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The map label for this gene is ispH [H]

Identifier: 77461070

GI number: 77461070

Start: 5468129

End: 5469073

Strand: Reverse

Name: ispH [H]

Synonym: Pfl01_4849

Alternate gene names: 77461070

Gene position: 5469073-5468129 (Counterclockwise)

Preceding gene: 77461071

Following gene: 77461068

Centisome position: 84.94

GC content: 62.01

Gene sequence:

>945_bases
ATGCAAATCAAACTCGCCAACCCCCGTGGCTTCTGCGCCGGCGTGGACCGGGCGATCGAAATCGTCAACCGCGCCCTGGA
GGTCTTCGGGCCGCCGATCTATGTGCGTCACGAAGTGGTGCACAACAAGTTTGTGGTCGAAGACCTGCGCATTCGTGGCG
CGATTTTCGTCGAGGAACTCGATCAGGTACCGGACGACGTTATCGTGATCTTCAGTGCCCACGGCGTCTCGCAAGCCGTG
CGCACCGAAGCCGCCGGCCGTGGCCTGAAAGTGTTCGACGCTACCTGTCCATTGGTGACCAAGGTACACATCGAAGTCGC
GAAATACAGCCGCGACGGCCGTGAATGCATCCTGATCGGTCACGCCGGTCACCCGGAAGTCGAAGGCACCATGGGCCAGT
ACGACGCCAGCAATGGCGGTGCGATCTACCTCGTCGAAGACGAGAAGGATGTCGCCGAGTTGCAGGTACATAACCCGGAC
AAACTGGCCTTCGTCACCCAGACCACACTGTCCATGGATGACACCAGCCGTGTCATCGATGCGCTGCGTACGCGTTTCCC
GGCCATTGGCGGGCCGCGCAAGGACGATATCTGCTACGCCACACAAAACCGTCAGGACGCGGTCAAGCAACTGGCCGACG
AATGCGACGTGGTGTTGGTGGTGGGCAGCCCTAACAGCTCCAACTCCAACCGCCTGCGTGAACTGGCCGAACGCATGGCC
ACGCCGGCCTACCTGATCGACGGCGCCGAAGACCTGCAAAAGAGCTGGTTCGACGGTGTCGAGCGTATCGGCATCACCGC
CGGCGCCTCCGCCCCGGAAGTTCTGGTGCGTGGCGTGATCCAGCAGTTGCAGGCCTGGGGCGCCACCGGCGCCGACGAAC
TGGCCGGGCGTGAGGAGAACATCACGTTCTCGATGCCTAAAGAGCTGCGCGTTCGCTCGATCTGA

Upstream 100 bases:

>100_bases
AATCTTCTCCGTCAAAGCGCTGTAATTGCTGTTCTGCAGGAGCCGGCTGACCGGCTCCTGTAATGATCCAATCTTTCGCG
CGCAAGACACGAGGCACCGC

Downstream 100 bases:

>100_bases
TCGCTTTATCCTTTCGACACAGCGCCTGTTCAGCCTTTTGACTGACCAGGCGTACGCGACCGGTTGCCGCCAGCACCACC
TGGAGCTGGCTTACCGGCTC

Product: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MQIKLANPRGFCAGVDRAIEIVNRALEVFGPPIYVRHEVVHNKFVVEDLRIRGAIFVEELDQVPDDVIVIFSAHGVSQAV
RTEAAGRGLKVFDATCPLVTKVHIEVAKYSRDGRECILIGHAGHPEVEGTMGQYDASNGGAIYLVEDEKDVAELQVHNPD
KLAFVTQTTLSMDDTSRVIDALRTRFPAIGGPRKDDICYATQNRQDAVKQLADECDVVLVVGSPNSSNSNRLRELAERMA
TPAYLIDGAEDLQKSWFDGVERIGITAGASAPEVLVRGVIQQLQAWGATGADELAGREENITFSMPKELRVRSI

Sequences:

>Translated_314_residues
MQIKLANPRGFCAGVDRAIEIVNRALEVFGPPIYVRHEVVHNKFVVEDLRIRGAIFVEELDQVPDDVIVIFSAHGVSQAV
RTEAAGRGLKVFDATCPLVTKVHIEVAKYSRDGRECILIGHAGHPEVEGTMGQYDASNGGAIYLVEDEKDVAELQVHNPD
KLAFVTQTTLSMDDTSRVIDALRTRFPAIGGPRKDDICYATQNRQDAVKQLADECDVVLVVGSPNSSNSNRLRELAERMA
TPAYLIDGAEDLQKSWFDGVERIGITAGASAPEVLVRGVIQQLQAWGATGADELAGREENITFSMPKELRVRSI
>Mature_314_residues
MQIKLANPRGFCAGVDRAIEIVNRALEVFGPPIYVRHEVVHNKFVVEDLRIRGAIFVEELDQVPDDVIVIFSAHGVSQAV
RTEAAGRGLKVFDATCPLVTKVHIEVAKYSRDGRECILIGHAGHPEVEGTMGQYDASNGGAIYLVEDEKDVAELQVHNPD
KLAFVTQTTLSMDDTSRVIDALRTRFPAIGGPRKDDICYATQNRQDAVKQLADECDVVLVVGSPNSSNSNRLRELAERMA
TPAYLIDGAEDLQKSWFDGVERIGITAGASAPEVLVRGVIQQLQAWGATGADELAGREENITFSMPKELRVRSI

Specific function: Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) [H]

COG id: COG0761

COG function: function code IM; Penicillin tolerance protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispH family [H]

Homologues:

Organism=Escherichia coli, GI1786212, Length=311, Percent_Identity=68.1672025723473, Blast_Score=428, Evalue=1e-121,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003451 [H]

Pfam domain/function: PF02401 LYTB [H]

EC number: =1.17.1.2 [H]

Molecular weight: Translated: 34362; Mature: 34362

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIKLANPRGFCAGVDRAIEIVNRALEVFGPPIYVRHEVVHNKFVVEDLRIRGAIFVEEL
CEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
DQVPDDVIVIFSAHGVSQAVRTEAAGRGLKVFDATCPLVTKVHIEVAKYSRDGRECILIG
HCCCCCEEEEEECCCHHHHHHHHHCCCCCEEEECCCCEEEEEEEEEEECCCCCCEEEEEE
HAGHPEVEGTMGQYDASNGGAIYLVEDEKDVAELQVHNPDKLAFVTQTTLSMDDTSRVID
CCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCEEEEEEEEECCCHHHHHHH
ALRTRFPAIGGPRKDDICYATQNRQDAVKQLADECDVVLVVGSPNSSNSNRLRELAERMA
HHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHC
TPAYLIDGAEDLQKSWFDGVERIGITAGASAPEVLVRGVIQQLQAWGATGADELAGREEN
CCEEEECCHHHHHHHHHHHHHHCCEECCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCC
ITFSMPKELRVRSI
EEEECCHHHHCCCC
>Mature Secondary Structure
MQIKLANPRGFCAGVDRAIEIVNRALEVFGPPIYVRHEVVHNKFVVEDLRIRGAIFVEEL
CEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
DQVPDDVIVIFSAHGVSQAVRTEAAGRGLKVFDATCPLVTKVHIEVAKYSRDGRECILIG
HCCCCCEEEEEECCCHHHHHHHHHCCCCCEEEECCCCEEEEEEEEEEECCCCCCEEEEEE
HAGHPEVEGTMGQYDASNGGAIYLVEDEKDVAELQVHNPDKLAFVTQTTLSMDDTSRVID
CCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCEEEEEEEEECCCHHHHHHH
ALRTRFPAIGGPRKDDICYATQNRQDAVKQLADECDVVLVVGSPNSSNSNRLRELAERMA
HHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHC
TPAYLIDGAEDLQKSWFDGVERIGITAGASAPEVLVRGVIQQLQAWGATGADELAGREEN
CCEEEECCHHHHHHHHHHHHHHCCEECCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCC
ITFSMPKELRVRSI
EEEECCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA