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The map label for this gene is thiL [H]

Identifier: 77461235

GI number: 77461235

Start: 5650084

End: 5651049

Strand: Reverse

Name: thiL [H]

Synonym: Pfl01_5014

Alternate gene names: 77461235

Gene position: 5651049-5650084 (Counterclockwise)

Preceding gene: 77461236

Following gene: 77461234

Centisome position: 87.77

GC content: 66.98

Gene sequence:

>966_bases
ATGGGCGAGTTTGAGCTGATCCGCAATTTCTTTGCCGCCGCGCCTTGTGCGCAGGGCGGCGAAGGCGTTGCACTGGGGAT
CGGCGATGACTGCGCCTTGCTGGCGGTTCCTTCCGGGGAACAGCTGGCGGTTTCCACCGATACGCTGGTGGCCGGCGTAC
ATTTCGCCGATCCCTGCGATCCGTTTCTGCTCGGTCAGCGCTCGCTGGCCGTGGCGGTCAGCGACCTCGCTGCCATGGGC
GCCACGCCCGTCGCCTTTACCCTTGCCCTGACTCTGCCGACGGTGACTGCCGATTGGCTGCAAGCCTATGCCCGCGGTTT
GAACCGCATGGCGCAGGGCTGCGGCGTGGCACTGGTCGGCGGCGACACGACGCGCGGGCCGTTGAGCCTGACCGTCACCG
TTTTCGGTCGCGTCCCGGCCGGCAAAGCGCTGACCCGCAGCGGCGCGCAGCCGGGCGATCTGCTGTGTGTCGGCGGCGAA
CTGGGCAATGCAGCCGGGGCCTTGCCGCTGGTGCTGGGTCAGCGTGACGCCGAACCACACATCGCTCAGCCGCTGCTCGA
TCATTACTGGTCGCCGCAACCGCAACTCGCCCTCGGTCAGGCCCTGCGTGGCAAGGCCACCTCGGCGTTGGACATCTCCG
ATGGGCTGCTCGCCGATTGCGGTCACATCGCACTGGCCTCGAAGGTCCGCCTCGAAGTCGAGCGCGAGCGCGTTCCGTTG
TCGGAGGCGCTGGTGGCGTTTCTCGGTCAGCGCGGCGCCGAACGTGCGGCGTTGAGCGGTGGCGATGATTACGTGCTGGC
CTTCACCTTGCCGTCCGTCGAGTTGCCGGCGTTGCTCGCCGATAGCTGGTCGATCCATGTGATCGGCCGCGTGACGCAAG
GGCAGGGCGTGGTGCTGCTGGATCGCGACGGGCACGACATCACCCCGCAAATCCGGGGTTATCAACATTTTCAGGAGTCA
CCGTGA

Upstream 100 bases:

>100_bases
GTTCGTCAACGGCGTGCTCGACAAGCTGGCTCCGCGCCTGCGTGAAGCTGAAGTGAAGGCGTTCAAGCGCTGATCGGCGC
TTGAATACTTTTTCTCGGCC

Downstream 100 bases:

>100_bases
CAGATCACCCGAAACAGGTTCCGGCCGAATTCGTTCCGCCGTCGGTCTGGCGCAATCCTTGGCATTTCCTCGCGTTCGGT
TTCGGCTCGGGCACCTTGCC

Product: thiamine monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MGEFELIRNFFAAAPCAQGGEGVALGIGDDCALLAVPSGEQLAVSTDTLVAGVHFADPCDPFLLGQRSLAVAVSDLAAMG
ATPVAFTLALTLPTVTADWLQAYARGLNRMAQGCGVALVGGDTTRGPLSLTVTVFGRVPAGKALTRSGAQPGDLLCVGGE
LGNAAGALPLVLGQRDAEPHIAQPLLDHYWSPQPQLALGQALRGKATSALDISDGLLADCGHIALASKVRLEVERERVPL
SEALVAFLGQRGAERAALSGGDDYVLAFTLPSVELPALLADSWSIHVIGRVTQGQGVVLLDRDGHDITPQIRGYQHFQES
P

Sequences:

