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The map label for this gene is ybdL [H]

Identifier: 77460817

GI number: 77460817

Start: 5196591

End: 5197739

Strand: Reverse

Name: ybdL [H]

Synonym: Pfl01_4596

Alternate gene names: 77460817

Gene position: 5197739-5196591 (Counterclockwise)

Preceding gene: 77460818

Following gene: 77460816

Centisome position: 80.73

GC content: 60.66

Gene sequence:

>1149_bases
ATGATCACCAGCAAGCTGCCGAATGTCGGCATCACTATTTTCACGCAGATGTCTCAGCTCGCGGCGCAGACCGGAGCGAT
CAACCTTTCCCAGGGTTTTCCCGATTTCGACGGCCCGCAGGCACTGCGCGATGCAGTCGGTCGACACATCGCCAGCGGCC
ATAACCAGTATTCGCCCATGACCGGCCTGCCGGCGCTGCGCCAGCAGATCGCTGCGAAAATCGCCCGCAGTTATGGCGCC
AACGTCGATGCCGACACTGAAGTGACCGTGACCCCGGGCGCAACCCAGGCGATCTTCTGCGCTATCCAAGCGGTTATCCG
CACTGGCGACGAAGTCATCGTGTTCGACCCGGCCTACGACAGCTACGAGCCGGCGGTGGAACTGGCCGGCGGGCGCTGCG
TGCATGTGCAGCTGGGCCTGAAAGATTTCTCCATCGACTTCGACAGACTCAGCGCAGCCCTGAGCCCGCGCACGCGGATG
ATCATCCTCAACACCCCGCATAACCCGAGCGGTGCTTTGATCAGTCGCGCCGAACTGGATCAGTTGGCGGCGTTGATCCG
TGATCGCGACATCTATGTGATCAGCGACGAAGTCTACGAACACCTGGTGTTCGACGGTGTGCCGCACGTCAGCGTGCTGG
CCCATGAAGAGTTGTATCAGCGCGCATTCGTGGTCAGCTCGTTCGGCAAGACCTATCACGTCACAGGCTGGAAAACCGGT
TACGTCGTGGCGCCGCCGGCCCTGACGGCGGAGCTGCGCAAGGTGCACCAGTACGTCAGTTTCTGCGGTGTGACACCGTT
GCAGTATGCCCTGGCCGATTACATGGCCGAGCATCCGGAACACGTTGAAGAGCTGCCAGGCTTCTATCAGGCCAAGCGCG
ATCTGTTCTGTGATTTGCTCGCGCCGTCGCGATTCAGCTTCACCCGGGTCACCGGCACTTATTTCCAACTGGTCGATTAC
TCGCAGATTCGCCCTGACCTGAACGATGTCGAGATGGCGATGTGGATGACCCGCGAGCACGGCGTGGCAAGTATTCCGGT
GTCGGTGTTCTACCAGCATCCACCCGAAGGCCAGCGCTTGGTGCGCCTGTGCTTTGCCAAACGTGAGGAGACGCTGCGGG
AAGCGGCGGCCAAACTATGCGTGATTTGA

Upstream 100 bases:

>100_bases
AAGGGGCGCCGTTTGGCGCCCTTTTTTTATGGGCGCCGGATGGGCTATCCTCGGGCTCTCCCGCGCCGTCGTCAGAGCCG
GGGCAGAGCAGGGAACCCCG

Downstream 100 bases:

>100_bases
GTGCGTTGCCCGATCTCAATCTGGCGCTGATCCAGACCAGCCTGGCCTGGCATGACCGTCAGGCCAACCTCGAGCATTTC
GACGCCTTGCTGGAGCAGGC

Product: putative aminotransferase

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MITSKLPNVGITIFTQMSQLAAQTGAINLSQGFPDFDGPQALRDAVGRHIASGHNQYSPMTGLPALRQQIAAKIARSYGA
NVDADTEVTVTPGATQAIFCAIQAVIRTGDEVIVFDPAYDSYEPAVELAGGRCVHVQLGLKDFSIDFDRLSAALSPRTRM
IILNTPHNPSGALISRAELDQLAALIRDRDIYVISDEVYEHLVFDGVPHVSVLAHEELYQRAFVVSSFGKTYHVTGWKTG
YVVAPPALTAELRKVHQYVSFCGVTPLQYALADYMAEHPEHVEELPGFYQAKRDLFCDLLAPSRFSFTRVTGTYFQLVDY
SQIRPDLNDVEMAMWMTREHGVASIPVSVFYQHPPEGQRLVRLCFAKREETLREAAAKLCVI

Sequences:

>Translated_382_residues
MITSKLPNVGITIFTQMSQLAAQTGAINLSQGFPDFDGPQALRDAVGRHIASGHNQYSPMTGLPALRQQIAAKIARSYGA
NVDADTEVTVTPGATQAIFCAIQAVIRTGDEVIVFDPAYDSYEPAVELAGGRCVHVQLGLKDFSIDFDRLSAALSPRTRM
IILNTPHNPSGALISRAELDQLAALIRDRDIYVISDEVYEHLVFDGVPHVSVLAHEELYQRAFVVSSFGKTYHVTGWKTG
YVVAPPALTAELRKVHQYVSFCGVTPLQYALADYMAEHPEHVEELPGFYQAKRDLFCDLLAPSRFSFTRVTGTYFQLVDY
SQIRPDLNDVEMAMWMTREHGVASIPVSVFYQHPPEGQRLVRLCFAKREETLREAAAKLCVI
>Mature_382_residues
MITSKLPNVGITIFTQMSQLAAQTGAINLSQGFPDFDGPQALRDAVGRHIASGHNQYSPMTGLPALRQQIAAKIARSYGA
NVDADTEVTVTPGATQAIFCAIQAVIRTGDEVIVFDPAYDSYEPAVELAGGRCVHVQLGLKDFSIDFDRLSAALSPRTRM
IILNTPHNPSGALISRAELDQLAALIRDRDIYVISDEVYEHLVFDGVPHVSVLAHEELYQRAFVVSSFGKTYHVTGWKTG
YVVAPPALTAELRKVHQYVSFCGVTPLQYALADYMAEHPEHVEELPGFYQAKRDLFCDLLAPSRFSFTRVTGTYFQLVDY
SQIRPDLNDVEMAMWMTREHGVASIPVSVFYQHPPEGQRLVRLCFAKREETLREAAAKLCVI

