Click here to switch to the map view.

The map label for this gene is trpD [H]

Identifier: 77461335

GI number: 77461335

Start: 5746317

End: 5747366

Strand: Reverse

Name: trpD [H]

Synonym: Pfl01_5114

Alternate gene names: 77461335

Gene position: 5747366-5746317 (Counterclockwise)

Preceding gene: 77461336

Following gene: 77461334

Centisome position: 89.27

GC content: 61.81

Gene sequence:

>1050_bases
ATGAATATCAAGACAGCCCTGAGCCGTATCGTCGATCACCTCGACCTCAGCACCGATGAAATGCGCGACGTGATGCGCGA
AATCATGACCGGCCAATGCACTGACGCGCAGATCGGCGCGTTCATGATGGCCATGCGCATGAAGAGCGAGAGCATCGACG
AGATCGTCGGCGCCGTGTCGGTGATGCGCGAACTGGCGGACAAGGTGGAACTCAAGACCCTCGACCGCGTGGTCGATGTG
GTCGGCACCGGCGGTGACGGGGCGAACATTTTCAACGTGTCGACCGCGTCTTCCTTCGTGGTCGCCGCGGCTGGCTGCAC
CGTGGCCAAACACGGTAACCGTGCAGTGTCGGGCAAGAGCGGCAGTGCCGACTTGCTGGAAGCCGCCGGCATCTACCTCA
ACCTGACCCCGGTTCAGGTGGCGCGCTGCATCGACAACGTCGGCATCGGCTTCATGTTTGCCCAGACTCACCACAAAGCC
ATGAAGTACGCCGCCGGCCCGCGTCGCGATCTCGGCCTGCGCACGCTGTTCAACATGCTCGGCCCGCTTACGAATCCGGC
CGGTGTGAAACATCAGGTGGTGGGCGTGTTCACCCCGGCGCTGTGCCGGCCGTTGGCTGAAGTCTTGCAGCGTCTGGGCA
GCAAGCATGTGCTGGTGGTGCATTCGAAGGACGGTCTGGACGAATTCAGTCTGGCGGCGCCGACTTTTGTCGCCGAGCTG
AAGGACGATCAGATCACCGAATATTGGGTCGAGCCGGAGGATCTGGGCATGAAGAGCCAGAGCCTGCACGGTCTGTCGGT
CGAAGGCCCGGAAGCCTCGCTGGCGCTGATCCGCGATGCACTCGGCAAGCGCAAGACCGAGAACGGTCAGAAGGCTGCCG
AAATGATCGTGCTCAATGCCGGTGCGGCGCTGTACGCAGCCGACCTGGCGACAAGTCTGAAAGAGGGCGTGGCACTGGCC
CACGACGCTCTGCACACCGGTCTTGCTCGGGAAAAACTCGAGGAGTTGGGTGCCTTTACCGCGGTATTCAAAGTGGAGAA
TGAGGGATGA

Upstream 100 bases:

>100_bases
GGGCGTACAGTTCCACCCGGAATCGATCCTCACCGAACAGGGCCATGAACTGTTCGCCAACTTCCTCAAACAAACCGGCG
GCACGCGCTAAGGACTTTCC

Downstream 100 bases:

>100_bases
GTGTACCGACGGTTCTGGAAAACATTCTGGCCCGCAAGTTTCAGGAAGTCGCCGAGCGTAGCGCCCGTGTGAGCCTGAGC
GAGCTGGAAAGTCTGGCCAA

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MNIKTALSRIVDHLDLSTDEMRDVMREIMTGQCTDAQIGAFMMAMRMKSESIDEIVGAVSVMRELADKVELKTLDRVVDV
VGTGGDGANIFNVSTASSFVVAAAGCTVAKHGNRAVSGKSGSADLLEAAGIYLNLTPVQVARCIDNVGIGFMFAQTHHKA
MKYAAGPRRDLGLRTLFNMLGPLTNPAGVKHQVVGVFTPALCRPLAEVLQRLGSKHVLVVHSKDGLDEFSLAAPTFVAEL
KDDQITEYWVEPEDLGMKSQSLHGLSVEGPEASLALIRDALGKRKTENGQKAAEMIVLNAGAALYAADLATSLKEGVALA
HDALHTGLAREKLEELGAFTAVFKVENEG

Sequences:

>Translated_349_residues
MNIKTALSRIVDHLDLSTDEMRDVMREIMTGQCTDAQIGAFMMAMRMKSESIDEIVGAVSVMRELADKVELKTLDRVVDV
VGTGGDGANIFNVSTASSFVVAAAGCTVAKHGNRAVSGKSGSADLLEAAGIYLNLTPVQVARCIDNVGIGFMFAQTHHKA
MKYAAGPRRDLGLRTLFNMLGPLTNPAGVKHQVVGVFTPALCRPLAEVLQRLGSKHVLVVHSKDGLDEFSLAAPTFVAEL
KDDQITEYWVEPEDLGMKSQSLHGLSVEGPEASLALIRDALGKRKTENGQKAAEMIVLNAGAALYAADLATSLKEGVALA
HDALHTGLAREKLEELGAFTAVFKVENEG
>Mature_349_residues
MNIKTALSRIVDHLDLSTDEMRDVMREIMTGQCTDAQIGAFMMAMRMKSESIDEIVGAVSVMRELADKVELKTLDRVVDV
VGTGGDGANIFNVSTASSFVVAAAGCTVAKHGNRAVSGKSGSADLLEAAGIYLNLTPVQVARCIDNVGIGFMFAQTHHKA
MKYAAGPRRDLGLRTLFNMLGPLTNPAGVKHQVVGVFTPALCRPLAEVLQRLGSKHVLVVHSKDGLDEFSLAAPTFVAEL
KDDQITEYWVEPEDLGMKSQSLHGLSVEGPEASLALIRDALGKRKTENGQKAAEMIVLNAGAALYAADLATSLKEGVALA
HDALHTGLAREKLEELGAFTAVFKVENEG

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=282, Percent_Identity=40.0709219858156, Blast_Score=187, Evalue=9e-49,
Organism=Saccharomyces cerevisiae, GI6320561, Length=323, Percent_Identity=28.1733746130031, Blast_Score=116, Evalue=6e-27,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 37214; Mature: 37214

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIKTALSRIVDHLDLSTDEMRDVMREIMTGQCTDAQIGAFMMAMRMKSESIDEIVGAVS
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VMRELADKVELKTLDRVVDVVGTGGDGANIFNVSTASSFVVAAAGCTVAKHGNRAVSGKS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHCCCEEECCCCEEECCCC
GSADLLEAAGIYLNLTPVQVARCIDNVGIGFMFAQTHHKAMKYAAGPRRDLGLRTLFNML
CCHHHHHHCCCEEECHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCCCHHHHHHHHHH
GPLTNPAGVKHQVVGVFTPALCRPLAEVLQRLGSKHVLVVHSKDGLDEFSLAAPTFVAEL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHCHHHHHHC
KDDQITEYWVEPEDLGMKSQSLHGLSVEGPEASLALIRDALGKRKTENGQKAAEMIVLNA
CCCCHHHHCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHEEEEEC
GAALYAADLATSLKEGVALAHDALHTGLAREKLEELGAFTAVFKVENEG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCC
>Mature Secondary Structure
MNIKTALSRIVDHLDLSTDEMRDVMREIMTGQCTDAQIGAFMMAMRMKSESIDEIVGAVS
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VMRELADKVELKTLDRVVDVVGTGGDGANIFNVSTASSFVVAAAGCTVAKHGNRAVSGKS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHCCCEEECCCCEEECCCC
GSADLLEAAGIYLNLTPVQVARCIDNVGIGFMFAQTHHKAMKYAAGPRRDLGLRTLFNML
CCHHHHHHCCCEEECHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCCCHHHHHHHHHH
GPLTNPAGVKHQVVGVFTPALCRPLAEVLQRLGSKHVLVVHSKDGLDEFSLAAPTFVAEL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHCHHHHHHC
KDDQITEYWVEPEDLGMKSQSLHGLSVEGPEASLALIRDALGKRKTENGQKAAEMIVLNA
CCCCHHHHCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHEEEEEC
GAALYAADLATSLKEGVALAHDALHTGLAREKLEELGAFTAVFKVENEG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA