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The map label for this gene is pgl [H]

Identifier: 77460583

GI number: 77460583

Start: 4914270

End: 4914968

Strand: Reverse

Name: pgl [H]

Synonym: Pfl01_4362

Alternate gene names: 77460583

Gene position: 4914968-4914270 (Counterclockwise)

Preceding gene: 77460584

Following gene: 77460582

Centisome position: 76.34

GC content: 64.81

Gene sequence:

>699_bases
GTGAAACTGCCCGAGGGCGTGAATGCCCATGAATTCAAGAGCCCGGTGCTGCTCGCCGAAGGCCTGGCGCTGAATGTCGC
CAAGCAATTGAGCGAAGCGTTGGCGGCACGCGGCAACGCCGTGCTGGTGGTGTCCGGCGGCCGTAGTCCGGTGGCGTTTT
TCCAGCATCTGGCCAAGCAGGAACTGGACTGGTCGAAGGTCGTCGTGACCCTGGCCGACGAACGCTGGGTGCCGGTCGAA
CACGCCGACAGCAACGCCGGTCTGCTCAAGCAGTATCTGCTCAAGGGCCCGGCGGCCAAGGCGCAGTTCCTCAGCCTCTA
CAGCGCGGCGGCCAACGTCGAGCAGGCTGCGGAGCAGGCCGATCGTTTGCTCGCCGAGTTGCCGCCCATCGACGTGCTGG
TGCTGGGCATGGGCGATGACGGTCACACCGCCTCGCTGTTCCCGGACAGCCCGAACCTGGTCGAAGCCCTGCAAGCCGAC
GGCACCCGTCGCTGCTGGCCAATGCTCGCGCCGAGTGTGCCGCGTCAGCGCCTGACCATGAGCCGTGCACTGCTGGCGTC
GGCGAGGCACAAGATTCTGTCGATTTCCGGTCAGTCGAAACTGACCACCCTGAATGCCGCACTGGCATCCAACGACGTCG
CCGCCATGCCGGTTCGCGCGTTTCTGCAACCTACGTTAGAGATTTACTGGTGCCCATGA

Upstream 100 bases:

>100_bases
GGTGACGCGCCCAAGCCGTATGCGGCCGGGTCGTGGGGGCCGATGAGCTCCATTGCATTGATCACGCGGGACGGGAGGTC
GTGGTATGGCGATATCTGAT

Downstream 100 bases:

>100_bases
GCCAAGGAACAGCCGCTATGACAACCCCATCCCCGACCGTTTCCATGGCGGACAAAGTTGCCCTGATCGACAGCCTCTGC
GCCAAGGCGCGGATCCTGCC

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MKLPEGVNAHEFKSPVLLAEGLALNVAKQLSEALAARGNAVLVVSGGRSPVAFFQHLAKQELDWSKVVVTLADERWVPVE
HADSNAGLLKQYLLKGPAAKAQFLSLYSAAANVEQAAEQADRLLAELPPIDVLVLGMGDDGHTASLFPDSPNLVEALQAD
GTRRCWPMLAPSVPRQRLTMSRALLASARHKILSISGQSKLTTLNAALASNDVAAMPVRAFLQPTLEIYWCP

Sequences:

>Translated_232_residues
MKLPEGVNAHEFKSPVLLAEGLALNVAKQLSEALAARGNAVLVVSGGRSPVAFFQHLAKQELDWSKVVVTLADERWVPVE
HADSNAGLLKQYLLKGPAAKAQFLSLYSAAANVEQAAEQADRLLAELPPIDVLVLGMGDDGHTASLFPDSPNLVEALQAD
GTRRCWPMLAPSVPRQRLTMSRALLASARHKILSISGQSKLTTLNAALASNDVAAMPVRAFLQPTLEIYWCP
>Mature_232_residues
MKLPEGVNAHEFKSPVLLAEGLALNVAKQLSEALAARGNAVLVVSGGRSPVAFFQHLAKQELDWSKVVVTLADERWVPVE
HADSNAGLLKQYLLKGPAAKAQFLSLYSAAANVEQAAEQADRLLAELPPIDVLVLGMGDDGHTASLFPDSPNLVEALQAD
GTRRCWPMLAPSVPRQRLTMSRALLASARHKILSISGQSKLTTLNAALASNDVAAMPVRAFLQPTLEIYWCP

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI6912586, Length=238, Percent_Identity=31.5126050420168, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI52145310, Length=228, Percent_Identity=29.3859649122807, Blast_Score=79, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6321957, Length=205, Percent_Identity=29.2682926829268, Blast_Score=76, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6321687, Length=218, Percent_Identity=29.3577981651376, Blast_Score=75, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24641119, Length=184, Percent_Identity=27.7173913043478, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 24891; Mature: 24891

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLPEGVNAHEFKSPVLLAEGLALNVAKQLSEALAARGNAVLVVSGGRSPVAFFQHLAKQ
CCCCCCCCHHHHCCCCHHHCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHH
ELDWSKVVVTLADERWVPVEHADSNAGLLKQYLLKGPAAKAQFLSLYSAAANVEQAAEQA
CCCHHHEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
DRLLAELPPIDVLVLGMGDDGHTASLFPDSPNLVEALQADGTRRCWPMLAPSVPRQRLTM
HHHHHHCCCCEEEEEEECCCCCEEEECCCCCHHHHHHHCCCCCCHHHCCCCCCCHHHHHH
SRALLASARHKILSISGQSKLTTLNAALASNDVAAMPVRAFLQPTLEIYWCP
HHHHHHHHHHHEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEECC
>Mature Secondary Structure
MKLPEGVNAHEFKSPVLLAEGLALNVAKQLSEALAARGNAVLVVSGGRSPVAFFQHLAKQ
CCCCCCCCHHHHCCCCHHHCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHH
ELDWSKVVVTLADERWVPVEHADSNAGLLKQYLLKGPAAKAQFLSLYSAAANVEQAAEQA
CCCHHHEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
DRLLAELPPIDVLVLGMGDDGHTASLFPDSPNLVEALQADGTRRCWPMLAPSVPRQRLTM
HHHHHHCCCCEEEEEEECCCCCEEEECCCCCHHHHHHHCCCCCCHHHCCCCCCCHHHHHH
SRALLASARHKILSISGQSKLTTLNAALASNDVAAMPVRAFLQPTLEIYWCP
HHHHHHHHHHHEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA