Click here to switch to the map view.

The map label for this gene is aidB [H]

Identifier: 77461164

GI number: 77461164

Start: 5569007

End: 5570656

Strand: Reverse

Name: aidB [H]

Synonym: Pfl01_4943

Alternate gene names: 77461164

Gene position: 5570656-5569007 (Counterclockwise)

Preceding gene: 77461165

Following gene: 77461163

Centisome position: 86.52

GC content: 63.09

Gene sequence:

>1650_bases
ATGAACCTGCATCAGTTCGCCGAAACCCACGAAGTCACCAACCAGCCACCGTCGCTGGACGGCACCAACCTGTACCGCAT
TGATCTGCCATTGCAGGAGTGGTCGCGGCGGTTCGGCGCTGGCTGGGCCGAGTCGCGGATCGATGCCTACGGCGCGCTGG
CCGGCGGGCCGCTGATGGAGGCCGGGTTCCTTGCCAACCAGAACAAACCGGTATTTGCCAGCCATGACCGCTACGGTCAT
CGCATCGATCTGGTGGAGTTTCATCCGGCGTATCACGAGCTGATGCGCACTGCCATTGAACATGGCCTGACGTCGTTGCC
CTGGGCTCATCCACAGGACGGCGCCCATGTCGCCCGCGCTTCCATGAGCTATCTGCACAGTCAGGCCGAGGCCGGCAGTG
GTTGCCCGCTGACCATGACCTTCGCCAGCGTTCCGGCGATGCGTTTGCAGCCGAATCTGGCCGAGCATTGGCTGCCGAAA
ATCCTCGCCACCGAATACGACCCGCGCAATGTCGGCATGGCCCACAAGGCCGGCGTCACCATCGGCATGGCGATGACCGA
GAAACAGGGCGGCACCGACGTGCGTGCCAACACCACCAAGGCTTATCCGGTCGGCGCCAGTGGCCCGGGCCAGGCCTATG
AACTGGTGGGGCACAAGTGGTTCTGTTCGGCGCCGATGTGCGATGCGTTCCTGACGCTGGCGCAAACCGACAAGGGCTTG
AGCTGCTTCCTGCTGCCGCGCCATCGCCCGGACGACACGCGCAATCAGTTCTACATCCAGCGCCTGAAAAACAAACTCGG
TAACCAGTCCAACGCCTCCAGCGAAGTGGAGTTCCGTGGTGCGCTGGCGTGGATGGTCGGTGAGGAAGGGCGCGGCGTGC
CGACCATCATCGAGATGGTGGCGATGACCCGTTTCGATTGCATGGTCGGCTCCAGCTCGCTGATGCGTCAGGCGCTGACC
CAGGCCAGCCATCACTGCGCCCATCGCAAGGTCGGTGGCAAACTGCTCAGTGAACAACCGCTGATGCAGAATGTGCTGGC
CGATCTGGCGCTGGAAAGCGAAGCCGCGCTGGCGCTGAGCCTGCGCATGGGCAAGGCGCTGGATCATCTCGATGACCGCC
ATGAAGCGCAGTTCGCCCGGTTGGTGACAGCGGTGGGCAAGTACTGGATCTGCAAACGCGCGCCGGCAATGATCAACGAA
GCCGCCGAATGCATGGGCGGCGCCGGGTATGTCGAAGACAGCATCCTGCCGCGTTTGTACCGCGAGGCGCCGGTGAACTC
GACGTGGGAAGGCTCCGGCAATGTGCAATGCCTCGACGTGTTGCGCGCCTTGTCGAAAGAGCCGGGCGTGCTCGATGTGT
TGTTCAGCGAGTTGGGCGACGGCCATGGCGACAAGCGACTGGCCGCGCACATTCAGCAATTGCAGGCGCAGTTCAAGGAC
ACCAGTGACATTCAGTACCGCGCTCGGCAACTGACCGAAGACATCGCTTTGGGACTGCAAGCGAAGCTGCTGCTGGAGGC
CGGGAATTCTGCGGTCAGCGATGCTTTTATCGCCAGTCGCCTGAGCGGTGGCGGCCGGGTCTACGGCGCGTTGCCGCGCG
GGTTGGATGTCGAAGCCATCGTCGCTCGCTCCACACCACAAGGTTTCTGA

Upstream 100 bases:

>100_bases
GCTGACAGGGTGAAAGCGCCGGCATTTCGGCCGATATGACACTTTGATCGGTTCCGGTGCGGTGCTTAACTGAAGCTCTG
GCCGATCAAGGAGCCCCGTC

Downstream 100 bases:

>100_bases
AGGGGGATCGCGACAAAGCCATTACGCCACTGTTTCCGTGACGCCACGATGCAGGCAAGATGAAGCTCTGCAAGTCAGAA
CACAGGAAGCTGATCGTGAC

Product: acyl-CoA dehydrogenase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MNLHQFAETHEVTNQPPSLDGTNLYRIDLPLQEWSRRFGAGWAESRIDAYGALAGGPLMEAGFLANQNKPVFASHDRYGH
RIDLVEFHPAYHELMRTAIEHGLTSLPWAHPQDGAHVARASMSYLHSQAEAGSGCPLTMTFASVPAMRLQPNLAEHWLPK
ILATEYDPRNVGMAHKAGVTIGMAMTEKQGGTDVRANTTKAYPVGASGPGQAYELVGHKWFCSAPMCDAFLTLAQTDKGL
SCFLLPRHRPDDTRNQFYIQRLKNKLGNQSNASSEVEFRGALAWMVGEEGRGVPTIIEMVAMTRFDCMVGSSSLMRQALT
QASHHCAHRKVGGKLLSEQPLMQNVLADLALESEAALALSLRMGKALDHLDDRHEAQFARLVTAVGKYWICKRAPAMINE
AAECMGGAGYVEDSILPRLYREAPVNSTWEGSGNVQCLDVLRALSKEPGVLDVLFSELGDGHGDKRLAAHIQQLQAQFKD
TSDIQYRARQLTEDIALGLQAKLLLEAGNSAVSDAFIASRLSGGGRVYGALPRGLDVEAIVARSTPQGF

Sequences:

>Translated_549_residues
MNLHQFAETHEVTNQPPSLDGTNLYRIDLPLQEWSRRFGAGWAESRIDAYGALAGGPLMEAGFLANQNKPVFASHDRYGH
RIDLVEFHPAYHELMRTAIEHGLTSLPWAHPQDGAHVARASMSYLHSQAEAGSGCPLTMTFASVPAMRLQPNLAEHWLPK
ILATEYDPRNVGMAHKAGVTIGMAMTEKQGGTDVRANTTKAYPVGASGPGQAYELVGHKWFCSAPMCDAFLTLAQTDKGL
SCFLLPRHRPDDTRNQFYIQRLKNKLGNQSNASSEVEFRGALAWMVGEEGRGVPTIIEMVAMTRFDCMVGSSSLMRQALT
QASHHCAHRKVGGKLLSEQPLMQNVLADLALESEAALALSLRMGKALDHLDDRHEAQFARLVTAVGKYWICKRAPAMINE
AAECMGGAGYVEDSILPRLYREAPVNSTWEGSGNVQCLDVLRALSKEPGVLDVLFSELGDGHGDKRLAAHIQQLQAQFKD
TSDIQYRARQLTEDIALGLQAKLLLEAGNSAVSDAFIASRLSGGGRVYGALPRGLDVEAIVARSTPQGF
>Mature_549_residues
MNLHQFAETHEVTNQPPSLDGTNLYRIDLPLQEWSRRFGAGWAESRIDAYGALAGGPLMEAGFLANQNKPVFASHDRYGH
RIDLVEFHPAYHELMRTAIEHGLTSLPWAHPQDGAHVARASMSYLHSQAEAGSGCPLTMTFASVPAMRLQPNLAEHWLPK
ILATEYDPRNVGMAHKAGVTIGMAMTEKQGGTDVRANTTKAYPVGASGPGQAYELVGHKWFCSAPMCDAFLTLAQTDKGL
SCFLLPRHRPDDTRNQFYIQRLKNKLGNQSNASSEVEFRGALAWMVGEEGRGVPTIIEMVAMTRFDCMVGSSSLMRQALT
QASHHCAHRKVGGKLLSEQPLMQNVLADLALESEAALALSLRMGKALDHLDDRHEAQFARLVTAVGKYWICKRAPAMINE
AAECMGGAGYVEDSILPRLYREAPVNSTWEGSGNVQCLDVLRALSKEPGVLDVLFSELGDGHGDKRLAAHIQQLQAQFKD
TSDIQYRARQLTEDIALGLQAKLLLEAGNSAVSDAFIASRLSGGGRVYGALPRGLDVEAIVARSTPQGF

