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The map label for this gene is ftsW [H]

Identifier: 77460895

GI number: 77460895

Start: 5276218

End: 5277435

Strand: Reverse

Name: ftsW [H]

Synonym: Pfl01_4674

Alternate gene names: 77460895

Gene position: 5277435-5276218 (Counterclockwise)

Preceding gene: 77460896

Following gene: 77460894

Centisome position: 81.97

GC content: 61.99

Gene sequence:

>1218_bases
ATGAGCTTGAGAAACATCATCAAGCCATACCCGTCGCCGCTCATTACCGGACGCGGAATCGACCTCGACTTCCCGATGCT
CGCCGGTTGCCTGGCGTTGCTCGGTCTGGGCCTGATCATGATCGCCTCGGCATCGACAGAAGTCGGCGCAGCGCAGTCGG
GCAGTGCTCTGTATTACATGACCCGTCACCTGATCTACGTGGTGCTGGGCCTGGGCGCGTGCGTCGTCACCATGATGATT
CCGATCGCCACCTGGCAGCGGCTGGGCTGGCTGATGCTGATCGGCGCGTTCGGCCTGCTGGTGATGGTGATCATCCCCGG
GATCGGCCGTGAGGTGAACGGTTCGATGCGCTGGATCGGTTTCAGCTTCTTCAACGTGCAGCCGTCCGAGATCGCCAAGG
TGTTCGTGGTGATCTACCTCGCCGGTTATCTGGTGCGTCGCCAGAAAGAAGTGCGCGAGAGCTGGATGGGCTTCTTCAAG
CCGTTCATCGTGCTGCTGCCGATGGCGGGCCTGCTCCTGATGGAGCCGGACTTCGGTGCCACCGTCGTGATGATGGGCGC
TGCGGCGGCGATGCTGTTCCTCGGCGGGGTCGGGCTGTTCCGGTTCTCGCTGATGGTGGTGCTGGCCGTCGGTGCGGTGG
TGTTGCTGATTCAGATGCAGCCGTACCGGATGGCGCGTCTTACCAACTTCGCCGACCCGTGGGCCGACCAGTTCGGCGCC
GGTTATCAGTTGTCGCAAGCCCTGATCGCGTTCGGTCGCGGTGAATGGCTGGGCGTCGGCCTGGGAAACAGCGTGCAGAA
GCAGTTCTACCTGCCGGAAGCGCACACCGACTTCGTGTTCTCGGTGCTGGCCGAAGAGCTCGGCGCGGTCGGCTCGCTGT
GCACCGTGGCGCTGTTCGTGTTCGTGTGTATTCGCGGCATGTACATCGGTCTGTGGGCCGAGAAAGCCAAACAGTTTTTT
GCCGCTTATGTTGCCTACGGCCTGTCGTTCCTGTGGATCGGCCAGTTCCTGATCAACATCGGTGTGAACGTCGGCCTGTT
GCCGACCAAGGGCCTGACCTTGCCGTTCCTCAGTTATGGCGGCAGTTCCCTGGTGATCTGCTGCGCCTGCCTTGGCCTGT
TGCTGAGGATCGAGTGGGAGAGCCGGACCCACCTGGGCAGTGAAGAGATGGAATTCCATGAGAGCGACTTCGCCGAGGAG
CCGAACCATGGGCGCTAA

Upstream 100 bases:

>100_bases
GAGACGTGGTGCTGCTGTCGCCGGCCTGCGCCAGTTTCGACATGTTCAATAACTACGAAGACCGTGGTCACCAGTTCGTC
CGCGCCGTGGAGGATCTGGC

Downstream 100 bases:

>100_bases
CGTATTGATCATGGCCGGCGGCACCGGTGGCCACGTGTTCCCGGCGCTGGCCTGTGCCCGCGAATTCCAGGCACGCGGCT
ACACCGTGCACTGGCTCGGT

Product: cell cycle protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MSLRNIIKPYPSPLITGRGIDLDFPMLAGCLALLGLGLIMIASASTEVGAAQSGSALYYMTRHLIYVVLGLGACVVTMMI
PIATWQRLGWLMLIGAFGLLVMVIIPGIGREVNGSMRWIGFSFFNVQPSEIAKVFVVIYLAGYLVRRQKEVRESWMGFFK
PFIVLLPMAGLLLMEPDFGATVVMMGAAAAMLFLGGVGLFRFSLMVVLAVGAVVLLIQMQPYRMARLTNFADPWADQFGA
GYQLSQALIAFGRGEWLGVGLGNSVQKQFYLPEAHTDFVFSVLAEELGAVGSLCTVALFVFVCIRGMYIGLWAEKAKQFF
AAYVAYGLSFLWIGQFLINIGVNVGLLPTKGLTLPFLSYGGSSLVICCACLGLLLRIEWESRTHLGSEEMEFHESDFAEE
PNHGR

Sequences:

>Translated_405_residues
MSLRNIIKPYPSPLITGRGIDLDFPMLAGCLALLGLGLIMIASASTEVGAAQSGSALYYMTRHLIYVVLGLGACVVTMMI
PIATWQRLGWLMLIGAFGLLVMVIIPGIGREVNGSMRWIGFSFFNVQPSEIAKVFVVIYLAGYLVRRQKEVRESWMGFFK
PFIVLLPMAGLLLMEPDFGATVVMMGAAAAMLFLGGVGLFRFSLMVVLAVGAVVLLIQMQPYRMARLTNFADPWADQFGA
GYQLSQALIAFGRGEWLGVGLGNSVQKQFYLPEAHTDFVFSVLAEELGAVGSLCTVALFVFVCIRGMYIGLWAEKAKQFF
AAYVAYGLSFLWIGQFLINIGVNVGLLPTKGLTLPFLSYGGSSLVICCACLGLLLRIEWESRTHLGSEEMEFHESDFAEE
PNHGR
>Mature_404_residues
SLRNIIKPYPSPLITGRGIDLDFPMLAGCLALLGLGLIMIASASTEVGAAQSGSALYYMTRHLIYVVLGLGACVVTMMIP
IATWQRLGWLMLIGAFGLLVMVIIPGIGREVNGSMRWIGFSFFNVQPSEIAKVFVVIYLAGYLVRRQKEVRESWMGFFKP
FIVLLPMAGLLLMEPDFGATVVMMGAAAAMLFLGGVGLFRFSLMVVLAVGAVVLLIQMQPYRMARLTNFADPWADQFGAG
YQLSQALIAFGRGEWLGVGLGNSVQKQFYLPEAHTDFVFSVLAEELGAVGSLCTVALFVFVCIRGMYIGLWAEKAKQFFA
AYVAYGLSFLWIGQFLINIGVNVGLLPTKGLTLPFLSYGGSSLVICCACLGLLLRIEWESRTHLGSEEMEFHESDFAEEP
NHGR

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=360, Percent_Identity=43.6111111111111, Blast_Score=293, Evalue=2e-80,
Organism=Escherichia coli, GI1786853, Length=336, Percent_Identity=32.4404761904762, Blast_Score=139, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 44285; Mature: 44154

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SLRNIIKPYPSPLITGRGIDLDFPMLAGCLALLGLGLIMIASASTEVGAAQSGSALYYM
CCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
TRHLIYVVLGLGACVVTMMIPIATWQRLGWLMLIGAFGLLVMVIIPGIGREVNGSMRWIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEE
FSFFNVQPSEIAKVFVVIYLAGYLVRRQKEVRESWMGFFKPFIVLLPMAGLLLMEPDFGA
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCH
TVVMMGAAAAMLFLGGVGLFRFSLMVVLAVGAVVLLIQMQPYRMARLTNFADPWADQFGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHCC
GYQLSQALIAFGRGEWLGVGLGNSVQKQFYLPEAHTDFVFSVLAEELGAVGSLCTVALFV
CHHHHHHHHHHCCCCEEEECCCCHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FVCIRGMYIGLWAEKAKQFFAAYVAYGLSFLWIGQFLINIGVNVGLLPTKGLTLPFLSYG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHCC
GSSLVICCACLGLLLRIEWESRTHLGSEEMEFHESDFAEEPNHGR
CHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]