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The map label for this gene is atoS [H]

Identifier: 77460644

GI number: 77460644

Start: 4979890

End: 4981926

Strand: Direct

Name: atoS [H]

Synonym: Pfl01_4423

Alternate gene names: 77460644

Gene position: 4979890-4981926 (Clockwise)

Preceding gene: 77460643

Following gene: 77460645

Centisome position: 77.35

GC content: 62.69

Gene sequence:

>2037_bases
ATGCCATTGCGCCAGCGTCTTGAAAACCTGCCGGTCGGCCAGAAACTGCTGGCCGCCCTGCTGGTGCTGTTGACCACCGT
GTTGCTGGTCGCCAACCTGACCTTTATCAGCGCCGCCTATTACATTTCCCAGGAAAGCATGGCGCCCCAGGCGTTGCAGA
CCATCGGCCGGCTGGTGTCGAACCCGAGCCTGGTGGCCGAAGCCTTGCAATCGCCACAAAGCGCCGAGCGTCTGCTCAAG
GAGCTCGACAGCTATTCTCCGCTGCGTGCAGCCGCTTTATATGACGGCAAAGGCGAACGTCTGGCGCAGTTGCAACACGG
CGACAAACTCAACCTGCCGGAACGCTACCGGCACATCGAAGCCTGGCAACTGACCGAGTTTCGCAGCAATCAACTGATCA
CCCTGCCCCGCCCCGGCACCGCGCCGGGCCATCTGTTGCTGGTGGCCAGCAGCGAGCTGCCGGTGGCGTTCTATACCGGC
ACACTCACGGCCAGCCTGGGGATCCTGATTTTCAGTGTGCTGCTGTGGCTGGTCATCGCCCGGCAGATCAAGCGCCTGAT
CACCCGGCCGATTCATCAACTGGAAGAACTGTCCCGTCAGGTAACCCGCGAGGAGAACTATGCCCTGCGCGCCTCCCGGG
GCAACCATGACGAAATCGGCAGCCTCGCCGAAGCGTTCAACACCATGCTGTCGCGCATCGAGGCGAGGGAGCAGCAACTC
AAGCGTGCCCGCGATGATTCCCAGGCGGCTTACGATCAGGCCCAGGGGCTGGCCGAAGAAACCCGCCACACCAACCGCAA
GCTGGAACTGGAAGTCCAGGTGCGCAGCAAGATCGAGAAGAAACTCACCGGGTTCCAGAACTACCTCAACAGCATCATCG
ACTCCATGCCCTCGGCGCTGATCGCCCTCGACGAACAGCTCTACGTCACGCAGTGGAACCAGGAGGCCAGCGCCCTTTCC
GGTACACGACTGGACGAAGCGCTTAACCAGCCGATCTTCCTCGCGTTCGAGCCGCTCAAGCCGTTCCTGCCGCAACTCAA
GCAGACCGTCGAACAGCACACTGTGGCGAAAATCGAGCGGGTGACGTGGTTCAAGGACGACGAGCCCAAGCACTACGCCC
TCACCTTCTACCCGTTGATGGGCGGTGCCGGGCGCGGCGTGGTGATCCGGATCGACGACATCACCCAGCGCCTGTCGCTG
GAAGAAATGATGGTGCAGTCGGAGAAAATGCTGTCGGTCGGTGGCCTCGCCGCCGGCATGGCCCACGAGATCAATAACCC
GCTGGGGGCGATCCTGCACAACGTGCAGAACATTCGCCGACGCCTGTCGCCGGACCTGCCGAAGAACCTCGAGCAGGCCG
AGCAACTGGGCATCGAACTCGATACCGTGAACCGTTATCTGCAAGGCCGGGAAGTCCCGCAACTGCTCGACGGCATTCAG
CAGGCCGGCGCCCGGGCGGCGAAAATCGTCACCCACATGCTCAGTTTCAGCCGTCGCAGCAACCGCCAGATGGCGCCGTG
CGACCTGCCGGCGCTGATCGATCAAGCCGTGGAAATCGCCGGCAACGACTTCGACCTGGCCATCGGCTTCGACTTTAAGG
GGCAGGCGATCATTCGCCAGTTCGACCCGGCGCTGGGCCCGGTGCCCGGCACTGCCAACGAACTGGAACAGGTGCTGCTG
AACCTGCTGAAAAACGCCGCGCAGGCGATCCACCAGCGCGAAGATGACAGCGAGCCAGGGCGAATCACCTTGCGCACCCG
GCTCAATCCGCCGTGGGCCGAGATTCAGGTCGAGGACAACGGCATCGGCATGAGCGAGAACGTGCGCAAGCGCACCTTCG
AGCCGTTCTTCACCACCAAGGAAATCGGCCAGGGCACGGGCCTCGGGCTGTCGGTGTCGTACTTCATCATCACCAACAAC
CACAAAGGCCAGATGGAAGTGCAGTCGGCGCCGGGGCAAGGCACCTGCTTCACCCTGCGCCTGCCACTGGCGCAACCGGC
GCCCATCGCCGCCGAAACCAATCAACTACCGAGGTAA

Upstream 100 bases:

>100_bases
GTTGCAGCAGCGCCTGACTGCCCATCTGCACAGTCTCGGATTGCCCGTCGACTGAGCAGCGGCTACGCTGGCCACTTGTT
CCTTTGCTGCGATAAACCTG

Downstream 100 bases:

>100_bases
ACCATGGGCTTTCGCCTGTCGAAGATCTACACCCGCACCGGCGACAAGGGCGAAACCGGACTCGGCGACGGCCGCCGGGT
GCCCAAGGATCACCCGCGCA

Product: multi-sensor Signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 678; Mature: 677

Protein sequence:

>678_residues
MPLRQRLENLPVGQKLLAALLVLLTTVLLVANLTFISAAYYISQESMAPQALQTIGRLVSNPSLVAEALQSPQSAERLLK
ELDSYSPLRAAALYDGKGERLAQLQHGDKLNLPERYRHIEAWQLTEFRSNQLITLPRPGTAPGHLLLVASSELPVAFYTG
TLTASLGILIFSVLLWLVIARQIKRLITRPIHQLEELSRQVTREENYALRASRGNHDEIGSLAEAFNTMLSRIEAREQQL
KRARDDSQAAYDQAQGLAEETRHTNRKLELEVQVRSKIEKKLTGFQNYLNSIIDSMPSALIALDEQLYVTQWNQEASALS
GTRLDEALNQPIFLAFEPLKPFLPQLKQTVEQHTVAKIERVTWFKDDEPKHYALTFYPLMGGAGRGVVIRIDDITQRLSL
EEMMVQSEKMLSVGGLAAGMAHEINNPLGAILHNVQNIRRRLSPDLPKNLEQAEQLGIELDTVNRYLQGREVPQLLDGIQ
QAGARAAKIVTHMLSFSRRSNRQMAPCDLPALIDQAVEIAGNDFDLAIGFDFKGQAIIRQFDPALGPVPGTANELEQVLL
NLLKNAAQAIHQREDDSEPGRITLRTRLNPPWAEIQVEDNGIGMSENVRKRTFEPFFTTKEIGQGTGLGLSVSYFIITNN
HKGQMEVQSAPGQGTCFTLRLPLAQPAPIAAETNQLPR

Sequences:

>Translated_678_residues
MPLRQRLENLPVGQKLLAALLVLLTTVLLVANLTFISAAYYISQESMAPQALQTIGRLVSNPSLVAEALQSPQSAERLLK
ELDSYSPLRAAALYDGKGERLAQLQHGDKLNLPERYRHIEAWQLTEFRSNQLITLPRPGTAPGHLLLVASSELPVAFYTG
TLTASLGILIFSVLLWLVIARQIKRLITRPIHQLEELSRQVTREENYALRASRGNHDEIGSLAEAFNTMLSRIEAREQQL
KRARDDSQAAYDQAQGLAEETRHTNRKLELEVQVRSKIEKKLTGFQNYLNSIIDSMPSALIALDEQLYVTQWNQEASALS
GTRLDEALNQPIFLAFEPLKPFLPQLKQTVEQHTVAKIERVTWFKDDEPKHYALTFYPLMGGAGRGVVIRIDDITQRLSL
EEMMVQSEKMLSVGGLAAGMAHEINNPLGAILHNVQNIRRRLSPDLPKNLEQAEQLGIELDTVNRYLQGREVPQLLDGIQ
QAGARAAKIVTHMLSFSRRSNRQMAPCDLPALIDQAVEIAGNDFDLAIGFDFKGQAIIRQFDPALGPVPGTANELEQVLL
NLLKNAAQAIHQREDDSEPGRITLRTRLNPPWAEIQVEDNGIGMSENVRKRTFEPFFTTKEIGQGTGLGLSVSYFIITNN
HKGQMEVQSAPGQGTCFTLRLPLAQPAPIAAETNQLPR
>Mature_677_residues
PLRQRLENLPVGQKLLAALLVLLTTVLLVANLTFISAAYYISQESMAPQALQTIGRLVSNPSLVAEALQSPQSAERLLKE
LDSYSPLRAAALYDGKGERLAQLQHGDKLNLPERYRHIEAWQLTEFRSNQLITLPRPGTAPGHLLLVASSELPVAFYTGT
LTASLGILIFSVLLWLVIARQIKRLITRPIHQLEELSRQVTREENYALRASRGNHDEIGSLAEAFNTMLSRIEAREQQLK
RARDDSQAAYDQAQGLAEETRHTNRKLELEVQVRSKIEKKLTGFQNYLNSIIDSMPSALIALDEQLYVTQWNQEASALSG
TRLDEALNQPIFLAFEPLKPFLPQLKQTVEQHTVAKIERVTWFKDDEPKHYALTFYPLMGGAGRGVVIRIDDITQRLSLE
EMMVQSEKMLSVGGLAAGMAHEINNPLGAILHNVQNIRRRLSPDLPKNLEQAEQLGIELDTVNRYLQGREVPQLLDGIQQ
AGARAAKIVTHMLSFSRRSNRQMAPCDLPALIDQAVEIAGNDFDLAIGFDFKGQAIIRQFDPALGPVPGTANELEQVLLN
LLKNAAQAIHQREDDSEPGRITLRTRLNPPWAEIQVEDNGIGMSENVRKRTFEPFFTTKEIGQGTGLGLSVSYFIITNNH
KGQMEVQSAPGQGTCFTLRLPLAQPAPIAAETNQLPR

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=378, Percent_Identity=32.010582010582, Blast_Score=153, Evalue=4e-38,
Organism=Escherichia coli, GI1790436, Length=267, Percent_Identity=29.9625468164794, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1790300, Length=400, Percent_Identity=25.25, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI145693157, Length=285, Percent_Identity=25.9649122807018, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI87081816, Length=130, Percent_Identity=33.8461538461538, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 75578; Mature: 75446

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLRQRLENLPVGQKLLAALLVLLTTVLLVANLTFISAAYYISQESMAPQALQTIGRLVS
CCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
NPSLVAEALQSPQSAERLLKELDSYSPLRAAALYDGKGERLAQLQHGDKLNLPERYRHIE
CHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHEECCCCHHHHHHHCCCCCCCHHHHHHHH
AWQLTEFRSNQLITLPRPGTAPGHLLLVASSELPVAFYTGTLTASLGILIFSVLLWLVIA
HHHHHHHCCCCEEECCCCCCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
RQIKRLITRPIHQLEELSRQVTREENYALRASRGNHDEIGSLAEAFNTMLSRIEAREQQL
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KRARDDSQAAYDQAQGLAEETRHTNRKLELEVQVRSKIEKKLTGFQNYLNSIIDSMPSAL
HHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IALDEQLYVTQWNQEASALSGTRLDEALNQPIFLAFEPLKPFLPQLKQTVEQHTVAKIER
HHHCCHHEEEECCCHHHHHCCCHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHH
VTWFKDDEPKHYALTFYPLMGGAGRGVVIRIDDITQRLSLEEMMVQSEKMLSVGGLAAGM
HHCCCCCCCCEEEEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHEINNPLGAILHNVQNIRRRLSPDLPKNLEQAEQLGIELDTVNRYLQGREVPQLLDGIQ
HHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHH
QAGARAAKIVTHMLSFSRRSNRQMAPCDLPALIDQAVEIAGNDFDLAIGFDFKGQAIIRQ
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHH
FDPALGPVPGTANELEQVLLNLLKNAAQAIHQREDDSEPGRITLRTRLNPPWAEIQVEDN
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEECCC
GIGMSENVRKRTFEPFFTTKEIGQGTGLGLSVSYFIITNNHKGQMEVQSAPGQGTCFTLR
CCCCCCCHHHHCCCCCCCHHHHCCCCCCCEEEEEEEEECCCCCCEEEECCCCCCCEEEEE
LPLAQPAPIAAETNQLPR
CCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PLRQRLENLPVGQKLLAALLVLLTTVLLVANLTFISAAYYISQESMAPQALQTIGRLVS
CHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
NPSLVAEALQSPQSAERLLKELDSYSPLRAAALYDGKGERLAQLQHGDKLNLPERYRHIE
CHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHEECCCCHHHHHHHCCCCCCCHHHHHHHH
AWQLTEFRSNQLITLPRPGTAPGHLLLVASSELPVAFYTGTLTASLGILIFSVLLWLVIA
HHHHHHHCCCCEEECCCCCCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
RQIKRLITRPIHQLEELSRQVTREENYALRASRGNHDEIGSLAEAFNTMLSRIEAREQQL
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KRARDDSQAAYDQAQGLAEETRHTNRKLELEVQVRSKIEKKLTGFQNYLNSIIDSMPSAL
HHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IALDEQLYVTQWNQEASALSGTRLDEALNQPIFLAFEPLKPFLPQLKQTVEQHTVAKIER
HHHCCHHEEEECCCHHHHHCCCHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHH
VTWFKDDEPKHYALTFYPLMGGAGRGVVIRIDDITQRLSLEEMMVQSEKMLSVGGLAAGM
HHCCCCCCCCEEEEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHEINNPLGAILHNVQNIRRRLSPDLPKNLEQAEQLGIELDTVNRYLQGREVPQLLDGIQ
HHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHH
QAGARAAKIVTHMLSFSRRSNRQMAPCDLPALIDQAVEIAGNDFDLAIGFDFKGQAIIRQ
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHH
FDPALGPVPGTANELEQVLLNLLKNAAQAIHQREDDSEPGRITLRTRLNPPWAEIQVEDN
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEECCC
GIGMSENVRKRTFEPFFTTKEIGQGTGLGLSVSYFIITNNHKGQMEVQSAPGQGTCFTLR
CCCCCCCHHHHCCCCCCCHHHHCCCCCCCEEEEEEEEECCCCCCEEEECCCCCCCEEEEE
LPLAQPAPIAAETNQLPR
CCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]