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The map label for this gene is bdlA [H]

Identifier: 77460564

GI number: 77460564

Start: 4896490

End: 4897809

Strand: Reverse

Name: bdlA [H]

Synonym: Pfl01_4343

Alternate gene names: 77460564

Gene position: 4897809-4896490 (Counterclockwise)

Preceding gene: 77460565

Following gene: 77460559

Centisome position: 76.07

GC content: 58.86

Gene sequence:

>1320_bases
ATGTTCAACCTACATCACAAGGCTGATCTGCAGGAAATCGAACGTTTCAGCTGTGCCCTGACCGAAGCCAACGCCAAGCT
GGCGGCGATCAGCCGTTCGATGGCAATGATCGAATTCACCCCCGAGGGCATCGTGCTGGATGCCAATGACAACTTCTGCA
AGACCATGGGCTACAGCGCCGATGAAGTGCGTGGCAAACATCACCGGATCTTTTGTGAAGAAGCGTTTTATCGCAGCGAG
GAATACGCCAAGTTGTGGCGTGACCTGGCCCGGGGCGAACCCATCAGCGGCACTTTCCTGCGCTTGAACAAAAGCGGTCG
GGAGATCTGGCTCGAAGCCAGTTACATGCCGGTGTATGGCCCGGACAAACAGGTCCGGAGTGTGATCAAAGTGGCGGCGG
ACATCACCGCGCGAGTGAACAAGGAAAAAGAAGAAGAAAGCATGCTGGCCGCCATCGGCCGTTCGATGGCGGTGATCGAG
TTCACCCCGGAAGGCAATGTGATCACGGCCAACGACAACTTCCTCAAGACCATGCAGTACTCGCTCAACGAAATCGTCGG
CCATCATCACAGTCTGTTCTGTCACCGGGTCGAGGCCGAGTCCGCGCAGTACAAGGCGTTCTGGGCCTCGCTCAATCGCG
GCGAATATCACTCGCACCGCTTCGAACGCAAGAACAAGTCGGGGCAGACCGTTTACCTCGAAGCCTCGTATAACCCGTTG
TTCGATGCCAAAGGCCGGTTGTACAAAGTGGTGAAGTTCGCCAGTGACATCACCCACCAGATGACCACCTTGCAGACCGC
TGCGGAATCGGCCCACAGCACCTCTGTACAAAACGACGCCTGCGCGCAAAAAGGCTCACAGGTCGTGCAGCAAACGGTGC
AGATCATTCAGGACATTTCCCGCGACCTCAACGAAGCGGCGCTGAGCATCGATGCGGTCAGCAAGCAGTCGGACATCATC
GGCACCATCGTCCAGACCATTCGCGGGATTGCCGACCAGACCAACCTGCTGGCGCTCAACGCGGCGATCGAAGCGGCAAG
GGCGGGTGAGCACGGGCGTGGTTTTGCGGTGGTGGCGGACGAGGTGCGCAGCCTCGCGGCGCGAACCAGCCAGGCGACCG
TGGAGATCGTCGACGTGGTGCGCAAGAACCATGAGCTGTCACTGAGCGCAGTGTCGAGCATGCAGTCGAGCCTGAGCCGC
ACCGGGCTCGGGGTGGAACTGGCGAACGAGGCGGGGGATGCGATTCGGGAGATTCAGCAGGGCTCGCGGCATGTGGTGGA
TGCGATCAGTCAGTTCAATGAGACGTTGAGATTAGAGTAG

Upstream 100 bases:

>100_bases
GTGGAGGAAGGCGTGTGCCTGTTCTGTGGAACGTAGTGGTGGATTCTGAAAGACCTGAACTTTCATCAAATCAAAAGAAC
GCGCGGAAGGTGATCGAGAC

Downstream 100 bases:

>100_bases
CGACTTGGGAATTGCCCCTCTGTATAGAGGGGCAAAATTTTCTCGATCACTCTTTTTCGGTCAAGGAAAAGCTACCAGTG
GCATTTGCATAATTGGACGG

Product: Pas/Pac sensor-containing chemotaxis sensory transducer

Products: NA

Alternate protein names: Chemotaxis regulator BdlA [H]

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MFNLHHKADLQEIERFSCALTEANAKLAAISRSMAMIEFTPEGIVLDANDNFCKTMGYSADEVRGKHHRIFCEEAFYRSE
EYAKLWRDLARGEPISGTFLRLNKSGREIWLEASYMPVYGPDKQVRSVIKVAADITARVNKEKEEESMLAAIGRSMAVIE
FTPEGNVITANDNFLKTMQYSLNEIVGHHHSLFCHRVEAESAQYKAFWASLNRGEYHSHRFERKNKSGQTVYLEASYNPL
FDAKGRLYKVVKFASDITHQMTTLQTAAESAHSTSVQNDACAQKGSQVVQQTVQIIQDISRDLNEAALSIDAVSKQSDII
GTIVQTIRGIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRSLAARTSQATVEIVDVVRKNHELSLSAVSSMQSSLSR
TGLGVELANEAGDAIREIQQGSRHVVDAISQFNETLRLE

Sequences:

>Translated_439_residues
MFNLHHKADLQEIERFSCALTEANAKLAAISRSMAMIEFTPEGIVLDANDNFCKTMGYSADEVRGKHHRIFCEEAFYRSE
EYAKLWRDLARGEPISGTFLRLNKSGREIWLEASYMPVYGPDKQVRSVIKVAADITARVNKEKEEESMLAAIGRSMAVIE
FTPEGNVITANDNFLKTMQYSLNEIVGHHHSLFCHRVEAESAQYKAFWASLNRGEYHSHRFERKNKSGQTVYLEASYNPL
FDAKGRLYKVVKFASDITHQMTTLQTAAESAHSTSVQNDACAQKGSQVVQQTVQIIQDISRDLNEAALSIDAVSKQSDII
GTIVQTIRGIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRSLAARTSQATVEIVDVVRKNHELSLSAVSSMQSSLSR
TGLGVELANEAGDAIREIQQGSRHVVDAISQFNETLRLE
>Mature_439_residues
MFNLHHKADLQEIERFSCALTEANAKLAAISRSMAMIEFTPEGIVLDANDNFCKTMGYSADEVRGKHHRIFCEEAFYRSE
EYAKLWRDLARGEPISGTFLRLNKSGREIWLEASYMPVYGPDKQVRSVIKVAADITARVNKEKEEESMLAAIGRSMAVIE
FTPEGNVITANDNFLKTMQYSLNEIVGHHHSLFCHRVEAESAQYKAFWASLNRGEYHSHRFERKNKSGQTVYLEASYNPL
FDAKGRLYKVVKFASDITHQMTTLQTAAESAHSTSVQNDACAQKGSQVVQQTVQIIQDISRDLNEAALSIDAVSKQSDII
GTIVQTIRGIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRSLAARTSQATVEIVDVVRKNHELSLSAVSSMQSSLSR
TGLGVELANEAGDAIREIQQGSRHVVDAISQFNETLRLE

Specific function: Essential for biofilm dispersion by sensing environmental cues. May be involved in sensing and transducing signals within cells, resulting in the modulation of c-di-GMP levels, swimming motility and adhesiveness of the bacterial cell surface [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=178, Percent_Identity=37.6404494382022, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1788194, Length=179, Percent_Identity=37.9888268156425, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1788195, Length=170, Percent_Identity=37.0588235294118, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1787690, Length=124, Percent_Identity=44.3548387096774, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1789453, Length=68, Percent_Identity=57.3529411764706, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00015 MCPsignal; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 48715; Mature: 48715

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS50113 PAC ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNLHHKADLQEIERFSCALTEANAKLAAISRSMAMIEFTPEGIVLDANDNFCKTMGYSA
CCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCEEEEEECCCCEEEECCCCHHHHCCCCH
DEVRGKHHRIFCEEAFYRSEEYAKLWRDLARGEPISGTFLRLNKSGREIWLEASYMPVYG
HHHCCCHHEEEEHHHHHCCHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCCCC
PDKQVRSVIKVAADITARVNKEKEEESMLAAIGRSMAVIEFTPEGNVITANDNFLKTMQY
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCEEECCCCHHHHHHH
SLNEIVGHHHSLFCHRVEAESAQYKAFWASLNRGEYHSHRFERKNKSGQTVYLEASYNPL
HHHHHHCCHHHHHEEEECCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEEEECCCCC
FDAKGRLYKVVKFASDITHQMTTLQTAAESAHSTSVQNDACAQKGSQVVQQTVQIIQDIS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RDLNEAALSIDAVSKQSDIIGTIVQTIRGIADQTNLLALNAAIEAARAGEHGRGFAVVAD
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCCCCEEEHHH
EVRSLAARTSQATVEIVDVVRKNHELSLSAVSSMQSSLSRTGLGVELANEAGDAIREIQQ
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHH
GSRHVVDAISQFNETLRLE
CCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFNLHHKADLQEIERFSCALTEANAKLAAISRSMAMIEFTPEGIVLDANDNFCKTMGYSA
CCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCEEEEEECCCCEEEECCCCHHHHCCCCH
DEVRGKHHRIFCEEAFYRSEEYAKLWRDLARGEPISGTFLRLNKSGREIWLEASYMPVYG
HHHCCCHHEEEEHHHHHCCHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCCCC
PDKQVRSVIKVAADITARVNKEKEEESMLAAIGRSMAVIEFTPEGNVITANDNFLKTMQY
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCEEECCCCHHHHHHH
SLNEIVGHHHSLFCHRVEAESAQYKAFWASLNRGEYHSHRFERKNKSGQTVYLEASYNPL
HHHHHHCCHHHHHEEEECCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEEEECCCCC
FDAKGRLYKVVKFASDITHQMTTLQTAAESAHSTSVQNDACAQKGSQVVQQTVQIIQDIS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RDLNEAALSIDAVSKQSDIIGTIVQTIRGIADQTNLLALNAAIEAARAGEHGRGFAVVAD
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCCCCEEEHHH
EVRSLAARTSQATVEIVDVVRKNHELSLSAVSSMQSSLSRTGLGVELANEAGDAIREIQQ
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHH
GSRHVVDAISQFNETLRLE
CCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]