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The map label for this gene is argD [H]

Identifier: 77460506

GI number: 77460506

Start: 4834237

End: 4835457

Strand: Reverse

Name: argD [H]

Synonym: Pfl01_4285

Alternate gene names: 77460506

Gene position: 4835457-4834237 (Counterclockwise)

Preceding gene: 77460508

Following gene: 77460505

Centisome position: 75.1

GC content: 63.55

Gene sequence:

>1221_bases
ATGTCCGTTGAGCACGCTGCGGTACAACGCGCCGATTTCGACCAGGTTATGGTTCCCAACTACGCGCCTGCCGCTTTCAT
TCCGGTGCGTGGCGCCGGGTCCCGCGTCTGGGATCAGGCCGGCCGCGAGCTGATCGACTTCGCCGGCGGCATCGCCGTCA
ACGTATTGGGCCATGCGCACCCGGCGCTGGTCGGTGCCTTGACCGAGCAAGCGAACAAGCTGTGGCACGTGTCCAACGTG
TTCACCAACGAGCCGGCCCTGCGCCTGGCGCACAAGCTGATCGACGCCACCTTTGCCGAGCGCGTGTTCTTCTGCAACTC
CGGCGCCGAAGCCAACGAGGCCGCCTTCAAGCTGGCCCGTCGTGTCGCGTTCGACCGTTTCGGCACCGAGAAATACGAAA
TCATCGCCGCGCTCAACAGCTTCCACGGCCGTACTCTGTTCACCGTGAACGTCGGTGGCCAGTCGAAGTACTCCGACGGT
TTCGGTCCGAAAATCACCGGCATCACCCACGTACCGTACAACGATCTGGCGGCGCTGAAAGCCGCTGTTTCGGACAAGAC
CTGCGCGGTCGTTCTGGAACCGATCCAGGGCGAGGGCGGCGTGCTGCCGGCCGAGCTGGCTTACCTGCAAGGCGCCCGTG
AATTGTGCGACGCCAACAACGCGCTGCTGGTGTTCGACGAAGTGCAGACTGGCATGGGCCGTACCGGCAACCTGTTCGCC
TACCAGCATTACGGCGTGACCCCGGACATCCTGACCAGCGCCAAGAGCCTGGGCGGCGGTTTCCCGATCGCGGCGATGCT
GACCACCGAAGCGCTGGCCAAGCATCTGGTCGTCGGCACTCACGGCACCACTTATGGCGGCAACCCGCTGGCGTGTGCCG
TGGCCGAAGCGGTGATCGACGTGATCAACACCCCTGAGGTGCTGAACGGCGTCCATGCCAAGCACGACAAGTTCAAGACC
CGCCTGCAACAGATCGGCGAGAAGTACGGCCTGTTCACCCAGGTGCGTGGTCTCGGTCTGCTGATCGGTTGCGTGCTGAG
CGACGCCTGGAAAGGCAAGGCCAAGGACATCTTCAACGCCGCTGAACAAGAAGGCCTGATGATTCTGCAGGCCGGTCCGG
ACGTGATCCGTTTCGCCCCGAGCCTGGTGGTGGAAGACGCAGACATCGACGCCGGTCTGGATCGCTTCGAGCGTGCTGCG
GCGAAATTGACCCAAGCCTGA

Upstream 100 bases:

>100_bases
AGAAGTTGTCGCTTGGCGGCAAGGCCGGGCACAAAACTGTCCTTACAATCCCCCCATCGCTCGCCAGTTTCAGGCGGGTG
GCCCTCATCAGGAGACTCCG

Downstream 100 bases:

>100_bases
TTCATGCAAGACCGCCCGGCGTCTGTCGTCATCGACAGGTGCCGGGACCATTTTCCTGTGCCGGGCCTGCCCGGCATTTT
TTTCCCGAGTCGGCGCTTTC

Product: bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT 1 [H]

