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The map label for this gene is eda [H]

Identifier: 77460582

GI number: 77460582

Start: 4913587

End: 4914252

Strand: Reverse

Name: eda [H]

Synonym: Pfl01_4361

Alternate gene names: 77460582

Gene position: 4914252-4913587 (Counterclockwise)

Preceding gene: 77460583

Following gene: 77460581

Centisome position: 76.33

GC content: 65.62

Gene sequence:

>666_bases
ATGACAACCCCATCCCCGACCGTTTCCATGGCGGACAAAGTTGCCCTGATCGACAGCCTCTGCGCCAAGGCGCGGATCCT
GCCGGTGATCACCATCGCCCGCGAACAGGACGTGCTGCCGCTGGCCGACGCCCTGGCCGCCGGTGGTCTGACCGCGCTGG
AAGTGACCCTGCGTTCGCAGTTCGGCCTCAAGGCGATCCAGATCCTGCGCGAACAGCGCCCGGAGCTGGTGACCGGTGCC
GGCACCGTGCTCGACCGCAATATGCTGGCCGCGGCCGAAGCCGCCGGTTCGCAGTTCATCGTCACCCCGGGCATCACCCG
TGACCTGCTGGAAGCCAGCGTCGAGAGCCCGATCCCGCTGCTGCCGGGCATCAGCAATGCCTCCGGCATCATGGAAGGCT
ATGGCCTGGGGTATCGCCGCTTCAAGCTGTTCCCGGCTGAAGTCAGCGGCGGCGTGGCGGCAATCAAGGCCCTCGGCGGC
CCGTTCGGCGAAGTGAAATTCTGCCCGACTGGCGGCGTCGGCCCTGCCAACATCAAGAGCTATATGGCGCTGAAAAACGT
CATGTGCGTGGGCGGTAGCTGGATGCTCGATCCTGAGTGGATCAAGAACGGCGACTGGGCCCGCATTCAGGAATGCACTG
CCGAGGCTCTGGCGCTGCTGGACTGA

Upstream 100 bases:

>100_bases
CCGCACTGGCATCCAACGACGTCGCCGCCATGCCGGTTCGCGCGTTTCTGCAACCTACGTTAGAGATTTACTGGTGCCCA
TGAGCCAAGGAACAGCCGCT

Downstream 100 bases:

>100_bases
TCTTCAACTGACACTTCGTTGTGTGTTCTACGGCTTTACGGTGCGCTTGGTCGGTGCACCGTTTTTTTTTGCCCGAAAAC
CTTCGTTATCTCGAGATACA

Product: keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase

Products: NA

Alternate protein names: KDPG-aldolase; Phospho-2-dehydro-3-deoxygluconate aldolase; Phospho-2-keto-3-deoxygluconate aldolase [H]

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MTTPSPTVSMADKVALIDSLCAKARILPVITIAREQDVLPLADALAAGGLTALEVTLRSQFGLKAIQILREQRPELVTGA
GTVLDRNMLAAAEAAGSQFIVTPGITRDLLEASVESPIPLLPGISNASGIMEGYGLGYRRFKLFPAEVSGGVAAIKALGG
PFGEVKFCPTGGVGPANIKSYMALKNVMCVGGSWMLDPEWIKNGDWARIQECTAEALALLD

Sequences:

>Translated_221_residues
MTTPSPTVSMADKVALIDSLCAKARILPVITIAREQDVLPLADALAAGGLTALEVTLRSQFGLKAIQILREQRPELVTGA
GTVLDRNMLAAAEAAGSQFIVTPGITRDLLEASVESPIPLLPGISNASGIMEGYGLGYRRFKLFPAEVSGGVAAIKALGG
PFGEVKFCPTGGVGPANIKSYMALKNVMCVGGSWMLDPEWIKNGDWARIQECTAEALALLD
>Mature_220_residues
TTPSPTVSMADKVALIDSLCAKARILPVITIAREQDVLPLADALAAGGLTALEVTLRSQFGLKAIQILREQRPELVTGAG
TVLDRNMLAAAEAAGSQFIVTPGITRDLLEASVESPIPLLPGISNASGIMEGYGLGYRRFKLFPAEVSGGVAAIKALGGP
FGEVKFCPTGGVGPANIKSYMALKNVMCVGGSWMLDPEWIKNGDWARIQECTAEALALLD

Specific function: KEY ENZYME IN THE ENTNER-DOUDOROFF PATHWAY. PARTICIPATES IN THE REGULATION OF THE INTRACELLULAR LEVEL OF GLYOXYLATE. [C]

COG id: COG0800

COG function: function code G; 2-keto-3-deoxy-6-phosphogluconate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KHG/KDPG aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1788156, Length=182, Percent_Identity=47.8021978021978, Blast_Score=189, Evalue=1e-49,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000887
- InterPro:   IPR013785 [H]

Pfam domain/function: PF01081 Aldolase [H]

EC number: =4.1.2.14 [H]

Molecular weight: Translated: 23167; Mature: 23036

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00159 ALDOLASE_KDPG_KHG_1 ; PS00160 ALDOLASE_KDPG_KHG_2 ; PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPSPTVSMADKVALIDSLCAKARILPVITIAREQDVLPLADALAAGGLTALEVTLRSQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHCCCCEEEEEHHHH
FGLKAIQILREQRPELVTGAGTVLDRNMLAAAEAAGSQFIVTPGITRDLLEASVESPIPL
CCHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCCCC
LPGISNASGIMEGYGLGYRRFKLFPAEVSGGVAAIKALGGPFGEVKFCPTGGVGPANIKS
CCCCCCCHHHHHHCCCCEEEEEEECHHHCCHHHHHHHHCCCCCCEEECCCCCCCHHHHHH
YMALKNVMCVGGSWMLDPEWIKNGDWARIQECTAEALALLD
HHHHHHHHEECCCEEECHHHHCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTPSPTVSMADKVALIDSLCAKARILPVITIAREQDVLPLADALAAGGLTALEVTLRSQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHCCCCEEEEEHHHH
FGLKAIQILREQRPELVTGAGTVLDRNMLAAAEAAGSQFIVTPGITRDLLEASVESPIPL
CCHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCCCC
LPGISNASGIMEGYGLGYRRFKLFPAEVSGGVAAIKALGGPFGEVKFCPTGGVGPANIKS
CCCCCCCHHHHHHCCCCEEEEEEECHHHCCHHHHHHHHCCCCCCEEECCCCCCCHHHHHH
YMALKNVMCVGGSWMLDPEWIKNGDWARIQECTAEALALLD
HHHHHHHHEECCCEEECHHHHCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6988426; 7161801; 974067 [H]