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The map label for this gene is yyaJ [H]

Identifier: 77460561

GI number: 77460561

Start: 4893674

End: 4895107

Strand: Direct

Name: yyaJ [H]

Synonym: Pfl01_4340

Alternate gene names: 77460561

Gene position: 4893674-4895107 (Clockwise)

Preceding gene: 77460560

Following gene: 77460562

Centisome position: 76.01

GC content: 62.41

Gene sequence:

>1434_bases
ATGGATCAGCCCATGACTGCACACGCCCCCGCCGCGCAACGCGACGGCATCGACCCCATACGCGCCGCACAGATTTCCGC
CCGCATCGACCGCCTCCCGGCAGTCGCCACGATCTGGCGGCTGGTGGCGCTGCTGTCGATCGGTGGTTTCTTCGAACTCT
ACGATCTGTTCCAGACCGCCTATATCAGCCCCGGCCTGATCCGCGATGGCATCTTCGCCATCGGCAATCAGGGCGTGTTC
GGTTTCTCCGATCAGGCCGCGTTCGCCTCGGCGACGTTCCTCGGACTGTTTCTCGGCGCCAGTCTGCTGAGCCCGATGGC
GGATCGCTTCGGGCGGCGGGCGATCTTCACTTTCGCGCTGGTCTGGTACACCGTCGCCACAGTTTTAATGGGCGTACAGA
GTTCAGCGCTGGGGATCATCTGCATGCGTTTTCTGGTGGGTATCGGCCTCGGCATCGAACTGGTGACCATCGACGCCTAC
CTCTCGGAACTGGTGCCCAAGCGCATGCGCAGTTCGGCGTTTGCCTTCGCGTTTTTCGTGCAGTTCCTGTCGGTGCCGGC
GGTGGCGCTGATGTCCTGGTGGCTGGTGCCGCAGGCGCCGTTCGGCATCAGTGGCTGGCGTTGGGTGGTGTTGGCGAGCG
CGGTGTTTGCGCTGTTCATCTGGTGGCTGCGCAAACGTCTGCCGGAGTCGCCGCGCTGGCTGGCGCAGCATGGCCGCTTC
GATGAGGCGAACCGGATTCTCGACGGCATCGAGGCGCGTTGTGAGAAGGATCACCGTCAGCCACTGGATGCGCCGGAAGC
AGTAGCCGTCGATGTCGAGGGCAAGGGCCGTTTCGCCGATATCTGGCAGCCACCGTACCGGCGCCGCGCGCTGATGCTGA
TTGTCTTCCACATCTTCCAGGCGATCGGTTTCTTCGGCTTCGGCAACTGGCTGCCAGCGCTGCTTTCCGGTCAGGGTGTC
AGCGTCACCCACAGTCTGATGTACGCGTTCATCATCACCCTCGCCTACCCGCTCGGGCCGTTGCTGTTCGTCAAATTCGC
CAACCGCTTCGAGAACAAGTGGCAGATCGTCGGCTCGGCCCTCGGCGCCATGACTTTCGGCACCCTGTTCGCGTTGCAGA
CCAGCGCCGTCGGCCTGATCTTCTGCGGTGTGATGATCACCTTCTGCAACGCCTGGCTGAGCTTCAGTTACCACTCCTAT
CAGAGCGAACTGTTCCCCACCAACATCCGCGCTCGGGCCGTCGGGTTCTGCTATTCGTTCAGTCGTTTGTCGACGGTGTT
CAGCAGCCTGTTGATCGGTCTGTTCCTCGACCACTTCGGGACACCGGGCGTGTTGGCGTTCATCGTCGCCAGCATGTTGA
TCGTGATGCTGACCATCGGCTGTTTCGGTCCTCGCACCCGAAACCTGGCGCTGGAAAACATCGCCCATCGCTGA

Upstream 100 bases:

>100_bases
AAGCGGATATTGCAAGAAATCGTCGGTTTTACCTCGCCAACTGCCGATATAAACAATCCTTGATTTCCGATAGCAGGCTA
AGCTTTTCCATCAATAAAAA

Downstream 100 bases:

>100_bases
CGGACAACGGTCATCCTCTGCCGCCCTCCGGCAAGGGATGACCGCTTTGCCGGTTCACCAAAAACCACAAGCCATTGAAA
TAAAAGAACTTATTAGATGG

Product: general substrate transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MDQPMTAHAPAAQRDGIDPIRAAQISARIDRLPAVATIWRLVALLSIGGFFELYDLFQTAYISPGLIRDGIFAIGNQGVF
GFSDQAAFASATFLGLFLGASLLSPMADRFGRRAIFTFALVWYTVATVLMGVQSSALGIICMRFLVGIGLGIELVTIDAY
LSELVPKRMRSSAFAFAFFVQFLSVPAVALMSWWLVPQAPFGISGWRWVVLASAVFALFIWWLRKRLPESPRWLAQHGRF
DEANRILDGIEARCEKDHRQPLDAPEAVAVDVEGKGRFADIWQPPYRRRALMLIVFHIFQAIGFFGFGNWLPALLSGQGV
SVTHSLMYAFIITLAYPLGPLLFVKFANRFENKWQIVGSALGAMTFGTLFALQTSAVGLIFCGVMITFCNAWLSFSYHSY
QSELFPTNIRARAVGFCYSFSRLSTVFSSLLIGLFLDHFGTPGVLAFIVASMLIVMLTIGCFGPRTRNLALENIAHR

Sequences:

>Translated_477_residues
MDQPMTAHAPAAQRDGIDPIRAAQISARIDRLPAVATIWRLVALLSIGGFFELYDLFQTAYISPGLIRDGIFAIGNQGVF
GFSDQAAFASATFLGLFLGASLLSPMADRFGRRAIFTFALVWYTVATVLMGVQSSALGIICMRFLVGIGLGIELVTIDAY
LSELVPKRMRSSAFAFAFFVQFLSVPAVALMSWWLVPQAPFGISGWRWVVLASAVFALFIWWLRKRLPESPRWLAQHGRF
DEANRILDGIEARCEKDHRQPLDAPEAVAVDVEGKGRFADIWQPPYRRRALMLIVFHIFQAIGFFGFGNWLPALLSGQGV
SVTHSLMYAFIITLAYPLGPLLFVKFANRFENKWQIVGSALGAMTFGTLFALQTSAVGLIFCGVMITFCNAWLSFSYHSY
QSELFPTNIRARAVGFCYSFSRLSTVFSSLLIGLFLDHFGTPGVLAFIVASMLIVMLTIGCFGPRTRNLALENIAHR
>Mature_477_residues
MDQPMTAHAPAAQRDGIDPIRAAQISARIDRLPAVATIWRLVALLSIGGFFELYDLFQTAYISPGLIRDGIFAIGNQGVF
GFSDQAAFASATFLGLFLGASLLSPMADRFGRRAIFTFALVWYTVATVLMGVQSSALGIICMRFLVGIGLGIELVTIDAY
LSELVPKRMRSSAFAFAFFVQFLSVPAVALMSWWLVPQAPFGISGWRWVVLASAVFALFIWWLRKRLPESPRWLAQHGRF
DEANRILDGIEARCEKDHRQPLDAPEAVAVDVEGKGRFADIWQPPYRRRALMLIVFHIFQAIGFFGFGNWLPALLSGQGV
SVTHSLMYAFIITLAYPLGPLLFVKFANRFENKWQIVGSALGAMTFGTLFALQTSAVGLIFCGVMITFCNAWLSFSYHSY
QSELFPTNIRARAVGFCYSFSRLSTVFSSLLIGLFLDHFGTPGVLAFIVASMLIVMLTIGCFGPRTRNLALENIAHR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI7662270, Length=394, Percent_Identity=22.3350253807107, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI166064021, Length=401, Percent_Identity=24.9376558603491, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI262399383, Length=313, Percent_Identity=23.961661341853, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI216548223, Length=291, Percent_Identity=21.6494845360825, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI24308167, Length=420, Percent_Identity=21.4285714285714, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI24497497, Length=366, Percent_Identity=27.5956284153005, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI90669191, Length=366, Percent_Identity=27.5956284153005, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI296080734, Length=367, Percent_Identity=26.158038147139, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI296080719, Length=367, Percent_Identity=26.7029972752044, Blast_Score=66, Evalue=7e-11,
Organism=Homo sapiens, GI24497499, Length=367, Percent_Identity=26.7029972752044, Blast_Score=66, Evalue=7e-11,
Organism=Homo sapiens, GI296080721, Length=367, Percent_Identity=26.7029972752044, Blast_Score=66, Evalue=7e-11,
Organism=Homo sapiens, GI203098995, Length=298, Percent_Identity=24.8322147651007, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI1788068, Length=468, Percent_Identity=26.7094017094017, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1788074, Length=441, Percent_Identity=26.984126984127, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1786229, Length=408, Percent_Identity=25.9803921568627, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI87082159, Length=355, Percent_Identity=29.2957746478873, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI87082404, Length=393, Percent_Identity=23.6641221374046, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI87082231, Length=187, Percent_Identity=28.8770053475936, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1789207, Length=417, Percent_Identity=23.9808153477218, Blast_Score=62, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17537965, Length=407, Percent_Identity=23.8329238329238, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17565978, Length=271, Percent_Identity=23.2472324723247, Blast_Score=65, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6320595, Length=155, Percent_Identity=28.3870967741935, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321068, Length=441, Percent_Identity=20.1814058956916, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19922616, Length=365, Percent_Identity=25.4794520547945, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24640198, Length=506, Percent_Identity=23.7154150197628, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24640196, Length=506, Percent_Identity=23.7154150197628, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24640200, Length=506, Percent_Identity=23.7154150197628, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 52842; Mature: 52842

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1 ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQPMTAHAPAAQRDGIDPIRAAQISARIDRLPAVATIWRLVALLSIGGFFELYDLFQTA
CCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
YISPGLIRDGIFAIGNQGVFGFSDQAAFASATFLGLFLGASLLSPMADRFGRRAIFTFAL
HCCCCHHHCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
VWYTVATVLMGVQSSALGIICMRFLVGIGLGIELVTIDAYLSELVPKRMRSSAFAFAFFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHH
QFLSVPAVALMSWWLVPQAPFGISGWRWVVLASAVFALFIWWLRKRLPESPRWLAQHGRF
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCC
DEANRILDGIEARCEKDHRQPLDAPEAVAVDVEGKGRFADIWQPPYRRRALMLIVFHIFQ
CHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHH
AIGFFGFGNWLPALLSGQGVSVTHSLMYAFIITLAYPLGPLLFVKFANRFENKWQIVGSA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGAMTFGTLFALQTSAVGLIFCGVMITFCNAWLSFSYHSYQSELFPTNIRARAVGFCYSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHH
SRLSTVFSSLLIGLFLDHFGTPGVLAFIVASMLIVMLTIGCFGPRTRNLALENIAHR
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCC
>Mature Secondary Structure
MDQPMTAHAPAAQRDGIDPIRAAQISARIDRLPAVATIWRLVALLSIGGFFELYDLFQTA
CCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
YISPGLIRDGIFAIGNQGVFGFSDQAAFASATFLGLFLGASLLSPMADRFGRRAIFTFAL
HCCCCHHHCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
VWYTVATVLMGVQSSALGIICMRFLVGIGLGIELVTIDAYLSELVPKRMRSSAFAFAFFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHH
QFLSVPAVALMSWWLVPQAPFGISGWRWVVLASAVFALFIWWLRKRLPESPRWLAQHGRF
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCC
DEANRILDGIEARCEKDHRQPLDAPEAVAVDVEGKGRFADIWQPPYRRRALMLIVFHIFQ
CHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHH
AIGFFGFGNWLPALLSGQGVSVTHSLMYAFIITLAYPLGPLLFVKFANRFENKWQIVGSA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGAMTFGTLFALQTSAVGLIFCGVMITFCNAWLSFSYHSYQSELFPTNIRARAVGFCYSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHH
SRLSTVFSSLLIGLFLDHFGTPGVLAFIVASMLIVMLTIGCFGPRTRNLALENIAHR
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 8011666; 9384377 [H]