>Translated_321_residues
MGEFELIRNFFAAAPCAQGGEGVALGIGDDCALLAVPSGEQLAVSTDTLVAGVHFADPCDPFLLGQRSLAVAVSDLAAMG
ATPVAFTLALTLPTVTADWLQAYARGLNRMAQGCGVALVGGDTTRGPLSLTVTVFGRVPAGKALTRSGAQPGDLLCVGGE
LGNAAGALPLVLGQRDAEPHIAQPLLDHYWSPQPQLALGQALRGKATSALDISDGLLADCGHIALASKVRLEVERERVPL
SEALVAFLGQRGAERAALSGGDDYVLAFTLPSVELPALLADSWSIHVIGRVTQGQGVVLLDRDGHDITPQIRGYQHFQES
P
>Mature_320_residues
GEFELIRNFFAAAPCAQGGEGVALGIGDDCALLAVPSGEQLAVSTDTLVAGVHFADPCDPFLLGQRSLAVAVSDLAAMGA
TPVAFTLALTLPTVTADWLQAYARGLNRMAQGCGVALVGGDTTRGPLSLTVTVFGRVPAGKALTRSGAQPGDLLCVGGEL
GNAAGALPLVLGQRDAEPHIAQPLLDHYWSPQPQLALGQALRGKATSALDISDGLLADCGHIALASKVRLEVERERVPLS
EALVAFLGQRGAERAALSGGDDYVLAFTLPSVELPALLADSWSIHVIGRVTQGQGVVLLDRDGHDITPQIRGYQHFQESP

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=321, Percent_Identity=44.2367601246106, Blast_Score=234, Evalue=5e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 33238; Mature: 33107

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEFELIRNFFAAAPCAQGGEGVALGIGDDCALLAVPSGEQLAVSTDTLVAGVHFADPCD
CCHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEECCCCEEEEECCCEEEEEECCCCCC
PFLLGQRSLAVAVSDLAAMGATPVAFTLALTLPTVTADWLQAYARGLNRMAQGCGVALVG
HHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEC
GDTTRGPLSLTVTVFGRVPAGKALTRSGAQPGDLLCVGGELGNAAGALPLVLGQRDAEPH
CCCCCCCEEEEEEEEECCCCCHHHHHCCCCCCCEEEECCCCCCCCCCCEEEECCCCCCCH
IAQPLLDHYWSPQPQLALGQALRGKATSALDISDGLLADCGHIALASKVRLEVERERVPL
HHHHHHHHHCCCCCCHHHHHHHCCCCCCEEECCCCCHHCCCHHHHHHHHEEEEHHHCCCH
SEALVAFLGQRGAERAALSGGDDYVLAFTLPSVELPALLADSWSIHVIGRVTQGQGVVLL
HHHHHHHHHCCCCCHHCCCCCCCEEEEEEECCCCCCCEEECCEEEEEEEEEECCCCEEEE
DRDGHDITPQIRGYQHFQESP
ECCCCCCCCCCCCCCHHCCCC
>Mature Secondary Structure 
GEFELIRNFFAAAPCAQGGEGVALGIGDDCALLAVPSGEQLAVSTDTLVAGVHFADPCD
CHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEECCCCEEEEECCCEEEEEECCCCCC
PFLLGQRSLAVAVSDLAAMGATPVAFTLALTLPTVTADWLQAYARGLNRMAQGCGVALVG
HHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEC
GDTTRGPLSLTVTVFGRVPAGKALTRSGAQPGDLLCVGGELGNAAGALPLVLGQRDAEPH
CCCCCCCEEEEEEEEECCCCCHHHHHCCCCCCCEEEECCCCCCCCCCCEEEECCCCCCCH
IAQPLLDHYWSPQPQLALGQALRGKATSALDISDGLLADCGHIALASKVRLEVERERVPL
HHHHHHHHHCCCCCCHHHHHHHCCCCCCEEECCCCCHHCCCHHHHHHHHEEEEHHHCCCH
SEALVAFLGQRGAERAALSGGDDYVLAFTLPSVELPALLADSWSIHVIGRVTQGQGVVLL
HHHHHHHHHCCCCCHHCCCCCCCEEEEEEECCCCCCCEEECCEEEEEEEEEECCCCEEEE
DRDGHDITPQIRGYQHFQESP
ECCCCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]