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The map label for this gene is obgE [H]

Identifier: 77461079

GI number: 77461079

Start: 5477922

End: 5479145

Strand: Reverse

Name: obgE [H]

Synonym: Pfl01_4858

Alternate gene names: 77461079

Gene position: 5479145-5477922 (Counterclockwise)

Preceding gene: 77461080

Following gene: 77461078

Centisome position: 85.1

GC content: 59.64

Gene sequence:

>1224_bases
ATGAAGTTTGTTGATGAAGTATCGATCCGCGTAAAGGCTGGTGACGGCGGCAATGGCTGCATGAGTTTCCGTCGGGAAAA
GTTCATTGAAAACGGCGGTCCGAACGGTGGTGACGGCGGTGATGGCGGTTCCATCTTCATGATGGCCGACGAAAACCTGA
ATACCCTGGTGGACTACCGTTACACCCGGCACTTCGATGCCGAGCGTGGCTCCAACGGCGGCAGCACCGACTGCACCGGC
AAGAAGGGTGAAGACCTGATCCTGCGCGTGCCGGTCGGCACCACCGTGATCGATTCCGCCACCCAGGAAGTCATTGGCGA
CCTGACCAAGGCTGGTCAGAAGCTGATGGTGGTTCAGGGCGGCTGGCACGGTCTGGGTAACACCCGTTTCAAATCCAGTA
CCAACCGTGCACCGCGTCAGACTACGCCGGGCAAGCCGGGCGAGCAGCGCGACCTGAAGCTGGAAATGAAGGTTCTGGCC
GATGTCGGTCTGCTGGGCCTGCCGAACGCCGGTAAAAGTACCTTTATCCGTTCGGTGTCGGCTGCCAAGCCGAAAGTCGC
CGATTACCCGTTCACCACTCTGGTGCCGAACCTCGGTGTGGTCAGTGTTGACCGCTGGAAGAGTTTCGTCATTGCCGACA
TTCCGGGTCTGATCGAAGGTGCTTCCGACGGTGCCGGCCTGGGGATCCGTTTCCTCAAGCACCTGGCGCGTACTCGTCTG
TTGCTGCACCTCGTGGACATGGCGCCGCTGGATGAAAGCAGTGCGCCGGACGCCGCTGAAGTGATCGTCAACGAGCTGAT
CAAGTTCAGTCCGTCGCTGGCCGAGCGTGATCGCTGGCTGGTGCTGAACAAGTGCGACCAGATCCTCGAAGAAGAGCACG
AAGCGCGGGTCAAGGAAATCGTTGATCGTCTGGAGTGGACCGGTCCGGTCTACGTGATTTCGGCCATTGCCAAAGAAGGC
ACCGAGCGCCTGACGCGCGACATCATGCGCTACCTGGAGGATCGTGCCGATCGCCTGGCCAATGATCCGGCCTACAAGGA
AGAGCTGGCCGATCTCGATCAGCGCATCGAAGACGAAGCCCGTGCGCAGTTGCAGGCGCTGGATGACAAGCGTGCCCTGC
GTCGCAGTGGCGTGAAGTCGGTTCACGACATCGGCGACGATGATTGGGACGAAGAAGATGTGGATGACGAAGACGGTCCG
GAAATCATTTACGTGCGTGACTGA

Upstream 100 bases:

>100_bases
TGCGATGCAGGTCGTGGATTGGGGTCGCTGCGCTCATTTTTGCAAGAGTCTTATGTCTTGATTGTTTTTCGGCTCGTCCG
TACGGCGAGAGGCGTTGGTT

Downstream 100 bases:

>100_bases
TTCGTTGCAGTAAACTTAAGCGCCGCTCAATCGAGCGGCGTTTTAGTATCTGGAAATCGATTGTTGGTCACGAAGAATCA
CGAATAACGTCACGGGCAGA

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MKFVDEVSIRVKAGDGGNGCMSFRREKFIENGGPNGGDGGDGGSIFMMADENLNTLVDYRYTRHFDAERGSNGGSTDCTG
KKGEDLILRVPVGTTVIDSATQEVIGDLTKAGQKLMVVQGGWHGLGNTRFKSSTNRAPRQTTPGKPGEQRDLKLEMKVLA
DVGLLGLPNAGKSTFIRSVSAAKPKVADYPFTTLVPNLGVVSVDRWKSFVIADIPGLIEGASDGAGLGIRFLKHLARTRL
LLHLVDMAPLDESSAPDAAEVIVNELIKFSPSLAERDRWLVLNKCDQILEEEHEARVKEIVDRLEWTGPVYVISAIAKEG
TERLTRDIMRYLEDRADRLANDPAYKEELADLDQRIEDEARAQLQALDDKRALRRSGVKSVHDIGDDDWDEEDVDDEDGP
EIIYVRD

Sequences:

>Translated_407_residues
MKFVDEVSIRVKAGDGGNGCMSFRREKFIENGGPNGGDGGDGGSIFMMADENLNTLVDYRYTRHFDAERGSNGGSTDCTG
KKGEDLILRVPVGTTVIDSATQEVIGDLTKAGQKLMVVQGGWHGLGNTRFKSSTNRAPRQTTPGKPGEQRDLKLEMKVLA
DVGLLGLPNAGKSTFIRSVSAAKPKVADYPFTTLVPNLGVVSVDRWKSFVIADIPGLIEGASDGAGLGIRFLKHLARTRL
LLHLVDMAPLDESSAPDAAEVIVNELIKFSPSLAERDRWLVLNKCDQILEEEHEARVKEIVDRLEWTGPVYVISAIAKEG
TERLTRDIMRYLEDRADRLANDPAYKEELADLDQRIEDEARAQLQALDDKRALRRSGVKSVHDIGDDDWDEEDVDDEDGP
EIIYVRD
>Mature_407_residues
MKFVDEVSIRVKAGDGGNGCMSFRREKFIENGGPNGGDGGDGGSIFMMADENLNTLVDYRYTRHFDAERGSNGGSTDCTG
KKGEDLILRVPVGTTVIDSATQEVIGDLTKAGQKLMVVQGGWHGLGNTRFKSSTNRAPRQTTPGKPGEQRDLKLEMKVLA
DVGLLGLPNAGKSTFIRSVSAAKPKVADYPFTTLVPNLGVVSVDRWKSFVIADIPGLIEGASDGAGLGIRFLKHLARTRL
LLHLVDMAPLDESSAPDAAEVIVNELIKFSPSLAERDRWLVLNKCDQILEEEHEARVKEIVDRLEWTGPVYVISAIAKEG
TERLTRDIMRYLEDRADRLANDPAYKEELADLDQRIEDEARAQLQALDDKRALRRSGVKSVHDIGDDDWDEEDVDDEDGP
EIIYVRD

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=322, Percent_Identity=39.4409937888199, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI111955139, Length=316, Percent_Identity=36.0759493670886, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI111955063, Length=208, Percent_Identity=35.5769230769231, Blast_Score=108, Evalue=7e-24,
Organism=Escherichia coli, GI1789574, Length=371, Percent_Identity=59.0296495956873, Blast_Score=404, Evalue=1e-114,
Organism=Escherichia coli, GI1787454, Length=100, Percent_Identity=37, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508313, Length=341, Percent_Identity=33.7243401759531, Blast_Score=148, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI17552324, Length=308, Percent_Identity=29.2207792207792, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17509631, Length=100, Percent_Identity=39, Blast_Score=72, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6321962, Length=130, Percent_Identity=42.3076923076923, Blast_Score=113, Evalue=6e-26,
Organism=Drosophila melanogaster, GI20129375, Length=343, Percent_Identity=39.067055393586, Blast_Score=172, Evalue=4e-43,
Organism=Drosophila melanogaster, GI24585318, Length=310, Percent_Identity=34.8387096774194, Blast_Score=160, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 44807; Mature: 44807

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFVDEVSIRVKAGDGGNGCMSFRREKFIENGGPNGGDGGDGGSIFMMADENLNTLVDYR
CCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCHHHHHH
YTRHFDAERGSNGGSTDCTGKKGEDLILRVPVGTTVIDSATQEVIGDLTKAGQKLMVVQG
HHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEEC
GWHGLGNTRFKSSTNRAPRQTTPGKPGEQRDLKLEMKVLADVGLLGLPNAGKSTFIRSVS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
AAKPKVADYPFTTLVPNLGVVSVDRWKSFVIADIPGLIEGASDGAGLGIRFLKHLARTRL
HCCCCCCCCCHHHHCCCCCEEEHHHHHHEEEECCCHHHCCCCCCCCHHHHHHHHHHHHHH
LLHLVDMAPLDESSAPDAAEVIVNELIKFSPSLAERDRWLVLNKCDQILEEEHEARVKEI
HHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHHCCCCEEEHHHHHHHHHHHHHHHHHHH
VDRLEWTGPVYVISAIAKEGTERLTRDIMRYLEDRADRLANDPAYKEELADLDQRIEDEA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
RAQLQALDDKRALRRSGVKSVHDIGDDDWDEEDVDDEDGPEIIYVRD
HHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCEEEEEEC
>Mature Secondary Structure
MKFVDEVSIRVKAGDGGNGCMSFRREKFIENGGPNGGDGGDGGSIFMMADENLNTLVDYR
CCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCHHHHHH
YTRHFDAERGSNGGSTDCTGKKGEDLILRVPVGTTVIDSATQEVIGDLTKAGQKLMVVQG
HHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEEC
GWHGLGNTRFKSSTNRAPRQTTPGKPGEQRDLKLEMKVLADVGLLGLPNAGKSTFIRSVS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
AAKPKVADYPFTTLVPNLGVVSVDRWKSFVIADIPGLIEGASDGAGLGIRFLKHLARTRL
HCCCCCCCCCHHHHCCCCCEEEHHHHHHEEEECCCHHHCCCCCCCCHHHHHHHHHHHHHH
LLHLVDMAPLDESSAPDAAEVIVNELIKFSPSLAERDRWLVLNKCDQILEEEHEARVKEI
HHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHHCCCCEEEHHHHHHHHHHHHHHHHHHH
VDRLEWTGPVYVISAIAKEGTERLTRDIMRYLEDRADRLANDPAYKEELADLDQRIEDEA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
RAQLQALDDKRALRRSGVKSVHDIGDDDWDEEDVDDEDGPEIIYVRD
HHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA