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The map label for this gene is acoR [H]

Identifier: 77461209

GI number: 77461209

Start: 5617831

End: 5619747

Strand: Reverse

Name: acoR [H]

Synonym: Pfl01_4988

Alternate gene names: 77461209

Gene position: 5619747-5617831 (Counterclockwise)

Preceding gene: 77461219

Following gene: 77461208

Centisome position: 87.28

GC content: 63.07

Gene sequence:

>1917_bases
ATGCACGACAACCATTTGAGTCGCCATGCCCAACAGGTTCTCACCGTCACCCAGGGCAAGCCGCACCTGCATGGCCCCGG
TGCCGACCCGTCGATTGCCCGCTCGTGGCTGCGTTGTCTTGAGGACTATCACCTCGACCCGGCCCTGACCATGGCGCCGA
CCGTGCTAGAACACGGTCGTGTCCTCGAAAGCCGCGAACGGCTGCAACAGGTGTTGCAGATCGCCGGCAATGAAATGAGC
AGCCTGCATCAACAACTCTCCGGCGCCGGCCATGCGGTACTGCTGACCGACGCACGCGGGGTGATCCTCAACTGCGTCAC
CGCCCCCGCCGAACGCAAGATTTTCGAACGCGCCGGCCTGTGGCTGGGCTCCGACTGGAGCGAGGCCTGCGAGGGCACCA
ACGGGATCGGCACTTGCCTCGTTGAACGTCAGGCCCTGACGATTCATCAGGATGAACACTTTCGCGGCCGCCATACCGGC
CTGACCTGCTCGGCGAGCCCGGTGTTCGACCCGCACGGCGAACTGCTGGCGGTGCTTGATGTTTCCTCGGCCCGGCCTGA
CGTCTCGCGGCAGAGCCAGTTCCACACCATGGCGCTGGTCAATTTGTCGGCGAAGATGATCGAGAGCTGCTATTTCCTGC
GCTGTTTCGATAACCAATGGTTGCTGCGTTTCCATCTCCAGGCCGAGTCCGTCGGGCTGTTCAGCGAAGGGTTGCTGGCG
TTTGACGGGGAAGGGCGGATCAGTGCGGTCAATCAGAGTGCCTTGAACCTGCTCGGCCATATTCGCGGTGGTTTGCTGGG
CAAACCGGTGGAGGCGTTTTTCGATTGTTCGCTGGATGAGTTGCTCGGGCGCGCCAGTGCCAATGCCAGTGCCAGTTGGC
CGTTGCGTACTCGTGACGGACGGCATCTGTTTGCGGTGCTGCGTGGCGAAACTCGCCGGCCGCTGCCGGTCGCGCCGGCT
CACGCGCCTGTGGAAGCGCCGCGTCTTGCAGGCATTTGCCTCGGTGATGCGACGTTGCAGGCGGATTTCCGCAAGTCGCT
GCGGGTATTCGAGCGCGACGTGCCGCTGCTGATCAACGGTGAAACAGGCTCCGGCAAAGAAGCATTCGCCAAGGCTGTGC
ACAACGCCAGTCAGCGCGCCGGCAAAGCCTTCGTTGCCCTCAACTGCGCGGCGATTCCCGAAAGCCTGATCGAGAGCGAA
CTGTTCGGCTATCGCGGCGGCAGCTTCACCGGCGCGCGCAAGGACGGTATGCGCGGCAAGTTGCAGCAGGCCGATGGCGG
CACGCTGTTCCTCGATGAAATCGGCGACATGCCGCTGGCTCTGCAAACCCGTCTGCTGCGGGTGCTGGAAGACCGGCAAG
TGGTGCCGATTGGCGGCGAGCCGGAAGCGGTCAACGTGCGGATCATCAGCGCCACCCACCGCAATCTGCTGGAACGGGTC
GGCGATGGCAGTTTCCGTGAAGACCTTTACTACCGGCTCAACGGGCTGGAAGTGGCGCTGCCACCATTGCGCGAGCGCAG
TGACAAATCGCAGCTGCTCGATTTTCTGCTGGCCGAAGAGGCGGGCGGGGAAACGATTCTGATCGAAGAACCGGCGCGCC
AGGCGTTGCTGCGGTTCAACTGGCCGGGCAATGTGCGGCAGTTGCGCAATGTGCTGCGCACGCTGGCGGCGTTGTGCGAT
GAAGGGCGGATCGGGCTGGATGATCTGCCCGCGATGTTTCGGCAGGTTCAGCCACTGTTGGTAAAAGCCGATGAAGCGTC
ATCCGCACAACCGCTGGAAGATGCCGAGCGACTGGCGTTGCTCAATGCGCTGGAACACTCGCGCTGGCACATGACCCTCA
CGGCGCAGCAACTGGGCGTCAGCCGCAATACGCTATATAGAAAGCTGCGCAAGCACGGGATCGCCCGAACCGCCTGA

Upstream 100 bases:

>100_bases
GACCGGGCGGTCTTGCCAGCATTGCAAAGACCGGTTGGCTGGAGGATGCTGGGCACCACTTCACGCATGGGCCGATGAGC
CTCGGGGAGAATAATAAGAA

Downstream 100 bases:

>100_bases
ATACTCCTGCCGATCGTTCCCACGCGGAGCGTGGGAACGATCAAGGCCTCCTCCCTCAATCAGCTAAAGAGTGCGATTTC
CCCCTCCCTGCGCTACCCTG

Product: sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 638; Mature: 638

Protein sequence:

>638_residues
MHDNHLSRHAQQVLTVTQGKPHLHGPGADPSIARSWLRCLEDYHLDPALTMAPTVLEHGRVLESRERLQQVLQIAGNEMS
SLHQQLSGAGHAVLLTDARGVILNCVTAPAERKIFERAGLWLGSDWSEACEGTNGIGTCLVERQALTIHQDEHFRGRHTG
LTCSASPVFDPHGELLAVLDVSSARPDVSRQSQFHTMALVNLSAKMIESCYFLRCFDNQWLLRFHLQAESVGLFSEGLLA
FDGEGRISAVNQSALNLLGHIRGGLLGKPVEAFFDCSLDELLGRASANASASWPLRTRDGRHLFAVLRGETRRPLPVAPA
HAPVEAPRLAGICLGDATLQADFRKSLRVFERDVPLLINGETGSGKEAFAKAVHNASQRAGKAFVALNCAAIPESLIESE
LFGYRGGSFTGARKDGMRGKLQQADGGTLFLDEIGDMPLALQTRLLRVLEDRQVVPIGGEPEAVNVRIISATHRNLLERV
GDGSFREDLYYRLNGLEVALPPLRERSDKSQLLDFLLAEEAGGETILIEEPARQALLRFNWPGNVRQLRNVLRTLAALCD
EGRIGLDDLPAMFRQVQPLLVKADEASSAQPLEDAERLALLNALEHSRWHMTLTAQQLGVSRNTLYRKLRKHGIARTA

Sequences:

>Translated_638_residues
MHDNHLSRHAQQVLTVTQGKPHLHGPGADPSIARSWLRCLEDYHLDPALTMAPTVLEHGRVLESRERLQQVLQIAGNEMS
SLHQQLSGAGHAVLLTDARGVILNCVTAPAERKIFERAGLWLGSDWSEACEGTNGIGTCLVERQALTIHQDEHFRGRHTG
LTCSASPVFDPHGELLAVLDVSSARPDVSRQSQFHTMALVNLSAKMIESCYFLRCFDNQWLLRFHLQAESVGLFSEGLLA
FDGEGRISAVNQSALNLLGHIRGGLLGKPVEAFFDCSLDELLGRASANASASWPLRTRDGRHLFAVLRGETRRPLPVAPA
HAPVEAPRLAGICLGDATLQADFRKSLRVFERDVPLLINGETGSGKEAFAKAVHNASQRAGKAFVALNCAAIPESLIESE
LFGYRGGSFTGARKDGMRGKLQQADGGTLFLDEIGDMPLALQTRLLRVLEDRQVVPIGGEPEAVNVRIISATHRNLLERV
GDGSFREDLYYRLNGLEVALPPLRERSDKSQLLDFLLAEEAGGETILIEEPARQALLRFNWPGNVRQLRNVLRTLAALCD
EGRIGLDDLPAMFRQVQPLLVKADEASSAQPLEDAERLALLNALEHSRWHMTLTAQQLGVSRNTLYRKLRKHGIARTA
>Mature_638_residues
MHDNHLSRHAQQVLTVTQGKPHLHGPGADPSIARSWLRCLEDYHLDPALTMAPTVLEHGRVLESRERLQQVLQIAGNEMS
SLHQQLSGAGHAVLLTDARGVILNCVTAPAERKIFERAGLWLGSDWSEACEGTNGIGTCLVERQALTIHQDEHFRGRHTG
LTCSASPVFDPHGELLAVLDVSSARPDVSRQSQFHTMALVNLSAKMIESCYFLRCFDNQWLLRFHLQAESVGLFSEGLLA
FDGEGRISAVNQSALNLLGHIRGGLLGKPVEAFFDCSLDELLGRASANASASWPLRTRDGRHLFAVLRGETRRPLPVAPA
HAPVEAPRLAGICLGDATLQADFRKSLRVFERDVPLLINGETGSGKEAFAKAVHNASQRAGKAFVALNCAAIPESLIESE
LFGYRGGSFTGARKDGMRGKLQQADGGTLFLDEIGDMPLALQTRLLRVLEDRQVVPIGGEPEAVNVRIISATHRNLLERV
GDGSFREDLYYRLNGLEVALPPLRERSDKSQLLDFLLAEEAGGETILIEEPARQALLRFNWPGNVRQLRNVLRTLAALCD
EGRIGLDDLPAMFRQVQPLLVKADEASSAQPLEDAERLALLNALEHSRWHMTLTAQQLGVSRNTLYRKLRKHGIARTA

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=439, Percent_Identity=35.7630979498861, Blast_Score=244, Evalue=1e-65,
Organism=Escherichia coli, GI1790299, Length=332, Percent_Identity=47.5903614457831, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI1788550, Length=327, Percent_Identity=38.8379204892966, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1786524, Length=319, Percent_Identity=42.6332288401254, Blast_Score=208, Evalue=9e-55,
Organism=Escherichia coli, GI1788905, Length=289, Percent_Identity=43.2525951557093, Blast_Score=208, Evalue=1e-54,
Organism=Escherichia coli, GI1790437, Length=282, Percent_Identity=42.5531914893617, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI87082117, Length=329, Percent_Identity=39.8176291793313, Blast_Score=194, Evalue=2e-50,
Organism=Escherichia coli, GI1789087, Length=299, Percent_Identity=39.1304347826087, Blast_Score=181, Evalue=2e-46,
Organism=Escherichia coli, GI1787583, Length=289, Percent_Identity=39.7923875432526, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI87082152, Length=218, Percent_Identity=45.8715596330275, Blast_Score=174, Evalue=2e-44,
Organism=Escherichia coli, GI87081872, Length=298, Percent_Identity=37.5838926174497, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI87081858, Length=650, Percent_Identity=25.3846153846154, Blast_Score=153, Evalue=3e-38,
Organism=Escherichia coli, GI1789828, Length=317, Percent_Identity=32.1766561514196, Blast_Score=133, Evalue=4e-32,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 70115; Mature: 70115

