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The map label for this gene is sbcB [H]

Identifier: 77460659

GI number: 77460659

Start: 4997582

End: 4999012

Strand: Reverse

Name: sbcB [H]

Synonym: Pfl01_4438

Alternate gene names: 77460659

Gene position: 4999012-4997582 (Counterclockwise)

Preceding gene: 77460667

Following gene: 77460657

Centisome position: 77.64

GC content: 58.98

Gene sequence:

>1431_bases
GTGACTTCCATCTTCTGGTACGACTACGAAACCACCGGCATCAACCCCCGATGCGACCGTCCGTTGCAGGTGGCCGGGAT
CCGCACCGACCACGAACTCAACGAAATCGACGCGCCGGTCAATCTCTACTGCCAGCCCAGCGAAGACATCCTGCCGCATC
CGGCGGCGTGCGCGATCACCGGCATTACCCCGAGCCGCCTCGCCGAGCAAGGTTTGAGCGAAGCCGACTTCATGACCCGG
GTTCACGCGCAGCTCGCGGCTCCCGGCACCTGCGGTGCGGGGTACAACACCTTGCGCTTTGACGACGAGATGACCCGCTA
CAGCCTGTACCGCAACTTTTTCGATCCCTATGCCCGTGAATGGCAGGGCGGCAACAGTCGCTGGGACCTGATTGACGTAG
TACGCGCCGCCTACGCGTTGCGCCCGGACGGGCTGGTCTGGCCGACCGATGACGAAGGCAAGGTGACGCTCAAGCTCGAA
CGTCTGACCGCCGCCAACAACATCGATCATGGCAATGCCCACGAAGCCCTGTCGGACGTGCGCGCCACCATTGCCCTGGC
CCGGTTGATCCGCGAGAAGCAGCCGAAGCTGTATGACTGGTTGTTCCAGCTGCGCAGCAAGCAGAAGGTCATGGACCAGA
TTCGTCTGTTGCAGCCGATGGTGCACATTTCCGGCCGCTTCTCGGCTGCGCGCAGTTATGTTGGTGTGGTGCTGCCGCTG
GCCTGGCATCCGCGCAACAAGAACGCGTTGATCGTCTGTGACCTGCACCTGGACCCGCAGGGGCTGCTCGACCTGGATGC
CGAAACATTGCGTCAGCGCCTGTATACCCGGCGTGACGACCTGGCCGAAGGCGAGTTGCCGGTACCGCTCAAACTCATCC
ATATCAACAAGTGTCCGGTGGTGGCGCCATTGTCGGTGTTGCGTGCTGACGATCAGCAGCGCCTGGGTCTGGACATGGCC
TTGTATCAGGCGCGCGCCTTGCGACTAAGTGACGCACAACAAGTTTGGAAAGATAAAGTCTCGGCGATTTATGCCAGCGA
AGATTTCACCTCGAATGAAGATCCCGAACAACAGTTGTACGACGGATTTATCGGTGATCGTGATCGTCGTTTATGTGAGC
AAGTGAGGGCGACCGATCCTGGCCAATTGGCGCGAGAGCAATGGCCGTTCGATGACGAACGTTTGCCTGAATTGTTGTTT
CGATATCGAGCACGTAACTTTCCCGATACGTTGAATTTCGAAGAGCAAGAGCGCTGGAGAATCTTTTGCCGGCAACGCTT
GTCAGCGCCGGAGTGGGGGGCGCCTAATACCTTGCAATCTTTTGCCGAGGCCATGGAGCAATGGCTGCTTAGTGCTGCGC
CGATGCAGGCCGAGGTGTTGGTTGAATGGCAGAACTATGTCCAGGCATTGCGCAAACGTTTGGATCTTTGA

Upstream 100 bases:

>100_bases
CATACACATCCTTCAACCAAAGGTGACTGAATGATGCGGTGCTGGCCGCGACGGCGGTCGAACGCCTAGACTTTGCCGAT
CTTCAGTTCAGGAACCGCCC

Downstream 100 bases:

>100_bases
AATCGAACATATCCGGCGCTTGAATGCCGGGCATAAAAAAACGCCAGCATTCGCTGGCGTTTTTTTGTGTCACAGAAGCG
CTCTGCGACAAGGGTTGCGG

Product: exonuclease I

Products: NA

Alternate protein names: Exonuclease I; DNA deoxyribophosphodiesterase; dRPase [H]

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MTSIFWYDYETTGINPRCDRPLQVAGIRTDHELNEIDAPVNLYCQPSEDILPHPAACAITGITPSRLAEQGLSEADFMTR
VHAQLAAPGTCGAGYNTLRFDDEMTRYSLYRNFFDPYAREWQGGNSRWDLIDVVRAAYALRPDGLVWPTDDEGKVTLKLE
RLTAANNIDHGNAHEALSDVRATIALARLIREKQPKLYDWLFQLRSKQKVMDQIRLLQPMVHISGRFSAARSYVGVVLPL
AWHPRNKNALIVCDLHLDPQGLLDLDAETLRQRLYTRRDDLAEGELPVPLKLIHINKCPVVAPLSVLRADDQQRLGLDMA
LYQARALRLSDAQQVWKDKVSAIYASEDFTSNEDPEQQLYDGFIGDRDRRLCEQVRATDPGQLAREQWPFDDERLPELLF
RYRARNFPDTLNFEEQERWRIFCRQRLSAPEWGAPNTLQSFAEAMEQWLLSAAPMQAEVLVEWQNYVQALRKRLDL

Sequences:

>Translated_476_residues
MTSIFWYDYETTGINPRCDRPLQVAGIRTDHELNEIDAPVNLYCQPSEDILPHPAACAITGITPSRLAEQGLSEADFMTR
VHAQLAAPGTCGAGYNTLRFDDEMTRYSLYRNFFDPYAREWQGGNSRWDLIDVVRAAYALRPDGLVWPTDDEGKVTLKLE
RLTAANNIDHGNAHEALSDVRATIALARLIREKQPKLYDWLFQLRSKQKVMDQIRLLQPMVHISGRFSAARSYVGVVLPL
AWHPRNKNALIVCDLHLDPQGLLDLDAETLRQRLYTRRDDLAEGELPVPLKLIHINKCPVVAPLSVLRADDQQRLGLDMA
LYQARALRLSDAQQVWKDKVSAIYASEDFTSNEDPEQQLYDGFIGDRDRRLCEQVRATDPGQLAREQWPFDDERLPELLF
RYRARNFPDTLNFEEQERWRIFCRQRLSAPEWGAPNTLQSFAEAMEQWLLSAAPMQAEVLVEWQNYVQALRKRLDL
>Mature_475_residues
TSIFWYDYETTGINPRCDRPLQVAGIRTDHELNEIDAPVNLYCQPSEDILPHPAACAITGITPSRLAEQGLSEADFMTRV
HAQLAAPGTCGAGYNTLRFDDEMTRYSLYRNFFDPYAREWQGGNSRWDLIDVVRAAYALRPDGLVWPTDDEGKVTLKLER
LTAANNIDHGNAHEALSDVRATIALARLIREKQPKLYDWLFQLRSKQKVMDQIRLLQPMVHISGRFSAARSYVGVVLPLA
WHPRNKNALIVCDLHLDPQGLLDLDAETLRQRLYTRRDDLAEGELPVPLKLIHINKCPVVAPLSVLRADDQQRLGLDMAL
YQARALRLSDAQQVWKDKVSAIYASEDFTSNEDPEQQLYDGFIGDRDRRLCEQVRATDPGQLAREQWPFDDERLPELLFR
YRARNFPDTLNFEEQERWRIFCRQRLSAPEWGAPNTLQSFAEAMEQWLLSAAPMQAEVLVEWQNYVQALRKRLDL

Specific function: Also functions as a DNA deoxyribophosphodiesterase that releases deoxyribose-phosphate moieties following the cleavage DNA at an apurinic/apyrimidinic (AP) site by either an AP endonuclease AP lyase [H]

COG id: COG2925

COG function: function code L; Exonuclease I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788321, Length=448, Percent_Identity=47.7678571428571, Blast_Score=420, Evalue=1e-118,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013620
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T; PF08411 Exonuc_X-T_C [H]

EC number: =3.1.11.1 [H]

Molecular weight: Translated: 54749; Mature: 54617

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSIFWYDYETTGINPRCDRPLQVAGIRTDHELNEIDAPVNLYCQPSEDILPHPAACAIT
CCCEEEEECEECCCCCCCCCCEEEECCCCCCHHHHCCCCEEEEECCCCCCCCCCCCEEEE
GITPSRLAEQGLSEADFMTRVHAQLAAPGTCGAGYNTLRFDDEMTRYSLYRNFFDPYARE
CCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHH
WQGGNSRWDLIDVVRAAYALRPDGLVWPTDDEGKVTLKLERLTAANNIDHGNAHEALSDV
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEHHHCCCCCCCHHHHHHHH
RATIALARLIREKQPKLYDWLFQLRSKQKVMDQIRLLQPMVHISGRFSAARSYVGVVLPL
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEEEE
AWHPRNKNALIVCDLHLDPQGLLDLDAETLRQRLYTRRDDLAEGELPVPLKLIHINKCPV
EECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCC
VAPLSVLRADDQQRLGLDMALYQARALRLSDAQQVWKDKVSAIYASEDFTSNEDPEQQLY
HHHHHHHHCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHH
DGFIGDRDRRLCEQVRATDPGQLAREQWPFDDERLPELLFRYRARNFPDTLNFEEQERWR
HCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
IFCRQRLSAPEWGAPNTLQSFAEAMEQWLLSAAPMQAEVLVEWQNYVQALRKRLDL
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TSIFWYDYETTGINPRCDRPLQVAGIRTDHELNEIDAPVNLYCQPSEDILPHPAACAIT
CCEEEEECEECCCCCCCCCCEEEECCCCCCHHHHCCCCEEEEECCCCCCCCCCCCEEEE
GITPSRLAEQGLSEADFMTRVHAQLAAPGTCGAGYNTLRFDDEMTRYSLYRNFFDPYARE
CCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHH
WQGGNSRWDLIDVVRAAYALRPDGLVWPTDDEGKVTLKLERLTAANNIDHGNAHEALSDV
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEHHHCCCCCCCHHHHHHHH
RATIALARLIREKQPKLYDWLFQLRSKQKVMDQIRLLQPMVHISGRFSAARSYVGVVLPL
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEEEE
AWHPRNKNALIVCDLHLDPQGLLDLDAETLRQRLYTRRDDLAEGELPVPLKLIHINKCPV
EECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCC
VAPLSVLRADDQQRLGLDMALYQARALRLSDAQQVWKDKVSAIYASEDFTSNEDPEQQLY
HHHHHHHHCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHH
DGFIGDRDRRLCEQVRATDPGQLAREQWPFDDERLPELLFRYRARNFPDTLNFEEQERWR
HCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
IFCRQRLSAPEWGAPNTLQSFAEAMEQWLLSAAPMQAEVLVEWQNYVQALRKRLDL
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3539937; 9097040; 9278503; 1329027 [H]