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The map label for this gene is mlrA [H]

Identifier: 77460956

GI number: 77460956

Start: 5340339

End: 5341280

Strand: Direct

Name: mlrA [H]

Synonym: Pfl01_4735

Alternate gene names: 77460956

Gene position: 5340339-5341280 (Clockwise)

Preceding gene: 77460955

Following gene: 77460957

Centisome position: 82.95

GC content: 61.36

Gene sequence:

>942_bases
ATGAACGACTCACCCGACACCAGCGCCCGGGAAGACCTCGGCGCCGACTTCAAGAAAGCCCTCGACGAAGGCTGGCTGCC
GATCCGCGAAGTCGCGCGTCAGACCGGCGTCAATGCCGTCACCCTGCGCGCTTGGGAACGGCGCTACGGGCTGATCGTGC
CGCAACGCACGCCCAAGGGCCATCGCCTGTACAACGCCGATCATGTGCTGCGTATCCAGAATATTCTCACCTGGCTCAAC
CGTGGCGTAGCGGTCAGCCAGGTCAAACCGCTGCTCGACACGGCGCAGGCCTTGAACGAACCGGTGGAAGACGAATGGCA
TCCCCTGCGTCAGGCCGCCCTGTTGGCGGTCACTCAACTGAACGAGCGCAGCCTTGATGACAGCGTCAACCAGGCGATGG
CGCTGTATCCGCCACGCACCCTGTGCGAGCAATTGTTGCTGCCGCTGCTGAGCGATCTCGAACAACGTTGGCAGGGCCAG
TTCGGCGCGCAGATGGAGCGCGTGTTCTTTTATGCCTGGTTGCGCAGCAAATTCGGCGCACGCATCTACCATAACAACCG
TCAGTTGCGCACTGCGCCGCTGCTGCTGGTCAATCAATCGGATCTGGCGCTGGAGCCGCATCTGTGGCTCTGCGCCTGGC
TCATCAGCAGCGCCGATTGCCCGGTACAAGTACTCGACTGGCCGCTGCCGGCCGGCGAACTGGCATTGGCAACCGATACC
CTGCAAGCCCGTGGCGTACTGCTGTATTCCAGCAAAGCCCTGAACCTTGCCCAACTGCCGAAACTGTTGAATGGCATCAG
TTGCCCGAAACTGATTGCCGGACCCACGGTGTGCATTCACCACGCCGAGTTGTCCGCCAGAACTTCCGAAATCGCAGATC
TGCTGCTGGCCGAAGATCCTCTTTCGGCGCATCGGGCACTCGTTCAGCGTGGGTTGATTTAA

Upstream 100 bases:

>100_bases
TGCTCAAGCATCACTTTCGCCTCCACCCGGATCCCTACATTGCGCAGCAGGTGTACCTGCAGCCGCATCCGGAAAACCTC
AGTCTGCGAAACGCCATTTG

Downstream 100 bases:

>100_bases
TGATTCAGACAGAAACCGACATGCAATTGATCTGGCTGCGCAGCGACTTGCGCCAACATGACAACACTGCCCTCGCAGCC
GCCGCCGAGCGTGGCCCGAG

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: MerR-like regulator A [H]

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MNDSPDTSAREDLGADFKKALDEGWLPIREVARQTGVNAVTLRAWERRYGLIVPQRTPKGHRLYNADHVLRIQNILTWLN
RGVAVSQVKPLLDTAQALNEPVEDEWHPLRQAALLAVTQLNERSLDDSVNQAMALYPPRTLCEQLLLPLLSDLEQRWQGQ
FGAQMERVFFYAWLRSKFGARIYHNNRQLRTAPLLLVNQSDLALEPHLWLCAWLISSADCPVQVLDWPLPAGELALATDT
LQARGVLLYSSKALNLAQLPKLLNGISCPKLIAGPTVCIHHAELSARTSEIADLLLAEDPLSAHRALVQRGLI

Sequences:

>Translated_313_residues
MNDSPDTSAREDLGADFKKALDEGWLPIREVARQTGVNAVTLRAWERRYGLIVPQRTPKGHRLYNADHVLRIQNILTWLN
RGVAVSQVKPLLDTAQALNEPVEDEWHPLRQAALLAVTQLNERSLDDSVNQAMALYPPRTLCEQLLLPLLSDLEQRWQGQ
FGAQMERVFFYAWLRSKFGARIYHNNRQLRTAPLLLVNQSDLALEPHLWLCAWLISSADCPVQVLDWPLPAGELALATDT
LQARGVLLYSSKALNLAQLPKLLNGISCPKLIAGPTVCIHHAELSARTSEIADLLLAEDPLSAHRALVQRGLI
>Mature_313_residues
MNDSPDTSAREDLGADFKKALDEGWLPIREVARQTGVNAVTLRAWERRYGLIVPQRTPKGHRLYNADHVLRIQNILTWLN
RGVAVSQVKPLLDTAQALNEPVEDEWHPLRQAALLAVTQLNERSLDDSVNQAMALYPPRTLCEQLLLPLLSDLEQRWQGQ
FGAQMERVFFYAWLRSKFGARIYHNNRQLRTAPLLLVNQSDLALEPHLWLCAWLISSADCPVQVLDWPLPAGELALATDT
LQARGVLLYSSKALNLAQLPKLLNGISCPKLIAGPTVCIHHAELSARTSEIADLLLAEDPLSAHRALVQRGLI

Specific function: Transcriptional activator of the csg genes required for production of the curli (AgF) [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788448, Length=127, Percent_Identity=40.9448818897638, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787409, Length=208, Percent_Identity=30.2884615384615, Blast_Score=89, Evalue=5e-19,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551 [H]

Pfam domain/function: PF00376 MerR [H]

EC number: NA

Molecular weight: Translated: 35066; Mature: 35066

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDSPDTSAREDLGADFKKALDEGWLPIREVARQTGVNAVTLRAWERRYGLIVPQRTPKG
CCCCCCCCHHHHHCHHHHHHHHCCCCHHHHHHHHCCCCEEEHHHHHHHCCEEECCCCCCC
HRLYNADHVLRIQNILTWLNRGVAVSQVKPLLDTAQALNEPVEDEWHPLRQAALLAVTQL
CEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
NERSLDDSVNQAMALYPPRTLCEQLLLPLLSDLEQRWQGQFGAQMERVFFYAWLRSKFGA
HHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
RIYHNNRQLRTAPLLLVNQSDLALEPHLWLCAWLISSADCPVQVLDWPLPAGELALATDT
EEEECCCEEEECCEEEECCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEHHH
LQARGVLLYSSKALNLAQLPKLLNGISCPKLIAGPTVCIHHAELSARTSEIADLLLAEDP
HHHCEEEEECCCCCCHHHHHHHHCCCCCCHHHCCCEEEEECCHHHHHHHHHHHHHHCCCC
LSAHRALVQRGLI
HHHHHHHHHHCCC
>Mature Secondary Structure
MNDSPDTSAREDLGADFKKALDEGWLPIREVARQTGVNAVTLRAWERRYGLIVPQRTPKG
CCCCCCCCHHHHHCHHHHHHHHCCCCHHHHHHHHCCCCEEEHHHHHHHCCEEECCCCCCC
HRLYNADHVLRIQNILTWLNRGVAVSQVKPLLDTAQALNEPVEDEWHPLRQAALLAVTQL
CEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
NERSLDDSVNQAMALYPPRTLCEQLLLPLLSDLEQRWQGQFGAQMERVFFYAWLRSKFGA
HHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
RIYHNNRQLRTAPLLLVNQSDLALEPHLWLCAWLISSADCPVQVLDWPLPAGELALATDT
EEEECCCEEEECCEEEECCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEHHH
LQARGVLLYSSKALNLAQLPKLLNGISCPKLIAGPTVCIHHAELSARTSEIADLLLAEDP
HHHCEEEEECCCCCCHHHHHHHHCCCCCCHHHCCCEEEEECCHHHHHHHHHHHHHHCCCC
LSAHRALVQRGLI
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11489123; 9278503 [H]