Click here to switch to the map view.

The map label for this gene is can [H]

Identifier: 77460994

GI number: 77460994

Start: 5381859

End: 5382503

Strand: Reverse

Name: can [H]

Synonym: Pfl01_4773

Alternate gene names: 77460994

Gene position: 5382503-5381859 (Counterclockwise)

Preceding gene: 77460996

Following gene: 77460988

Centisome position: 83.6

GC content: 59.38

Gene sequence:

>645_bases
ATGCATGACTTACAAGACCTGATTGATAACAACGAGCGTTGGGCTGACGCGATCACCAAGGAAGACCCGGATTTCTTCGC
CAAGCTGGCCCGTCAGCAGACGCCTGAATATCTGTGGATCGGCTGCTCCGACGCACGGGTTCCGGCCAATGAAATCGTCG
GCATGCTGCCGGGCGATCTGTTCGTTCACCGCAACGTCGCCAACGTGGTGCTGCACACCGACCTCAACTGCCTGTCGGTG
ATCCAGTACGCAGTGGACGTGCTCAAGGTCAAACATATCCTGGTGACCGGACACTACGGCTGCGGCGGTGTGCGGGCGTC
GATGCAGGATCGTCAGTTCGGCCTGATCGATGGCTGGCTGCGTTCGATCCGTGACCTGTACTACGAGAAACGCGAAGAAC
TGGCCAGGCTGCCGACCGAAGAAGAACAGGTCGATCGTCTGTGCGAGCTCAACGTGATTCAGCAAGTGGCCAACGTCGCC
CACACCAGCATCATCCAGAACGCCTGGCATCGCGGGCAGAGCCTGTCGATCCACGGTTGCATCTACGGCATCAAGGATGG
TCGCTGGAAGAGCCTGAACACCACGATCAGCGGTTTCGAGCAATTACCGCCGCAGTACCGCTTGCGTCCGGTCGGCGCGC
CTTGA

Upstream 100 bases:

>100_bases
CGGGCGCGCGAGAATTCAAAGCAAATCACCAGCGATCCGTGCGTGACCCCGACGGGCGGTCGACTGTCATACCAGCGCAT
CTTTCTTGAGGCCTTACAGC

Downstream 100 bases:

>100_bases
CCGGTCGTTCAGCGTAAACCTTGTCGCCGCCAGCTGAGCAAATAGCGCTGGCCTTCAAGATTGGGTGATTCGTCGTAACC
GGTGATCCACCCGCGGCAGC

Product: carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MHDLQDLIDNNERWADAITKEDPDFFAKLARQQTPEYLWIGCSDARVPANEIVGMLPGDLFVHRNVANVVLHTDLNCLSV
IQYAVDVLKVKHILVTGHYGCGGVRASMQDRQFGLIDGWLRSIRDLYYEKREELARLPTEEEQVDRLCELNVIQQVANVA
HTSIIQNAWHRGQSLSIHGCIYGIKDGRWKSLNTTISGFEQLPPQYRLRPVGAP

Sequences:

>Translated_214_residues
MHDLQDLIDNNERWADAITKEDPDFFAKLARQQTPEYLWIGCSDARVPANEIVGMLPGDLFVHRNVANVVLHTDLNCLSV
IQYAVDVLKVKHILVTGHYGCGGVRASMQDRQFGLIDGWLRSIRDLYYEKREELARLPTEEEQVDRLCELNVIQQVANVA
HTSIIQNAWHRGQSLSIHGCIYGIKDGRWKSLNTTISGFEQLPPQYRLRPVGAP
>Mature_214_residues
MHDLQDLIDNNERWADAITKEDPDFFAKLARQQTPEYLWIGCSDARVPANEIVGMLPGDLFVHRNVANVVLHTDLNCLSV
IQYAVDVLKVKHILVTGHYGCGGVRASMQDRQFGLIDGWLRSIRDLYYEKREELARLPTEEEQVDRLCELNVIQQVANVA
HTSIIQNAWHRGQSLSIHGCIYGIKDGRWKSLNTTISGFEQLPPQYRLRPVGAP

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=207, Percent_Identity=54.1062801932367, Blast_Score=251, Evalue=3e-68,
Organism=Escherichia coli, GI1786534, Length=214, Percent_Identity=28.9719626168224, Blast_Score=80, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6324292, Length=211, Percent_Identity=29.8578199052133, Blast_Score=117, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 24346; Mature: 24346

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHDLQDLIDNNERWADAITKEDPDFFAKLARQQTPEYLWIGCSDARVPANEIVGMLPGDL
CCCHHHHHCCCHHHHHHHCCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCHH
FVHRNVANVVLHTDLNCLSVIQYAVDVLKVKHILVTGHYGCGGVRASMQDRQFGLIDGWL
EEECCHHHHHEECCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCHHHHHH
RSIRDLYYEKREELARLPTEEEQVDRLCELNVIQQVANVAHTSIIQNAWHRGQSLSIHGC
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
IYGIKDGRWKSLNTTISGFEQLPPQYRLRPVGAP
EEECCCCCCCCHHHHHHHHHHCCCCCCCEECCCC
>Mature Secondary Structure
MHDLQDLIDNNERWADAITKEDPDFFAKLARQQTPEYLWIGCSDARVPANEIVGMLPGDL
CCCHHHHHCCCHHHHHHHCCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCHH
FVHRNVANVVLHTDLNCLSVIQYAVDVLKVKHILVTGHYGCGGVRASMQDRQFGLIDGWL
EEECCHHHHHEECCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCHHHHHH
RSIRDLYYEKREELARLPTEEEQVDRLCELNVIQQVANVAHTSIIQNAWHRGQSLSIHGC
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
IYGIKDGRWKSLNTTISGFEQLPPQYRLRPVGAP
EEECCCCCCCCHHHHHHHHHHCCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]