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The map label for this gene is 77460526

Identifier: 77460526

GI number: 77460526

Start: 4862081

End: 4863154

Strand: Reverse

Name: 77460526

Synonym: Pfl01_4305

Alternate gene names: NA

Gene position: 4863154-4862081 (Counterclockwise)

Preceding gene: 77460531

Following gene: 77460525

Centisome position: 75.53

GC content: 60.15

Gene sequence:

>1074_bases
ATGGCCAAATCCATTGCTTCTGCGGGCAGTCAAACACCTGAACCTTCGCGTCAGGCCGAAGGCGTATTCCGCAACCACGC
GCCGTTGCAGCGCGAAGGTGTGCGCAAGATGCTGCGGATCATGTGGAACATGATCTTCCACAAACCGCGCAACACCCGGC
CGGCGGCAGCCATTCCGGTGCAGCCACTGACCCGCGCGGACCTGATCGCGGCGCCCAACCGCAGCGTCTATCGCCTCGGT
CATTCGACCCTGCTGCTCAAACTGCAGGACAAGTTCTGGATCACCGACCCAGTGTTCGCCGAGCGTGCCTCGCCCGTGCA
ATGGGCCGGCCCGAAACGCTTCCACCAGCCACCGATCAGCATCGATGAGTTGCCACCGATCGAAGCGGTGATCCTGTCGC
ATAACCACTACGACCACCTCGACTACGAAGCCGTGTTGAAACTGGCGGACAAGGTCAACGTGTTCCTGACCCCGCTGGGC
GTCGGCGATACCCTGATCAAATGGGGCATCGATGCCGACAAGGTTCGCCAGTTTGACTGGTGGCAGGGCACCGAAGTCGC
CGGCATCCGCTTCATCGCCACCCCGTCGCAGCACTTTTCCGGCCGGGGCCTGTTCGATGGCAACCAGACCCTGTGGGCTT
CGTGGGTGATCATTGATGACGACACGCGGATTTTCTTCAGCGGTGACAGCGGCTACTTCGATGGTTTTAAACGCATCGGT
GAACAGTACGGCCCCTTCGACCTGACCCTGATGGAGACCGGCGCCTACAACGTCGAATGGCCCCACGTGCACATGCAACC
GGAAGAATCCCTGCAAGCCCACATTGACCTCAAGGGGCGCTGGCTGTTTCCGATCCACAACGGCACGTTCGACCTGGCGA
TGCACGCTTGGCACGAGCCTTTCGATCGCATTCTTGCTTTGGCCTGGGAACGCAGTGTGTCGATAACCACGCCGAAGATG
GGCGAGGCGTTCAACCTGATGCAACCGCAACGTGGGGACGCGTGGTGGTTGGAAATGGAACAAGAGATGTCAGAAAAAGG
GCGTGTTGCTTGTAGCGGCTACAAGGCTGGGTGA

Upstream 100 bases:

>100_bases
ACCTAAAAACAGATGTCCGGCTGATGCGTGCGTGCCTTGGCCATTATCGTCCCACCGTGGAAAACCGTGAATTGCGCGGC
GTTTCCGGAGTCATTCAGTC

Downstream 100 bases:

>100_bases
GTTTTCCTACCGGCACTGGTTCTTGTTGCTGACAGCCGTTTCCTGCGGCTTCGGTAGGCTTGGTCGCGAGTGAAATGACT
CACTCGTGATTGGCTTAAAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MAKSIASAGSQTPEPSRQAEGVFRNHAPLQREGVRKMLRIMWNMIFHKPRNTRPAAAIPVQPLTRADLIAAPNRSVYRLG
HSTLLLKLQDKFWITDPVFAERASPVQWAGPKRFHQPPISIDELPPIEAVILSHNHYDHLDYEAVLKLADKVNVFLTPLG
VGDTLIKWGIDADKVRQFDWWQGTEVAGIRFIATPSQHFSGRGLFDGNQTLWASWVIIDDDTRIFFSGDSGYFDGFKRIG
EQYGPFDLTLMETGAYNVEWPHVHMQPEESLQAHIDLKGRWLFPIHNGTFDLAMHAWHEPFDRILALAWERSVSITTPKM
GEAFNLMQPQRGDAWWLEMEQEMSEKGRVACSGYKAG

Sequences:

>Translated_357_residues
MAKSIASAGSQTPEPSRQAEGVFRNHAPLQREGVRKMLRIMWNMIFHKPRNTRPAAAIPVQPLTRADLIAAPNRSVYRLG
HSTLLLKLQDKFWITDPVFAERASPVQWAGPKRFHQPPISIDELPPIEAVILSHNHYDHLDYEAVLKLADKVNVFLTPLG
VGDTLIKWGIDADKVRQFDWWQGTEVAGIRFIATPSQHFSGRGLFDGNQTLWASWVIIDDDTRIFFSGDSGYFDGFKRIG
EQYGPFDLTLMETGAYNVEWPHVHMQPEESLQAHIDLKGRWLFPIHNGTFDLAMHAWHEPFDRILALAWERSVSITTPKM
GEAFNLMQPQRGDAWWLEMEQEMSEKGRVACSGYKAG
>Mature_356_residues
AKSIASAGSQTPEPSRQAEGVFRNHAPLQREGVRKMLRIMWNMIFHKPRNTRPAAAIPVQPLTRADLIAAPNRSVYRLGH
STLLLKLQDKFWITDPVFAERASPVQWAGPKRFHQPPISIDELPPIEAVILSHNHYDHLDYEAVLKLADKVNVFLTPLGV
GDTLIKWGIDADKVRQFDWWQGTEVAGIRFIATPSQHFSGRGLFDGNQTLWASWVIIDDDTRIFFSGDSGYFDGFKRIGE
QYGPFDLTLMETGAYNVEWPHVHMQPEESLQAHIDLKGRWLFPIHNGTFDLAMHAWHEPFDRILALAWERSVSITTPKMG
EAFNLMQPQRGDAWWLEMEQEMSEKGRVACSGYKAG

Specific function: Unknown

COG id: COG2220

COG function: function code R; Predicted Zn-dependent hydrolases of the beta-lactamase fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To K.pneumoniae romA [H]

Homologues:

Organism=Homo sapiens, GI170932483, Length=276, Percent_Identity=38.768115942029, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI170932481, Length=276, Percent_Identity=38.768115942029, Blast_Score=203, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17543102, Length=282, Percent_Identity=35.8156028368794, Blast_Score=174, Evalue=8e-44,
Organism=Caenorhabditis elegans, GI17543100, Length=282, Percent_Identity=35.8156028368794, Blast_Score=173, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI25148824, Length=282, Percent_Identity=35.8156028368794, Blast_Score=173, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17543104, Length=285, Percent_Identity=35.0877192982456, Blast_Score=168, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6325154, Length=225, Percent_Identity=35.1111111111111, Blast_Score=120, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 40668; Mature: 40537

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKSIASAGSQTPEPSRQAEGVFRNHAPLQREGVRKMLRIMWNMIFHKPRNTRPAAAIPV
CCCCHHHCCCCCCCCCHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
QPLTRADLIAAPNRSVYRLGHSTLLLKLQDKFWITDPVFAERASPVQWAGPKRFHQPPIS
CCCCCCCEEECCCCCEEEECCEEEEEEEECCEEECCCHHHHCCCCCCCCCCCCCCCCCCC
IDELPPIEAVILSHNHYDHLDYEAVLKLADKVNVFLTPLGVGDTLIKWGIDADKVRQFDW
CCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCEEEEEECCCCCHHHCCCCCHHHHCCCCC
WQGTEVAGIRFIATPSQHFSGRGLFDGNQTLWASWVIIDDDTRIFFSGDSGYFDGFKRIG
CCCCCCCCEEEEECCCCCCCCCCEECCCCEEEEEEEEEECCCEEEEECCCCHHHHHHHHH
EQYGPFDLTLMETGAYNVEWPHVHMQPEESLQAHIDLKGRWLFPIHNGTFDLAMHAWHEP
HHCCCEEEEEEECCCCCEECCEEECCCHHHCEEEEEECCEEEEEEECCCEEEHHHHHHHH
FDRILALAWERSVSITTPKMGEAFNLMQPQRGDAWWLEMEQEMSEKGRVACSGYKAG
HHHHHHHHHHCCEEEECCCCCCHHCCCCCCCCCEEEEEEHHHHHHCCCEEECCCCCC
>Mature Secondary Structure 
AKSIASAGSQTPEPSRQAEGVFRNHAPLQREGVRKMLRIMWNMIFHKPRNTRPAAAIPV
CCCHHHCCCCCCCCCHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
QPLTRADLIAAPNRSVYRLGHSTLLLKLQDKFWITDPVFAERASPVQWAGPKRFHQPPIS
CCCCCCCEEECCCCCEEEECCEEEEEEEECCEEECCCHHHHCCCCCCCCCCCCCCCCCCC
IDELPPIEAVILSHNHYDHLDYEAVLKLADKVNVFLTPLGVGDTLIKWGIDADKVRQFDW
CCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCEEEEEECCCCCHHHCCCCCHHHHCCCCC
WQGTEVAGIRFIATPSQHFSGRGLFDGNQTLWASWVIIDDDTRIFFSGDSGYFDGFKRIG
CCCCCCCCEEEEECCCCCCCCCCEECCCCEEEEEEEEEECCCEEEEECCCCHHHHHHHHH
EQYGPFDLTLMETGAYNVEWPHVHMQPEESLQAHIDLKGRWLFPIHNGTFDLAMHAWHEP
HHCCCEEEEEEECCCCCEECCEEECCCHHHCEEEEEECCEEEEEEECCCEEEHHHHHHHH
FDRILALAWERSVSITTPKMGEAFNLMQPQRGDAWWLEMEQEMSEKGRVACSGYKAG
HHHHHHHHHHCCEEEECCCCCCHHCCCCCCCCCEEEEEEHHHHHHCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]