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The map label for this gene is ruvC [H]

Identifier: 77460630

GI number: 77460630

Start: 4968498

End: 4969025

Strand: Reverse

Name: ruvC [H]

Synonym: Pfl01_4409

Alternate gene names: 77460630

Gene position: 4969025-4968498 (Counterclockwise)

Preceding gene: 77460631

Following gene: 77460629

Centisome position: 77.18

GC content: 60.23

Gene sequence:

>528_bases
ATGACTTTAATTCTTGGTATCGACCCCGGTTCGCGCATTACCGGTTACGGCATTGTTCGCGATACCGGACGCGGCGGTTG
CATCTACGTCGCCTCGGGTTGTATCCGCACTGGTGCCGGCGAGCTGCATGAGCGGTTGCAGATTGTCTACCGCGGCGTGC
GGGAAATCATCCAGACCTACGGCCCGGTCACCATGGGCATCGAAAAGGTGTTCATGGCGAAAAACGCTGATTCGGCGCTC
AAGCTCGGGCAGGCCCGTGGGGCCGCTATCGTTGCCGGCGCCGAAGAAAGCCTGGAGATCGCCGAGTACACGGCCACTCA
GGTCAAGCAGGCTGTGGTGGGAACCGGTGCTGCCAATAAAGAGCAGGTGCAGATGATGGTCATGCACATGCTCAAGCTGA
CCAGCAAACCGCAAATCGACGCATCGGATGCCCTGGCGATTGCCATTTGTCACGCCCACACCCGCTCCAGTCTGTTGCCG
CATGGCTTGGGAACTGCACGCAGTCGTGGCGGGCGTCTGCGTCTCTGA

Upstream 100 bases:

>100_bases
GGCGTCGGCACATCAGCTAATGATGGTGCCTGACACACCGTCATCGCTGGCAAGCCAGCTCCCACATTTGTTTTTTGTGT
TTTTTCGAACCAGCAGGCTT

Downstream 100 bases:

>100_bases
TAGCATCAGCAGTCATTTTTACGGAATGTGGATTTCGTGCCTGGGTTGTCGGCCGTGAATCCATGCTCTGTCGGTCGCCA
GCCCACGGCTGGCCAACGCT

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC [H]

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MTLILGIDPGSRITGYGIVRDTGRGGCIYVASGCIRTGAGELHERLQIVYRGVREIIQTYGPVTMGIEKVFMAKNADSAL
KLGQARGAAIVAGAEESLEIAEYTATQVKQAVVGTGAANKEQVQMMVMHMLKLTSKPQIDASDALAIAICHAHTRSSLLP
HGLGTARSRGGRLRL

Sequences:

>Translated_175_residues
MTLILGIDPGSRITGYGIVRDTGRGGCIYVASGCIRTGAGELHERLQIVYRGVREIIQTYGPVTMGIEKVFMAKNADSAL
KLGQARGAAIVAGAEESLEIAEYTATQVKQAVVGTGAANKEQVQMMVMHMLKLTSKPQIDASDALAIAICHAHTRSSLLP
HGLGTARSRGGRLRL
>Mature_174_residues
TLILGIDPGSRITGYGIVRDTGRGGCIYVASGCIRTGAGELHERLQIVYRGVREIIQTYGPVTMGIEKVFMAKNADSALK
LGQARGAAIVAGAEESLEIAEYTATQVKQAVVGTGAANKEQVQMMVMHMLKLTSKPQIDASDALAIAICHAHTRSSLLPH
GLGTARSRGGRLRL

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family [H]

Homologues:

Organism=Escherichia coli, GI1788170, Length=174, Percent_Identity=55.7471264367816, Blast_Score=167, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176 [H]

Pfam domain/function: PF02075 RuvC [H]

EC number: =3.1.22.4 [H]

Molecular weight: Translated: 18531; Mature: 18400

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLILGIDPGSRITGYGIVRDTGRGGCIYVASGCIRTGAGELHERLQIVYRGVREIIQTY
CEEEEECCCCCCEEEEEEEEECCCCCEEEEECCCHHCCHHHHHHHHHHHHHHHHHHHHHC
GPVTMGIEKVFMAKNADSALKLGQARGAAIVAGAEESLEIAEYTATQVKQAVVGTGAANK
CCHHHHHHHHHHHCCCCHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCH
EQVQMMVMHMLKLTSKPQIDASDALAIAICHAHTRSSLLPHGLGTARSRGGRLRL
HHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHCCCCCCCCHHHCCCCCCCC
>Mature Secondary Structure 
TLILGIDPGSRITGYGIVRDTGRGGCIYVASGCIRTGAGELHERLQIVYRGVREIIQTY
EEEEECCCCCCEEEEEEEEECCCCCEEEEECCCHHCCHHHHHHHHHHHHHHHHHHHHHC
GPVTMGIEKVFMAKNADSALKLGQARGAAIVAGAEESLEIAEYTATQVKQAVVGTGAANK
CCHHHHHHHHHHHCCCCHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCH
EQVQMMVMHMLKLTSKPQIDASDALAIAICHAHTRSSLLPHGLGTARSRGGRLRL
HHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHCCCCCCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA