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The map label for this gene is hlyB [H]

Identifier: 77460538

GI number: 77460538

Start: 4872197

End: 4873819

Strand: Reverse

Name: hlyB [H]

Synonym: Pfl01_4317

Alternate gene names: 77460538

Gene position: 4873819-4872197 (Counterclockwise)

Preceding gene: 77460541

Following gene: 77460537

Centisome position: 75.7

GC content: 63.71

Gene sequence:

>1623_bases
ATGCTGCAAAAATCCCTGAGAGCGCAAATTCTCGCCCTGCTGAGCGGCAGCCTGCTGGCGATGCTGTTGATCGCGCTGGC
CTGCTTTCATTTCCTGTCCAACGGCGTGCAGAACTACAGCCAATTGATTGCAGGTCCGTTGCACACCTCGCAACTGATCG
ATGAAGCCAACCTGCAATTCAAGGTGCAGGTTCAGGAGTGGAAAAACGTTCTGCTGCGCGGCAAGCAACCGGCGGATCTG
GCCAAGTACTGGGGCCAGTTCGAAGACCGTCAGCGCGATGTGCAGAACATCCTCAGTGAGCTGGCCAACCAGAAAGGCCT
CGACCCTGCGTTGAAAACTCGTATCGAACGCCTGCGCGAAGAACATCGTCTGCTCGGCGCCGCGTACCAGAAGGGCCGTG
ATGCCTACGTCGCCACCGGTGCCGATCCGACTGCGGGCGATGCCGCCGTCAAAGGCGTCGACCGTGCCGCCAGCGACCAG
ATGAGCGAACTGGTCGCCGAGCTGCGCAAGCAGGGCACCGAGCAATCGGCGCAGATCAGCGCCAGTGCCGATCGCACCGT
GTGGCTGGGTCTGCTGGTGATGCTCGCGTCCGGTCTGCTGATCGGTTTGCTGAGCCTGTGGCTGGTCAACCGCAACCTGG
TCGAGCCGATCAGCAAACTGATCGACTACGTCACTCAACTGAGCAAGGGCCGTCTGGTCGAGCGCGTGGCCAGTGACCGT
CAGGACGAGCTGGGCAACCTGGCCGCCGCGGCCAACACCCTGCGCGATTTCCTCGCCGAAACCTTCAATCACCTGCAACG
CAGCGCCAAGGATCTGGACAGCGCCAGCGGCGAGTTGAACGCCATCGCCACGCTGATGGCCGGCGGCACCAACGAGCAGT
TCAACCGCACCGATCAGGTGGCCACGGCGATGAACGAAATGTCCGCCACTGCCCAGGAAGTCGCCCGTCATGCGGCCGAC
GCTGCGCGTGCGGCCGACGATGCTGACCAGTCCGCGCAGCAGGGCGAGAAGGTCATGCAGAGCACCATCCACAGCATCAC
CCAGATGCGCGGCGAAATCGCCAACACCGCCACGGTCATCCGTCGTCTGGAAGCCGACAGCGGTCGCATCGGCAAAGTGC
TGGAAGTGATTCGCGGGATCGCCGAGCAGACCAACCTGCTGGCGCTCAACGCCGCCATCGAAGCGGCCCGCGCGGGTGAG
GCCGGGCGTGGTTTTGCAGTGGTCGCCGATGAGGTGCGCAACCTCGCGCAGCGTACGGCGGAGTCGATCATCGAGATCAA
CCAGATCATCCACAGCGTGCAGACCGGTGCGGTGGACGCGGCCCAGGCCATCGACAGCGGCCAGACCCGCAGCGATGAAA
GCGTCGAGCAAGTGACCCAGGCCGGCGCCATGCTTGAGCGCATCACCCACGCGGTGGAAGCGATTCGCGACATGAACCGT
CAGATCGCCACGGCGGCCGAAGAGCAGACTTCGGTGGCCGAAGACATCTCGCGCAACCTGACCGAGATCACCTCGATCGC
CAGCACCAACCTCGACAACGTGCAGCGCACCGAGAGCGCCAGCCAGAACCTGCACGGCCTGTCCGGCCAACTGAACGACG
TCACCGCTCGCCTGAGCGTCTGA

Upstream 100 bases:

>100_bases
TTGCGCGCCTTCGGCCATGAGCCAAGGTCCGCCGACACGGATGTCCGGCCACAATTCACGTCTTACCGGGCGTGCCTCAT
CCCTGTCCTGAGTACCTGTG

Downstream 100 bases:

>100_bases
CCGGCCAGTGACTGTGTACCGGTTCGGATACCGAGTCGGTACACAGTCGATCTCAATGGGTGCAGACCGCCGCCGATGCC
CGGTTATCCATAACCGGCAT

Product: chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 540; Mature: 540

Protein sequence:

>540_residues
MLQKSLRAQILALLSGSLLAMLLIALACFHFLSNGVQNYSQLIAGPLHTSQLIDEANLQFKVQVQEWKNVLLRGKQPADL
AKYWGQFEDRQRDVQNILSELANQKGLDPALKTRIERLREEHRLLGAAYQKGRDAYVATGADPTAGDAAVKGVDRAASDQ
MSELVAELRKQGTEQSAQISASADRTVWLGLLVMLASGLLIGLLSLWLVNRNLVEPISKLIDYVTQLSKGRLVERVASDR
QDELGNLAAAANTLRDFLAETFNHLQRSAKDLDSASGELNAIATLMAGGTNEQFNRTDQVATAMNEMSATAQEVARHAAD
AARAADDADQSAQQGEKVMQSTIHSITQMRGEIANTATVIRRLEADSGRIGKVLEVIRGIAEQTNLLALNAAIEAARAGE
AGRGFAVVADEVRNLAQRTAESIIEINQIIHSVQTGAVDAAQAIDSGQTRSDESVEQVTQAGAMLERITHAVEAIRDMNR
QIATAAEEQTSVAEDISRNLTEITSIASTNLDNVQRTESASQNLHGLSGQLNDVTARLSV

Sequences:

>Translated_540_residues
MLQKSLRAQILALLSGSLLAMLLIALACFHFLSNGVQNYSQLIAGPLHTSQLIDEANLQFKVQVQEWKNVLLRGKQPADL
AKYWGQFEDRQRDVQNILSELANQKGLDPALKTRIERLREEHRLLGAAYQKGRDAYVATGADPTAGDAAVKGVDRAASDQ
MSELVAELRKQGTEQSAQISASADRTVWLGLLVMLASGLLIGLLSLWLVNRNLVEPISKLIDYVTQLSKGRLVERVASDR
QDELGNLAAAANTLRDFLAETFNHLQRSAKDLDSASGELNAIATLMAGGTNEQFNRTDQVATAMNEMSATAQEVARHAAD
AARAADDADQSAQQGEKVMQSTIHSITQMRGEIANTATVIRRLEADSGRIGKVLEVIRGIAEQTNLLALNAAIEAARAGE
AGRGFAVVADEVRNLAQRTAESIIEINQIIHSVQTGAVDAAQAIDSGQTRSDESVEQVTQAGAMLERITHAVEAIRDMNR
QIATAAEEQTSVAEDISRNLTEITSIASTNLDNVQRTESASQNLHGLSGQLNDVTARLSV
>Mature_540_residues
MLQKSLRAQILALLSGSLLAMLLIALACFHFLSNGVQNYSQLIAGPLHTSQLIDEANLQFKVQVQEWKNVLLRGKQPADL
AKYWGQFEDRQRDVQNILSELANQKGLDPALKTRIERLREEHRLLGAAYQKGRDAYVATGADPTAGDAAVKGVDRAASDQ
MSELVAELRKQGTEQSAQISASADRTVWLGLLVMLASGLLIGLLSLWLVNRNLVEPISKLIDYVTQLSKGRLVERVASDR
QDELGNLAAAANTLRDFLAETFNHLQRSAKDLDSASGELNAIATLMAGGTNEQFNRTDQVATAMNEMSATAQEVARHAAD
AARAADDADQSAQQGEKVMQSTIHSITQMRGEIANTATVIRRLEADSGRIGKVLEVIRGIAEQTNLLALNAAIEAARAGE
AGRGFAVVADEVRNLAQRTAESIIEINQIIHSVQTGAVDAAQAIDSGQTRSDESVEQVTQAGAMLERITHAVEAIRDMNR
QIATAAEEQTSVAEDISRNLTEITSIASTNLDNVQRTESASQNLHGLSGQLNDVTARLSV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=339, Percent_Identity=32.4483775811209, Blast_Score=149, Evalue=6e-37,
Organism=Escherichia coli, GI1788195, Length=305, Percent_Identity=31.8032786885246, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1787690, Length=384, Percent_Identity=27.0833333333333, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1788194, Length=364, Percent_Identity=28.021978021978, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1789453, Length=362, Percent_Identity=26.7955801104972, Blast_Score=97, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58324; Mature: 58324

