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The map label for this gene is yfmJ [H]

Identifier: 77460416

GI number: 77460416

Start: 4735963

End: 4736967

Strand: Direct

Name: yfmJ [H]

Synonym: Pfl01_4195

Alternate gene names: 77460416

Gene position: 4735963-4736967 (Clockwise)

Preceding gene: 77460412

Following gene: 77460418

Centisome position: 73.56

GC content: 61.09

Gene sequence:

>1005_bases
ATGACCAACCAGACCAATCGTCAGTTCCTGCTCGCCAAACGCCCGGCGGGCGCCGCCACCCGCGAGACCTTCACCTATCA
GGAACTCCCGGTCGGCGAGCCGGCGGCGGGGCAGATTCTGGTCAAGAACGAATACCTGTCCCTCGATCCGGCCATGCGCG
GCTGGATGAACGAAGGCAAATCCTACATTCCGCCGGTGGGTCTGGGCGAAGTCATGCGCGCACTGGGCGTGGGTAAAGTC
GTCGCGTCAAACAATCCGGGGTTTGCCGTCGGCGACTACGTCAACGGTGCCATTGGCGTGCAGGATTATTTCCTCGGCGA
GCCAAAAGGTTTCTACAAGGTCGATCCGAAACTGGCACCGCTACCGGTTTATCTGTCCGCACTGGGCATGACCGGCATGA
CCGCCTACTTCGCCCTGCTCGATGTCGGCGCACCGAAGGCCGGCGATACCGTGGTGTTATCTGGTGCAGCGGGCGCGGTC
GGCAGCATTGCCGGGCAGATTGCCAAAATCAAAGGCTGTCGGGTGATCGGGATCGCCGGTGGCGCGGACAAGTGCAAGTT
CCTGGTCGATGAACTGGGCTTCGACGGCGCCATCGACTACAAAAGCGAAGACGTGCTCGCCGGTCTCAAACGCGAATGCC
CGAAAGGCGTGGACGTGTATTTCGACAACGTCGGCGGCGACATCCTCGACGCGGTGCTGAGCCGCCTGAACTTCAAGGCG
CGCGTGGTGATCTGCGGCGCGATCAGCCAGTACAACAACAAGGAAGCCGTCAAAGGTCCGGCCAACTACCTGTCGCTGCT
GGTCAACCGCGCGCGGATGGAAGGCTTCGTGGTGATGGATTACGCCGCGCAGTACGCCAGCGCCGCCCAGGAAATGGCCG
GCTGGATGGCCAAGGGTCAGCTCAAGAGCAAGGAAGACATCGTCGAAGGCCTGGAAACATTCCCGGAAACCCTGGGCAAA
CTGTTCAGCGGCGAGAACTTCGGCAAACTGGTATTGAAAGTCTGA

Upstream 100 bases:

>100_bases
TCACCGTACTGGATCGGCCTGCATTCGCCCCGTGAGCCAACCTTGCGGCATCGCTCATGAAGGTCTATCAACAAGGCTTC
ATTCAACTCGAGTGCCAGTC

Downstream 100 bases:

>100_bases
AAACAGTGAAGGGAGCCATCGGGCTCCCTTCTTTGATGCTTCAGCTGTTCGCTCAGGCCAGTTCGGCAACCACCGAGGCC
AGGGCCTTGGCCGGATCCGC

Product: zinc-containing alcohol dehydrogenase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MTNQTNRQFLLAKRPAGAATRETFTYQELPVGEPAAGQILVKNEYLSLDPAMRGWMNEGKSYIPPVGLGEVMRALGVGKV
VASNNPGFAVGDYVNGAIGVQDYFLGEPKGFYKVDPKLAPLPVYLSALGMTGMTAYFALLDVGAPKAGDTVVLSGAAGAV
GSIAGQIAKIKGCRVIGIAGGADKCKFLVDELGFDGAIDYKSEDVLAGLKRECPKGVDVYFDNVGGDILDAVLSRLNFKA
RVVICGAISQYNNKEAVKGPANYLSLLVNRARMEGFVVMDYAAQYASAAQEMAGWMAKGQLKSKEDIVEGLETFPETLGK
LFSGENFGKLVLKV

Sequences:

>Translated_334_residues
MTNQTNRQFLLAKRPAGAATRETFTYQELPVGEPAAGQILVKNEYLSLDPAMRGWMNEGKSYIPPVGLGEVMRALGVGKV
VASNNPGFAVGDYVNGAIGVQDYFLGEPKGFYKVDPKLAPLPVYLSALGMTGMTAYFALLDVGAPKAGDTVVLSGAAGAV
GSIAGQIAKIKGCRVIGIAGGADKCKFLVDELGFDGAIDYKSEDVLAGLKRECPKGVDVYFDNVGGDILDAVLSRLNFKA
RVVICGAISQYNNKEAVKGPANYLSLLVNRARMEGFVVMDYAAQYASAAQEMAGWMAKGQLKSKEDIVEGLETFPETLGK
LFSGENFGKLVLKV
>Mature_333_residues
TNQTNRQFLLAKRPAGAATRETFTYQELPVGEPAAGQILVKNEYLSLDPAMRGWMNEGKSYIPPVGLGEVMRALGVGKVV
ASNNPGFAVGDYVNGAIGVQDYFLGEPKGFYKVDPKLAPLPVYLSALGMTGMTAYFALLDVGAPKAGDTVVLSGAAGAVG
SIAGQIAKIKGCRVIGIAGGADKCKFLVDELGFDGAIDYKSEDVLAGLKRECPKGVDVYFDNVGGDILDAVLSRLNFKAR
VVICGAISQYNNKEAVKGPANYLSLLVNRARMEGFVVMDYAAQYASAAQEMAGWMAKGQLKSKEDIVEGLETFPETLGKL
FSGENFGKLVLKV

Specific function: Putative quinone oxidoreductase that may contribute to the degradation of aromatic compounds (Potential) [H]

COG id: COG2130

COG function: function code R; Putative NADP-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADP-dependent oxidoreductase L4BD family [H]

Homologues:

Organism=Homo sapiens, GI226246682, Length=342, Percent_Identity=37.1345029239766, Blast_Score=215, Evalue=5e-56,
Organism=Homo sapiens, GI226246680, Length=342, Percent_Identity=37.1345029239766, Blast_Score=215, Evalue=5e-56,
Organism=Homo sapiens, GI22748929, Length=342, Percent_Identity=37.1345029239766, Blast_Score=215, Evalue=5e-56,
Organism=Homo sapiens, GI226059159, Length=333, Percent_Identity=33.9339339339339, Blast_Score=184, Evalue=8e-47,
Organism=Homo sapiens, GI226059133, Length=333, Percent_Identity=33.9339339339339, Blast_Score=184, Evalue=8e-47,
Organism=Homo sapiens, GI226056130, Length=306, Percent_Identity=33.3333333333333, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI28557745, Length=343, Percent_Identity=30.9037900874636, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI194239674, Length=281, Percent_Identity=25.6227758007117, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI13236495, Length=281, Percent_Identity=25.6227758007117, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI226510941, Length=336, Percent_Identity=43.1547619047619, Blast_Score=289, Evalue=2e-79,
Organism=Caenorhabditis elegans, GI133901710, Length=354, Percent_Identity=34.4632768361582, Blast_Score=187, Evalue=7e-48,
Organism=Caenorhabditis elegans, GI133901712, Length=354, Percent_Identity=34.4632768361582, Blast_Score=187, Evalue=7e-48,
Organism=Caenorhabditis elegans, GI17536829, Length=336, Percent_Identity=27.0833333333333, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323504, Length=331, Percent_Identity=34.7432024169184, Blast_Score=137, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6319520, Length=330, Percent_Identity=28.4848484848485, Blast_Score=70, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00107 ADH_zinc_N [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35446; Mature: 35315

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNQTNRQFLLAKRPAGAATRETFTYQELPVGEPAAGQILVKNEYLSLDPAMRGWMNEGK
CCCCCCCEEEEEECCCCCCHHHCEEECCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCC
SYIPPVGLGEVMRALGVGKVVASNNPGFAVGDYVNGAIGVQDYFLGEPKGFYKVDPKLAP
CCCCCCCHHHHHHHHCCCEEEECCCCCEEECCCCCCCCCCHHHHCCCCCCCEEECCCCCC
LPVYLSALGMTGMTAYFALLDVGAPKAGDTVVLSGAAGAVGSIAGQIAKIKGCRVIGIAG
HHHHHHHHCHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEEECC
GADKCKFLVDELGFDGAIDYKSEDVLAGLKRECPKGVDVYFDNVGGDILDAVLSRLNFKA
CCHHHHHHHHHCCCCCEECCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCEE
RVVICGAISQYNNKEAVKGPANYLSLLVNRARMEGFVVMDYAAQYASAAQEMAGWMAKGQ
EEEEEEEHHHCCCCCCCCCHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHCCC
LKSKEDIVEGLETFPETLGKLFSGENFGKLVLKV
CCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
>Mature Secondary Structure 
TNQTNRQFLLAKRPAGAATRETFTYQELPVGEPAAGQILVKNEYLSLDPAMRGWMNEGK
CCCCCCEEEEEECCCCCCHHHCEEECCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCC
SYIPPVGLGEVMRALGVGKVVASNNPGFAVGDYVNGAIGVQDYFLGEPKGFYKVDPKLAP
CCCCCCCHHHHHHHHCCCEEEECCCCCEEECCCCCCCCCCHHHHCCCCCCCEEECCCCCC
LPVYLSALGMTGMTAYFALLDVGAPKAGDTVVLSGAAGAVGSIAGQIAKIKGCRVIGIAG
HHHHHHHHCHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEEECC
GADKCKFLVDELGFDGAIDYKSEDVLAGLKRECPKGVDVYFDNVGGDILDAVLSRLNFKA
CCHHHHHHHHHCCCCCEECCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCEE
RVVICGAISQYNNKEAVKGPANYLSLLVNRARMEGFVVMDYAAQYASAAQEMAGWMAKGQ
EEEEEEEHHHCCCCCCCCCHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHCCC
LKSKEDIVEGLETFPETLGKLFSGENFGKLVLKV
CCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377 [H]