Click here to switch to the map view.

The map label for this gene is potC [H]

Identifier: 77460688

GI number: 77460688

Start: 5037901

End: 5038749

Strand: Reverse

Name: potC [H]

Synonym: Pfl01_4467

Alternate gene names: 77460688

Gene position: 5038749-5037901 (Counterclockwise)

Preceding gene: 77460689

Following gene: 77460687

Centisome position: 78.26

GC content: 61.6

Gene sequence:

>849_bases
ATGAGTGCCCTGATCAAGAAGCGTCAGTCGCTGTTGCCGGGCGACACCGGCAAGTTCGCCGGCATCCTGTCCGGGATCAT
TTTGTTCCTGGCCGTGTTGCCGATCCTGACCATGATCGTGATGTCGTTCAGCGGCGCGTCGAACCTCGACTTCCCGCCGA
GCAGCTACAGCCTGCAGTGGTACAAGGCGGCGTGGCACACCTTCGTCTCGCCGGATGCCAGCGATGTGCTGAGCCTCGGC
CAGGCCATGGGCACCAGTTTGCTGGTGTCGTGCCTGACGATGATTTTCGCCACGCTGATCGCGGTGCCGGCGGCCTACGC
GCTGACCCGTTGCGAGTTCCGTGGCAAGGGCGTGGCGCTGCAATTGATGTCGCTGCCGCTGGTGTTCCCGATGGTGGTGC
TGGGGCTGGCCTTGCTGCTGGTGTTCGACAGCCTGCCGTTCCACATGACCACCTCGCGACTGGTGATTGCCCACGTGATT
CTGGCGCTGCCGTTCGTGGTGAAGAACTGCACGGCGGCCATGCTTTCCATCGGCAGCGAAGTCGAAGAGGCCGCGCAGAT
GCTCGGCGCCTCGCCGTTGCGCGCCATCGTCGATGTGGTGGTGCCGCTGATGAAATCGGGGATTCTGGCGGGGATGCTGC
TGGCGTTCATCGTCTCGTTCAACGAATTCACCGTGACCTATTTCCTCTACACCATTGACGTCATGACCGTGCCGATCTGG
ATGTACAGCCGCACCGTGTCATCGCTCGACCCTACCGTGTTTTCGTTTGCCGTGCTGATCGTGCTGATCGACTTCGTCCT
GATCTGGGCGTTGGAGAAACTGGTCGGCGAGGGTGGCGTTTCCTTCTGA

Upstream 100 bases:

>100_bases
CGTCCGCCGCCGGGGTGGTGCTGATCGTCACTACGCTCGCCATCATGACCTTGTCCGAATACATCACCGGCCGCCGTCGC
CGTCTGCTGGAGGCTTCGCA

Downstream 100 bases:

>100_bases
TTTTGAGGTGATTTTTATGTCTGGTCTGATTCTGGAAAACGTCGAGAAACACTACGGCTCGGCCTGCGCGGTAAAAGACG
TCAACCTGCATTTGCCCGAG

Product: binding-protein dependent transport system inner membrane protein

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MSALIKKRQSLLPGDTGKFAGILSGIILFLAVLPILTMIVMSFSGASNLDFPPSSYSLQWYKAAWHTFVSPDASDVLSLG
QAMGTSLLVSCLTMIFATLIAVPAAYALTRCEFRGKGVALQLMSLPLVFPMVVLGLALLLVFDSLPFHMTTSRLVIAHVI
LALPFVVKNCTAAMLSIGSEVEEAAQMLGASPLRAIVDVVVPLMKSGILAGMLLAFIVSFNEFTVTYFLYTIDVMTVPIW
MYSRTVSSLDPTVFSFAVLIVLIDFVLIWALEKLVGEGGVSF

Sequences:

>Translated_282_residues
MSALIKKRQSLLPGDTGKFAGILSGIILFLAVLPILTMIVMSFSGASNLDFPPSSYSLQWYKAAWHTFVSPDASDVLSLG
QAMGTSLLVSCLTMIFATLIAVPAAYALTRCEFRGKGVALQLMSLPLVFPMVVLGLALLLVFDSLPFHMTTSRLVIAHVI
LALPFVVKNCTAAMLSIGSEVEEAAQMLGASPLRAIVDVVVPLMKSGILAGMLLAFIVSFNEFTVTYFLYTIDVMTVPIW
MYSRTVSSLDPTVFSFAVLIVLIDFVLIWALEKLVGEGGVSF
>Mature_281_residues
SALIKKRQSLLPGDTGKFAGILSGIILFLAVLPILTMIVMSFSGASNLDFPPSSYSLQWYKAAWHTFVSPDASDVLSLGQ
AMGTSLLVSCLTMIFATLIAVPAAYALTRCEFRGKGVALQLMSLPLVFPMVVLGLALLLVFDSLPFHMTTSRLVIAHVIL
ALPFVVKNCTAAMLSIGSEVEEAAQMLGASPLRAIVDVVVPLMKSGILAGMLLAFIVSFNEFTVTYFLYTIDVMTVPIWM
YSRTVSSLDPTVFSFAVLIVLIDFVLIWALEKLVGEGGVSF

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=225, Percent_Identity=26.6666666666667, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787714, Length=240, Percent_Identity=30.8333333333333, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788764, Length=160, Percent_Identity=30, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787081, Length=235, Percent_Identity=27.2340425531915, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30401; Mature: 30270

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SALIKKRQSLLPGDTGKFAGILSGIILFLAVLPILTMIVMSFSGASNLDFPPSSYSLQW
CHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
YKAAWHTFVSPDASDVLSLGQAMGTSLLVSCLTMIFATLIAVPAAYALTRCEFRGKGVAL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
QLMSLPLVFPMVVLGLALLLVFDSLPFHMTTSRLVIAHVILALPFVVKNCTAAMLSIGSE
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEEAAQMLGASPLRAIVDVVVPLMKSGILAGMLLAFIVSFNEFTVTYFLYTIDVMTVPIW
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MYSRTVSSLDPTVFSFAVLIVLIDFVLIWALEKLVGEGGVSF
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]