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MSVEHAAVQRADFDQVMVPNYAPAAFIPVRGAGSRVWDQAGRELIDFAGGIAVNVLGHAHPALVGALTEQANKLWHVSNV
FTNEPALRLAHKLIDATFAERVFFCNSGAEANEAAFKLARRVAFDRFGTEKYEIIAALNSFHGRTLFTVNVGGQSKYSDG
FGPKITGITHVPYNDLAALKAAVSDKTCAVVLEPIQGEGGVLPAELAYLQGARELCDANNALLVFDEVQTGMGRTGNLFA
YQHYGVTPDILTSAKSLGGGFPIAAMLTTEALAKHLVVGTHGTTYGGNPLACAVAEAVIDVINTPEVLNGVHAKHDKFKT
RLQQIGEKYGLFTQVRGLGLLIGCVLSDAWKGKAKDIFNAAEQEGLMILQAGPDVIRFAPSLVVEDADIDAGLDRFERAA
AKLTQA

Sequences:

>Translated_406_residues
MSVEHAAVQRADFDQVMVPNYAPAAFIPVRGAGSRVWDQAGRELIDFAGGIAVNVLGHAHPALVGALTEQANKLWHVSNV
FTNEPALRLAHKLIDATFAERVFFCNSGAEANEAAFKLARRVAFDRFGTEKYEIIAALNSFHGRTLFTVNVGGQSKYSDG
FGPKITGITHVPYNDLAALKAAVSDKTCAVVLEPIQGEGGVLPAELAYLQGARELCDANNALLVFDEVQTGMGRTGNLFA
YQHYGVTPDILTSAKSLGGGFPIAAMLTTEALAKHLVVGTHGTTYGGNPLACAVAEAVIDVINTPEVLNGVHAKHDKFKT
RLQQIGEKYGLFTQVRGLGLLIGCVLSDAWKGKAKDIFNAAEQEGLMILQAGPDVIRFAPSLVVEDADIDAGLDRFERAA
AKLTQA
>Mature_405_residues
SVEHAAVQRADFDQVMVPNYAPAAFIPVRGAGSRVWDQAGRELIDFAGGIAVNVLGHAHPALVGALTEQANKLWHVSNVF
TNEPALRLAHKLIDATFAERVFFCNSGAEANEAAFKLARRVAFDRFGTEKYEIIAALNSFHGRTLFTVNVGGQSKYSDGF
GPKITGITHVPYNDLAALKAAVSDKTCAVVLEPIQGEGGVLPAELAYLQGARELCDANNALLVFDEVQTGMGRTGNLFAY
QHYGVTPDILTSAKSLGGGFPIAAMLTTEALAKHLVVGTHGTTYGGNPLACAVAEAVIDVINTPEVLNGVHAKHDKFKTR
LQQIGEKYGLFTQVRGLGLLIGCVLSDAWKGKAKDIFNAAEQEGLMILQAGPDVIRFAPSLVVEDADIDAGLDRFERAAA
KLTQA

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=379, Percent_Identity=35.0923482849604, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI284507298, Length=293, Percent_Identity=36.518771331058, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI13994255, Length=430, Percent_Identity=29.3023255813954, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI37574042, Length=417, Percent_Identity=26.1390887290168, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI226442709, Length=390, Percent_Identity=26.4102564102564, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI226442705, Length=417, Percent_Identity=25.1798561151079, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI24119277, Length=412, Percent_Identity=26.4563106796117, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI188536080, Length=414, Percent_Identity=23.1884057971014, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI38679950, Length=414, Percent_Identity=23.1884057971014, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI38679946, Length=414, Percent_Identity=23.1884057971014, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1789759, Length=406, Percent_Identity=65.5172413793103, Blast_Score=551, Evalue=1e-158,
Organism=Escherichia coli, GI1788044, Length=392, Percent_Identity=63.7755102040816, Blast_Score=526, Evalue=1e-150,
Organism=Escherichia coli, GI1789016, Length=399, Percent_Identity=37.34335839599, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI145693181, Length=380, Percent_Identity=36.3157894736842, Blast_Score=201, Evalue=5e-53,
Organism=Escherichia coli, GI1787560, Length=391, Percent_Identity=35.2941176470588, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1786991, Length=295, Percent_Identity=32.5423728813559, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786349, Length=337, Percent_Identity=30.5637982195846, Blast_Score=115, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI25144271, Length=382, Percent_Identity=35.0785340314136, Blast_Score=230, Evalue=8e-61,
Organism=Caenorhabditis elegans, GI32564660, Length=444, Percent_Identity=30.1801801801802, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI25144274, Length=266, Percent_Identity=35.7142857142857, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI71992977, Length=419, Percent_Identity=26.0143198090692, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17541228, Length=430, Percent_Identity=25.5813953488372, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71981843, Length=160, Percent_Identity=34.375, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324432, Length=392, Percent_Identity=40.3061224489796, Blast_Score=288, Evalue=9e-79,
Organism=Saccharomyces cerevisiae, GI6323470, Length=401, Percent_Identity=32.6683291770574, Blast_Score=202, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6324386, Length=336, Percent_Identity=29.4642857142857, Blast_Score=112, Evalue=9e-26,
Organism=Drosophila melanogaster, GI21357415, Length=383, Percent_Identity=34.9869451697128, Blast_Score=221, Evalue=7e-58,
Organism=Drosophila melanogaster, GI161085790, Length=422, Percent_Identity=31.042654028436, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI28574759, Length=417, Percent_Identity=31.1750599520384, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI21356575, Length=419, Percent_Identity=27.2076372315036, Blast_Score=131, Evalue=7e-31,
Organism=Drosophila melanogaster, GI281366494, Length=432, Percent_Identity=23.6111111111111, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24667139, Length=432, Percent_Identity=23.6111111111111, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24667143, Length=432, Percent_Identity=23.6111111111111, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43270; Mature: 43139

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVEHAAVQRADFDQVMVPNYAPAAFIPVRGAGSRVWDQAGRELIDFAGGIAVNVLGHAH
CCCCHHHHHHCCCCCEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCCC
PALVGALTEQANKLWHVSNVFTNEPALRLAHKLIDATFAERVFFCNSGAEANEAAFKLAR
HHHHHHHHHHHHHHEEHHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHH
RVAFDRFGTEKYEIIAALNSFHGRTLFTVNVGGQSKYSDGFGPKITGITHVPYNDLAALK
HHHHHHCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCEEEECCCHHHHHHH
AAVSDKTCAVVLEPIQGEGGVLPAELAYLQGARELCDANNALLVFDEVQTGMGRTGNLFA
HHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECHHHCCCCCCCEEE
YQHYGVTPDILTSAKSLGGGFPIAAMLTTEALAKHLVVGTHGTTYGGNPLACAVAEAVID
EEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHH
VINTPEVLNGVHAKHDKFKTRLQQIGEKYGLFTQVRGLGLLIGCVLSDAWKGKAKDIFNA
HHCCHHHHHCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AEQEGLMILQAGPDVIRFAPSLVVEDADIDAGLDRFERAAAKLTQA
HHHCCEEEEECCCHHHHHCCHHEEECCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVEHAAVQRADFDQVMVPNYAPAAFIPVRGAGSRVWDQAGRELIDFAGGIAVNVLGHAH
CCCHHHHHHCCCCCEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCCC
PALVGALTEQANKLWHVSNVFTNEPALRLAHKLIDATFAERVFFCNSGAEANEAAFKLAR
HHHHHHHHHHHHHHEEHHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHH
RVAFDRFGTEKYEIIAALNSFHGRTLFTVNVGGQSKYSDGFGPKITGITHVPYNDLAALK
HHHHHHCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCEEEECCCHHHHHHH
AAVSDKTCAVVLEPIQGEGGVLPAELAYLQGARELCDANNALLVFDEVQTGMGRTGNLFA
HHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECHHHCCCCCCCEEE
YQHYGVTPDILTSAKSLGGGFPIAAMLTTEALAKHLVVGTHGTTYGGNPLACAVAEAVID
EEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHH
VINTPEVLNGVHAKHDKFKTRLQQIGEKYGLFTQVRGLGLLIGCVLSDAWKGKAKDIFNA
HHCCHHHHHCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AEQEGLMILQAGPDVIRFAPSLVVEDADIDAGLDRFERAAAKLTQA
HHHCCEEEEECCCHHHHHCCHHEEECCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12928499 [H]