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The map label for this gene is tesB [H]

Identifier: 77461137

GI number: 77461137

Start: 5539216

End: 5540085

Strand: Reverse

Name: tesB [H]

Synonym: Pfl01_4916

Alternate gene names: 77461137

Gene position: 5540085-5539216 (Counterclockwise)

Preceding gene: 77461138

Following gene: 77461136

Centisome position: 86.05

GC content: 62.64

Gene sequence:

>870_bases
ATGAGCCAAGTGTTGGAAGATCTGGTGGATCTGCTGACCCTCGAACCGATCGAGGAAAACCTGTTCCGTGGTCGCAGCCA
GGATCTGGGCTTTCGCCAGTTGTTCGGCGGCCAGGTGCTCGGCCAGTCGCTGTCGGCGGCCAGTCAGACCGTTGAAGAAG
CGCGCCATGTGCATTCGATGCACGGTTATTTCCTGCGTCCGGGCGATGCCAAGTTGCCGGTGGTCTACTCGGTGGACCGC
GTGCGCGACGGCGGCAGTTTCAGCACCCGCCGCGTGACCGCGATCCAGAAGGGCCACCCGATTTTTACCTGCAGCGCTTC
GTTTCAGTACGACGAAGAAGGCTTCGAACACCAGAGCCAGATGCCGCAAGTGGTCGGCCCGGAAAACCTGCCGTCGGAGC
TGGAACTGACCCAGCAACGCGCGCACCTGATCCCGGAACACATGCGCGAAAAGCTGCTGTGCCCGAAGCCGATCGAAGTG
CGCCCGGTCACCGAAAAAGACCCGTACAACCCGCAACCGGCGGATCCGGTCAAGTACGTGTGGTTCCGTGCCGACGGCGC
GTTGGCCGACATCCCGGCGCTGCACAAATACCTGCTGGCCTACGCCTCGGACTTCGGTCTGCTGACCACCTCGATGCTGC
CGCATGGCAAATCGGTCTGGCAGAAAGACATGCAGGTCGCCAGCCTCGACCACGCTTTGTGGTTCCACAACGACCTGCGC
GCCGATGACTGGTTGCTCTACGCCATGGACAGCCCGTGGGCCGGCAATTCGCGTGGATTCTCCCGTGGCAGCGTGTTCAA
CCGTGCCGGGCAACTGGTGGCGTCGGTGACCCAGGAAGGCCTGATCCGCCATCGCAAGGACTGGGCATGA

Upstream 100 bases:

>100_bases
ACGGACGTTTACAATGGCGCGATCAGTGGCTCGCGCCAGAATCTGAATTGGCCGTCGCAGCCAGGACTGCGCGGCATAGC
GTTGTGTGAGGAGAGTCTGA

Downstream 100 bases:

>100_bases
GTCTGGCGGAAGTGCGGCACTGGGTGTTCGACATGGACGGCACCCTGACCGTCGCCGTGCACGACTTCGCGGCGATTCGC
GTGGCGCTGGCGATCCCGCC

Product: palmitoyl-CoA hydrolase

Products: Hydrolyzed acyl-CoA thioesters [C]

Alternate protein names: Acyl-CoA thioesterase II; TEII [H]

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MSQVLEDLVDLLTLEPIEENLFRGRSQDLGFRQLFGGQVLGQSLSAASQTVEEARHVHSMHGYFLRPGDAKLPVVYSVDR
VRDGGSFSTRRVTAIQKGHPIFTCSASFQYDEEGFEHQSQMPQVVGPENLPSELELTQQRAHLIPEHMREKLLCPKPIEV
RPVTEKDPYNPQPADPVKYVWFRADGALADIPALHKYLLAYASDFGLLTTSMLPHGKSVWQKDMQVASLDHALWFHNDLR
ADDWLLYAMDSPWAGNSRGFSRGSVFNRAGQLVASVTQEGLIRHRKDWA

Sequences:

>Translated_289_residues
MSQVLEDLVDLLTLEPIEENLFRGRSQDLGFRQLFGGQVLGQSLSAASQTVEEARHVHSMHGYFLRPGDAKLPVVYSVDR
VRDGGSFSTRRVTAIQKGHPIFTCSASFQYDEEGFEHQSQMPQVVGPENLPSELELTQQRAHLIPEHMREKLLCPKPIEV
RPVTEKDPYNPQPADPVKYVWFRADGALADIPALHKYLLAYASDFGLLTTSMLPHGKSVWQKDMQVASLDHALWFHNDLR
ADDWLLYAMDSPWAGNSRGFSRGSVFNRAGQLVASVTQEGLIRHRKDWA
>Mature_288_residues
SQVLEDLVDLLTLEPIEENLFRGRSQDLGFRQLFGGQVLGQSLSAASQTVEEARHVHSMHGYFLRPGDAKLPVVYSVDRV
RDGGSFSTRRVTAIQKGHPIFTCSASFQYDEEGFEHQSQMPQVVGPENLPSELELTQQRAHLIPEHMREKLLCPKPIEVR
PVTEKDPYNPQPADPVKYVWFRADGALADIPALHKYLLAYASDFGLLTTSMLPHGKSVWQKDMQVASLDHALWFHNDLRA
DDWLLYAMDSPWAGNSRGFSRGSVFNRAGQLVASVTQEGLIRHRKDWA

Specific function: Can hydrolyze a broad range of acyl-CoA thioesters. Its physiological function is not known [H]

COG id: COG1946

COG function: function code I; Acyl-CoA thioesterase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C/M/P thioester hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI34577075, Length=285, Percent_Identity=42.4561403508772, Blast_Score=218, Evalue=3e-57,
Organism=Escherichia coli, GI1786657, Length=284, Percent_Identity=51.056338028169, Blast_Score=299, Evalue=1e-82,
Organism=Caenorhabditis elegans, GI71988741, Length=296, Percent_Identity=38.1756756756757, Blast_Score=193, Evalue=7e-50,
Organism=Caenorhabditis elegans, GI17558508, Length=308, Percent_Identity=37.6623376623377, Blast_Score=179, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17531889, Length=272, Percent_Identity=36.3970588235294, Blast_Score=158, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI115532456, Length=272, Percent_Identity=36.3970588235294, Blast_Score=158, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17531885, Length=272, Percent_Identity=36.3970588235294, Blast_Score=158, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI71982224, Length=301, Percent_Identity=30.5647840531561, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI212645202, Length=268, Percent_Identity=29.4776119402985, Blast_Score=111, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003703 [H]

Pfam domain/function: PF02551 Acyl_CoA_thio [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 32621; Mature: 32490

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQVLEDLVDLLTLEPIEENLFRGRSQDLGFRQLFGGQVLGQSLSAASQTVEEARHVHSM
CHHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGYFLRPGDAKLPVVYSVDRVRDGGSFSTRRVTAIQKGHPIFTCSASFQYDEEGFEHQSQ
CCEEECCCCCCCCEEEEHHHCCCCCCCCCEEEEEEECCCCEEEEECCCCCCHHHHHHHHC
MPQVVGPENLPSELELTQQRAHLIPEHMREKLLCPKPIEVRPVTEKDPYNPQPADPVKYV
CCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCEEEE
WFRADGALADIPALHKYLLAYASDFGLLTTSMLPHGKSVWQKDMQVASLDHALWFHNDLR
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCC
ADDWLLYAMDSPWAGNSRGFSRGSVFNRAGQLVASVTQEGLIRHRKDWA
CCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SQVLEDLVDLLTLEPIEENLFRGRSQDLGFRQLFGGQVLGQSLSAASQTVEEARHVHSM
HHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGYFLRPGDAKLPVVYSVDRVRDGGSFSTRRVTAIQKGHPIFTCSASFQYDEEGFEHQSQ
CCEEECCCCCCCCEEEEHHHCCCCCCCCCEEEEEEECCCCEEEEECCCCCCHHHHHHHHC
MPQVVGPENLPSELELTQQRAHLIPEHMREKLLCPKPIEVRPVTEKDPYNPQPADPVKYV
CCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCEEEE
WFRADGALADIPALHKYLLAYASDFGLLTTSMLPHGKSVWQKDMQVASLDHALWFHNDLR
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCC
ADDWLLYAMDSPWAGNSRGFSRGSVFNRAGQLVASVTQEGLIRHRKDWA
CCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA thioesters [C]

Specific reaction: Hydrolyzes a broad range of acyl-CoA thioesters [C]

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]