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHDNHLSRHAQQVLTVTQGKPHLHGPGADPSIARSWLRCLEDYHLDPALTMAPTVLEHGR
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCH
VLESRERLQQVLQIAGNEMSSLHQQLSGAGHAVLLTDARGVILNCVTAPAERKIFERAGL
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCHHHHHHHHHCC
WLGSDWSEACEGTNGIGTCLVERQALTIHQDEHFRGRHTGLTCSASPVFDPHGELLAVLD
CCCCCHHHHHCCCCCCEEEEEECCEEEEECCCCCCCCCCCEEECCCCCCCCCCCEEEEEE
VSSARPDVSRQSQFHTMALVNLSAKMIESCYFLRCFDNQWLLRFHLQAESVGLFSEGLLA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCEEEEEEEEHHCCCHHHCCCEE
FDGEGRISAVNQSALNLLGHIRGGLLGKPVEAFFDCSLDELLGRASANASASWPLRTRDG
ECCCCCEEHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHCCCCCCCCCCEECCCC
RHLFAVLRGETRRPLPVAPAHAPVEAPRLAGICLGDATLQADFRKSLRVFERDVPLLING
CEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCEEEEC
ETGSGKEAFAKAVHNASQRAGKAFVALNCAAIPESLIESELFGYRGGSFTGARKDGMRGK
CCCCCHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
LQQADGGTLFLDEIGDMPLALQTRLLRVLEDRQVVPIGGEPEAVNVRIISATHRNLLERV
CEECCCCEEEHHHHCCCCHHHHHHHHHHHCCCCEEECCCCCCEEEEEEEEHHHHHHHHHH
GDGSFREDLYYRLNGLEVALPPLRERSDKSQLLDFLLAEEAGGETILIEEPARQALLRFN
CCCCHHHHHHHEECCCEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCHHHCEEEEC
WPGNVRQLRNVLRTLAALCDEGRIGLDDLPAMFRQVQPLLVKADEASSAQPLEDAERLAL
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHEEEECCCCCCCCHHHHHHHHH
LNALEHSRWHMTLTAQQLGVSRNTLYRKLRKHGIARTA
HHHHHCCCEEEEEEHHHHCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MHDNHLSRHAQQVLTVTQGKPHLHGPGADPSIARSWLRCLEDYHLDPALTMAPTVLEHGR
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCH
VLESRERLQQVLQIAGNEMSSLHQQLSGAGHAVLLTDARGVILNCVTAPAERKIFERAGL
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCHHHHHHHHHCC
WLGSDWSEACEGTNGIGTCLVERQALTIHQDEHFRGRHTGLTCSASPVFDPHGELLAVLD
CCCCCHHHHHCCCCCCEEEEEECCEEEEECCCCCCCCCCCEEECCCCCCCCCCCEEEEEE
VSSARPDVSRQSQFHTMALVNLSAKMIESCYFLRCFDNQWLLRFHLQAESVGLFSEGLLA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCEEEEEEEEHHCCCHHHCCCEE
FDGEGRISAVNQSALNLLGHIRGGLLGKPVEAFFDCSLDELLGRASANASASWPLRTRDG
ECCCCCEEHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHCCCCCCCCCCEECCCC
RHLFAVLRGETRRPLPVAPAHAPVEAPRLAGICLGDATLQADFRKSLRVFERDVPLLING
CEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCEEEEC
ETGSGKEAFAKAVHNASQRAGKAFVALNCAAIPESLIESELFGYRGGSFTGARKDGMRGK
CCCCCHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
LQQADGGTLFLDEIGDMPLALQTRLLRVLEDRQVVPIGGEPEAVNVRIISATHRNLLERV
CEECCCCEEEHHHHCCCCHHHHHHHHHHHCCCCEEECCCCCCEEEEEEEEHHHHHHHHHH
GDGSFREDLYYRLNGLEVALPPLRERSDKSQLLDFLLAEEAGGETILIEEPARQALLRFN
CCCCHHHHHHHEECCCEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCHHHCEEEEC
WPGNVRQLRNVLRTLAALCDEGRIGLDDLPAMFRQVQPLLVKADEASSAQPLEDAERLAL
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHEEEECCCCCCCCHHHHHHHHH
LNALEHSRWHMTLTAQQLGVSRNTLYRKLRKHGIARTA
HHHHHCCCEEEEEEHHHHCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]