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The map label for this gene is ruvA [H]

Identifier: 77460629

GI number: 77460629

Start: 4967775

End: 4968383

Strand: Reverse

Name: ruvA [H]

Synonym: Pfl01_4408

Alternate gene names: 77460629

Gene position: 4968383-4967775 (Counterclockwise)

Preceding gene: 77460630

Following gene: 77460628

Centisome position: 77.17

GC content: 59.11

Gene sequence:

>609_bases
GTGATTGGACGCTTGCGCGGTACTCTGGCTGAGAAACAGCCGCCGCACCTGATTCTGGATGTAAACGGCCTCGGGTATGA
GCTGGAAGTGCCCATGACCACCCTTTATCGTCTGCCGTCGGTCGGTGAACCGCTGACCTTGCACACCCATTTGGTCGTAC
GCGAAGACGCACAGTTACTCTATGGTTTTGCCGGCAAGCGTGAGCGAGACTTTTTTCGCGAGTTGATCCGTCTCAACGGT
GTAGGGCCGAAACTGGCCCTGGCCTTGATGTCGAGTCTGGAAGTCGACGAACTGATCCGCTGCGTACAGTCCCAGGACAC
CTCGGCGCTGACTAAGGTGCCGGGCGTGGGCAAGAAAACCGCCGAGCGTCTGCTGGTCGAGCTCAAGAATCGCTTCAAGG
CCTGGGAAACGTCGCCGGCCATGTTCGCGCTGGTGCCGAACCAGCCGGACGGCCCGGCGCCAGTCAATACGGCCGAGAAC
GATGCGGTCAGCGCGCTGATTTCCCTGGGCTACAAGCCACAGGAAGCGAGCAAGGCGATTTCCGCGATCAAAGAGAAAGG
CCTGAGCAGCGAAGACATGATTCGACGCGCCCTGAAGGGAATGATTTAA

Upstream 100 bases:

>100_bases
ATTTTTACGGAATGTGGATTTCGTGCCTGGGTTGTCGGCCGTGAATCCATGCTCTGTCGGTCGCCAGCCCACGGCTGGCC
AACGCTCAAGGATCTGAAAC

Downstream 100 bases:

>100_bases
GTGATTGAAGCTGATCGTCTGATCGCCGCCACGCACAGTCCGCGTGAGCGCGAAGAAGTCCAGGATCGGGCGATACGTCC
CGTCAGCCTGGCCGAGTACA

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MIGRLRGTLAEKQPPHLILDVNGLGYELEVPMTTLYRLPSVGEPLTLHTHLVVREDAQLLYGFAGKRERDFFRELIRLNG
VGPKLALALMSSLEVDELIRCVQSQDTSALTKVPGVGKKTAERLLVELKNRFKAWETSPAMFALVPNQPDGPAPVNTAEN
DAVSALISLGYKPQEASKAISAIKEKGLSSEDMIRRALKGMI

Sequences:

>Translated_202_residues
MIGRLRGTLAEKQPPHLILDVNGLGYELEVPMTTLYRLPSVGEPLTLHTHLVVREDAQLLYGFAGKRERDFFRELIRLNG
VGPKLALALMSSLEVDELIRCVQSQDTSALTKVPGVGKKTAERLLVELKNRFKAWETSPAMFALVPNQPDGPAPVNTAEN
DAVSALISLGYKPQEASKAISAIKEKGLSSEDMIRRALKGMI
>Mature_202_residues
MIGRLRGTLAEKQPPHLILDVNGLGYELEVPMTTLYRLPSVGEPLTLHTHLVVREDAQLLYGFAGKRERDFFRELIRLNG
VGPKLALALMSSLEVDELIRCVQSQDTSALTKVPGVGKKTAERLLVELKNRFKAWETSPAMFALVPNQPDGPAPVNTAEN
DAVSALISLGYKPQEASKAISAIKEKGLSSEDMIRRALKGMI

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=205, Percent_Identity=52.1951219512195, Blast_Score=215, Evalue=2e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 22173; Mature: 22173

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGRLRGTLAEKQPPHLILDVNGLGYELEVPMTTLYRLPSVGEPLTLHTHLVVREDAQLL
CCCCHHCHHHCCCCCEEEEEECCCCEEEECCHHHHHHCCCCCCCEEEEEEEEEECCHHHH
YGFAGKRERDFFRELIRLNGVGPKLALALMSSLEVDELIRCVQSQDTSALTKVPGVGKKT
HHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHCCCCCHHH
AERLLVELKNRFKAWETSPAMFALVPNQPDGPAPVNTAENDAVSALISLGYKPQEASKAI
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHH
SAIKEKGLSSEDMIRRALKGMI
HHHHHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MIGRLRGTLAEKQPPHLILDVNGLGYELEVPMTTLYRLPSVGEPLTLHTHLVVREDAQLL
CCCCHHCHHHCCCCCEEEEEECCCCEEEECCHHHHHHCCCCCCCEEEEEEEEEECCHHHH
YGFAGKRERDFFRELIRLNGVGPKLALALMSSLEVDELIRCVQSQDTSALTKVPGVGKKT
HHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHCCCCCHHH
AERLLVELKNRFKAWETSPAMFALVPNQPDGPAPVNTAENDAVSALISLGYKPQEASKAI
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHH
SAIKEKGLSSEDMIRRALKGMI
HHHHHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA