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The map label for this gene is ltrA [H]

Identifier: 77460696

GI number: 77460696

Start: 5047032

End: 5047937

Strand: Direct

Name: ltrA [H]

Synonym: Pfl01_4475

Alternate gene names: 77460696

Gene position: 5047032-5047937 (Clockwise)

Preceding gene: 77460693

Following gene: 77460697

Centisome position: 78.39

GC content: 64.9

Gene sequence:

>906_bases
ATGGATCGTCTCCAAGCAATGCGGGTATTCGTCACGGTAGTGGATCTGGGCAGCCAGTCGGCGGCGGCCGATCACCTGGA
CCTGTCACGGCCGGTGGTGTCGCGCTATCTGGCGGAACTGGAAGACTGGGTCGGCGCGCGCCTGATGCACCGCACCACGC
GCAAGTTGAGTTTGACCACCGCCGGCAACGAAATCCTGCCGCGCTGCCGGCAGATGCTGGATCTGTCCGGCGACATGCAG
GCCGCTGTCAGCGAACCTGCCGATGCCCCGCGAGGATTGCTGCGAATCAGCGTCAGCACCTCGTTCGGTCAGGCGCAACT
GGCCGATGCCATGGCGGCGTTTGTCAAAGCCTATCCGGGGGTGAACATCGACCTGCAAATGCTCGATCGCACCGTGAACC
TGGTGGACGAGCGCATCGACCTGGCGATCCGCACCAGCAACGACCTCGACCCCAACCTGATCGCCCGGCGCCTGACGGTG
TGCCGCTCGGTGGTCTGCGCCGCACCCGCCTATCTGCAGGAGCATCCACAGCCGCAGCGCGTAGAAGATCTGAGCCGGCA
CAACTGCCTGACCCATTCCTATTTCGGCAAGAGCCTGTGGCATTTCGAGGAGGACGGCGAACCGGTCTCGGTGCCGGTGC
AGGGCAACATCAGCGCCAACGAGGCCAGCACCCTGCTGCGCGCGACCCTGGCCGGCGCCGGCGTGGCGATGCTGCCGACC
TATCTGGCCGGGGCACATATTCACAGCGGCGAACTGGTGCGCCTGCTGCCCCACGCCGAGCCCCGGCAGATGAGCATCTA
TGCCGTGTATGCCTCGCGCAAGCACATGCCGGCGGCGTTGCGCTGCATGCTGGACTTTCTGGTGCAGCGTTTTCCCGAAA
ACCCGCAGTGGGATATCGGACTGTAA

Upstream 100 bases:

>100_bases
TCGTATGCCGTGCTTGGCGATGGGGACAAAGCTTAGTTGCCAGACTCGTTACAAAAAATGCGATGCTTGGACATAGTTTG
TTTCTGAAAGCGGGCAAATC

Downstream 100 bases:

>100_bases
AGCCGTTCACAGAGCCGCTGGCAACTCCACGGCGCTGACCTATGCTGAAAGTAGTACCCAAGGGTATTCGTTCAGAGGTC
AACGCCATGAACACCAGAAC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MDRLQAMRVFVTVVDLGSQSAAADHLDLSRPVVSRYLAELEDWVGARLMHRTTRKLSLTTAGNEILPRCRQMLDLSGDMQ
AAVSEPADAPRGLLRISVSTSFGQAQLADAMAAFVKAYPGVNIDLQMLDRTVNLVDERIDLAIRTSNDLDPNLIARRLTV
CRSVVCAAPAYLQEHPQPQRVEDLSRHNCLTHSYFGKSLWHFEEDGEPVSVPVQGNISANEASTLLRATLAGAGVAMLPT
YLAGAHIHSGELVRLLPHAEPRQMSIYAVYASRKHMPAALRCMLDFLVQRFPENPQWDIGL

Sequences:

>Translated_301_residues
MDRLQAMRVFVTVVDLGSQSAAADHLDLSRPVVSRYLAELEDWVGARLMHRTTRKLSLTTAGNEILPRCRQMLDLSGDMQ
AAVSEPADAPRGLLRISVSTSFGQAQLADAMAAFVKAYPGVNIDLQMLDRTVNLVDERIDLAIRTSNDLDPNLIARRLTV
CRSVVCAAPAYLQEHPQPQRVEDLSRHNCLTHSYFGKSLWHFEEDGEPVSVPVQGNISANEASTLLRATLAGAGVAMLPT
YLAGAHIHSGELVRLLPHAEPRQMSIYAVYASRKHMPAALRCMLDFLVQRFPENPQWDIGL
>Mature_301_residues
MDRLQAMRVFVTVVDLGSQSAAADHLDLSRPVVSRYLAELEDWVGARLMHRTTRKLSLTTAGNEILPRCRQMLDLSGDMQ
AAVSEPADAPRGLLRISVSTSFGQAQLADAMAAFVKAYPGVNIDLQMLDRTVNLVDERIDLAIRTSNDLDPNLIARRLTV
CRSVVCAAPAYLQEHPQPQRVEDLSRHNCLTHSYFGKSLWHFEEDGEPVSVPVQGNISANEASTLLRATLAGAGVAMLPT
YLAGAHIHSGELVRLLPHAEPRQMSIYAVYASRKHMPAALRCMLDFLVQRFPENPQWDIGL

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081978, Length=296, Percent_Identity=34.4594594594595, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1789440, Length=283, Percent_Identity=31.095406360424, Blast_Score=158, Evalue=3e-40,
Organism=Escherichia coli, GI1789639, Length=294, Percent_Identity=32.9931972789116, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI1786401, Length=294, Percent_Identity=31.9727891156463, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI145693193, Length=294, Percent_Identity=29.2517006802721, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1787128, Length=285, Percent_Identity=28.4210526315789, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1787589, Length=283, Percent_Identity=26.8551236749117, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1789173, Length=250, Percent_Identity=26.4, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1790011, Length=294, Percent_Identity=22.7891156462585, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788706, Length=257, Percent_Identity=26.8482490272374, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787879, Length=155, Percent_Identity=29.6774193548387, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI157672245, Length=121, Percent_Identity=32.2314049586777, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33261; Mature: 33261

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRLQAMRVFVTVVDLGSQSAAADHLDLSRPVVSRYLAELEDWVGARLMHRTTRKLSLTT
CCHHHHHHHHHHHHHCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEC
AGNEILPRCRQMLDLSGDMQAAVSEPADAPRGLLRISVSTSFGQAQLADAMAAFVKAYPG
CCHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCC
VNIDLQMLDRTVNLVDERIDLAIRTSNDLDPNLIARRLTVCRSVVCAAPAYLQEHPQPQR
CCEEHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCHH
VEDLSRHNCLTHSYFGKSLWHFEEDGEPVSVPVQGNISANEASTLLRATLAGAGVAMLPT
HHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHH
YLAGAHIHSGELVRLLPHAEPRQMSIYAVYASRKHMPAALRCMLDFLVQRFPENPQWDIG
HHHCCEECCCCEEEECCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCC
L
C
>Mature Secondary Structure
MDRLQAMRVFVTVVDLGSQSAAADHLDLSRPVVSRYLAELEDWVGARLMHRTTRKLSLTT
CCHHHHHHHHHHHHHCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEC
AGNEILPRCRQMLDLSGDMQAAVSEPADAPRGLLRISVSTSFGQAQLADAMAAFVKAYPG
CCHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCC
VNIDLQMLDRTVNLVDERIDLAIRTSNDLDPNLIARRLTVCRSVVCAAPAYLQEHPQPQR
CCEEHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCHH
VEDLSRHNCLTHSYFGKSLWHFEEDGEPVSVPVQGNISANEASTLLRATLAGAGVAMLPT
HHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHH
YLAGAHIHSGELVRLLPHAEPRQMSIYAVYASRKHMPAALRCMLDFLVQRFPENPQWDIG
HHHCCEECCCCEEEECCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCC
L
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8748036 [H]