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The map label for this gene is yfdZ [H]

Identifier: 77460555

GI number: 77460555

Start: 4887623

End: 4888831

Strand: Direct

Name: yfdZ [H]

Synonym: Pfl01_4334

Alternate gene names: 77460555

Gene position: 4887623-4888831 (Clockwise)

Preceding gene: 77460551

Following gene: 77460558

Centisome position: 75.91

GC content: 62.78

Gene sequence:

>1209_bases
ATGGCTGAACAAGGTTCGCCGCGCCGCTTTGCGCGCATTGATCGACTCCCCCCTTACGTTTTCAACATCACCGCCGAACT
GAAGATGGCCGCGCGACGTCGTGGCGAAGACATCATCGACTTGAGCATGGGCAACCCCGACGGCGCCACACCGCCGCACA
TCGTTGAAAAACTGGTGCAGGTTGCACAACGCGAAGACACCCACGGCTACTCCACGTCCAAGGGCATTCCGCGCCTGCGC
CGGGCGATTTCCAACTGGTACAAGGAACGCTACGAGGTCGAGATCGACCCGGAAAGCGAAGCCATCGTCACCATCGGTTC
CAAGGAAGGCTTGGCGCACCTGATGCTGGCGACCCTGGATCAGGGCGACACCGTGCTGGTGCCGAACCCGAGCTACCCGA
TTCACATCTACGGTGCCGTGATTGCCGGCGCCCAGGTGCGGTCAGTGCCACTGGTGCCGGGCGTGGATTTCTTCGCCGAG
CTGGAGCGGGCGATTCGCGGCTCGATCCCGAAACCGAAGATGATGATCCTCGGCTTCCCGTCGAACCCGACCGCGCAGTG
CGTGGAGCTCGACTTCTTCGAACGGGTGATCGCCCTCGCCAAACAGTACGACGTGCTGGTGGTGCACGACCTGGCTTACG
CCGACATCGTCTACGACGGCTGGAAAGCCCCGTCGATCATGCAGGTGCCGGGCGCCAAGGACATGGCGGTGGAGTTCTTC
ACCCTGTCCAAGAGCTACAACATGGCGGGCTGGCGCATCGGCTTCATGGTCGGCAACCCGGAACTGGTCAGCGCCCTGGC
GCGGATCAAGAGCTACCACGACTACGGCACCTTCACCCCGCTGCAGGTGGCCGCGATTGCTGCGCTGGAAGGTGATCAGC
AATGCGTGCGCGACATCGCCGAACAGTATCGCCAGCGCCGCAACGTGCTGGTCAAAGGCCTGCATGAACTGGGCTGGATG
GTCGAGAACCCGAAAGCCTCGATGTACGTGTGGGCGAAGATTCCCGAAGCCTACGCGCACCTCGGCTCGCTGGAGTTCGC
CAAGAAGCTGCTGGCCGAGGCCAAGGTCTGCGTCTCGCCAGGTGTCGGCTTTGGCGAGTACGGCGACGATCACGTGCGCT
TCGCGCTGATCGAAAACCAGGACCGGATTCGCCAGGCGGTACGCGGGATTCGCGGAATGTTCCGGGCGGATGCTCTGGGC
ACCAAGTAA

Upstream 100 bases:

>100_bases
TGGACAGTCTGCCATCGCTGCCCTTATCGTCCGCCACAGGTCACCACAGTGACCAGCGTCGCTCGGACGGTTCCGGGCGC
TTACGTTATCCGAGGCAACA

Downstream 100 bases:

>100_bases
CTCGCGAATTGCACCCACAAAAAAACCGCATCACTGCGGTTTTTTTGTGTCTGCATCTTCTTGAACGAAGAGAGTCTTAA
ACGAACAGCGACAACAACAG

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MAEQGSPRRFARIDRLPPYVFNITAELKMAARRRGEDIIDLSMGNPDGATPPHIVEKLVQVAQREDTHGYSTSKGIPRLR
RAISNWYKERYEVEIDPESEAIVTIGSKEGLAHLMLATLDQGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVPGVDFFAE
LERAIRGSIPKPKMMILGFPSNPTAQCVELDFFERVIALAKQYDVLVVHDLAYADIVYDGWKAPSIMQVPGAKDMAVEFF
TLSKSYNMAGWRIGFMVGNPELVSALARIKSYHDYGTFTPLQVAAIAALEGDQQCVRDIAEQYRQRRNVLVKGLHELGWM
VENPKASMYVWAKIPEAYAHLGSLEFAKKLLAEAKVCVSPGVGFGEYGDDHVRFALIENQDRIRQAVRGIRGMFRADALG
TK

Sequences:

>Translated_402_residues
MAEQGSPRRFARIDRLPPYVFNITAELKMAARRRGEDIIDLSMGNPDGATPPHIVEKLVQVAQREDTHGYSTSKGIPRLR
RAISNWYKERYEVEIDPESEAIVTIGSKEGLAHLMLATLDQGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVPGVDFFAE
LERAIRGSIPKPKMMILGFPSNPTAQCVELDFFERVIALAKQYDVLVVHDLAYADIVYDGWKAPSIMQVPGAKDMAVEFF
TLSKSYNMAGWRIGFMVGNPELVSALARIKSYHDYGTFTPLQVAAIAALEGDQQCVRDIAEQYRQRRNVLVKGLHELGWM
VENPKASMYVWAKIPEAYAHLGSLEFAKKLLAEAKVCVSPGVGFGEYGDDHVRFALIENQDRIRQAVRGIRGMFRADALG
TK
>Mature_401_residues
AEQGSPRRFARIDRLPPYVFNITAELKMAARRRGEDIIDLSMGNPDGATPPHIVEKLVQVAQREDTHGYSTSKGIPRLRR
AISNWYKERYEVEIDPESEAIVTIGSKEGLAHLMLATLDQGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVPGVDFFAEL
ERAIRGSIPKPKMMILGFPSNPTAQCVELDFFERVIALAKQYDVLVVHDLAYADIVYDGWKAPSIMQVPGAKDMAVEFFT
LSKSYNMAGWRIGFMVGNPELVSALARIKSYHDYGTFTPLQVAAIAALEGDQQCVRDIAEQYRQRRNVLVKGLHELGWMV
ENPKASMYVWAKIPEAYAHLGSLEFAKKLLAEAKVCVSPGVGFGEYGDDHVRFALIENQDRIRQAVRGIRGMFRADALGT
K

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=417, Percent_Identity=24.220623501199, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI56713256, Length=417, Percent_Identity=24.220623501199, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI95147551, Length=425, Percent_Identity=23.0588235294118, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI169881279, Length=425, Percent_Identity=23.0588235294118, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI169881281, Length=243, Percent_Identity=20.1646090534979, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI1788722, Length=399, Percent_Identity=88.7218045112782, Blast_Score=736, Evalue=0.0,
Organism=Escherichia coli, GI1786816, Length=372, Percent_Identity=25.8064516129032, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788627, Length=377, Percent_Identity=27.3209549071618, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788332, Length=227, Percent_Identity=28.1938325991189, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71994472, Length=371, Percent_Identity=24.7978436657682, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71994476, Length=371, Percent_Identity=24.7978436657682, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17567369, Length=398, Percent_Identity=23.6180904522613, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17567663, Length=373, Percent_Identity=23.0563002680965, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322401, Length=390, Percent_Identity=21.025641025641, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320317, Length=350, Percent_Identity=24.5714285714286, Blast_Score=87, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6323118, Length=352, Percent_Identity=23.8636363636364, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28573069, Length=410, Percent_Identity=25.3658536585366, Blast_Score=124, Evalue=9e-29,
Organism=Drosophila melanogaster, GI24646114, Length=410, Percent_Identity=25.3658536585366, Blast_Score=124, Evalue=9e-29,
Organism=Drosophila melanogaster, GI28573067, Length=410, Percent_Identity=25.3658536585366, Blast_Score=124, Evalue=9e-29,
Organism=Drosophila melanogaster, GI28573065, Length=410, Percent_Identity=25.3658536585366, Blast_Score=124, Evalue=9e-29,
Organism=Drosophila melanogaster, GI18859735, Length=251, Percent_Identity=23.1075697211155, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 44735; Mature: 44604

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEQGSPRRFARIDRLPPYVFNITAELKMAARRRGEDIIDLSMGNPDGATPPHIVEKLVQ
CCCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHH
VAQREDTHGYSTSKGIPRLRRAISNWYKERYEVEIDPESEAIVTIGSKEGLAHLMLATLD
HHHCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCEEEEECCCCCHHHHHHHHCC
QGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVPGVDFFAELERAIRGSIPKPKMMILGFP
CCCEEEECCCCCCEEEEEEECCCCEECCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECC
SNPTAQCVELDFFERVIALAKQYDVLVVHDLAYADIVYDGWKAPSIMQVPGAKDMAVEFF
CCCCCHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHEECCCCCCCEEECCCCCHHEEEEE
TLSKSYNMAGWRIGFMVGNPELVSALARIKSYHDYGTFTPLQVAAIAALEGDQQCVRDIA
EECCCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHH
EQYRQRRNVLVKGLHELGWMVENPKASMYVWAKIPEAYAHLGSLEFAKKLLAEAKVCVSP
HHHHHHHHHHHHHHHHHCCEEECCCCCEEEEEECCHHHHHHCCHHHHHHHHHHHHHEECC
GVGFGEYGDDHVRFALIENQDRIRQAVRGIRGMFRADALGTK
CCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AEQGSPRRFARIDRLPPYVFNITAELKMAARRRGEDIIDLSMGNPDGATPPHIVEKLVQ
CCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHH
VAQREDTHGYSTSKGIPRLRRAISNWYKERYEVEIDPESEAIVTIGSKEGLAHLMLATLD
HHHCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCEEEEECCCCCHHHHHHHHCC
QGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVPGVDFFAELERAIRGSIPKPKMMILGFP
CCCEEEECCCCCCEEEEEEECCCCEECCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECC
SNPTAQCVELDFFERVIALAKQYDVLVVHDLAYADIVYDGWKAPSIMQVPGAKDMAVEFF
CCCCCHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHEECCCCCCCEEECCCCCHHEEEEE
TLSKSYNMAGWRIGFMVGNPELVSALARIKSYHDYGTFTPLQVAAIAALEGDQQCVRDIA
EECCCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHH
EQYRQRRNVLVKGLHELGWMVENPKASMYVWAKIPEAYAHLGSLEFAKKLLAEAKVCVSP
HHHHHHHHHHHHHHHHHCCEEECCCCCEEEEEECCHHHHHHCCHHHHHHHHHHHHHEECC
GVGFGEYGDDHVRFALIENQDRIRQAVRGIRGMFRADALGTK
CCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]