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The map label for this gene is gntR [H]

Identifier: 77460558

GI number: 77460558

Start: 4891094

End: 4892125

Strand: Direct

Name: gntR [H]

Synonym: Pfl01_4337

Alternate gene names: 77460558

Gene position: 4891094-4892125 (Clockwise)

Preceding gene: 77460555

Following gene: 77460560

Centisome position: 75.97

GC content: 61.92

Gene sequence:

>1032_bases
ATGACCACCCCTAAAAACGATAAAAACACCCGCACCACCGGCCGTCCCACCCTTAATGAAGTCGCCCGTCTGGCCGGCGT
CAGCCCGATTACCGCCTCCCGCGCCCTGCGTGGGGTCAGCACGGTCGCCACCGAATTGGTGGAAAAAGTCCAGAAAGCCG
CGCTGGAACTCAACTATGTGGTTAACCCCGCCGCCCGCGCTCTGGCCTCGGCCCAGAGCCATTCGGTGGTGGTTCTGGTG
CCTTCGCTGTCCAACTTGCTGTTCATCGACACCCTGGAAGCCATTCATCGGGTACTGACGCCCAAAGGTTTCGAGGTGCT
GATCGGCAACTTCCACTATTCCCGCGATGAAGAAGAAAACCTGCTGCGCAACTACATGGCCTATCAGCCACGCGGCTTGC
TGCTGACCGGCTTTGACCGCACCGAAAGTTCGCGGTGGATGATCGAGGCCAGCAATATTCCCTGCGTGTACATGATGGAA
CTGGACAGCGCCGCCGGGGTGAACTGTGTCGGCTTCTCCCAGCTCAGCGCCGGGGAAACGGCTGCCGAACATTTGCTGTC
CCGTGGCCGCAAGCGTCTGGCGTACATCGGCGCGCAACTCGATCAGCGCACCCTGCTGCGCGGTGAAGGCTTTCGCAAGG
CGTTGCAGAAGGCCGGTCGCTACGACCCGGATCTGGAAGTGCTGACCCCGCGTTCATCGTCCGTGGGCCTGGGTGGCGAG
TTGTTCCTGCAATTGCTGGCGGCGCATCCGGATGTCGATGCGATCTTCTTCGGCAACGACGACCTGGCTCAGGGCGCCTT
GCTCGAAGCGCTGCGCAACGGGATCAGGATCCCCGAGCAAGTAGCGATCCTCGGCTTCAACGACCTGCCGATGTCGGAGC
ACATGGTGCCGCGCCTTAGCAGCATCAATACGCCCCGCGAAGCGATCGGCAAGCGTGCGGCGGAGCAGATGCTGACACTG
ATGGCCGGCAACAGTGTGGCGCGGCCGGTCGAAGACATGGGCTTCGAGCTGAAGATTCGCGAGAGCACCTGA

Upstream 100 bases:

>100_bases
GCCAAAAAGCGAGGATCAGGCAGGACCTCGCTTACGCATTTGCAGCTGCATAAGGACAGCGCTACCTTAGTGCCTTGATT
TTTGTTTGGCAAGCCGCCCG

Downstream 100 bases:

>100_bases
CTCAACCGCCCAGCAACTCCACCAGAGCCAGCGCGCCCTTCTGCAGCGGCTGGCTCTTGAGCCACACCGCGTGCACCGGC
AGCACCAGGCCGTTTTCGAT

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Gluconate utilization system GNT-I transcriptional repressor [H]

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MTTPKNDKNTRTTGRPTLNEVARLAGVSPITASRALRGVSTVATELVEKVQKAALELNYVVNPAARALASAQSHSVVVLV
PSLSNLLFIDTLEAIHRVLTPKGFEVLIGNFHYSRDEEENLLRNYMAYQPRGLLLTGFDRTESSRWMIEASNIPCVYMME
LDSAAGVNCVGFSQLSAGETAAEHLLSRGRKRLAYIGAQLDQRTLLRGEGFRKALQKAGRYDPDLEVLTPRSSSVGLGGE
LFLQLLAAHPDVDAIFFGNDDLAQGALLEALRNGIRIPEQVAILGFNDLPMSEHMVPRLSSINTPREAIGKRAAEQMLTL
MAGNSVARPVEDMGFELKIREST

Sequences:

>Translated_343_residues
MTTPKNDKNTRTTGRPTLNEVARLAGVSPITASRALRGVSTVATELVEKVQKAALELNYVVNPAARALASAQSHSVVVLV
PSLSNLLFIDTLEAIHRVLTPKGFEVLIGNFHYSRDEEENLLRNYMAYQPRGLLLTGFDRTESSRWMIEASNIPCVYMME
LDSAAGVNCVGFSQLSAGETAAEHLLSRGRKRLAYIGAQLDQRTLLRGEGFRKALQKAGRYDPDLEVLTPRSSSVGLGGE
LFLQLLAAHPDVDAIFFGNDDLAQGALLEALRNGIRIPEQVAILGFNDLPMSEHMVPRLSSINTPREAIGKRAAEQMLTL
MAGNSVARPVEDMGFELKIREST
>Mature_342_residues
TTPKNDKNTRTTGRPTLNEVARLAGVSPITASRALRGVSTVATELVEKVQKAALELNYVVNPAARALASAQSHSVVVLVP
SLSNLLFIDTLEAIHRVLTPKGFEVLIGNFHYSRDEEENLLRNYMAYQPRGLLLTGFDRTESSRWMIEASNIPCVYMMEL
DSAAGVNCVGFSQLSAGETAAEHLLSRGRKRLAYIGAQLDQRTLLRGEGFRKALQKAGRYDPDLEVLTPRSSSVGLGGEL
FLQLLAAHPDVDAIFFGNDDLAQGALLEALRNGIRIPEQVAILGFNDLPMSEHMVPRLSSINTPREAIGKRAAEQMLTLM
AGNSVARPVEDMGFELKIREST

Specific function: Negative regulator for the gluconate utilization system GNT-I, the gntUKR operon [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994940, Length=323, Percent_Identity=35.6037151702786, Blast_Score=201, Evalue=8e-53,
Organism=Escherichia coli, GI1790715, Length=325, Percent_Identity=33.5384615384615, Blast_Score=187, Evalue=9e-49,
Organism=Escherichia coli, GI1790369, Length=330, Percent_Identity=29.6969696969697, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1790194, Length=307, Percent_Identity=28.0130293159609, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1788474, Length=319, Percent_Identity=29.7805642633229, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1787948, Length=309, Percent_Identity=26.8608414239482, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1789068, Length=320, Percent_Identity=25.3125, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786540, Length=314, Percent_Identity=26.4331210191083, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1789202, Length=300, Percent_Identity=26, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787580, Length=324, Percent_Identity=25.3086419753086, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786268, Length=277, Percent_Identity=28.158844765343, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787906, Length=326, Percent_Identity=26.6871165644172, Blast_Score=79, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37485; Mature: 37354

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPKNDKNTRTTGRPTLNEVARLAGVSPITASRALRGVSTVATELVEKVQKAALELNYV
CCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
VNPAARALASAQSHSVVVLVPSLSNLLFIDTLEAIHRVLTPKGFEVLIGNFHYSRDEEEN
ECHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHH
LLRNYMAYQPRGLLLTGFDRTESSRWMIEASNIPCVYMMELDSAAGVNCVGFSQLSAGET
HHHHHHHCCCCCCEEECCCCCCCCCEEEEECCCCEEEEEEECCCCCCCEEECCCCCCCHH
AAEHLLSRGRKRLAYIGAQLDQRTLLRGEGFRKALQKAGRYDPDLEVLTPRSSSVGLGGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCEEECCCCCCCCCCHH
LFLQLLAAHPDVDAIFFGNDDLAQGALLEALRNGIRIPEQVAILGFNDLPMSEHMVPRLS
HHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHH
SINTPREAIGKRAAEQMLTLMAGNSVARPVEDMGFELKIREST
HCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCEEEEECCC
>Mature Secondary Structure 
TTPKNDKNTRTTGRPTLNEVARLAGVSPITASRALRGVSTVATELVEKVQKAALELNYV
CCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
VNPAARALASAQSHSVVVLVPSLSNLLFIDTLEAIHRVLTPKGFEVLIGNFHYSRDEEEN
ECHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHH
LLRNYMAYQPRGLLLTGFDRTESSRWMIEASNIPCVYMMELDSAAGVNCVGFSQLSAGET
HHHHHHHCCCCCCEEECCCCCCCCCEEEEECCCCEEEEEEECCCCCCCEEECCCCCCCHH
AAEHLLSRGRKRLAYIGAQLDQRTLLRGEGFRKALQKAGRYDPDLEVLTPRSSSVGLGGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCEEECCCCCCCCCCHH
LFLQLLAAHPDVDAIFFGNDDLAQGALLEALRNGIRIPEQVAILGFNDLPMSEHMVPRLS
HHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHH
SINTPREAIGKRAAEQMLTLMAGNSVARPVEDMGFELKIREST
HCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]