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The map label for this gene is uxuR [H]

Identifier: 77461100

GI number: 77461100

Start: 5503023

End: 5503727

Strand: Direct

Name: uxuR [H]

Synonym: Pfl01_4879

Alternate gene names: 77461100

Gene position: 5503023-5503727 (Clockwise)

Preceding gene: 77461099

Following gene: 77461101

Centisome position: 85.47

GC content: 62.55

Gene sequence:

>705_bases
GTGATTACTACATCAACCGTCGTCAACTCAGTGGTGGAAAAACTCCGGGCCGCGCTGGCCCGGGGTCAGTGGCGCTCCGG
CGAAATGCTGCCGGGCCAGCGTGAACTGGCCGAACAACTGGGTATCAGCCGCCCGAGCCTGCGTGAAGCGGTGATCGTGC
TGGAGACCCTTGGCCTGGTGCGCTCGATGCCCGGCAAAGGCGTGGTGGTCCTCGACGCCCAGACCAGTGACAACCAAAAC
CACGACAGCGCCGTGGCCGGCGCCAGCCTCGAAGACGTGCTGCAACTGCGCTACACCCTTGAACCGTTCATCGTTGGTCT
GGTGGCGCAGTCGATCAGCAGCAAGGAAGTCGGCCAGTTGCGCCTGACCCTGATGGACATGCGCGAAGCCCTCGAAGCGG
GTGACAGCGAGGCCGGCGTCAGCGCCTACATCGCCTTTCACGAAGAACTGTTCACCCTGACCTCGAACCCGATTTTCCAG
AGCGTGGTGCAACAGACCAGCAATGCCCTCAAGCAAAGCGCCGAAGTGCTGCGCAATTCACCGGAGCACCTGGCCGAACG
CCTTGAGGAAAACGAAGCCGTAGTACGCGCGATCCGCAGCAAGAACAGCGCCCAGGCCAGCGCCGAAATGCGCCGGCACA
TCCTGCGTGAAGGCCAGCGGATGGGCATCGAGCTGAATATCCCGGATGACAACCTGAGCCACTGA

Upstream 100 bases:

>100_bases
AACTTTCAGCCGAGAAAAACGGTCGCTCAAGCGGCGGCCAAAGAATTCTGAATGAGCGCCGTGCCTGCGCCAATGCAGGC
ACGGCTCATGGAGCGAACAC

Downstream 100 bases:

>100_bases
AACGCCTCACACTGGAGACCGGCCATGAACAGTCTTGCCACGCCGTCGCACCCTCGCCCGACCTCGGCGGCCCTGCCCTT
CTCCCGCCTGCAAGCGCCGG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MITTSTVVNSVVEKLRAALARGQWRSGEMLPGQRELAEQLGISRPSLREAVIVLETLGLVRSMPGKGVVVLDAQTSDNQN
HDSAVAGASLEDVLQLRYTLEPFIVGLVAQSISSKEVGQLRLTLMDMREALEAGDSEAGVSAYIAFHEELFTLTSNPIFQ
SVVQQTSNALKQSAEVLRNSPEHLAERLEENEAVVRAIRSKNSAQASAEMRRHILREGQRMGIELNIPDDNLSH

Sequences:

>Translated_234_residues
MITTSTVVNSVVEKLRAALARGQWRSGEMLPGQRELAEQLGISRPSLREAVIVLETLGLVRSMPGKGVVVLDAQTSDNQN
HDSAVAGASLEDVLQLRYTLEPFIVGLVAQSISSKEVGQLRLTLMDMREALEAGDSEAGVSAYIAFHEELFTLTSNPIFQ
SVVQQTSNALKQSAEVLRNSPEHLAERLEENEAVVRAIRSKNSAQASAEMRRHILREGQRMGIELNIPDDNLSH
>Mature_234_residues
MITTSTVVNSVVEKLRAALARGQWRSGEMLPGQRELAEQLGISRPSLREAVIVLETLGLVRSMPGKGVVVLDAQTSDNQN
HDSAVAGASLEDVLQLRYTLEPFIVGLVAQSISSKEVGQLRLTLMDMREALEAGDSEAGVSAYIAFHEELFTLTSNPIFQ
SVVQQTSNALKQSAEVLRNSPEHLAERLEENEAVVRAIRSKNSAQASAEMRRHILREGQRMGIELNIPDDNLSH

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=235, Percent_Identity=28.936170212766, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI48994961, Length=159, Percent_Identity=27.0440251572327, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 25623; Mature: 25623

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITTSTVVNSVVEKLRAALARGQWRSGEMLPGQRELAEQLGISRPSLREAVIVLETLGLV
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHH
RSMPGKGVVVLDAQTSDNQNHDSAVAGASLEDVLQLRYTLEPFIVGLVAQSISSKEVGQL
HCCCCCCEEEEECCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
RLTLMDMREALEAGDSEAGVSAYIAFHEELFTLTSNPIFQSVVQQTSNALKQSAEVLRNS
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
PEHLAERLEENEAVVRAIRSKNSAQASAEMRRHILREGQRMGIELNIPDDNLSH
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCC
>Mature Secondary Structure
MITTSTVVNSVVEKLRAALARGQWRSGEMLPGQRELAEQLGISRPSLREAVIVLETLGLV
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHH
RSMPGKGVVVLDAQTSDNQNHDSAVAGASLEDVLQLRYTLEPFIVGLVAQSISSKEVGQL
HCCCCCCEEEEECCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
RLTLMDMREALEAGDSEAGVSAYIAFHEELFTLTSNPIFQSVVQQTSNALKQSAEVLRNS
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
PEHLAERLEENEAVVRAIRSKNSAQASAEMRRHILREGQRMGIELNIPDDNLSH
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]