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQKSLRAQILALLSGSLLAMLLIALACFHFLSNGVQNYSQLIAGPLHTSQLIDEANLQF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEE
KVQVQEWKNVLLRGKQPADLAKYWGQFEDRQRDVQNILSELANQKGLDPALKTRIERLRE
EEEHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
EHRLLGAAYQKGRDAYVATGADPTAGDAAVKGVDRAASDQMSELVAELRKQGTEQSAQIS
HHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHC
ASADRTVWLGLLVMLASGLLIGLLSLWLVNRNLVEPISKLIDYVTQLSKGRLVERVASDR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QDELGNLAAAANTLRDFLAETFNHLQRSAKDLDSASGELNAIATLMAGGTNEQFNRTDQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHH
ATAMNEMSATAQEVARHAADAARAADDADQSAQQGEKVMQSTIHSITQMRGEIANTATVI
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLEADSGRIGKVLEVIRGIAEQTNLLALNAAIEAARAGEAGRGFAVVADEVRNLAQRTA
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
ESIIEINQIIHSVQTGAVDAAQAIDSGQTRSDESVEQVTQAGAMLERITHAVEAIRDMNR
HHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIATAAEEQTSVAEDISRNLTEITSIASTNLDNVQRTESASQNLHGLSGQLNDVTARLSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCC
>Mature Secondary Structure
MLQKSLRAQILALLSGSLLAMLLIALACFHFLSNGVQNYSQLIAGPLHTSQLIDEANLQF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEE
KVQVQEWKNVLLRGKQPADLAKYWGQFEDRQRDVQNILSELANQKGLDPALKTRIERLRE
EEEHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
EHRLLGAAYQKGRDAYVATGADPTAGDAAVKGVDRAASDQMSELVAELRKQGTEQSAQIS
HHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHC
ASADRTVWLGLLVMLASGLLIGLLSLWLVNRNLVEPISKLIDYVTQLSKGRLVERVASDR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QDELGNLAAAANTLRDFLAETFNHLQRSAKDLDSASGELNAIATLMAGGTNEQFNRTDQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHH
ATAMNEMSATAQEVARHAADAARAADDADQSAQQGEKVMQSTIHSITQMRGEIANTATVI
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLEADSGRIGKVLEVIRGIAEQTNLLALNAAIEAARAGEAGRGFAVVADEVRNLAQRTA
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
ESIIEINQIIHSVQTGAVDAAQAIDSGQTRSDESVEQVTQAGAMLERITHAVEAIRDMNR
HHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIATAAEEQTSVAEDISRNLTEITSIASTNLDNVQRTESASQNLHGLSGQLNDVTARLSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]