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=392, Percent_Identity=34.6938775510204, Blast_Score=231, Evalue=7e-61,
Organism=Homo sapiens, GI56713256, Length=392, Percent_Identity=34.6938775510204, Blast_Score=231, Evalue=7e-61,
Organism=Homo sapiens, GI95147551, Length=408, Percent_Identity=32.843137254902, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI169881279, Length=408, Percent_Identity=32.843137254902, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI169881281, Length=408, Percent_Identity=28.6764705882353, Blast_Score=165, Evalue=8e-41,
Organism=Homo sapiens, GI4507369, Length=376, Percent_Identity=24.2021276595745, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1786816, Length=376, Percent_Identity=55.0531914893617, Blast_Score=414, Evalue=1e-117,
Organism=Escherichia coli, GI1788722, Length=379, Percent_Identity=23.7467018469657, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1788627, Length=289, Percent_Identity=26.643598615917, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1787710, Length=277, Percent_Identity=25.9927797833935, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790797, Length=328, Percent_Identity=24.390243902439, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71994472, Length=397, Percent_Identity=34.2569269521411, Blast_Score=230, Evalue=8e-61,
Organism=Caenorhabditis elegans, GI71994476, Length=397, Percent_Identity=34.2569269521411, Blast_Score=230, Evalue=8e-61,
Organism=Caenorhabditis elegans, GI17567369, Length=398, Percent_Identity=32.4120603015075, Blast_Score=217, Evalue=7e-57,
Organism=Caenorhabditis elegans, GI17567663, Length=208, Percent_Identity=25, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322401, Length=389, Percent_Identity=32.9048843187661, Blast_Score=202, Evalue=1e-52,
Organism=Drosophila melanogaster, GI28573069, Length=399, Percent_Identity=33.3333333333333, Blast_Score=222, Evalue=3e-58,
Organism=Drosophila melanogaster, GI24646114, Length=399, Percent_Identity=33.3333333333333, Blast_Score=222, Evalue=3e-58,
Organism=Drosophila melanogaster, GI28573067, Length=399, Percent_Identity=33.3333333333333, Blast_Score=222, Evalue=3e-58,
Organism=Drosophila melanogaster, GI28573065, Length=399, Percent_Identity=33.3333333333333, Blast_Score=222, Evalue=3e-58,
Organism=Drosophila melanogaster, GI18859735, Length=343, Percent_Identity=24.198250728863, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 42308; Mature: 42308

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITSKLPNVGITIFTQMSQLAAQTGAINLSQGFPDFDGPQALRDAVGRHIASGHNQYSPM
CCCCCCCCCCCHHHHHHHHHHHHHCCEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
TGLPALRQQIAAKIARSYGANVDADTEVTVTPGATQAIFCAIQAVIRTGDEVIVFDPAYD
CCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCC
SYEPAVELAGGRCVHVQLGLKDFSIDFDRLSAALSPRTRMIILNTPHNPSGALISRAELD
CCCCHHHHCCCEEEEEEECCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCCEEHHHHH
QLAALIRDRDIYVISDEVYEHLVFDGVPHVSVLAHEELYQRAFVVSSFGKTYHVTGWKTG
HHHHHHHCCCEEEECHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCC
YVVAPPALTAELRKVHQYVSFCGVTPLQYALADYMAEHPEHVEELPGFYQAKRDLFCDLL
EEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHC
APSRFSFTRVTGTYFQLVDYSQIRPDLNDVEMAMWMTREHGVASIPVSVFYQHPPEGQRL
CCCCCEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEECCCEEEECCCCCHHHH
VRLCFAKREETLREAAAKLCVI
HHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MITSKLPNVGITIFTQMSQLAAQTGAINLSQGFPDFDGPQALRDAVGRHIASGHNQYSPM
CCCCCCCCCCCHHHHHHHHHHHHHCCEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
TGLPALRQQIAAKIARSYGANVDADTEVTVTPGATQAIFCAIQAVIRTGDEVIVFDPAYD
CCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCC
SYEPAVELAGGRCVHVQLGLKDFSIDFDRLSAALSPRTRMIILNTPHNPSGALISRAELD
CCCCHHHHCCCEEEEEEECCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCCEEHHHHH
QLAALIRDRDIYVISDEVYEHLVFDGVPHVSVLAHEELYQRAFVVSSFGKTYHVTGWKTG
HHHHHHHCCCEEEECHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCC
YVVAPPALTAELRKVHQYVSFCGVTPLQYALADYMAEHPEHVEELPGFYQAKRDLFCDLL
EEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHC
APSRFSFTRVTGTYFQLVDYSQIRPDLNDVEMAMWMTREHGVASIPVSVFYQHPPEGQRL
CCCCCEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEECCCEEEECCCCCHHHH
VRLCFAKREETLREAAAKLCVI
HHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]