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The map label for this gene is tolQ [H]

Identifier: 77460626

GI number: 77460626

Start: 4965433

End: 4966098

Strand: Reverse

Name: tolQ [H]

Synonym: Pfl01_4405

Alternate gene names: 77460626

Gene position: 4966098-4965433 (Counterclockwise)

Preceding gene: 77460627

Following gene: 77460625

Centisome position: 77.13

GC content: 61.11

Gene sequence:

>666_bases
ATGTGGAGCCTGGTCAGCAATGCCAGCATCGTGGTGCAGTTGGTAATGTTGACTCTGGTGGCCGCATCGGTGACCTCATG
GATCATGATCTTTCAGCGCAGCAATCTGATACGCGCCGGTCGACGTGCCCTCGAGAGCTTCGAGGAGCGATTCTGGTCGG
GTATCGACCTGTCCAAACTCTACCGTCAGGCTGGCAGCAATCCGGATCCGGATTCCGGCGTCGAGCAGATCTTCCGTGCC
GGCTTCAAGGAGTTCTCCCGTCTGCGTCAGCAGCCAGGCGTCGATCCTGAAGCGGTGATGGAAGGCGTGGCCCGTGCCAT
GCGCGTCGCCATCTCCCGTGAGGAAGAGAAACTCGAGCAGAGCCTGCCGTTCCTCGCCACCGTAGGTTCCGTCAGCCCGT
ACATCGGTCTGTTCGGTACCGTCTGGGGGATCATGAACTCCTTCCGTGGTCTGGCCAGCGCCCAGCAGGCCACTCTGGCC
ACCGTCGCACCCGGCATCGCCGAAGCCCTGATCGCCACCGCGATCGGTCTGTTCGCCGCGATCCCGGCCGTTATTGCTTA
CAACCGTTTCTCTGCCCGCAGCGAAACCTTGCTGAGCCGCTACTACACCTTCGCCGATGAGTTCCAGGCGATCCTGCACC
GCAAAGTGCACACCAGCGAAGAATAA

Upstream 100 bases:

>100_bases
CCCGAAGACCTGCGTGCGGCCTTTGCCGACGCGGTCGGCACGGGTACACACTCAAAGCAGGAGATAAAGCGTGGAAGCTA
ACGTCGTCGACCATTCCTCC

Downstream 100 bases:

>100_bases
GCAGGTATTTCCCGATGGCTTTAATCACTCGAGCCCGACACAAGCGCAAGCCGGTCGCCGAGATGAACGTAGTGCCTTAC
ATCGACGTGATGCTGGTGCT

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MWSLVSNASIVVQLVMLTLVAASVTSWIMIFQRSNLIRAGRRALESFEERFWSGIDLSKLYRQAGSNPDPDSGVEQIFRA
GFKEFSRLRQQPGVDPEAVMEGVARAMRVAISREEEKLEQSLPFLATVGSVSPYIGLFGTVWGIMNSFRGLASAQQATLA
TVAPGIAEALIATAIGLFAAIPAVIAYNRFSARSETLLSRYYTFADEFQAILHRKVHTSEE

Sequences:

>Translated_221_residues
MWSLVSNASIVVQLVMLTLVAASVTSWIMIFQRSNLIRAGRRALESFEERFWSGIDLSKLYRQAGSNPDPDSGVEQIFRA
GFKEFSRLRQQPGVDPEAVMEGVARAMRVAISREEEKLEQSLPFLATVGSVSPYIGLFGTVWGIMNSFRGLASAQQATLA
TVAPGIAEALIATAIGLFAAIPAVIAYNRFSARSETLLSRYYTFADEFQAILHRKVHTSEE
>Mature_221_residues
MWSLVSNASIVVQLVMLTLVAASVTSWIMIFQRSNLIRAGRRALESFEERFWSGIDLSKLYRQAGSNPDPDSGVEQIFRA
GFKEFSRLRQQPGVDPEAVMEGVARAMRVAISREEEKLEQSLPFLATVGSVSPYIGLFGTVWGIMNSFRGLASAQQATLA
TVAPGIAEALIATAIGLFAAIPAVIAYNRFSARSETLLSRYYTFADEFQAILHRKVHTSEE

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=219, Percent_Identity=56.1643835616438, Blast_Score=240, Evalue=6e-65,
Organism=Escherichia coli, GI1789381, Length=193, Percent_Identity=37.8238341968912, Blast_Score=120, Evalue=8e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014163 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 24353; Mature: 24353

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWSLVSNASIVVQLVMLTLVAASVTSWIMIFQRSNLIRAGRRALESFEERFWSGIDLSKL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
YRQAGSNPDPDSGVEQIFRAGFKEFSRLRQQPGVDPEAVMEGVARAMRVAISREEEKLEQ
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SLPFLATVGSVSPYIGLFGTVWGIMNSFRGLASAQQATLATVAPGIAEALIATAIGLFAA
HCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPAVIAYNRFSARSETLLSRYYTFADEFQAILHRKVHTSEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MWSLVSNASIVVQLVMLTLVAASVTSWIMIFQRSNLIRAGRRALESFEERFWSGIDLSKL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
YRQAGSNPDPDSGVEQIFRAGFKEFSRLRQQPGVDPEAVMEGVARAMRVAISREEEKLEQ
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SLPFLATVGSVSPYIGLFGTVWGIMNSFRGLASAQQATLATVAPGIAEALIATAIGLFAA
HCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPAVIAYNRFSARSETLLSRYYTFADEFQAILHRKVHTSEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8955385; 10984043 [H]