
GTGGCTGGCGGATTGGGAAAACTGGCAGGCCGTTGGCCAATGGCGGGCGATTGTTGCCGGTGGTGGCCAGCATCAGGACT
TCGACAGCCAGCGCAGCGGCGCCAGCGCCGACGGTAACGGTTACAACCTGAACATCGGCGGCAGCTACCGTCTCAACGAC
GCCTGGCGCGTGGGCGTGGCGGCCGGTTTCTACAATCAGAAGCTCGAGGCCGGCGACAACGACTCGGACTACAAACTGAA
CACTTATCTGGGCACCGCGTTCGCCCAGTACCAGCAGAACCGCTGGTGGGGTGACGCCGCCGTGACCGCCGGACATCTGG
ATTACGACAGCCTCAAACGCAAATTCCAGCTGGGGGTAAACGAACGCGGCGAGAAAGGCGATACCGACGGCTATGTTCTG
GCCTTCAGTGGACGCGTGGGTTACGACATTGCGCCAGAGGCAAGCAGCCCATGGCACCTGTCGCCGTTCGTCAGCGCCGA
TTTCGCCAAGGTTGAAGTCGATGGTTACTCGGAAAACGGCGCCGACTCCACCGCGCTGACGTTCGATGACCAGTCGCGCA
TCTCCCGGCGCCTGGGCCTCGGGATCCAGGGCAAGTACCAGATCACCTCGCAGACCCAGGTGTTCGGCGAACTGGCCCAC
GAACGTGAGTACAACGACGACACCCAGAATGTGACGATGAACCTCAACAGCCTGCCGAACAACCGCTACACCCTGGCCGG
CTATACCCCTCAGACCAACCTGAACCGCCTGAACCTGGGCGTGAGCCACAACCTCACCAAGGATCTGGCATTACGTGCCA
GCTACGACATCCGCAAGGATGACGACTTCACCCAGCAAGGGATCAACGTCGGCGTAGCGCTCGACTTCTGA

Upstream 100 bases:

>100_bases
GGGATAAAACAATGGGAGGCTTGACGACCGATGGCAAAACGCCGGAAGTTTTTGGTACTGTCGTTTCGTTCACTACAACA
ATAAATAAACGGACTTGCTC

Downstream 100 bases:

>100_bases
TTCGCAGGCAAAAAAAATGCGGCGCCTTCACAGGCGCCGCATTTTTTTAGGCTGAATCATCAATGACTCAGTCCGGGGTT
TGCTCGGCCAGCGCAACAGC

Product: outer membrane autotransporter barrel protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 636; Mature: 636

Protein sequence:

>636_residues
MIKQTLFVPLAGCLLAMACAQANAAPNPYSNFVVFGDSLSDAGTFTDSGGPAGATQRYTNRTGPVYLDGSGELRSLNSTQ
LLGGRLGFTPDQTASSSSAVRAGQGQPDGNNWAVGGYRTDQILDSITSQSATGERTRAGYLPSNGFRADPNALYYLTGGG
NDFLQGRVTSLPQANAAADRLVDSVRTLQGAGARYIMVWLLPDIGLTPAINGSPLQAFTSQLSTQFNTELVSQLQSVNAN
VIPLNVPVLLKEAFANPAQFGLATDQNLVGTCFSGSGCTENARYGINSATPDPTKLIYNDAVHPTEAGQRLIADYAYSLL
AAPWEATLLPQMAQGTLRSHQDELRNQWLADWENWQAVGQWRAIVAGGGQHQDFDSQRSGASADGNGYNLNIGGSYRLND
AWRVGVAAGFYNQKLEAGDNDSDYKLNTYLGTAFAQYQQNRWWGDAAVTAGHLDYDSLKRKFQLGVNERGEKGDTDGYVL
AFSGRVGYDIAPEASSPWHLSPFVSADFAKVEVDGYSENGADSTALTFDDQSRISRRLGLGIQGKYQITSQTQVFGELAH
EREYNDDTQNVTMNLNSLPNNRYTLAGYTPQTNLNRLNLGVSHNLTKDLALRASYDIRKDDDFTQQGINVGVALDF

Sequences:

>Translated_636_residues
MIKQTLFVPLAGCLLAMACAQANAAPNPYSNFVVFGDSLSDAGTFTDSGGPAGATQRYTNRTGPVYLDGSGELRSLNSTQ
LLGGRLGFTPDQTASSSSAVRAGQGQPDGNNWAVGGYRTDQILDSITSQSATGERTRAGYLPSNGFRADPNALYYLTGGG
NDFLQGRVTSLPQANAAADRLVDSVRTLQGAGARYIMVWLLPDIGLTPAINGSPLQAFTSQLSTQFNTELVSQLQSVNAN
VIPLNVPVLLKEAFANPAQFGLATDQNLVGTCFSGSGCTENARYGINSATPDPTKLIYNDAVHPTEAGQRLIADYAYSLL
AAPWEATLLPQMAQGTLRSHQDELRNQWLADWENWQAVGQWRAIVAGGGQHQDFDSQRSGASADGNGYNLNIGGSYRLND
AWRVGVAAGFYNQKLEAGDNDSDYKLNTYLGTAFAQYQQNRWWGDAAVTAGHLDYDSLKRKFQLGVNERGEKGDTDGYVL
AFSGRVGYDIAPEASSPWHLSPFVSADFAKVEVDGYSENGADSTALTFDDQSRISRRLGLGIQGKYQITSQTQVFGELAH
EREYNDDTQNVTMNLNSLPNNRYTLAGYTPQTNLNRLNLGVSHNLTKDLALRASYDIRKDDDFTQQGINVGVALDF
>Mature_636_residues
MIKQTLFVPLAGCLLAMACAQANAAPNPYSNFVVFGDSLSDAGTFTDSGGPAGATQRYTNRTGPVYLDGSGELRSLNSTQ
LLGGRLGFTPDQTASSSSAVRAGQGQPDGNNWAVGGYRTDQILDSITSQSATGERTRAGYLPSNGFRADPNALYYLTGGG
NDFLQGRVTSLPQANAAADRLVDSVRTLQGAGARYIMVWLLPDIGLTPAINGSPLQAFTSQLSTQFNTELVSQLQSVNAN
VIPLNVPVLLKEAFANPAQFGLATDQNLVGTCFSGSGCTENARYGINSATPDPTKLIYNDAVHPTEAGQRLIADYAYSLL
AAPWEATLLPQMAQGTLRSHQDELRNQWLADWENWQAVGQWRAIVAGGGQHQDFDSQRSGASADGNGYNLNIGGSYRLND
AWRVGVAAGFYNQKLEAGDNDSDYKLNTYLGTAFAQYQQNRWWGDAAVTAGHLDYDSLKRKFQLGVNERGEKGDTDGYVL
AFSGRVGYDIAPEASSPWHLSPFVSADFAKVEVDGYSENGADSTALTFDDQSRISRRLGLGIQGKYQITSQTQVFGELAH
EREYNDDTQNVTMNLNSLPNNRYTLAGYTPQTNLNRLNLGVSHNLTKDLALRASYDIRKDDDFTQQGINVGVALDF

Specific function: Unknown

COG id: COG3240

COG function: function code IR; Phospholipase/lecithinase/hemolysin

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 autotransporter (TC 1.B.12) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005546
- InterPro:   IPR013830
- InterPro:   IPR013831
- InterPro:   IPR017186
- InterPro:   IPR001087
- InterPro:   IPR008265
- InterPro:   IPR006315 [H]

Pfam domain/function: PF03797 Autotransporter; PF00657 Lipase_GDSL [H]

EC number: =3.1.1.1 [H]

Molecular weight: Translated: 68639; Mature: 68639

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01098 LIPASE_GDSL_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKQTLFVPLAGCLLAMACAQANAAPNPYSNFVVFGDSLSDAGTFTDSGGPAGATQRYTN
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHCC
RTGPVYLDGSGELRSLNSTQLLGGRLGFTPDQTASSSSAVRAGQGQPDGNNWAVGGYRTD
CCCCEEECCCCCEECCCCCCEECCCCCCCCCCCCCCCCCEECCCCCCCCCCEEECCEEHH
QILDSITSQSATGERTRAGYLPSNGFRADPNALYYLTGGGNDFLQGRVTSLPQANAAADR
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHCCHHHCCCCCHHHHHH
LVDSVRTLQGAGARYIMVWLLPDIGLTPAINGSPLQAFTSQLSTQFNTELVSQLQSVNAN
HHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
VIPLNVPVLLKEAFANPAQFGLATDQNLVGTCFSGSGCTENARYGINSATPDPTKLIYND
EEEECCHHHHHHHHCCCHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEEECC
AVHPTEAGQRLIADYAYSLLAAPWEATLLPQMAQGTLRSHQDELRNQWLADWENWQAVGQ
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCC
WRAIVAGGGQHQDFDSQRSGASADGNGYNLNIGGSYRLNDAWRVGVAAGFYNQKLEAGDN
EEEEEECCCCCCCCCHHCCCCCCCCCCEEEECCCCEEECCCEEEEEEECCCCCCCCCCCC
DSDYKLNTYLGTAFAQYQQNRWWGDAAVTAGHLDYDSLKRKFQLGVNERGEKGDTDGYVL
CCCEEEEHHHHHHHHHHHHCCEECCHHEEECCCCHHHHHHHHHCCCCCCCCCCCCCCEEE
AFSGRVGYDIAPEASSPWHLSPFVSADFAKVEVDGYSENGADSTALTFDDQSRISRRLGL
EECCCCCCEECCCCCCCEECCCCCCCCEEEEEECCCCCCCCCCEEEEECCHHHHHHHHCC
GIQGKYQITSQTQVFGELAHEREYNDDTQNVTMNLNSLPNNRYTLAGYTPQTNLNRLNLG
CCCCEEEECHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEECCCCCCCCEEEEC
VSHNLTKDLALRASYDIRKDDDFTQQGINVGVALDF
CCCCCCHHHEEEECCCCCCCCCHHHCCCEEEEEECC
>Mature Secondary Structure
MIKQTLFVPLAGCLLAMACAQANAAPNPYSNFVVFGDSLSDAGTFTDSGGPAGATQRYTN
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHCC
RTGPVYLDGSGELRSLNSTQLLGGRLGFTPDQTASSSSAVRAGQGQPDGNNWAVGGYRTD
CCCCEEECCCCCEECCCCCCEECCCCCCCCCCCCCCCCCEECCCCCCCCCCEEECCEEHH
QILDSITSQSATGERTRAGYLPSNGFRADPNALYYLTGGGNDFLQGRVTSLPQANAAADR
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHCCHHHCCCCCHHHHHH
LVDSVRTLQGAGARYIMVWLLPDIGLTPAINGSPLQAFTSQLSTQFNTELVSQLQSVNAN
HHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
VIPLNVPVLLKEAFANPAQFGLATDQNLVGTCFSGSGCTENARYGINSATPDPTKLIYND
EEEECCHHHHHHHHCCCHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEEECC
AVHPTEAGQRLIADYAYSLLAAPWEATLLPQMAQGTLRSHQDELRNQWLADWENWQAVGQ
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCC
WRAIVAGGGQHQDFDSQRSGASADGNGYNLNIGGSYRLNDAWRVGVAAGFYNQKLEAGDN
EEEEEECCCCCCCCCHHCCCCCCCCCCEEEECCCCEEECCCEEEEEEECCCCCCCCCCCC
DSDYKLNTYLGTAFAQYQQNRWWGDAAVTAGHLDYDSLKRKFQLGVNERGEKGDTDGYVL
CCCEEEEHHHHHHHHHHHHCCEECCHHEEECCCCHHHHHHHHHCCCCCCCCCCCCCCEEE
AFSGRVGYDIAPEASSPWHLSPFVSADFAKVEVDGYSENGADSTALTFDDQSRISRRLGL
EECCCCCCEECCCCCCCEECCCCCCCCEEEEEECCCCCCCCCCEEEEECCHHHHHHHHCC
GIQGKYQITSQTQVFGELAHEREYNDDTQNVTMNLNSLPNNRYTLAGYTPQTNLNRLNLG
CCCCEEEECHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEECCCCCCCCEEEEC
VSHNLTKDLALRASYDIRKDDDFTQQGINVGVALDF
CCCCCCHHHEEEECCCCCCCCCHHHCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10559163; 10984043 [H]