Specific function: May help to prevent alkylation damage by protecting DNA and destroying alkylating agents [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=275, Percent_Identity=27.6363636363636, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI226958412, Length=305, Percent_Identity=24.2622950819672, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI226958414, Length=305, Percent_Identity=24.2622950819672, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4501859, Length=275, Percent_Identity=25.0909090909091, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI87082384, Length=502, Percent_Identity=45.4183266932271, Blast_Score=410, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI86563381, Length=532, Percent_Identity=30.8270676691729, Blast_Score=186, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI86563383, Length=532, Percent_Identity=30.8270676691729, Blast_Score=186, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17538396, Length=302, Percent_Identity=24.1721854304636, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17508101, Length=274, Percent_Identity=22.992700729927, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281363737, Length=348, Percent_Identity=23.2758620689655, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21356377, Length=275, Percent_Identity=24.7272727272727, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21355753, Length=308, Percent_Identity=23.3766233766234, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M [H]

EC number: NA

Molecular weight: Translated: 59910; Mature: 59910

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHQFAETHEVTNQPPSLDGTNLYRIDLPLQEWSRRFGAGWAESRIDAYGALAGGPLME
CCHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHCCCHHHHHHHHHHHCCCCCHHH
AGFLANQNKPVFASHDRYGHRIDLVEFHPAYHELMRTAIEHGLTSLPWAHPQDGAHVARA
HCHHCCCCCCEEECCCCCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
SMSYLHSQAEAGSGCPLTMTFASVPAMRLQPNLAEHWLPKILATEYDPRNVGMAHKAGVT
HHHHHHHHHCCCCCCCEEEHHHHCCHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHCCCE
IGMAMTEKQGGTDVRANTTKAYPVGASGPGQAYELVGHKWFCSAPMCDAFLTLAQTDKGL
EEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCEECCCCHHHHHHHHHHCCCCC
SCFLLPRHRPDDTRNQFYIQRLKNKLGNQSNASSEVEFRGALAWMVGEEGRGVPTIIEMV
EEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEHHEEEEEEECCCCCCHHHHHHHH
AMTRFDCMVGSSSLMRQALTQASHHCAHRKVGGKLLSEQPLMQNVLADLALESEAALALS
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCCHHHHHH
LRMGKALDHLDDRHEAQFARLVTAVGKYWICKRAPAMINEAAECMGGAGYVEDSILPRLY
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHH
REAPVNSTWEGSGNVQCLDVLRALSKEPGVLDVLFSELGDGHGDKRLAAHIQQLQAQFKD
HHCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC
TSDIQYRARQLTEDIALGLQAKLLLEAGNSAVSDAFIASRLSGGGRVYGALPRGLDVEAI
CCHHHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCEEE
VARSTPQGF
EECCCCCCC
>Mature Secondary Structure
MNLHQFAETHEVTNQPPSLDGTNLYRIDLPLQEWSRRFGAGWAESRIDAYGALAGGPLME
CCHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHCCCHHHHHHHHHHHCCCCCHHH
AGFLANQNKPVFASHDRYGHRIDLVEFHPAYHELMRTAIEHGLTSLPWAHPQDGAHVARA
HCHHCCCCCCEEECCCCCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
SMSYLHSQAEAGSGCPLTMTFASVPAMRLQPNLAEHWLPKILATEYDPRNVGMAHKAGVT
HHHHHHHHHCCCCCCCEEEHHHHCCHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHCCCE
IGMAMTEKQGGTDVRANTTKAYPVGASGPGQAYELVGHKWFCSAPMCDAFLTLAQTDKGL
EEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCEECCCCHHHHHHHHHHCCCCC
SCFLLPRHRPDDTRNQFYIQRLKNKLGNQSNASSEVEFRGALAWMVGEEGRGVPTIIEMV
EEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEHHEEEEEEECCCCCCHHHHHHHH
AMTRFDCMVGSSSLMRQALTQASHHCAHRKVGGKLLSEQPLMQNVLADLALESEAALALS
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCCHHHHHH
LRMGKALDHLDDRHEAQFARLVTAVGKYWICKRAPAMINEAAECMGGAGYVEDSILPRLY
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHH
REAPVNSTWEGSGNVQCLDVLRALSKEPGVLDVLFSELGDGHGDKRLAAHIQQLQAQFKD
HHCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC
TSDIQYRARQLTEDIALGLQAKLLLEAGNSAVSDAFIASRLSGGGRVYGALPRGLDVEAI
CCHHHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCEEE
VARSTPQGF
EECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961409; 7610040; 9278503 [H]