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The map label for this gene is ompR [H]

Identifier: 77460418

GI number: 77460418

Start: 4738035

End: 4738763

Strand: Direct

Name: ompR [H]

Synonym: Pfl01_4197

Alternate gene names: 77460418

Gene position: 4738035-4738763 (Clockwise)

Preceding gene: 77460416

Following gene: 77460419

Centisome position: 73.59

GC content: 64.06

Gene sequence:

>729_bases
GTGAACGACGAGCAGAAAGACGACAAGCGCTGGAGCATCCGTGCCCTGATCGTCGACGATGACGTGCCGATCCGCGAACT
GATGATCGACTACCTGGCCCGCTTCAACATTCACGCCAGCGGCGTCACCGACGGCGCGGCGATGCGCCAGGCGATGCAGG
CCGAACATTTCGACGTGGTGGTGCTCGACCTGATGCTGCCCGGCGAGGACGGTCTGTCGCTGTGCCGCTGGCTACGCGCC
GAATCGGACATCCCGATCCTGATGCTCACCGCCCGTTGCGAACCCACCGACCGGATCATCGGCCTGGAACTGGGCGCCGA
TGACTACATGGCCAAACCGTTCGAACCACGGGAACTGGTGGCGCGGATCCAGACGATTCTGCGTCGGGTGCGCGACGACC
GCAGCGAACAGCGTGCGAACATTCGCTTCGACAACTGGCGCCTGAACAGCGTCCTGCGCCAGCTCATCGCTGACGATGGC
CTGGTGGTGCCGCTGTCCAATGCCGAATTCCGCCTGCTCTGGGTGTTCATCGAACGTCCGCGCCGGGTGCTCAGCCGCGA
ACAGTTGCTGGACGCCGCCCGTGGCCGCTCGATCGAAGCCTTCGACCGCAGCATCGACTTGCTGGTCTCGCGTCTGCGGC
AAAAACTCGGCGACGACCCGAAAGCCCCGCAACTGATCAAGACCGTACGTGGTGAAGGCTACCTGTTCGACGCCCGGGAC
ATTGGCTGA

Upstream 100 bases:

>100_bases
CGGCCGGACGCCTATGCTGAAACCACAACCTCGCAGCCTATCTTTGTGGTTGGCGGCCTACTGGCAGATGAACAGCCTCA
TGCACAACTCCCAAGCCTCC

Downstream 100 bases:

>100_bases
TGCGAGCGCGCTTCGACACGCTGTTCGGCCGCCTGTTTGGCATGCTGTTGGTGGCGATCGTCCTGGCGCACTTGCTGGCC
TTCGCCTGGTTCCGCCTCTA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MNDEQKDDKRWSIRALIVDDDVPIRELMIDYLARFNIHASGVTDGAAMRQAMQAEHFDVVVLDLMLPGEDGLSLCRWLRA
ESDIPILMLTARCEPTDRIIGLELGADDYMAKPFEPRELVARIQTILRRVRDDRSEQRANIRFDNWRLNSVLRQLIADDG
LVVPLSNAEFRLLWVFIERPRRVLSREQLLDAARGRSIEAFDRSIDLLVSRLRQKLGDDPKAPQLIKTVRGEGYLFDARD
IG

Sequences:

>Translated_242_residues
MNDEQKDDKRWSIRALIVDDDVPIRELMIDYLARFNIHASGVTDGAAMRQAMQAEHFDVVVLDLMLPGEDGLSLCRWLRA
ESDIPILMLTARCEPTDRIIGLELGADDYMAKPFEPRELVARIQTILRRVRDDRSEQRANIRFDNWRLNSVLRQLIADDG
LVVPLSNAEFRLLWVFIERPRRVLSREQLLDAARGRSIEAFDRSIDLLVSRLRQKLGDDPKAPQLIKTVRGEGYLFDARD
IG
>Mature_242_residues
MNDEQKDDKRWSIRALIVDDDVPIRELMIDYLARFNIHASGVTDGAAMRQAMQAEHFDVVVLDLMLPGEDGLSLCRWLRA
ESDIPILMLTARCEPTDRIIGLELGADDYMAKPFEPRELVARIQTILRRVRDDRSEQRANIRFDNWRLNSVLRQLIADDG
LVVPLSNAEFRLLWVFIERPRRVLSREQLLDAARGRSIEAFDRSIDLLVSRLRQKLGDDPKAPQLIKTVRGEGYLFDARD
IG

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=44.7826086956522, Blast_Score=195, Evalue=3e-51,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=36.7256637168142, Blast_Score=161, Evalue=4e-41,
Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=40.6113537117904, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=37.9310344827586, Blast_Score=147, Evalue=9e-37,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=38.5964912280702, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=37.5, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=33.4782608695652, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1790860, Length=219, Percent_Identity=36.986301369863, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI87082012, Length=226, Percent_Identity=30.5309734513274, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1786784, Length=237, Percent_Identity=35.0210970464135, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1789402, Length=230, Percent_Identity=31.7391304347826, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=34.3478260869565, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1786911, Length=179, Percent_Identity=36.3128491620112, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI1787375, Length=234, Percent_Identity=33.7606837606838, Blast_Score=101, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27894; Mature: 27894

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDEQKDDKRWSIRALIVDDDVPIRELMIDYLARFNIHASGVTDGAAMRQAMQAEHFDVV
CCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHCCCCEE
VLDLMLPGEDGLSLCRWLRAESDIPILMLTARCEPTDRIIGLELGADDYMAKPFEPRELV
EEEEEECCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCHHHHH
ARIQTILRRVRDDRSEQRANIRFDNWRLNSVLRQLIADDGLVVPLSNAEFRLLWVFIERP
HHHHHHHHHHHHCHHHHHCCCEECCEEHHHHHHHHHCCCCEEEEECCCCEEEEEEEHHHH
RRVLSREQLLDAARGRSIEAFDRSIDLLVSRLRQKLGDDPKAPQLIKTVRGEGYLFDARD
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEECCCC
IG
CC
>Mature Secondary Structure
MNDEQKDDKRWSIRALIVDDDVPIRELMIDYLARFNIHASGVTDGAAMRQAMQAEHFDVV
CCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHCCCCEE
VLDLMLPGEDGLSLCRWLRAESDIPILMLTARCEPTDRIIGLELGADDYMAKPFEPRELV
EEEEEECCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCHHHHH
ARIQTILRRVRDDRSEQRANIRFDNWRLNSVLRQLIADDGLVVPLSNAEFRLLWVFIERP
HHHHHHHHHHHHCHHHHHCCCEECCEEHHHHHHHHHCCCCEEEEECCCCEEEEEEEHHHH
RRVLSREQLLDAARGRSIEAFDRSIDLLVSRLRQKLGDDPKAPQLIKTVRGEGYLFDARD
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEECCCC
IG
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]