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The map label for this gene is mauR [H]

Identifier: 77460531

GI number: 77460531

Start: 4867262

End: 4868176

Strand: Reverse

Name: mauR [H]

Synonym: Pfl01_4310

Alternate gene names: 77460531

Gene position: 4868176-4867262 (Counterclockwise)

Preceding gene: 77460534

Following gene: 77460526

Centisome position: 75.61

GC content: 64.15

Gene sequence:

>915_bases
TTGGCGTTCACGCACTCTAAATCGGCGTTTGCCCAAGTGATCAATGCAACCACGCAATACCGACTCGATTTCCCGGATCT
GGCCCTGATTCTCGCCTTAGTGCGCGGCGGCTCTCTGGCCCGGGCCGCACAGCTGATGAAGGTCGATGTGTCGACGGTGT
TTCGCGCAGTGCGCCGACTGGAAGCATCACTCGGCCAGCAACTGTTCGAAAAAAGCCGCGCCGGTTACCTGCCCACCAGC
CTCGCGCAGACCCTGGCCGAGCAGGCCGAACGCGCCGAGCAAGCTTTGGAAGCGGCGCGAATCGGCGTGGAGCAGGGCGG
TGAAGTGGTCAGCGGCACGGTGCGCCTGACTTGTACCGACTCCGTGCTGCAAGGTCTGCTGCTGCCGGCGCTGGCGCAGT
TCATGCCGAACTACCCGGCGCTGAGCATCGAACTGAGCACCTCCAATGATTTCGCCAACCTCAGCCGCCGCGATGCCGAC
ATCGCCCTGCGCCTGACGCGCACACCACCGGAGCATCTGGTCGGACGGGAGCTGGCGAAGATTTCCTACCGGGTCTGCGC
CAGTCAGCGTTATCTACAAAAGGTTGAAGCGGCCGATCTGGCGGCGCTGACCTGGATCGCCCCGGACGACTTTTTGCCCG
ATCACCCGACCGTCGCCTGGCGCCGCCAGCAGTTGCCGGGGGTGACTCCCAACTATCGCTGCAACAGCATGCTGTCTGTC
ACGGAGTTGGTCCGCGCCGGACTGGGCGTAGCGGCGTTGCCGGACTTTCTCATCAATGAGGGGCTGCTGGCCCTGAGCGA
ACCACTGCACGGTTATGACACCGCGCTGTGGCTGCTGACCCGCCCGGACTGCCGCGCGTTGCGCTCGGTGGTCACGTTGT
TCGACGAGTTGGGACGGGCGCTGAGGGTTTCGTGA

Upstream 100 bases:

>100_bases
CAGTAACTTGCGGGTCGAAGTCACCGATCAGGGCGATGCGCAGGGCTCTGGATTCCATGAGTACTCACTGTGCTTGTTGA
GGGATGAAGCTCACTATAGA

Downstream 100 bases:

>100_bases
TCAGCCCTGCTGGGTCTGGCGCATGTGATCGTGCAGTTCGCGGGTCAGGCCTTCGATGCGCTCGGTCAGGTTCTTGGTCA
TCTCCGTGAGTCGAGTGTTC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MAFTHSKSAFAQVINATTQYRLDFPDLALILALVRGGSLARAAQLMKVDVSTVFRAVRRLEASLGQQLFEKSRAGYLPTS
LAQTLAEQAERAEQALEAARIGVEQGGEVVSGTVRLTCTDSVLQGLLLPALAQFMPNYPALSIELSTSNDFANLSRRDAD
IALRLTRTPPEHLVGRELAKISYRVCASQRYLQKVEAADLAALTWIAPDDFLPDHPTVAWRRQQLPGVTPNYRCNSMLSV
TELVRAGLGVAALPDFLINEGLLALSEPLHGYDTALWLLTRPDCRALRSVVTLFDELGRALRVS

Sequences:

>Translated_304_residues
MAFTHSKSAFAQVINATTQYRLDFPDLALILALVRGGSLARAAQLMKVDVSTVFRAVRRLEASLGQQLFEKSRAGYLPTS
LAQTLAEQAERAEQALEAARIGVEQGGEVVSGTVRLTCTDSVLQGLLLPALAQFMPNYPALSIELSTSNDFANLSRRDAD
IALRLTRTPPEHLVGRELAKISYRVCASQRYLQKVEAADLAALTWIAPDDFLPDHPTVAWRRQQLPGVTPNYRCNSMLSV
TELVRAGLGVAALPDFLINEGLLALSEPLHGYDTALWLLTRPDCRALRSVVTLFDELGRALRVS
>Mature_303_residues
AFTHSKSAFAQVINATTQYRLDFPDLALILALVRGGSLARAAQLMKVDVSTVFRAVRRLEASLGQQLFEKSRAGYLPTSL
AQTLAEQAERAEQALEAARIGVEQGGEVVSGTVRLTCTDSVLQGLLLPALAQFMPNYPALSIELSTSNDFANLSRRDADI
ALRLTRTPPEHLVGRELAKISYRVCASQRYLQKVEAADLAALTWIAPDDFLPDHPTVAWRRQQLPGVTPNYRCNSMLSVT
ELVRAGLGVAALPDFLINEGLLALSEPLHGYDTALWLLTRPDCRALRSVVTLFDELGRALRVS

Specific function: Transcriptional activator of the mau genes involved in methylamine metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693193, Length=271, Percent_Identity=26.1992619926199, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1786401, Length=244, Percent_Identity=26.2295081967213, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789639, Length=243, Percent_Identity=22.6337448559671, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1789440, Length=169, Percent_Identity=24.8520710059172, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33285; Mature: 33153

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFTHSKSAFAQVINATTQYRLDFPDLALILALVRGGSLARAAQLMKVDVSTVFRAVRRL
CCCCCCHHHHHHHHHHHHHEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
EASLGQQLFEKSRAGYLPTSLAQTLAEQAERAEQALEAARIGVEQGGEVVSGTVRLTCTD
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCCEEECEEEEEECH
SVLQGLLLPALAQFMPNYPALSIELSTSNDFANLSRRDADIALRLTRTPPEHLVGRELAK
HHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHCCCCCEEEEEECCCHHHHHHHHHHH
ISYRVCASQRYLQKVEAADLAALTWIAPDDFLPDHPTVAWRRQQLPGVTPNYRCNSMLSV
HHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHCCCCCCCCCCCCHHHHH
TELVRAGLGVAALPDFLINEGLLALSEPLHGYDTALWLLTRPDCRALRSVVTLFDELGRA
HHHHHHCCCHHHHHHHHHHCCHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHH
LRVS
HCCC
>Mature Secondary Structure 
AFTHSKSAFAQVINATTQYRLDFPDLALILALVRGGSLARAAQLMKVDVSTVFRAVRRL
CCCCCHHHHHHHHHHHHHEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
EASLGQQLFEKSRAGYLPTSLAQTLAEQAERAEQALEAARIGVEQGGEVVSGTVRLTCTD
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCCEEECEEEEEECH
SVLQGLLLPALAQFMPNYPALSIELSTSNDFANLSRRDADIALRLTRTPPEHLVGRELAK
HHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHCCCCCEEEEEECCCHHHHHHHHHHH
ISYRVCASQRYLQKVEAADLAALTWIAPDDFLPDHPTVAWRRQQLPGVTPNYRCNSMLSV
HHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHCCCCCCCCCCCCHHHHH
TELVRAGLGVAALPDFLINEGLLALSEPLHGYDTALWLLTRPDCRALRSVVTLFDELGRA
HHHHHHCCCHHHHHHHHHHCCHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHH
LRVS
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7957249 [H]