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The map label for this gene is glpR [H]

Identifier: 77460754

GI number: 77460754

Start: 5107303

End: 5108058

Strand: Direct

Name: glpR [H]

Synonym: Pfl01_4533

Alternate gene names: 77460754

Gene position: 5107303-5108058 (Clockwise)

Preceding gene: 77460753

Following gene: 77460755

Centisome position: 79.33

GC content: 59.92

Gene sequence:

>756_bases
ATGAATCTGCCTCCCCGTCAGCAGCAAATCCTCGAACTGGTCCGCGAACGCGGCTATGTGAGCATCGAGGAAATGGCCAC
GCTGTTCGTTGTTACCCCGCAAACCATCCGCCGCGATATCAATCAACTGGCGGAAGCCAATCTGCTGCGTCGCTACCACG
GCGGCGCCGCCTATGATTCCAGTGTCGAAAACACTGCCTACGCGATGCGCGCCGATCAGATGCGCGATGAAAAGCAACGC
ATCGGCGAAGCCATTGCCGCGCAAATTCCCGATCACGCCTCGCTGTTCATCAACATCGGCACCACCACCGAATCGATTGC
CCGCGCCCTGCTCAATCACAGCCATCTGAAGATCATCACCAACAACCTGCACGTCGCCTCGATGCTCAGTGCCAAGGATG
ATTTCGATGTGCTGCTGACCGGCGGCAATGTGCGTCGCGATGGCGGCGTGGTGGGCCAGGCGAGCGTGGACTTCATCAAT
CAGTTCAAGGTCGACTTTGCGCTGGTGGGCATCAGCGGCATCGACGAAGACGGCAGCCTGCTCGACTTCGATTACCAGGA
AGTGCGGGTGTCCCAGGCGATCATCGCCAATGCCCGGCAGGTGATCCTGGCGGCGGACTCCAGCAAGTTCGGCCGTAACG
CGATGATCCGCCTCGGCCCGATCAGCCTGATCGATTGCCTGGTGACCGATCAGCAGCCGGTGCCAGCCCTGGCGCAACTG
CTGAGCCAGCACAAGATTCGCCTGGAAGTCGTTTAA

Upstream 100 bases:

>100_bases
AATAAGCCAACCTGAGTACTCGTATCCGTATGTAACTGGTAGGGAGCGGATTCCTGCGGCATCATGGGCAAATTTTGCAC
GGCAGCCCAAAGGAAGCCCC

Downstream 100 bases:

>100_bases
CCCTCTCCTCCGCATAAGGCGCCTGCACCGGCGCCCTATGCTCATCTGATGTTCGAATATTTTCCTTTCTCCATCCTTCG
ATGAGTTTTTTCAATCGAAG

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MNLPPRQQQILELVRERGYVSIEEMATLFVVTPQTIRRDINQLAEANLLRRYHGGAAYDSSVENTAYAMRADQMRDEKQR
IGEAIAAQIPDHASLFINIGTTTESIARALLNHSHLKIITNNLHVASMLSAKDDFDVLLTGGNVRRDGGVVGQASVDFIN
QFKVDFALVGISGIDEDGSLLDFDYQEVRVSQAIIANARQVILAADSSKFGRNAMIRLGPISLIDCLVTDQQPVPALAQL
LSQHKIRLEVV

Sequences:

>Translated_251_residues
MNLPPRQQQILELVRERGYVSIEEMATLFVVTPQTIRRDINQLAEANLLRRYHGGAAYDSSVENTAYAMRADQMRDEKQR
IGEAIAAQIPDHASLFINIGTTTESIARALLNHSHLKIITNNLHVASMLSAKDDFDVLLTGGNVRRDGGVVGQASVDFIN
QFKVDFALVGISGIDEDGSLLDFDYQEVRVSQAIIANARQVILAADSSKFGRNAMIRLGPISLIDCLVTDQQPVPALAQL
LSQHKIRLEVV
>Mature_251_residues
MNLPPRQQQILELVRERGYVSIEEMATLFVVTPQTIRRDINQLAEANLLRRYHGGAAYDSSVENTAYAMRADQMRDEKQR
IGEAIAAQIPDHASLFINIGTTTESIARALLNHSHLKIITNNLHVASMLSAKDDFDVLLTGGNVRRDGGVVGQASVDFIN
QFKVDFALVGISGIDEDGSLLDFDYQEVRVSQAIIANARQVILAADSSKFGRNAMIRLGPISLIDCLVTDQQPVPALAQL
LSQHKIRLEVV

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=252, Percent_Identity=53.968253968254, Blast_Score=289, Evalue=2e-79,
Organism=Escherichia coli, GI87082344, Length=245, Percent_Identity=42.0408163265306, Blast_Score=215, Evalue=3e-57,
Organism=Escherichia coli, GI1789059, Length=248, Percent_Identity=31.4516129032258, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1788069, Length=251, Percent_Identity=27.0916334661355, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI226510968, Length=233, Percent_Identity=30.4721030042918, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789519, Length=240, Percent_Identity=26.25, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1787540, Length=250, Percent_Identity=27.2, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790635, Length=238, Percent_Identity=25.6302521008403, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790753, Length=240, Percent_Identity=25, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789170, Length=233, Percent_Identity=23.6051502145923, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787063, Length=248, Percent_Identity=24.5967741935484, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27676; Mature: 27676

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLPPRQQQILELVRERGYVSIEEMATLFVVTPQTIRRDINQLAEANLLRRYHGGAAYDS
CCCCHHHHHHHHHHHHCCCEEHHHHEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SVENTAYAMRADQMRDEKQRIGEAIAAQIPDHASLFINIGTTTESIARALLNHSHLKIIT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCEEEEE
NNLHVASMLSAKDDFDVLLTGGNVRRDGGVVGQASVDFINQFKVDFALVGISGIDEDGSL
CCCCEEHHHCCCCCCEEEEECCCEECCCCEECCHHHHHHHHHEEEEEEEEECCCCCCCCE
LDFDYQEVRVSQAIIANARQVILAADSSKFGRNAMIRLGPISLIDCLVTDQQPVPALAQL
ECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEECCHHHHHHHHCCCCCHHHHHHH
LSQHKIRLEVV
HHCCCEEEEEC
>Mature Secondary Structure
MNLPPRQQQILELVRERGYVSIEEMATLFVVTPQTIRRDINQLAEANLLRRYHGGAAYDS
CCCCHHHHHHHHHHHHCCCEEHHHHEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SVENTAYAMRADQMRDEKQRIGEAIAAQIPDHASLFINIGTTTESIARALLNHSHLKIIT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCEEEEE
NNLHVASMLSAKDDFDVLLTGGNVRRDGGVVGQASVDFINQFKVDFALVGISGIDEDGSL
CCCCEEHHHCCCCCCEEEEECCCEECCCCEECCHHHHHHHHHEEEEEEEEECCCCCCCCE
LDFDYQEVRVSQAIIANARQVILAADSSKFGRNAMIRLGPISLIDCLVTDQQPVPALAQL
ECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEECCHHHHHHHHCCCCCHHHHHHH
LSQHKIRLEVV
HHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8752340; 10984043 [H]